• 대한기관윤리심의기구협의회지
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• 제5권1호
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• pp.21-32
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• 2023

Purspose: The purpose of this study is to examine the meaning and definition of vulnerable subjects in clinical trials in light of domestic and international regulations and guidelines, to analyze the contents of standard operation procedures (SOPs) among advanced general hospitals in Korea that conduct clinical trials, and to examine deliberation procedures for operation plans. Methods: The study examined how vulnerable research subjects were defined and described in related regulations and the classification of vulnerable research subjects presented in the IRB/HRPP SOPs of 18 clinical trial institutions, including 11 AAHRPP-accreditated general hospitals in Korea, as well as the operation of the IRB deliberation. Results: Among all domestic and international regulations and guidelines, only the The Council for International Organization of Medical Sciences (CIOMS) guidelines explain why vulnerability is related to judgments on the severity of physical, psychological, and social harm, why individuals are vulnerable, and for what reasons. However, the classification of vulnerable subjects by institutions differed from the classification by the International Conference on Harmonization-Good Clinical Practice (ICH-GCP). A total of the 16 institutions classified children and minors as vulnerable research subjects. 14 institutions classified subjects who cannot consent freely were classified as vulnerable subjects. 15 institutions classified sujects who can be affected by the organizational hierarchy were classified as vulnerable subjects. Subjects in emergency situations were regarded as vulnerable research subjects in 8 of institutions, while people in wards, patients with incurable diseases, and the economically poor including the unemployed were categorized as vulnerable research subjects in 7, 4, and 4 of institutions, respectively. Additionally, some research subjects were not classified as vulnerable by ICH-GCP but were classified as vulnerable by domestic institutions 15 of the institutions classified pregnant women and fetuses as vulnerable, 11 classified the elderly as vulnerable, and 6 classified foreigners as vulnerable. Conclution: The regulations and institutional SOPs classify subjects differently, which may affect subject protection. There is a need to improve IRBs' classifications of vulnerable research subjects. It is also necessary to establish the standards according to the differences in deliberation processes. Further, it is recommended to maintain a consistent review of validity, assessment of risk/benefit, and a review using checklists and spokeperson. The review of IRB is to be carried out in a manner that respects human dignity by taking into account the physical, psychological, and social conditions of the subjects.

• 한국의류학회지
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• 제12권1호
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• pp.45-52
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• 1988

To classify the foot type, direct measurements, metatarso-phalanx angle and foot print angle of the right and left foot were measured and analyzed. The results are as follows. 1. The correlation coefficients between right and left foot were high degree, and except medial malleous height, the diffences between right and left foot are not significant. 2. The correlation coefficient among direct measurements of the foot are high degree, tut the correlation coefficients between direct measurements and metatarso-phalanx angle and foot print angle are no or low degree. Therefore, to recognize the foot type, the direct measurements, metatarso-phalanx angle and foot print angle need to be measured independently. 3. According to foot width/foot $length{\times}100$ which is the slender degree of foot, three groups are distinguished: one is slender type of which foot width/foot $length{\times}100$ is less than $40.14\%$, two is standard type of which foot width/foot $length{\times}100$ is $40.14\%{\~}44.30\%$, three is broad type of which foot width/foot $length{\times}100$ is more than $44.30\%$. 4. On the photographs metatarso-phalanx angle was measured, and two groups are distinguished: one is normal type of which the metatarso-phalanx angle is more than $160^{\circ}$ and the other is the deformed type of which the metatarso-Phalanx angle is less than $159^{\circ}$. 5. By foot print angle $30^{\circ}$ which need reformation of the foot, two groups are distinguished: one is normal foot print angle of which the angle is more than $30^{\circ}$ and the other is flat foot print angle of which the angle is less than $30^{\circ}$. 6. Classifications by foot width/foot $length{\times}100$, metatarso-Phalanx angle and foot Print angle are put together, and then foot types are classified into 12 groups such as Table 11.

• 한방안이비인후피부과학회지
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• 제22권3호
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• pp.153-166
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• 2009

Objectives : This study was planed to evaluate clinical status of the alopecia patients who had visited Korean medicine clinic. And the result from this study would provide a standard in Korean medical diagnostic and classification method of alopecia. Methods : Clinical records of 183 patients with alopecia seen from January 2004 to April 2005 at Korean medical clinic was examined. They were classified into 4 different types according to chief complains besides alopecia by 2 Korean medical doctors. Results and conclusions : We made clinical analysis of patients of alopecia from January 2004 to April 2005. Among the alopecia patients who visit Korean medical clinic, people age between 20 and 30 had high ratio. The duration from the recognition of initial hair loss to the time of the first visit to the Korean medical clinic was less than 12 months in 20.8%(38/138), and less than 60 months in 72.2% (132/183). The condition of alopecia was more worse than other alopecia patients who visit the west medical clinic. Also the ratio with increased temperature of face or scalp is chief complaint except alopecia in alopecia patients was high in men and the ratio with dysfunction of digestive system or chronic weakness was high in women. Among the incidence of alopecia, the androgenic alopecia was most in number; 43.7%(80/183) and the sex distribution showed 83 men and 100 women.

• 건축역사연구
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• 제25권5호
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• pp.75-86
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• 2016

This paper examines the pagodas during the Bagan period, which are thought to be most valuable among those in Myanmar. They have not been sufficiently studied, in spite of their high Buddhist status. It considers the contemplation of Pato, their formal characteristics in the Bagan period and the formal categorizations of pagodas in the same period. Thus, following seven kinds of conclusions are derived: first, researchers provide opinions to the Pato which should be regarded as the Buddhist shrine-type of pagoda with a unique Bagan form, symbolically indicating that Theravada Buddhism incorporated Hinduism; second, the terraces were characteristic components in pagodas, during the Bagan period, which were built after the enthronement of King Anawratha and are thought to symbolically express the wish to widely spread Theravada Buddhism; third, Shwesandaw Zedi seems to affect not only Shwezigon Zedi, a representative standard form of pagoda in Myanmar, but also Ananda Pato; fourth, it is thought to be proper to examine the terraces by classifying them into lower, central(from pedestals to Angryeon and Bokryeon) and upper part, if it intends to divide a pagoda with bell-shaped body on the terraces during the Bagan period, into three parts; fifth, the Pato may be identified as a form of pagoda during the Bagan period, and such a form can be classified as that of Sikhara on the rectangular terrace; sixth, forms of Myanmar's pagodas can be classified into fourteen kinds of them, and they may be also grouped into transmitted, general and special type; and seventh, on the basis of the findings, it is thought that the pagodas during the Bagan period may be classified into six forms, and they can be largely categorized into transmitted, general and special type.

• Journal of the Korean Data and Information Science Society
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• 제27권6호
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• pp.1443-1452
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• 2016

본 연구는 소상공인과 임차상인 보호정책을 지원하고, 권리금 분쟁소송 등에 참고자료로 활용할 뿐만 아니라 상가권리금 현황 파악을 위한 최초 조사를 실시하기 위한 표본설계 연구이다. 개별 임차 사업체 단위로 발생하는 권리금의 특성상 통계청의 전국사업체조사를 모집단으로 활용 하였으며, 우선적인 정보 제공이 필요한 7개 도시지역을 반영하였다. 전체 표본수는 8,000개로 하였으며, 7개 도시지역을 부차모집단으로 하고 지역별 상권별 표본수는 비례배분 하였으며, 상권내 업종은 제곱근비례배분 하였다. 목표오차를 활용하여 최종 표본수를 조정 하였으며, 표본설계가중치를 이용한 권리금 평균 추정량과 추정오차, 구간추정 공식을 유도하였으며, 이를 통해 도시별 상권별 및 업종별 통계 추정과 추정의 정도에 대한 평가를 가능하게 하였다.

• International Journal of Costume and Fashion
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• 제10권1호
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• pp.67-79
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• 2010

Cultural sensation by appearance of Elvis Aaron Presley is thought to have been greatly influenced by spread of popular culture beginning to form with the development of mess media in USA that was changed rapidly after the war, changing aspect of popular music in U.S.A through the media development and teenager culture of USA that has rapidly emerged. Elvis intended to change into 'music to be seen' deviating from 'music to be simply listened to' with expressing the conversion of sexual consciousness, defiance to older generation and a sense of value on wealth, and the like, and also suggested a new culture and style to the young people at that time. Flow of Elvis's fashion may be categorized into the classifications such as the fashion in the period. First, Formative period(before 1954) distinguished by pimp look and sideburns with tough image and wild clothes. Second, Establishment period(1954-57) may be categorized into the hot rockabilly style which showed a glittering fashion by brilliant and colorful costumes, the cool rockabilly style which changed him to a fashionable star of modem image(1958-60). Third, re-heyday(after 1968) where a brilliant and bold decoration was displayed. In Elvis fashion, the masculine sensualism, defiance to main value and expression of luxury and consuming culture, etc. are included as a unique aesthetic consciousness. 'Expression of masculine sensualism' represented the sensualism through sexual objectification of men's body by men's sexual ostentation which was prohibited. 'Defiance to main value' means that attempts of non-mainstream image for social class are expressed with an exercise of power by young people through the public. Although the Elvis look has fanned an anti-culture, it was expressed and accepted as having a normally capitalistic appearance. In addition, it being thought of as the standard, symbolizing a success and a wealth through the presentation of image which accepted this material benefit, we may classify this into 'expression of luxury and consuming culture'.

• 대한한의학회지
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• 제16권1호통권29호
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• pp.132-140
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• 1995

Object : This study is designed to evaluate the correlation between the data of DITI(Digital Infrared Thermographic Imaging)examination and the changes of clinical symptom after the therapy of acupuncture in the patients with herniated cervical intervertebral disc. Content : The conservative therapy with acupuncture was performed during $4{\sim}5$ weeks, The acupuncture points of SI3, B62, TE3, G34, LI4, S36, GV26, G21, SII5 were used. In the pre- and post therapy, DITI examinations were performed in patients who had HIVD and were treated by acupuncture simultaneously, and then tried to correlate the results of clinical symptoms with the difference of thermographic findings at pre-acupuncture and post-acupuncture. Setting : The standard routine thermoghaphic examinations were performed with thermography(DITI) in the 15 patients with lumbar disc herniations at pre- and post acupuncture. Patient : Thermographic imaging of 15 cases were analyzed. They has disc herniations in X-ray, CT scan and MRI and they were treated by acupuncture theraphy in our hospital from March, 1994 to January, 1995. Result : 1) The causes were trauma(60%), retention of phlegm and fluid(8.7%) and cold & moisture(33.3%) 2) Levels of herniated cervical disc are C2/3(1 case). C3/4(2 cases), C5/6 & C6/7 (2 cases), C6/7(4 cases), Normal(6 cases). 3) Classifications of thermographic pattern are radiculopathy(80%), spot(13.3%), and nonspecific(6.7%) in order. 4) In evaluation Results of clinical symptom are Excellent(80%), Good(6.7%), and Poor(6.7%). Data of DITI are Excellent(80%), Good(6.7%), Fair(6.7%), and Poor(6.7%). Conclusion ; Acupuncture showed good results over 86.7% in clinical evaluation and 86.7% in DITI. Thermographic examination was valuable in the evaluation of therapeutic effect of acupuncture treatment.

• 한국의료질향상학회지
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• 제10권2호
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• pp.204-215
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• 2003

Background : ICD-10 Classification, which is used domestically as well as internationally, has limited use in the clinical practice since it is developed for at disease statistics and epidemiology. Therefore, the purposes of this study were to improve the quality of diagnosis by constructing a new disease classification based on the diagnoses doctors currently make in the clinical setting and connecting this classification with OCS and EMR, and to meet the demands of doctors for high quality medical study data in medical research. Methods : The specialists in each ophthalmic subfield collected clinical diagnoses and abbreviations based on the ophthalmology textbooks and confirmed the classifications. Total number of clinical diagnoses collected was totaled 672, for which ideal diagnoses had been selected and a new model of disease classification model in connection with ICD-10 was constructed. The constructed classification of clinical diagnoses consisted of six steps: the first step was the classification by ophthalmic subspecialty field; the second to fifth steps were the detailed classification by each specialty field; the sixth step was the classification by site. Results : After introducing the new disease classification, research on the use and a pre-post comparison was conducted. The result from the research on the use of the clinical diagnoses in inpatient and outpatient care has shown a gradually increasing tendency. From the pre-post comparison of EMR discharge summary diagnoses, the result demonstrated that the diagnosis was stated correctly and in detail. Since the diagnosis was stated correctly, code classification became correct as well, which makes it possible to construct high quality medical DB. Conclusion : This construction of clinical diagnoses provides the medical team with high quality medical information. It is also expected to increase the accuracy and efficiency of service in the department of medical record and department of insurance investigation. In the future, if hospitals wish to construct a classification of clinical diagnosis and a standard proposal of clinical diagnosis is presented by a medical society, the standardization of diagnosis seems to be possible.

• Nutritional Sciences
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• 제7권2호
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• pp.98-106
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• 2004

The dietary vitamin $B_6$ intake of 185 Korean children aged 7-12 years (y), who showed no health problems, in the Seoul area and its sources were estimated using a modified Korean vitamin $B_6$ database. The age and sex of each subject was classified according to the classifications in the Korean Recommended Dietary Allowance (RDA). Dietary vitamin $B_6$ intake and food sources were estimated using the three-day recall method with the help of a trained interviewer. Food portion sizes were estimated by using standard household measures and published average portion sizes. The average daily vitamin $B_6$ intake was 1.69$\pm$0.50 mg/d in children aged 7-9 y, 1.86$\pm$0.44 mg/d in male children aged 10-12 y and 1.77$\pm$0.62 mg/d in female children aged 10-12 y. Less than 5% of the subjects consumed less than the Korean RDA of vitamin $B_6$. The average ratio of vitamin $B_6$intake to daily protein intake was 0.028$\pm$0.006 mg/g in children aged 7-9 y, 0.028$\pm$0.004 mg/g in male children aged 10-12 y and 0.029$\pm$0.007 mg/g in female children aged 10-12 y. The intake of vitamin $B_6$ was significantly (p<.01) positively correlated to the intake of all other nutrients. Foods from animal and plant sources provided 37% and 73% respectively, of total vitamin $B_6$. Major dietary sources of vitamin $B_6$ in children in the Seoul area were rice, soybean sprouts, pork, beef, cereal, kimchi, milk, onions, and potatoes. As for major dietary sources of vitamin $B_6$, the top 20 foods provided nearly 73-75% of the total vitamin $B_6$ consumed by Korean children.

• International Journal of Fluid Machinery and Systems
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• 제9권3호
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• pp.245-255
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• 2016

The alternating flow hydraulics (AFH) had demonstrated the unique features in the past. One of the most well-known inventions was the hydraulic machine-gun synchronizer, which had become the standard equipment of airplane during World War I. The studies on the AFH between 1960 and 1980 had trigged many researchers' interests and reached the summit. The disadvantages of the AFH like low efficiency and cooling difficulty had prevented the further development. Few people are engaged in studying the AFH at present. However, the unique characteristics of the AFH inspire the researchers to continuously explore the new special suitable applications. The overviews of the AFH and the new potential application in the geotechnical testing field have been discussed in this paper. First, the research results of the AFH in the past have been summarized. Then, the classifications of the AFH have been introduced in detail according to the working principle, the number of hydraulic transmission pipelines and the mode of input energy. The advantages and the disadvantages of the AFH have been discussed. A novel potential suitable application in the soil test field has been presented at last. The detailed designing ideas of a new dynamic trixial instrument have been given, which will be a more innovational and energy-saving plan according to the current studies. A series of simulation experiments have been done. The simulation results show that the proposed scheme for the new dynamic trixial instrument is feasible. The paper work will also give some inspirations in the reciprocating motion control system.