• Journal of Veterinary Clinics
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• v.40 no.2
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• pp.113-118
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• 2023

Skin and joint diseases are relatively common in dogs. Nutritional complementation is one of the various management strategies for these disorders. This study evaluated the safety and clinical efficacy of Kyungokgo-gamibang in dogs with skin and joint diseases. Thirty dogs with diseases were included and divided into three groups: control group (n = 15), skin group (n = 10), and joint group (n = 5). The skin and joint groups were fed skin and joint gums composed of Kyungokgo-gamibang extract with standard treatment for four weeks. The control group included dogs with skin diseases who were administered standard skin infection treatment for 4 weeks. The physical and laboratory results showed no remarkable adverse effects of Kyungokgo-gamibang extract after its administration in dogs. Clinical efficacy was evaluated using quality of life scale, and levels of cytokines, including interferon-γ, interleukin (IL)-2, IL-6, IL-8, IL-10, monocyte chemoattractant protein-1, and tumor necrosis factor-α, for 4 weeks in all groups. Dermatologic clinical scales were performed for 4 weeks in the control and skin groups. Both the control and skin groups had significantly decreased dermatologic clinical scales, including pruritus and erythema scales (p < 0.05). Among the cytokine levels, only IL-2 concentration was significantly decreased in the skin group after 4 weeks of administration of the Kyungokgo-gamibang extract (p = 0.032). There was no significant difference between the levels of cytokines on days 0 and 28 in the joint group. The quality of life scale was significantly increased after week 4 compared to week 0 in the skin (p = 0.008) and joint groups (p = 0.041). This study suggests that Kyungokgo-gamibang extract can be applied in managing dogs affected by skin and joint diseases without adverse effects.

• Journal of Life Science
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• v.14 no.5
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• pp.778-787
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• 2004

Effect of the microbial product made of Bacillus stearothermophilus DL-3, which was isolated from the soil and identified in this study, and rice bran on microorganisms in soil and growth of lettuce (Red skirt lettuce) and Chinese cabbage (Ga rack new No.1 Chinese cabbage) was investigated. Total numbers of microorganisms in the pot with untreated soil, treated with standard amount of microbial product and treated with double amounts of microbial product for growth of lettuce after 6 weeks were 2.78${\times}$10$^{7}$ CFU/g, 2.72${\times}$10$^{8}$ CFU/g and 3.63${\times}$10$^{8}$ CFU/g. Total numbers of microorganisms in the soil without treatment of microbial product and treated with standard amount of microbial product were 2.06${\times}$10$^{8}$ CFU/g and 5.49${\times}$10$^{8}$ CFU/g. Total numbers of microorganisms in the pot with untreated soil, treated with standard amount of microbial product and treated with double amounts of microbial product for growth of Chinse cabbage after 6 weeks were 1.43${\times}$10$^{7}$ CFU/g, 3.42${\times}$10$^{8}$ CFU/g and 7.22${\times}$10$^{8}$ CFU/g. Total numbers of microorganisms in the soil without treatment of microbial product and treated with standard amount of microbial product were 5.75${\times}$10$^{8}$ CFU/g and 7.96${\times}$10$^{8}$ CFU/g. On basis of leaf length, leaf width, leaf number, wet weight and dry weight, the growth of lettuce and Chinese cabbage on the soil treated with microbial product was faster than that on the untreated soil. The treatment of microbial product in the soil resulted in the increase of useful microorganisms, which seemed to enhance the growth of lettuce and Chinese cabbage.

• Journal of Chest Surgery
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• v.31 no.9
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• pp.877-883
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• 1998

Background: Cardiopulmonary bypass(CPB), a standard adjunct for open heart surgery, can also play an important role in treating patients with noncardiac diseases. Material and Method: We report a collective analysis of noncardiac applications of cardiopulmonary bypass experienced at Seoul National University Hospital from 1969 to 1996. Out of a total of 20 patients, 8 were treated for membranous obstruction of inferior vena cava(MOVC), 5 for malignant melanoma, 3 for pulmonary embolism, 1 for double lung transplantation, 1 for intracranial giant aneurysm(GA), 1 for renal cell carcinoma(RC), and 1 for liposarcoma. CPB was used to induce profound hypothermia with circulatory arrest in 6 patients(MOVC 4, GA 1, RC 1). Result: CPB time was 113 mins on average for MOVC, 161 mins for GA, and 156 mins for RC, while the lowest rectal temperature was 26$^{\circ}C$ on average in MOVC, and 19$^{\circ}C$ in GA and RC. Postoperative recovery was good in all MOVC patients. The patient with GA, who underwent reoperation for the removal of hematoma, died 14 days postoperatively. The patient with RC recovered from the operation in a good condition but died from metastatic spread 6 months later. CPB was instituted for pulmonary embolectomy in 3 patients, in whom postoperative courses were uneventful, except in 1 patient who showed transient neurologic symptoms. CPB was used in a patient with double-lung transplantation for hemodynamic and ventilatory support. The patient was weaned successfully from CPB but died from low output and septicemia 19 days postoperatively. CPB without circulatory arrest was used to treat in 4 patients with MOVC. These patients showed good postoperative courses. CPB was used to administer high concentrations of chemotherapeutic agents to the extremities in 6 patients(malignant melanoma 5, recurrent liposarcoma 1). CPB time was 153 mins on average. No complications such as edema and neurologic disability were found. Conclusion: Although CPB has a limited indication in noncardiac diseases, if properly applied, it can be a very useful adjunct in a variety of surgical cases.

• Korean Journal of Ichthyology
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• v.22 no.2
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• pp.132-135
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• 2010

A specimen of Arnoglossus polyspilus (G$\ddot{u}$nther) (229.0 mm standard length) belonging to the family Bothidae, collect from the coastal waters of Jeju Island, represents the first record of the species from Korea. This species is characterized by having caudal fin with two simple rays on both upper and lower margins, several anterior dorsal fin rays somewhat elongated, upper jaw extending to below anterior 1/3 of lower eye, and one gill raker on the upper limb of the first gill arch. We add this species to the Korean fish fauna and propose its new Korean name, "No-rang-ban-jeom-ga-ja-mi".

• Journal of ILASS-Korea
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• v.23 no.3
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• pp.114-121
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• 2018

FT process is a technology of chemical reactions that converts a mixture of carbon monoxide and hydrogen into liquid hydrocarbons. During the FT process unreacted gas, known as Off-gas which has low-calorie, is discharged. In this study, we developed an engine that utilize simulated Off-gas, and studied the characteristics of the engine. The off-gas composition is assumed to be $H_2$ 70%, CO 15%, $CO_2$ 15% respectively. Under stoichiometric air-fuel ratio, the experiment was conducted at WOT and IMEP 0.3 Mpa changing compression ratio. Ignition timing was applied with MBT timing. Maximum indicated thermal efficiency 37% was achieved at compression ratio 15 under WOT. CO, $CO_2$ and $NO_x$ were influenced by changing compression ratio, and CO emission was satisfied with the US Tier 4 standard for nonroad engine over the entire experimental conditions.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.2
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• pp.406-414
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• 2002

A new approach, referred to as a successive zooming genetic algorithm (SZGA), is Proposed for identifying a global solution for continuous optimization problems. In order to improve the local fine-tuning capability of GA, we introduced a new method whereby the search space is zoomed around the design point with the best fitness per 100 generation. Furthermore, the reliability of the optimized solution is determined based on the theory of probability. To demonstrate the superiority of the proposed algorithm, a simple genetic algorithm, micro genetic algorithm, and the proposed algorithm were tested as regards for the minimization of a multiminima function as well as simple functions. The results confirmed that the proposed SZGA significantly improved the ability of the algorithm to identify a precise global minimum. As an example of structural optimization, the SZGA was applied to the optimal location of support points for weight minimization in the radial gate of a dam structure. The proposed algorithm identified a more exact optimum value than the standard genetic algorithms.

• Toxicological Research
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• v.29 no.3
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• pp.211-215
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• 2013

The trace toxic metal copper was assayed using mercury immobilized on a carbon nanotube electrode (MCW), with a graphite counter and a reference electrode. In this study, a macro-scale convection motor was interfaced with a MCW three-electrode system, in which a handmade MCW was optimized using cyclic- and square-wave stripping voltammetry. An analytical electrolyte for tap water was used instead of an expensive acid or base ionic solution. Under these conditions, optimum parameters were 0.09 V amplitude, 40 Hz frequency, 0.01 V incremental potential, and a 60-s accumulation time. A diagnostic working curve was obtained from 50.0 to 350 ${\mu}g/L$. At a constant Cu(II) concentration of 10.0 ${\mu}g/L$, the statistical relative standard deviation was 1.78% (RSD, n = 15), the analytical accumulation time was only 60 s, and the analytical detection limit approached 4.6 ${\mu}g/L$ (signal/noise = 3). The results were applied to non-treated drinking water. The content of the analyzed copper using 9.0 and 4.0 ${\mu}g/L$ standards were 8.68 ${\mu}g/L$ and 3.96 ${\mu}g/L$; statistical values $R^2$ = 0.9987 and $R^2$ = 0.9534, respectively. This method is applicable to biological diagnostics or food surveys.

• Journal of Electrical Engineering and Technology
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• v.4 no.2
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• pp.185-193
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• 2009

This paper presents a methodology for photovoltaic (PV) system allocation in distribution systems using a discrete particle swarm optimization (DPSO). The PV allocation problem is in the category of mixed integer nonlinear programming and its formulation may include multi-valued dis-crete variables. Thus, the PSO requires a scheme to deal with multi-valued discrete variables. This paper introduces a novel multi-level quantization scheme using a sigmoid function for discrete particle swarm optimization. The technique is employed to a standard PSO architecture; the same velocity update equation as in continuous versions of PSO is used but the particle's positions are updated in an alternative manner. The set of multi-level quantization is defined as integer multiples of powers-of-two terms to efficiently approximate the sigmoid function in transforming a particle's position into discrete values. A comparison with a genetic algorithm (GA) is performed to verify the quality of the solutions obtained.

• Journal of Power System Engineering
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• v.21 no.6
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• pp.56-61
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• 2017

The check valves are mechanical valves that permit fluids to flow in only one direction, preventing flow from reversing. It is classified as one way directional valves. There are various types of check valves that used in a marine application. A lift type check valve uses the disc to open and close the passage of fluid. The disc lift up from seat as pressure below the disc increases, while drop in pressure on the inlet side or a build up of pressure on the outlet side causes the valve to close. An important concept in check valves is the cracking pressure which is the minimum upstream pressure at which the valve will operate. On the other hand, optimization is a process of finding the best set of parameters to reach a goal while not violating certain constraints. The AMESim software provides NLPQL(Nonlinear Programming by Quadratic Lagrangian) and genetic algorithm(GA) for optimization. NLPQL is the implementation of a SQP(sequential quadratic programming) algorithm. SQP is a standard method, based on the use of a gradient of objective functions and constraints to solve a non-linear optimization problem. A characteristic of the NLPQL is that it stops as soon as it finds a local minimum. Thus, the simulation results may be highly dependent on the starting point which user give to the algorithm. In this paper, we carried out optimization design of the check valve with NLPQL algorithm.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.1080-1085
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• 2005

A hybrid control scheme is proposed for the stabilization of backward movement along simple paths for a vehicle composed of a truck and six trailers. The hybrid comprises the combination of a linear quadratic regulator (LQR) and a neurocontroller (NC) that is trained by a genetic algorithm (GA). Acting singly, either the NC or the LQR are unable to perform satisfactorily over the entire range of the operation required, but the proposed hybrid is shown to be capable of providing good overall system performance. The evaluation function of the NC in the hybrid design has been modified from the conventional type to incorporate both the squared errors and the running steps errors. The reverse movement of the trailer-truck system can be modeled as an unstable nonlinear system, with the control problem focusing on the steering angle. Achieving good backward movement is difficult because of the restraints of physical angular limitations. Due to these constraints the system is impossible to globally stabilize with standard smooth control techniques, since some initial states necessarily lead to jack-knife locks. This paper demonstrates that a hybrid of neural networks and LQR can be used effectively for the control of nonlinear dynamical systems. Results from simulated trials are reported.