• Journal of Oriental Neuropsychiatry
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• v.29 no.4
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• pp.239-253
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• 2018

Objectives: This is one of the manuals of East-West integrative medicine, which was created by the Committee on integrative medicine of Chung-Yeon Korean Medicine Hospital. To support clinical decision making and communication in the East-West cooperative treatment of mild cognitive impairment. Methods: Drafting was based on literature review from the MEDLINE, EMBASE, OASIS, and CNKI databases using search terms such as 'mild cognitive impairment', 'mild neurocognitive disorder', 'acupuncture', 'herbal medicine' and 'traditional Chinese medicine'. An amendment reflecting the goal of consultation and detailed treatment contents was made by reviewing the draft and holding discussion with the rehabilitation specialist of western medicine. The committee then agreed to adopt the manual through the process of review and feedback in addition to face-to-face discussions. Results: This manual contains the diagnosis of mild cognitive impairment, the goal of consultation, and the cooperative treatment contents of the East-West medicine for mild cognitive impairment. Conclusions: This manual provides significant information about the decision making process and contents of treatment in one medical institution for East-West cooperative treatment of mild cognitive impairment.

• Journal of Digital Convergence
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• v.17 no.9
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• pp.279-290
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• 2019

The purpose of this study was to explore communication experiences with doctors experienced by nurses in clinical settings, to resolve communication difficulties, and to identify ways to communicate effectively. "What is communication with a physician experienced by a nurse? The focus of the discussion was performed with questions. The study was a qualitative study of 21 nurses with different clinical experiences using interview methods and analyzed data using the criteria of Downe-Wam bol dt. 12 Themes were reclassified to derive 4 Themes clusters. In conclusion, it is necessary to create an atmosphere of respect for doctors and nurses, and each department should be able to quickly identify and deal with communication problems. Based on the research, It is suggested that the training of communication skills be strengthened to be possible.

• Journal of the Korea Convergence Society
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• v.10 no.5
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• pp.267-278
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• 2019

The objective of the current study was to engage in an in-depth discussion and analysis about the process of overcoming hardships in students that play varsity sports as student athletes and who grew up under incomplete family structures, To achieve this end, the current study conducts a narrative inquiry into the subjects, which found the following: First, in terms of improvement and expansion of interpersonal relationships, the student athletes were able to change their personalities to be more confident and active in their daily routines. Second, in forming positive emotions through playing sports, the student athletes were able to actively search for ways to overcome difficult situations and self-regulated their emotions. Third, in relation to improvement of problem-solving skills, the student athletes were able to find the most effective ways to overcome hardships caused by their broken family situations, in addition to exhibiting advanced problem-solving skills that enabled them to find courses that are most adequate for solving future problems.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.8
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• pp.1084-1094
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• 2019

Objective: The aim of this study was to select the candidate genes affecting meat quality and preliminarily explore the related molecular mechanisms in the Mashen pig. Methods: The present study explored genetic factors affecting meat quality in the Mashen pig using RNA sequencing (RNA-Seq). We sequenced the transcriptomes of 180-day-old Mashen and Large White pigs using longissimus dorsi to select differentially expressed genes (DEGs). Results: The results indicated that a total of 425 genes were differentially expressed between Mashen and Large White pigs. A gene ontology enrichment analysis revealed that DEGs were mainly enriched for biological processes associated with metabolism and muscle development, while a Kyoto encyclopedia of genes and genomes analysis showed that DEGs mainly participated in signaling pathways associated with amino acid metabolism, fatty acid metabolism, and skeletal muscle differentiation. A MCODE analysis of the protein-protein interaction network indicated that the four identified subsets of genes were mainly associated with translational initiation, skeletal muscle differentiation, amino acid metabolism, and oxidative phosphorylation pathways. Conclusion: Based on the analysis results, we selected glutamic-oxaloacetic transaminase 1, malate dehydrogenase 1, pyruvate dehydrogenase 1, pyruvate dehydrogenase kinase 4, and activator protein-1 as candidate genes affecting meat quality in pigs. A discussion of the related molecular mechanisms is provided to offer a theoretical basis for future studies on the improvement of meat quality in pigs.

• The Journal of the Korea Contents Association
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• v.21 no.10
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• pp.172-183
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• 2021

The current study delves into millennial consumers' attitude toward 'undisclosed ads' and 'disclosed ads' through in-depth interviews. More specifically, this study explores how millennial consumers think of undisclosed ads and celebrity endorsers as well as influencers through interviewing 12 millennial consumers. In addition, this study also deals with millennial consumers' attitude toward disclosed ads and celebrity endorsers as well as influencers. Study results suggest that millennial consumers perceive 'undisclosed ads' as deceiving ads and hold negative attitude toward celebrity endorsers as well as influencers who are involved in 'undisclosed ads'. Interestingly, millennial consumers hold both positive and negative attitude toward 'disclosed ads'. 'Disclosed ads' could be delivered to millennial consumers without any reservation when it is integrated as an entertaining factor into contents. On the other hands, negative feelings could occur when 'disclosed ads' is frequently employed and is forcibly embedded in contents, making millennial consumers feel that it is imperative to watch 'disclosed ads' in order to enjoy free contents. In the discussion section practical implications are provided.

• Phonetics and Speech Sciences
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• v.12 no.4
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• pp.37-45
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• 2020

This paper quantitatively calculated the speech frequency of the discourse markers 'a', 'eo', and 'eum' and the speech duration of these discourse markers using the Seoul Corpus, a spontaneous speech corpus. The sound durations were confirmed with Praat, the Seoul Corpus was analyzed with Emeditor, and the results were presented by statistical analysis with R. Based on the corpus analysis, the study investigated whether a particular factor is preferred by speakers of particular categories. The most prominent feature of the corpus is that the sound durations of female speakers were longer than those of men when using the 'eum' discourse marker in a final position. In age-related variables, teenagers uttered 'a' more than 'eo' in an initial position when compared to people in their 40s. This study is significant because it has quantitatively analyzed the discourse markers 'a', 'eo', and 'eum' by gender and age. In order to continue the discussion, more precise research should be conducted considering the context. In addition, similarities can be found in "e" and "ma" in Japanese(Watanabe & Ishi, 2000) and 'uh', 'um' in English(Gries, 2013). afterwards, a study to identify commonalities and differences can be predicted by using the cross-linguistic analysis of the discourse.

• Journal of Radiation Protection and Research
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• v.47 no.1
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• pp.8-15
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• 2022

Background: We developed a machine vision technology program that tracks patients' real-time breathing and automatically analyzes their breathing patterns. Materials and Methods: To evaluate its potential for clinical application, the image tracking performance and accuracy of the program were analyzed using a respiratory motion phantom. Changes in the stability and regularity of breathing were observed in healthy adult volunteers according to whether the breathing pattern mirrored the breathing guidance. Results and Discussion: Displacement within a few millimeters was observed in real-time with a clear resolution, and the image tracking ability was excellent. This result was consistent even in the sections where breathing patterns changed rapidly. In addition, the respiratory gating method that reflected the individual breathing patterns improved breathing stability and regularity in all volunteers. Conclusion: The findings of this study suggest that this technology can be used to set the appropriate window and the range of internal target volume by reflecting the patient's breathing pattern during radiotherapy planning. However, further studies in clinical populations are required to validate this technology.

• The Journal of the Korea Contents Association
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• v.22 no.6
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• pp.45-55
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• 2022

This study explores the issues of "eco-friendly consumption" through online media posts, and aims to identify changes in it. Total 6,812 blog posts on Naver, that included the words "eco-friendly consumption" and "eco-friendly lifestyle," published between 2005 and 2020, in five-year intervals, were analyzed. The results illustrated that consumption issues began with the identification of the causes of environmental problems however, "eco-friendly consumption" gradually gained importance, until it developed into preparing standards and alternatives for proper "eco-friendly consumption." In 2020, "eco-friendly consumption" values and ideal consumption practices were expanded into social movements. However, there is relatively little discussion on controlled and modest spending. Therefore, for the future direction of "eco-friendly consumption," it is necessary to thoroughly examine and highlight the agenda of controlled and modest living from a higher perspective.

• The Journal of the Korea Contents Association
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• v.21 no.5
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• pp.139-148
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• 2021

The study examines public attitude and reaction regarding administrative integration in Daegu and Gyeongbuk area. Specifically, it employs social big data including textual comments on online news articles and YouTube video clips. The collected data are analyzed in order to compare two periods, that is, before and after the inauguration of the Public Opinion Committee for One Daegu-Gyeongbuk. As a result, we have found that people's favorable response to administrative integration has gradually increased since the launch of the Committee. However, it still lacks specific administrative procedures and discussion topics among the frequently used words in the collected data. Thus, the Committee needs to provide a variety of information and materials related to administrative integration.

• BMB Reports
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• v.55 no.5
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• pp.205-212
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• 2022

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a debilitating chronic disorder characterized by suprapubic pain and urinary symptoms such as urgency, nocturia, and frequency. The prevalence of IC/BPS is increasing as diagnostic criteria become more comprehensive. Conventional pharmacotherapy against IC/BPS has shown suboptimal effects, and consequently, patients with end-stage IC/BPS are subjected to surgery. The novel treatment strategies should have two main functions, anti-inflammatory action and the regeneration of glycosaminoglycan and urothelium layers. Stem cell therapy has been shown to have dual functions. Mesenchymal stem cells (MSCs) are a promising therapeutic option for IC/BPS, but they come with several shortcomings, such as immune activation and tumorigenicity. MSC-derived extracellular vesicles (MSC-EVs) hold numerous therapeutic cargos and are thus a viable cell-free therapeutic option. In this review, we provide a brief overview of IC/BPS pathophysiology and limitations of the MSC-based therapies. Then we provide a detailed explanation and discussion of therapeutic applications of EVs in IC/BPS as well as the possible mechanisms. We believe our review will give an insight into the strengths and drawbacks of EV-mediated IC/BPS therapy and will provide a basis for further development.