• Toxicological Research
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• 제8권2호
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• pp.161-170
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• 1992

The objectives of this sutdy were to investigate the effects of 8-fluorociprofloxacin(8-FCP) on the central nervous system (CNS) and to compare with those of ciprofloxacin(CP). The $LD_{50}$ values of intravenous 8-FCP were similar or slightly lower in rat (M;203.6mg/kg, F;186.1mg/kg)and markedly lower in mice (M;126.5mg/kg, F;163.1mg/kg), as compared to those of CP. However, no recognizable differences in the clinical signs and recovery were found between 8-FCP and CP in both species. In combination with fenbufen, the convulsive liability of 8-FCP was higher than that of CP. At an intravenous dose of 10mg/kg, 8-FCP provoked convulsive signs and subsequent death in mice, whereas CP produced convulsion at a dose of 40mg/kg. The hexobabital -induced sleeping time was markedly lengthened by the oral administration of 8-FCP, but slightly increased by CP. In addition, the two quinolone derivatives had analgesic effects. The analgesic activity of 8-FCP was approximately two times higher than that at CP. However, both 8-FCP and CP had little effects of pentylenetetrazole-or strychnine-induced convulsion and muscle relaxation. Our finding that 8-FCP had more remarkable CNS effects than CP strongly suggests that there should be differences in the pharmacokinetic characteristics and/or in the binding affinity for specific biologic targets, or receptors, in the CNS.

• 한국학교보건학회지
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• 제6권1호
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• pp.78-92
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• 1993

The purpose of this study is to find out the stress causes of the primary students in Korea, through the three major methods, life event score, multiple regression about stress causes and G.H.Q. path-diagram. A survey was made of 889 students who were selected among students of six primary schools in seoul and Ka-pyeng, from Sep. 28 to Oct. 2. 1992. The results of this study are summarized as follows : 1. Life event score Among the children's life events, (deaths of family) (degrade of school record) (the increase of absence days) (divorce of parents) (trouble with relationship) are high ranking in life event score. Besides, (scolded by teacher and parents) (beginning of extracurricular work) are spread stress causes. In conclusion, these stress causes are shown by two aspects, home, school, and so children are under stress circumstance in both places. These stress causes vary with area and sex. 2. Multiple regression about stress causes and G.H.Q. This study analysed how a stress caused by home life affects the children's health of mind and body. The most influential factors are , and these factors vary with area and sex. 3. Path-diagram This study proved that socio-psychological school environment raises children to secede from school, and this secession that operates as a stress cause affects children's health of mind and body. This serial process is analysed by path analysis, and made out a path-diagram. In conclusion, as expected socio-psychological,school environment affects the children's health of mind and body. This is shown by two aspects : positive, negative. This stress causes vary with area and sex.

• 융합정보논문지
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• 제8권6호
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• pp.75-84
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• 2018

연구목적: 본 연구는 제2형 당뇨환자의 당화혈색소 수치 조절에 미치는 영향요인을 파악하기 위한 서술적 조사연구이다. 연구방법: 본 연구는 2015년도 1월부터 12월까지 시행된 제6기 3차 년도 국민건강영양조사 자료 중 검진조사와 건강설문조사를 이용하였으며 설문에 참여한 전체 대상자 검진조사와 건강 설문조사에 참여한 전체 대상자 7.380명 중 제2형 당뇨환자로 분류된 285명을 대상으로 진행하였다. 연구결과: 대상자의 당화혈색소 조절에 영향을 주는 요인은 연령, 교육수준, 유병기간, 수면시간으로 나타났고 나머지는 영향을 주는 요인으로 나타나지 않았다. 결론: 제2형 당뇨환자에 있어서 중년기에도 질병 이환을 발견한 시점부터 교육수준에 맞는 적절한 당뇨교육을 실시하고, 적정 수면시간을 지키도록 하는 것도 당화혈색소 수치 조절에 영향을 미치는 것으로 나타났으므로, 이에 대한 적용 가능한 교육방법이나 프로그램의 개발이 필요하다.

• 대한한방내과학회지
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• 제43권5호
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• pp.940-950
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• 2022

Objectives: The purpose of this study is to report on the efficacy of Korean medical treatment for treating menopausal vasomotor symptoms (heat flashes and sleep disorders). Methods: We treated a menopausal female patient with heat flashes and sleep disorders using Korean medical treatments (herbal medicines, acupuncture, pharmacopuncture, moxibustion, and chuna). To evaluate the results of this treatment, we used Kupperman's Index and the Numerical Rating Scale to measure heat flashes and total sleeping time, respectively. The patient's general health status was evaluated using the European Quality of Life 5 Dimensions Scale. Results: We observed improvements in Kupperman's Index, the Numerical Rating Scale, the patient's total sleeping time, and the European Quality of Life 5 Dimensions Scale following the treatments. Conclusions: This study suggests that Korean medicine may be an effective treatment for menopausal vasomotor symptoms (heat flashes and sleep disorders).

• Journal of Preventive Medicine and Public Health
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• 제55권1호
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• pp.98-105
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• 2022

Objectives: Low back pain (LBP) is a common chronic condition among sedentary workers that causes long-term productivity loss. This study aimed to identify the relationships of individual and occupational factors with LBP among Bangladeshi online professionals. Methods: We conducted a cross-sectional study involving 468 full-time online professionals who usually worked in a sitting position. One-month LBP complaints were assessed using a musculoskeletal subscale of subjective health complaints. The chi-square test was used to measure associations between categorical predictors and LBP, and multivariable logistic regression was conducted to identify the variables significantly associated with LBP. Results: LBP within the last month was reported by 65.6% of participants. Multivariable logistic regression analysis indicated that age >30 years (adjusted odds ratio [aOR], 0.40; 95% confidence interval [CI], 0.23 to 0.70) and being married (aOR, 0.59; 95% CI, 0.36 to 0.97) had significant negative associations with LBP. Significant positive associations were found for spending >50 hours weekly on average working in a sitting position (aOR, 1.61; 95% CI, 1.05 to 2.49), being overweight and obese (aOR, 1.87; 95% CI, 1.16 to 2.99), sleeping on a soft mattress (aOR, 2.01; 95% CI, 1.06 to 3.80), and ex-smoking status (aOR, 3.33; 95% CI, 1.41 to 7.87). Conclusions: A high prevalence of LBP was found among full-time online professionals. Long working hours in a sitting position showed a significant association with developing LBP. Smoking history, body mass index, and sleeping arrangements should also be considered while considering solutions for LBP prevalence among online professionals.

• 한국안광학회지
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• 제18권3호
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• pp.279-289
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• 2013

목적: 소프트 콘택트렌즈를 일시 제거한 상태에서 굴절보정을 위한 굴절검사 시의 굴절력 변화를 평가하고자 하였다. 방법: 17세에서 39세(평균 $24{\pm}4.8$세)의 소프트 렌즈 착용자 91명(남자 15명, 여자 76명 총 182안)을 대상으로 하였다. 렌즈를 제거한 뒤 즉시, 30분, 60분, 90분 후 타각적, 자각적 굴절검사 및 각막곡률반경검사를 하였다. 렌즈의 종류, 피팅 및 착용 상태별로 측정 시간에 따른 굴절력 변화를 평가하였다. 결과: 타각적, 자각적 굴절검사 및 각막곡률반경검사에서 측정 시간대별로 유의한 변화를 보였다(p<0.0001). 굴절력은 측정 초기(렌즈 제거 후 30분 후)에서 완만한 근시화 경향을, 그리고 측정 후반(렌즈 제거 후 60분에서 90분)에서 미약한 근시화 경향을 보였다. 렌즈 종류, 피팅 상태, 착용 시간, 착용 일수 및 검사 전날의 수면 시간에 따른 유의한 차이는 없었으나, 각막곡률의 변화에서 측정 시간과 렌즈 종류(p=0.017), 피팅 상태(p=0.019) 및 수면 시간(p=0.010) 간의 상호작용 효과는 유의하였다. 결론: 소프트 콘택트렌즈의 종류, 피팅 및 착용 상태와 상관없이 렌즈 제거 후 굴절력과 각막곡률의 안정화 시점은 적어도 60분 이상으로 나타났다. 따라서 굴절보정을 위한 굴절검사 시 가능한 60분 이상 기다린 후 실시하여야 할 것이다.

• 한국보건간호학회지
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• 제11권1호
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• pp.93-102
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• 1997

The study aimed at investigating the living time as well as disability degree of the elderly based on daily living acting capability and living activity degree. The survey was conducted through the home-visit interview during half month at july, 1996 by the students of nursing department who were previously trained. The survey targeted the elderly aged 65 years or more living at home in rural area. The study tried to utilize Activity Inventory(AI) made for examing health and disease, disability degree, and living acting degree of the elderly. Among the AI's, there are Physical Activity of Daily Living(PADL), Instrumental Activity of Daily Living(IADL), maximum daily activity scope, and physical and mental activity level of the elderly. The daily living time is surveyed physiologic time(sleeping, eating and grooming), labor time(occupation, housekeeping and farming) and leisure time(reading, sport hobby-life). Results of the study show that social activity degree of the elderly is found to be lower than that PADL, LADL, and daily living scope. It seems that the elderly suffer from inability in daily life with lower social activity degree. But the labour time of the daily living time is the most amount time in the targeted 361 elderlys through random sampling. Therefore postponement of the disability of aging should be devised to encourage the labour activity of the elderly.

• 한국생활과학회지
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• 제18권1호
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• pp.113-122
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• 2009

This study aimed to examine the urban families and rural families in tenns of life styles on Saturday-with-no-school. The subjects were the 386 parents whose children were in the first or second grade in rural or urban area. The instruments of analysis were time diary method and parents' stress scale developed by Kim & Kang(l997). The main results were as follows: First, in comparison with urban children, rural children spent more time in viewing TV and playing computer but spend less time in sleeping. field trip and cleaning on Saturday-with-no-school. Second, the difference of child-rearing time between mothers and fathers was less marked in urban area than in rural area. Rural fathers spent more time in watching TV or playing computer, while rural mothers spent more time in feeding and bathing of their children, helping their children do homework, and total child-rearing. Third, unlike urban parents, rural parents ddid not have much parenting stress on Saturday-with-no-school. These results show that there is a need to focus on rural parents in the preparation for introduction of 5 days-school-week system.

• 가정과삶의질연구
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• 제9권1호통권17호
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• pp.203-221
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• 1991

1) The purpose of this study is to investigate the correlation between general social changes and time budgets of younger generation in Korea. 2) I use the statistics which appeared in the 'Studies of the Time Budgets of Korean people" carried out by the Korean Broadacasting system in 1981 and in 1990. 3) The result of this analysis may be summarized as the following : (1) Even in the cases of biologically necessary acts such as sleeping and eating, the average time used by Korean younger generation is remarkably influenced by general social changes. (2) It is in the cases of optional acts such as reading, listening music and enjoying a move that general social changes influence excessively the time Budgets of children and the youth. (3) It seems that time Budgets of Korean younger generation are losing their balance and rationally year after year during 1981 and 1990. For instance they spend too much time enjoying TV or popular music. 4) As a conclusion, I shall strongly suggest : (1) Parents and school teachers should pay more attention in their guidance of their Children or pupil concerning the importnace of the time Budgest. (2) the programmers of television and radio should consider sincerly the educational influence of their products.

• 대한가정학회지
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• 제50권8호
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• pp.13-19
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• 2012

The present study explored the hours of living and playtime depending on existence of caregiver after school using the data from the Korean Children and Youth Panel Survey7071. KCYPS date collected on 1th, 4th and 7th grade children and their caregivers. The hours of living was categorized into sleeping, learning, reading and play times. Playtime was sub-categorized into time for using playing the computer/games, watching TV/DVD and playing with peer groups. The present study has shown that children in the fourth grade spent more time on learning, whereas reading children in the seventh grade spent more time on playing compared to those in other grades during the weekdays. Also, children in higher grades spent more time playing both on the weekdays and on the weekends. Students of all grades spent more time watching TV/DVD compared to other activities during the weekdays and the weekends. Children with a caregiver spent more time on learning and spent less time playing computer/game, watching TV/DVD and playing with peer groups than children without caregivers. As students moved up a grade, these results clearly appeared. Considering the results in this study, the allocation of hours of living and playtime of children altered depending on the existence of a caregivers.