• Title/Summary/Keyword: skin health

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Case Report of the Squamous Cell Carcinoma in a Patient with Oral Lichen Planus

  • Woo, Keoncheol;Oh, Duwon;Kwon, Jeong-Seung;Ahn, Hyung-Joon;Choi, Jong-hoon
    • Journal of Oral Medicine and Pain
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    • v.41 no.2
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    • pp.72-75
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    • 2016
  • Lichen planus is a chronic disease characterized by bilateral and multiple lesions on the skin or oral mucosa. Lichen planus is caused by immune mediated degeneration along the border between epithelium and connective tissue. The incidence of oral squamous cell carcinoma in patients diagnosed with oral lichen planus (OLP) is reported to be between 0.4%-5.6% in different studies and the World Health Organization has categorized lichen planus as "a potentially malignant disorder". However, the correlation between OLP and oral cancer still remains controversial as some reported that the reason for increased incidence of squamous cell carcinoma in OLP patient is misdiagnosis of dysplastic lesion as OLP. This report aims to discuss the correlation between OLP and oral cancer through a case of middle aged woman diagnosed with OLP who was successfully treated but developed squamous cell carcinoma 8 years later.

A Study on the Characteristics Analysis of Cutting Fluid Aerosol Using Dual-PDA System - for Turning Process (Dual-PDA를 이용한 절삭유 에어로졸 특성분석에 관한 연구(I) -선삭공정을 중심으로)

  • Jeong, J.Y.;Hwang, D.C.;Hong, G.B.;Woo, C.K.;Hwang, J.
    • Journal of ILASS-Korea
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    • v.10 no.2
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    • pp.10-17
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    • 2005
  • The proposed research has been performed to know the characteristics of cutting fluid aerosol formation using Dual-PDA system in machining process. The cutting fluid aerosol size and concentration is common attributes that quantify the environmental intrusiveness or air quality contamination. The atomized cutting fluid aerosols can be affected to human health risk such as lung cancer and skin irritations. Even though cutting fluid can be improved the machining quality and productivity in a carefully. its use must be controlled and optimized carefully. This experimental works using Dual-PDA were performed to analyze the cutting fluid aerosol behaviors and characteristics in turning process using precise aerosol particle measuring system. The obtained experimental results profovide basic knowledge to develop the environmentally conscious machining process. This results cail be provided as a basis to estimate and control the hazardous cutting fluid aerosol in machining process.

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Transdermal Delivery System of Effective Ingredients for Cosmeceuticals (기능성화장품을 위한 유효성분의 경피 전달 시스템)

  • Cho, Wan-Goo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.37 no.2
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    • pp.97-119
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    • 2011
  • World consumers are now focusing on their health, well-being and appearance more than ever before. This trend is creating heightened demand for products formulated as cosmeceuticals with active ingredients. A significant number of innovative formulations are now being used in cosmetics with real consumer-perceivable benefits and optimized sensory attributes, resulting in an economic uplift of cosmetic industry. To obtain skin care formulations with real consumer-perceivable benefits through dermal delivery of active ingredients, formulators are resorting to technology that until recently was used in pharmaceutical products. These various delivery systems are now being used in cosmecuetical formulations. Novel delivery systems reviewed here possess enormous potential as next-generation smarter carrier systems.

Comparing the Therapeutic Effects of Aloe vera and Olive Oil Combination Cream versus Topical Betamethasone for Atopic Dermatitis: A Randomized Double-blind Clinical Trial

  • Panahi, Yunes;Rastgar, Nassim;Zamani, Ali;Sahebkar, Amirhossein
    • Journal of Pharmacopuncture
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    • v.23 no.3
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    • pp.173-178
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    • 2020
  • Objectives: Atopic dermatitis (AD) is a prevalent and chronic, pruritic inflammatory skin condition that can influence all age groups. AD is associated with a poor health-related quality of life. This randomized clinical trial was performed to compare the effectiveness of Olivederma (combination of aloe vera and virgin olive oil) or betamethasone regarding disease severity, quality of life, serum IgE and eosinophil count. Methods: Thirty-six AD patients were randomly allocated to topical Olivederma or betamethasone, and were followed for 6 weeks. Results: Total SCORAD severity scores showed significant decrease in both groups, while it was more prominent in Olivederma group (64.5% improvement in Olivederma vs. 13.5% improvement in Betamethasone, p-value < 0.001). Quality of life (DLQI questionnaire) of AD patients was significantly improved after 6 weeks treatment with Betamethasone (22.3%, p < 0.001) and Olivederma (60.7%, p-value < 0.001). Olivederma group showed a significantly lower DLQI score in comparison with Betamethasone treated patients after 6 weeks of therapy (p < 0.001). Improvements in eosinophil count and serum IgE was observed. Conclusion: In summary, this study shows that Olivederma is superior to topical Betamethasone after 6 weeks of therapy with regard to disease severity, quality of life and eosinophil count.

Development of a Bio-Signal Measuring System Based on D-F-M (D-F-M 기반의 생체신호측정기 개발)

  • Chai, Yong-Yoong;Hong, Dong-Kwon
    • The Journal of the Korea institute of electronic communication sciences
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    • v.13 no.4
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    • pp.897-902
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    • 2018
  • The purpose of this study is to develop a bioinformatic diagnostic system that diagnoses the patient 's health condition by using the output waveform generated by applying the impulse voltage of 13Hz to 7 body parts based on DFM (Diagnose Fure Funktionelle Medizine) theory. It is expected that the data acquired by the diagnostic system will be served as a device for diagnosing the status of the body organ as well as the mesenchymal tissue through inductive reasoning based on artificial intelligence. In this paper, we will limit the system to acquire and manage bio-signals.

Aortoenteric Fistula - A Report of a Case - (대동맥장루 -1예 보고-)

  • 김성수
    • Journal of Chest Surgery
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    • v.22 no.5
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    • pp.823-828
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    • 1989
  • Aortoenteric fistula is an uncommon important complication of aortic reconstruction with a prosthetic graft. The complication often is difficult to diagnose and is associated with poor prognosis. Aortoenteric fistula could be divided into true aortoenteric fistula and paraprosthetic-enteric fistula. In case of true aortoenteric fistula, an actual communication between the gastrointestinal tract and the aortic lumen is present. So, massive gastrointestinal hemorrhage is the presenting manifestation. In paraprosthetic-enteric fistula, characterized by communication between the gastrointestinal tract and the external surface of synthetic vascular prosthesis without actual fistularization into the vascular lumen, the predominant clinical manifestation were sepsis, fever and anemia. We experienced one case of paraprosthetic-enteric fistula in a 16 years old male after abdominal aortic reconstruction with a prosthetic graft. The interval from the operation to onset of symptoms was 40 months. The initial clinical manifestation was sepsis, fever and anemia without massive gastrointestinal hemorrhage. Surgical treatment consists of complete excision of infected graft, two layers closure of jejunal wall defect and pledgets suture of aortic stump with surrounding health tissue. Anatomic revascularization was not able to be done: because of extensive retroperitoneal inflammation and extraanatomic revascularization did not performed due to adequate distal blood supply through rich collateral circulation. After operation, he complained numbness on left foot on moderate exertion and felt coldness on left leg compared with right leg but not showed skin color change. 43 days after operation, he discharged without gait disturbance except numbness on left foot on moderate exertion.

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Studies on disease of catfish(Silurus asotus) in Korea Pathology of skin ulcerous by A. hydrophila (한국산메기(Silurus asotus)의 질병에 관한 연구)

  • 한규삼;최인열;배정준;김영길;이근광;김영진
    • Korean Journal of Veterinary Service
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    • v.16 no.2
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    • pp.103-110
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    • 1993
  • The Aeromonas strains were isolated from diseased cultured catfsh (Silurus asotus) in the ponds near by Gochang of Chunbuk. The present isolates were identified as A. hydrophila based on their biological and biochemica1 characteristics. The isolates of A. hydrophila were named GC-1, GC-2, GC-3, GC-4 and GC-5, Five strains were grew optimally at temperatures $35^{\circ}C,$ pH 7.5 and in 0.5 to l% NaCl. This bacterium(GC-1) was injected into health catfish in order to prove the causative agent of ascites and haemorrhagic ulcers. The symptoms in cat fish infected by this challenge method were observed to be very similar to the symptoms of a natural infection, but controls did not show any abnormal symptoms during the experimental period. At 24 post-injection, the red spot developed around the injection site and the haemorrhagic ulcers was extended near the gill and ventral fin. Five strains were tested for drug sensitivity by plate method. All strains were sensitivity to gentamicin and resistant to penicillin, streptomycin and tetracycline.

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Effect of DHU001, a Polyherbal Formula, on Dinitrofluorobenzene-induced Contact Dermatitis (Type I allergy)

  • Lee, Hyeung-Sik;Lee, Byung-Chang;Ku, Sae-Kwang
    • Toxicological Research
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    • v.26 no.2
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    • pp.123-130
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    • 2010
  • The effect of DHU001, a mixed herbal formula consisted of 7 types aqueous extracts for various respiratory disorders were evaluated on 2,4-dinitrofluorobenzene (DNFB)-induced contact dermatitis, type I allergic model. Contact dermatitis was induced by sensitization with dinitrophenyl-derivatized ovalbumin (DNP-OVA) and DNFB challenge as antigen. Two different dosages of DHU001 (300 and 150 mg/kg) were orally administered to DNP-OVA sensitization mice once a day for 7 days with reference material, dexamethasone (15 mg/kg, intraperitoneal treatment). End of 7 days oral administration of DHU001 extracts or intraperitoneal treatment of dexamethasone, the changes on the edematous changes and scratching behavior were measured. Immediate after DNFB challenge on ear or paw of DNP-OVA sensitized mice, increases of ear and paw thicknesses and weights were detected with anterior ear skin (dermis to epidermis) thickness and paw scratching behavior increases. However, these contact dermatitis signs induced by DNFB treatment were reduced by treatment of the both different dosages of DHU001 and dexamethasone, respectively. The results obtained in this study suggest that oral treatment of DHU001 extracts also has relatively favorable effects on contact dermatitis.

Mochrus (Bombax ceiba Linn.): A Comprehensive Review on Pharmacology Phytochemistry, and Ethnomedicinal Uses

  • Fatima, Suhail;Siddiqui, Aisha;Khan, Afshan
    • CELLMED
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    • v.9 no.4
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    • pp.4.1-4.5
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    • 2019
  • The medicinal plants are extensively used for curing variegated malady in day to day life. There is an emergent demand for plant based medicines, food supplements, health products, pharmaceuticals etc. Mochrus (Bombax ceiba Linn.) is one of the valuable medicinal plants used in Unani system of medicine since relic belongs to family Bombacaceae. It is a tall tree and widely distributed through India, Africa, Australia and tropical Asia. Many parts of the plant (root, stem bark, gum, leaf, prickles, flower, fruit, seed and heartwood) are used for the treatment of a variety of ailments. It is reported to possess nafe sailanur reham (beneficial in leucorrhea), mujaffif (siccative), muqawwi reham (uterine tonic), qabiz (constipative), muallide mani (production of semen), mumsik wa mughalliz mani (increase consistency of semen), dafe fasaad khoon wa safra (purifies blood and bile) etc. It is used in asthma, diarrhoea, wound, leprosy, boils and many other skin diseases. Also possess some important pharmacological activities such as antioxidant, analgesic, antipyretic, antibacterial, diuretic, hepatoprotective, anticancer, hypoglycaemic and hypotensive etc. It is reported to contain phytoconstituents like polysaccharides, naphthoquinones, anthocyanins, lupeol and naphthol etc. This paper provides a compendium review on pharmacological, phytochemical properties and therapeutic benefits of the plant.

Study on Experience of Industrial Accidents and Awareness Level for Beauty Product Safety of Beauty Industry Employee (미용업 종사자의 사고재해 경험 및 사용제품의 안전 인식도에 관한 연구)

  • Choi, Seo-Yeon;Hur, Kuk-Kang;Park, Dong-Hyun
    • Journal of the Korea Safety Management & Science
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    • v.14 no.4
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    • pp.59-70
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    • 2012
  • This study compared data regarding industrial accidents and awareness level for beauty product safety for four main parts of beauty industry such as hair-care, nail-care, skin-care, and make-up. Major risk factors in beauty industry are dust, musculoskeletal disorders, and organic solvent of beauty product in order of percentage. The specific types of industrial accidents in beauty industry are mainly associated with musculoskeletal system such as cuts, sprain, and varicose vein. They are mainly compensated by personal budget. The awareness levels of chemical and heavy metal containment for beauty product by beauty industry employee were 77.2% and 59.1% respectively. Most employee confirmed only important items of labelling requirement of beauty product. Also, most employee did not understand MSDS(Materila Safety Data) for chemicals used in beauty industry. Only 38.1% of beauty industry employee has had safety education while most employee (73.6%) realized that they needed safety education. Also, safety education supervised by KOSHA(Korea Occupational Safety and Health Agency) was the most preferred. This study would be good basis for safe and healthy working environment of beauty industry employee.