• Korean Journal of Optics and Photonics
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• v.28 no.1
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• pp.9-15
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• 2017

We precisely measured and analyzed the dynamics of peptide-antibody interactions, using an ellipsometric biosensor based on a silicon substrate. To reduce the signal error due to the imperfect flatness of the substrate for extremely low concentrations of peptide, we fabricated the biosensor with a silicon substrate coated with Dextran SAM, instead of a glass prism coated with a thin metallic thin film. At an injection speed of $100{\mu}l/min$ of buffer liquid, we detected the dynamics of antibody-Dextran SAM or peptide-antibody fixed on biosensor, respectively. We detected the dynamics of antibody-Dextran SAM interactions down to a low concentration of 5 ng per liter, and we precisely measured the dynamics of association and dissociation of peptide and antibody down to 100 nM of peptide. We obtained the rate constants for association and dissociation from fitting the data by using deduced dynamical equation. As a result, we obtained an equilibrium constant for dissociation of 97 nM of peptide-antibody complex, which belongs to Class I.

• Korean Journal of Optics and Photonics
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• v.28 no.1
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• pp.22-27
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• 2017

Time-encoded near-infrared spectroscopy (NIRS) system is proposed, based on a near-infrared (NIR) swept laser source, for comparison to the conventional NIRS method using a detector-type spectrometer. The cavity of the NIR swept laser source consists of a semiconductor optical amplifier (SOA) with a gain region around 800 nm, and several fiber-optic components. To change the output wavelength in time using an applied electric radio-frequency signal, an acousto-optic tunable filter (AOTF) is introduced in the fiber ring cavity configuration. To demonstrate the feasibility of an NIR swept laser source for NIRS imaging, the spectroscopic comparison of two kinds of absorbance-measuring systems a detector-type spectrometer using a white light source, and a source-type spectrometer using an NIR swept laser is successfully performed with an NIR-absorbing dye.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.1
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• pp.59-67
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• 2016

A novel instrumentation amplifier (IA) using fully-differential linear operational transconductance amplifier (FLOTA) for electronic measurement systems with low cost, wideband, and gain control with wide range is designed. The IA consists of a FLOTA, two resistor, and an operational amplifier(op-amp). The principal of the operating is that the difference of two input voltages applied into FLOTA converts into two same difference currents, and then these current drive resistor of (+) terminal and feedback resistor of op-amp to obtain output voltage. To verify operating principal of the IA, we designed the FLOTA and realized the IA used commercial op-amp LF356. Simulation results show that the FLOTA has linearity error of 0.1% and offset current of 2.1uA at input dynamic range ${\pm}3.0V$. The IA had wide gain range from -20dB to 60dB by variation of only one resistor and -3dB frequency for the 60dB was 10MHz. The proposed IA also has merits without matching of external resistor and controllable offset voltage using the other resistor. The power dissipation of the IA is 105mW at supply voltage of ${\pm}5V$.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.6
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• pp.1076-1081
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• 2001

Gamma-irradiated peanuts, Korean and Chinese origins, were investigated on detection properties by thermoluminescence (TL), electron spin resonance (ESR), and DNA comet assay (single cell gel electrophoresis). TL measurement showed that the non-irradiated sample revealed a glow curve with low intensity at about 25$0^{\circ}C$, while the irradiated samples showed higher intensity around at 18$0^{\circ}C$. TL ratio (TL$_1$/TL$_2$) of area for TL$_1$ glow curve to TL$_2$ was below 0.05 for the non-irradiated sample and 0.2 or more for the irradiated ones, thus identifying each other. ESR spectroscopy for the irradiated peanuts using outer skin showed negligible signals induced by irradiation, indicating ESR is little applicable to the detection of irradiated peanuts. In DNA comet assay, the non-sample had no or very short tails, whereas the irradiated samples revealed the cells with long tails. Significance in the increase of their lengths depending on irradiation dose (r=0.761/Korean, r=0.768/Chinese) was also found. There was no remarkable difference in detection properties by origins of samples in all determinations, It is concluded that TL analysis or DNA comet assay is suitable for detection of irradiated peanuts and a combined method is recommendable for enhancing the reliability of detection results.

• Journal of Korean Society of Forest Science
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• v.89 no.3
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• pp.405-413
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• 2000

This study was conducted to develop an on-line monitoring system for a forest hydrological environment and its meteorological condition, such as temperature, wind direction and speed, rainfall and water level on V-notch, electrical conductivity(EC), potential of hydrogen(PH) by the motor drive sensor unit and measurement with a single-chip microprocessor as controller. These results are summarized as follows ; 1. The monitoring system consists of a signal process unit, motor drive sensor unit, radio modem unit and power supply. 2. The motor drive sensor unit protects the sensor from swift current or freezing and can constantly maintain fixed water level during measurements. 3. This monitoring system can transfer the data by radio modem. Additionally, this system can monitor hydrological conditions in real time. 4. The hardware was made of several modules with an independent CPU. They can be mounted, removed, repaired and added to. Their function can be changed and expanded. 5. These are the result of an accuracy test, the values of temperature, EC and pH measured within an error range of ${\pm}0.2^{\circ}C$, ${\pm}1{\mu}S$ and ${\pm}0.1pH$ respectively. 6. This monitoring system proved to be able to measure various factors for a forest hydrological environment in various experimental stations.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2015.10a
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• pp.87-90
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• 2015

Equipments that can transmit maritime distress signals in accordance to Global Maritime Distress Safety System are the followings: A1 water(Very High Frequency, SART), A2 water(MF/HF Radio Equipment), A3 water(INMARSAT), A4 water(Emergency Position Indicating Radio Beacon). Institutions with the capacity to receive distress signals are Korea Coast Guard affiliated radio stations, patrol ships, Rescue Coordination centers, Vessel Traffic centers, Complex problems regarding repetitive distress alarms, inaccurate statistics, multiple control towers are existent. Consequently, effective measurement to resolve dispersed operating maritime distress signal system are in time of need. Moreover, current KCG Headquarter is considering to integrate five distress radio stations dispersed across nation into a single international safety communication center. The integration of radio stations are efficient in terms of information coordination between nations, however, it cannot support efficient response to real-time maritime incident. Therefore, in this study, a new system that can rapidly response to real-time maritime incident will be proposed.

• Journal of the Korean Chemical Society
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• v.48 no.6
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• pp.553-560
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• 2004

In this experiment, a three dimensional structure analysis was carried out to examine the surface defects of semiconductor made artificially on known scale. It was investigated the three dimensional imaging according to the sample depth and the thermal diffusivity as well as the carrier transport properties. The thermal diffusivity measurement of the intrinsic GaAs semiconductor was also analyzed by the difference of frequency-dependence photoacoustic signals from the sample surface of different conditions. Thermal properties such as thermal diffusion length or thermal diffusivity of the Si wafer with and without defects on the surface were obtained by interpreting the frequency dependence of the PA signals. As a result, the photoacoustic signal is found to have the dependency on the shape and depth of the defects so that their structure of the defects can be analyzed. This method demonstrates the possibility of the application to the detection of the defects, cracks, and shortage of circuits on surface or sub-surface of the semiconductors and ceramic materials as a nondestructive testing(NDT) and a nondestructive evaluation(NDE) technique.

• Investigative Magnetic Resonance Imaging
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• v.2 no.1
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• pp.67-72
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• 1998

The mapping of the spin-spin relaxation time T2 in pixel-by-pixel was suggested as a quantitative diagnostic tool in medicine. although the CPMG pulse sequence has been known to be the best pulse sequence for T2 measurement in physics NMR, the supplied pulse sequence by the manufacture of MRI system was able to obtain the maximum of 4 CPMG images. Eight or more images with different echo time TEs are required to construct a reliable T2 map, so that two or more acquisitions were required, which easily took more than 10 minutes. 4-echo CPMG imaging pulse sequence was modified to generate the maximum of 8 MR images with evenly spaced echo time TEs. In human MR imaging, since patients tend to move at least several pixels between the different acquisitions, 8-echo CPMG imaging sequence reduces the acquisition time and may remove any mis-regitration of each pixels signal for the fitting of T2. The resultant T2 maps using the theoretically simulated images and using the MR images of the human brain suggested that 8 echo CPMG sequence with short echo spacing such as 17-20 msec can give the reliable T2 map.

• Investigative Magnetic Resonance Imaging
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• v.7 no.2
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• pp.108-115
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• 2003

Purpose : To evaluate the effect of the gradient switching noise on the ECD source localization with the EEG data recorded during the MRI scan. Materials and Methods : We have fabricated a spherical EEG phantom that emulates a human head on which multiple electrodes are attached. Inside the phantom, electric current dipole(ECD) sources are located to evaluate the source localization error. The EEG phantom was placed in the center of the whole-body 3.0 Tesla MRI magnet, and a sinusoidal current was fed to the ECD sources. With an MRI-compatible EEG measurement system, we recorded the multi channel electric potential signals during gradient echo single-shot EPI scans. To evaluate the effect of the gradient switching noise on the ECD source localization, we controlled the gradient noise level by changing the FOV of the EPI scan. With the measured potential signals, we have performed the ECD source localization. Results : The source localization error depends on the gradient switching noise level and the ECD source position. The gradient switching noise has much bigger negative effects on the source localization than the Gaussian noise. We have found that the ECD source localization works reasonably when the gradient switching noise power is smaller than $10\%$ of the EEG signal power. Conclusion : We think that the results of the present study can be used as a guideline to determine the degree of gradient switching noise suppression in EEG when the EEG data are to be used to enhance the performance of fMRI.

• Journal of the Korea Society of Computer and Information
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• v.16 no.5
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• pp.61-71
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• 2011

To measure the fatigue of metallic objects at high speed vibration while non-contact precision displacement measurement on how to have a lot of research conducted. Noncontact high-speed vibration detection sensor of the eddy current sensors and laser sensors are used, but it is very expensive. Recently, High-speed vibrations detection using an inexpensive inductive sensor to have been studied, but is still a beginner. In this paper, a new design of an inexpensive inductive proximity sensor has been suggested in order to measure high frequency dynamic displacements of metallic specimens in a noncontact manner. Detection of the existing inductive sensors, detection, integral, and amplified through a process to detect the displacement noise due to weak nature of analog circuits and integral factor in the process of displacement detection is slow. The proposed method could be less affected by noise, the analog receive and high-speed signal processing is a new way, because AD converter (Analog to Digital converter) without using the vibration frequency signals directly into digital signals are converted. In order to evaluate the sensing performance, The proposed sensor module using non-contact vibration signals were detected while shaker vibration frequencies from 30Hz to 1,100 Hz at intervals of vibrating metallic specimens. Experimental results, Vibration frequency detection range of the metallic specimins within close proximity to contactless 5mm could be measured from DC to 1,100Hz and vibration amplitude of the resolution was $20{\mu}m$. Therefore, the proposed non-contact inductive sensor module for precision vibration detection sensor is estimated to have sufficient performance.