• 제목/요약/키워드: sign and symptom

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Alimentary Tract Duplication in Pediatric Patients: Its Distinct Clinical Features and Managements

  • Kim, Soo-Hong;Cho, Yong-Hoon;Kim, Hae-Young
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제23권5호
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    • pp.423-429
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    • 2020
  • Purpose: Alimentary tract duplication (ATD) is a rare congenital condition that may occur throughout the intestinal tract. Clinical symptoms are generally related to the involved site, size of duplication, or associated ectopic mucosa. This study aimed to identify clinical implications by anatomical locations and age group and then suggest a relevant management according to its distinct features. Methods: We retrospectively reviewed the clinical data of pediatric patients who received a surgical management due to ATD. Furthermore, data including patients' demographics, anatomical distribution of the duplication, clinical features according to anatomical variants, and outcomes were compared. Results: A total of 25 patients were included in this study. ATD developed most commonly in the midgut, especially at the ileocecal region. The most common clinical presentation was abdominal pain, a sign resulting from intestinal obstruction, gastrointestinal bleeding, and intussusception. The non-communicating cystic type was the most common pathological feature in all age groups. Clinically, prenatal detection was relatively low; however, it usually manifested before the infantile period. A laparoscopic procedure was performed in most cases (18/25, 72.0%), significantly in the midgut lesion (p=0.012). Conclusion: ATD occurs most commonly at the ileocecal region, and a symptomatic one may usually be detected before the early childhood period. Surgical management should be considered whether symptom or not regarding its symptomatic progression, and a minimal invasive procedure is the preferred method, especially for the midgut lesion.

대동맥류의 수술적 치료에 관한 임상적 연구 (Clinical Study of Surgical Treatment of Aortic Aneurysm)

  • 류지윤;전홍주;조광현
    • Journal of Chest Surgery
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    • 제30권3호
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    • pp.300-307
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    • 1997
  • 인제대학교 부속 부산백병 원 흉부외과학교실에서는 지난 87년 10월부터 96년 1월까지 총25례의 흉부 및 복부 대동맥류를 수술로 치험하였다. 환자의 연령은 최소 26세에서 최고 73세(평균연령 52. 5세)였으며 남자가 13명 여자가 12명이였다. 발생 부위에 따라흉부 대동맥류가 18례 복부 대동맥류가7례였다. 원인에 따른 분류에서 16례가 박리성이 였으며 9례가 비박리성 대동맥류였다. 동맥류의 위험 인자로는 고혈압이 가장 많았으며 기타 고지질증, Marfan증후군등이였다. 흉부 대동맥류는 침범 부위에 따라 동맥류 절제술과 인조혈관 대치술 및 관상동맥 이식술등을 증례에 따라적절히 시행하였다. 복부 대동맥류는 동맥류 절제후 침범 부위에 따라 일자 또는 역Y형 인조혈관 을 대 치시켰다. 총 5례의 술후 사망이 있어서 수술 사망률은 20%였으며 생존 환자는 특별한 합병증 없이 퇴원하였다.

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치매 한의 평가도구 개발을 위한 기초 연구 (Preliminary Study to Develop the Instrument of Oriental Medical Evaluation for dementia)

  • 류창희;정인철;조성훈;황의완;강위창;이상룡
    • 동의신경정신과학회지
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    • 제21권4호
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    • pp.123-135
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    • 2010
  • Objectives : This study was performed to develop a standard instrument of oriental medical evaluation for dementia. Methods: The advisor committee on this study was organized by 17 neuropsychiatry professors of oriental medical colleges. The items and structure of the instrument were based on review of published literature. We took consultation twice from the advisor committee and we also took additional advices bye-mail. Results: We discriminated between bian-zheng and su-zheng from the answers of the advisor committee. We got the mean weight of each symptom and sign from the answers of the advisor committee. We got the final weight from the combination of the ratio of bian-zheng to the number of all answers of the advisor committee and mean weight. Conclusions : The instrument of oriental medical evaluation for dementia was developed through experts' discussion. If the validity and reliability of this instrument is confirmed through additional clinical trial. the instrument of oriental medical evaluation for dementia is expected to be applied to the subsequent research.

관상동맥 회로술 치험 1예 (Aorto-Coronary Bypass Graft -A Case Report-)

  • 이두연
    • Journal of Chest Surgery
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    • 제12권3호
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    • pp.297-305
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    • 1979
  • Occlusive coronary artery disease presents a potential threat to a significant population in the United States. According to many case reports, the increasing incidence of coronary artery disease due to atherosclerosis is noted in Korean, recently. Operative vascular procedures have increased steadily in number over the past 20 years in the United States. There have been many isolated case reports about coronary artery surgery, but these had little clinical impact. Nowadays, major three coronary bypass surgery has developed principally at three cardiac centers in the United States since 1967. Among three coronary bypass operation, the aorta-coronary artery saphenous vein bypass graft was first demonstrated by Favolaro and Effler at the Cleveland Clinic in 1967. We experienced one case of coronary artery disease, which was treated successfully by aorta-coronary saphenous vein graft with mild hypothermia under extracorporeal circulation in May, 1977. Saphenous vein was removed from above the knee and was 2.5 mm in diameter. The left ventricle was not vented for the left ventricle was not overdistended. Temporary artificial pace-maker-Medtronic-was implanted for the prevention and treatment of post-operative arrhythmia and heart block in post-operative first day. He is a 57 year old male businessman who had been suffered from hypertension [200 mmHg in systolic pressure] since 4 years ago, who had intermittent conservative treatment at local clinic. He had been afflicted with severe chest pain with choking sensation for 50 days. This symptom was aggravated exposing cold weather, or cold water, but was respond to rest. Pre-operative ECG revealed no any other ischemic sign except sinus bradycardia. Significant S-T segment depression was noted at lead II, AVF after double 5 minutes exercise, indicating positive Master`s test. Serum cholesterol was slight elevated to 253 mg/dl. Final pre-operative diagnosis was made by coronary arteriogram, which showed about 1.0-cm segmental 90 % occlusive atherosclerotic lesion in the proximal part of right coronary artery above the origin of acute marginal artery. Left coronary artery revealed good patency and there was no collateral circulation between right and left coronary artery .Hospital course was not eventful. He was discharged with good result on the post-operative day. He has been free from chest pain for longer than 2 years. And also the arterial flow in the coronary bypass graft is auscultated with the pocket-sized ultrasonic velocity detector, which shows the patency of the coronary bypass graft good.

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EFFICACY OF HAMῡL OF MARHAME DAKHILYUN AND ROGHANE SAUSAN IN CERVICITIS (ILTIHAB-E-UNUQ-UL- REHAM)- AN OPEN OBSERVATIONAL CLINICAL STUDY

  • HUMA;PROF WAJEEHA BEGUM;KOUSER FATHIMA FIRDOSE
    • 셀메드
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    • 제13권6호
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    • pp.4.1-4.10
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    • 2023
  • Background and objective: Cervicitis are an inflammatory condition of the cervix. This may be acute, chronic, active & specific or non-specific, which may cause various sign & symptoms. Abnormal vaginal discharge, lower abdominal pain, lower backache, post coital bleeding. If not treated timely it causes various complications viz PID, infertility, endometritis, ectopic pregnancy etc. Hence it has been decided to conduct a clinical trial for its management. Method: This study was an open observational study. The entire patients were allocated by considering the criteria of inclusion & exclusion. Marhame dakhilyun with roghane sausan is given 10 mg as ḥamūl at bed time, after menses for 21 days. All the patients were assessed by primary outcome of abnormal vaginal discharge, lower abdominal pain, lower backache, post coital bleeding & secondary outcomes of vaginal symptoms scale score (VSS) which score the vaginal discharge with QOL in cervicitis patients and vaginal analogue scale (VAS) for pain. Result: In this present study, marked improvement is observed in cervicitis. The mean ± SD of vaginal discharge before & after treatment is 2.57±0.050, 0.33±0.48 respectively which is highly significant with p value of<0.0001**. VSS score before & after treatment is 21.27±6.12, 7.47±2.48 respectively with p<0.0001** which is highly significant. VAS score used for LAB & LPA before & after treatment is 6.63±1.09, 1.90±1.29 respectively with p<0.0001** which is highly significant. Interpretation & Conclusion: The study revealed that the formulation has been found effective in healing congestion, hypertrophied of the cervix and discharge and relieving the others associated symptoms of cervicitis. It is useful and provided immediate and effective treatment for cervicitis. Hence, the trial drug can be recommended for its management.

안면마비로 초기 발현된 소아 급성골수성백혈병: 조혈모세포이식으로 성공적으로 치료한 3예 (Facial palsy as the presenting symptom of acute myeloid leukemia in children: Three cases with stem cell transplantations)

  • 백희조;한동균;김영옥;최익선;황태주;국훈
    • Clinical and Experimental Pediatrics
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    • 제52권6호
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    • pp.713-716
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    • 2009
  • 안면 마비가 백혈병의 최초증상으로 발현되는 경우는 매우 드물고, 이들 대부분은 두개내 방사선 치료를 받는다. 이에 저자들을 백혈병의 최초증상으로 안면마비가 발현된 3례의 환자들을 보고하고자 한다. 3례 모두 두개내 방사선 치료없이 관해유도가 된 후 조혈모세포이식을 시행하였다. 2례는 동종이식 후 각각 52개월, 62개월까지 무사건 생존 중이고, 나머지 1례는 자가이식 후 재발의 최초증상으로 안면마비가 나타났고, 타인 조혈모세포이식 후 59개월째 무사건 생존 중이다. 2례에서 여전히 안면마비가 남아있긴 하지만, 두개내 방사선 치료 없이도 동종 조혈모세포이식으로 안면마비가 발현된 백혈병을 치료하여 이를 보고하고자 한다.

폐암 한의 평가도구 개발 기초 연구 (Preliminary Study to Develop the Instrument of Oriental Medical Evaluation for Lung Cancer)

  • 박소정;김선영;조종관;정인철;유화승
    • 대한한의학회지
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    • 제36권3호
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    • pp.53-64
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    • 2015
  • Objectives: The aim of study was to develop a standard instrument of oriental medical evaluation lung cancer. Methods: For this study, the committee advisor was organized by 10 Korean Medicine professors of the Korean Association of Traditional Oncology. The items and structure of the instrument were quoted from the instrument of pattern identification for lung cancer. We had a consultation with the committee twice and took additional advice from it via E-mail. Results: According to the research, we determined the Korean oriental medical assessment tool for lung cancer comprised of the 6 types of patterns of syndrome differentiation. The advisor committee gave the answers about discrimination between bian-zheng and su-zheng, mean weight of each symptom and sign. The final weight was calculated from the combination of the ratio of bian-zheng and mean weight. Conclusions: The instrument of oriental medical evaluation for lung cancer was developed through experts' discussion. If the validity and the reliability of this instrument are validated through additional clinical trial, the instrument of oriental medical evaluation for lung cancer is expected to be applied to the later research.

시지각적 요소를 갖춘 건축물 위험징후 측정 모니터링 시스템 설치 가이드라인 개발연구 (Developing the Installation Guideline of Building Monitoring Systems for Hazardous Symptom Measurements with Visual Perception)

  • 김희재;김근영;신정재
    • 한국재난정보학회 논문집
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    • 제16권2호
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    • pp.374-382
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    • 2020
  • 연구목적: 최근 노후한 안전관리 미비 시설물의 구조적 결함으로 인한 건축물 및 시설물 붕괴사고 등이 발생하고 있다. 본 연구는 전시 공간 건축물의 위험징후를 분석하고 계측기술을 개발하기 위해 시지각적 요소를 갖춘 건축물 센서 모니터링을 위한 최적의 센서 위치를 결정하는 상시 모니터링 시스템 설치가이드라인을 개발하는 것을 목적으로 한다. 연구방법: 위험징후 계측 기기의 구성요소, 설치위치, 기기의 경보 기준, 관리 방안 등을 제시한다. 연구결과: 센서의 위치를 결정하고, 통일된 시지각을 갖춤으로서 분석을 위한 신호처리 기술을 확보하고, Test-bed 운영 통해서 센서 모니터링 기반의 최적 '위험징후 감지장치'를 구성하는 방안을 제시하였다. 결론: 본 연구의 결과는 전시 공간 건축물 붕괴로 발생할 수 있는 재난으로부터 대비하고, 안전관리 역량을 강화에 기여할 수 있다.

$^{99m}Tc$-MDP 골 스캔 중 발견된 위 및 장관의 섭취증가 7예 (7 Cases of Incidental Radionuclide Uptake in the Gabtrointestinal Tract During $^{99m}Tc$-Methylene Diphosphonate Bone Scintigraphy)

  • 손태용;김형건;유영진;이상구;천은미;임상무;홍성운
    • 대한핵의학회지
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    • 제27권2호
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    • pp.315-318
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    • 1993
  • We experienced 7 cases of patients who were performed $^{99m}Tc$-methylene diphosphonate bone scintigraphy for the evaluation of diseases they had. Their bone scintigrams showed incidental radionuclide uptake in the gastrointestinal tracts and they had no special symptom or sign attributable to the findings. Case 1 showed radionuclide uptake in the stomach and both lung and the patient had suffered from hypercalcemia and azotemia. Case 3 and case 6 showed diffuse radionuclide uptake in the stomach and intestinal tract. Others showed diffuse or regional radionuclide uptake in the intestinal tracts. Radionuclide uptake in the gastrointestinal tract by $^{99m}Tc$-methylene diphosphonate is caused by a certain pathologic lesion but also can be seen in the normal gastrointestinal tract. So, one who reads bone scintigrams should be alert for the pathologic lesion in the gastrointestinal tract although one must interpretate with the concept of this normal variations.

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추간판내 Prostaglandin E2 양의 임상적 의의 (Clinical Implication of Prostaglandin E2 Content in Lumbar Disc Disease)

  • 김형석;조기홍;김기용;안영환;안영민;윤수한;조경기
    • Journal of Korean Neurosurgical Society
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    • 제29권10호
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    • pp.1340-1344
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    • 2000
  • Objective : A prospective biochemical assay of prostaglandin $E_2$ content in symptomatic lumbar disc materials was done in order to clarify the pathogenesis of lumbar radiculopathy. Patients and Methods : Forty-eight disc specimens were purified by a standard solid-phase extraction procedure and analyzed by an enzymelinked immunosorbent assay for prostaglandin $E_2$. Clinical and anatomic correlations were evaluated with analysis of variance and t-test. Results : Acute herniated lumbar disc diseases tended to be associated with a higher prostaglandin $E_2$ content than degenerative lumbar disc disease. Sequestered discs tended to be associated with a higher prostaglandin $E_2$ content than extruded discs, which also showed higher prostaglandin $E_2$ content than protruded ones. A sciatica and positive straight leg raising test appeared to be associated with a higher prostaglandin $E_2$ content than a negative test. Conclusion : This result suggests that the level of prostaglandin $E_2$ would be correlated with clinical symptom and sign in the inflammatory process of lumbar disc herniation.

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