CELLMED (셀메드)

Cellmed Orthocellular Medicine and Pharmaceutical Association (셀메드 세포교정의약학회)
권호 표지
DOI QR코드

DOI QR Code

EFFICACY OF HAMῡL OF MARHAME DAKHILYUN AND ROGHANE SAUSAN IN CERVICITIS (ILTIHAB-E-UNUQ-UL- REHAM)- AN OPEN OBSERVATIONAL CLINICAL STUDY

  • Received : 2022.10.06
  • Accepted : 2023.05.31
  • Published : 2023.05.31
Download PDF
⟨ Previous Next ⟩

Abstract

Background and objective: Cervicitis are an inflammatory condition of the cervix. This may be acute, chronic, active & specific or non-specific, which may cause various sign & symptoms. Abnormal vaginal discharge, lower abdominal pain, lower backache, post coital bleeding. If not treated timely it causes various complications viz PID, infertility, endometritis, ectopic pregnancy etc. Hence it has been decided to conduct a clinical trial for its management. Method: This study was an open observational study. The entire patients were allocated by considering the criteria of inclusion & exclusion. Marhame dakhilyun with roghane sausan is given 10 mg as ḥamūl at bed time, after menses for 21 days. All the patients were assessed by primary outcome of abnormal vaginal discharge, lower abdominal pain, lower backache, post coital bleeding & secondary outcomes of vaginal symptoms scale score (VSS) which score the vaginal discharge with QOL in cervicitis patients and vaginal analogue scale (VAS) for pain. Result: In this present study, marked improvement is observed in cervicitis. The mean ± SD of vaginal discharge before & after treatment is 2.57±0.050, 0.33±0.48 respectively which is highly significant with p value of<0.0001**. VSS score before & after treatment is 21.27±6.12, 7.47±2.48 respectively with p<0.0001** which is highly significant. VAS score used for LAB & LPA before & after treatment is 6.63±1.09, 1.90±1.29 respectively with p<0.0001** which is highly significant. Interpretation & Conclusion: The study revealed that the formulation has been found effective in healing congestion, hypertrophied of the cervix and discharge and relieving the others associated symptoms of cervicitis. It is useful and provided immediate and effective treatment for cervicitis. Hence, the trial drug can be recommended for its management.

Keywords

References

  1. Bhirud, A. & Bendale, T. J. I. M. J. S. Prevalence of cervicitis and outcome: A hospital based study. 2, 502-504 (2015).
  2. Li, M. et al. Prevalence and risk factors for bacterial vaginosis and cervicitis among 511 female workers attending gynecological examination in Changchun, China. 58, 385-389 (2019).
  3. Edwards, J. L. & Apicella, M. A. J. C. m. r. The molecular mechanisms used by Neisseria gonorrhoeae to initiate infection differ between men and women. 17, 965-981 (2004).
  4. Kumar, P. & Malhotra, N. Jeffcoate's principles of gynaecology. (Jaypee Brothers Medical Pub., 2008).
  5. Sheeder, J., Stevens-Simon, C., Lezotte, D., Glazner, J. & Scott, S. J. J. o. a. h. Cervicitis: to treat or not to treat? The role of patient preferences and decision analysis. 39, 887-892 (2006).
  6. Lusk, M. J. et al. Cervicitis: a prospective observational study of empiric azithromycin treatment in women with cervicitis and non-specific cervicitis. 28, 120-126 (2017). https://doi.org/10.1177/0956462416628319
  7. ABZ, R. New Delhi : CCRUM Al-Hawi Fil tib vol. IX, 9-37 (2001).
  8. HM, A. k. 2011. New Delhi: Aijaz publishing House Al Akseer.vol II 781-784.
  9. Majoosi. New Delhi: Idarae Kitabul Shifa Tarjuma Kamil Sana. Vol. III (Urdu trans by Kantoori GH), 492-493 (2010).
  10. National Formulary of Unani Medicine. Part Ist, 162 (2006).
  11. National Formulary of Unani Medicine. Part IV, 109 (2006).
  12. CCRUM New Delhi Physicochemical Standards of Unani Formulation. Vol 3rd, 125 (1991).
  13. Marrazzo, J. M. et al. Risk factors for cervicitis among women with bacterial vaginosis. 193, 617-624 (2006). https://doi.org/10.1086/500149
  14. ابوالحسنی ,بهار ,عامری, Clinical, م. J. J. o. & Research, B. Prevalence and risk factors of cervicitis in married women in Shahroud, northeast of Iran. 2, 20-25 (2018).
  15. Ansari S, B. W., Firdose KF. Efficacy of Unani Formulation in Cer vical Ectopy (Quruhal Rahim))-An Open Observational Study. Int J Cur Res Rev 13, 31 (2021).
  16. Lateef Unnisa, M., Alam, A. & Naveed, W. Efficacy of Unani Formulation in the Management of Chronic Cervicitis-A Prospective Observational Study.
  17. Shazamani, S., Begum, W. & Sumaiya, S. J. P. R. Effect of Althea officinalis Linnaeus (Tuqme khatmi) in Cervicitis (Iltehabe unqur rehm)-An Open Observational Clinical Study. 14 (2022).
  18. Hashmi, S., Begum, W. & Sultana, A. J. E. J. o. I. M. Efficacy of Sphaeranthus indicus and cream of Lawsonia inermis in cervical erosion with cervicitis. 3, e183-e188 (2011). https://doi.org/10.1016/j.eujim.2011.08.002
  19. Fahamiya, N., Shiffa, M., Aslam, M., Farzana, M. J. J. o. P. & Phytochemistry. Unani perspective of Khatmi (Althaea officinalis). 5, 357-360 (2016).
  20. GM, N. Khazainul mufridat wa murakkabat Central Council Pharm Research New Delhi, 39-235.
  21. DHN, T. A. Taj ul- Mufridat: Idarae kitab-us- Shifa New Delhi, 5-59,346-391,581-591,709-717. (2010).
  22. Prajapati ND, K. U. Agro's Dictionary of Medicinal Plants. Jodhpur: Agrobio (India), 21-96,172-355 (2005).
  23. Musthasan D, A. D. Advia Madniya 101 (2004).
  24. MH, K. Ilmul ul-advia Nafeesi New Delhi : Aijaz Publication House, p.92-100-182,239-338 (2007).
  25. Bagdadi MA, A. M. f. T. CCRUM New Delhi, 190 (2005).