• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1991년도 가을 학술발표회 논문집
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• pp.87-92
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• 1991

It was achieved to formulate numerically the stress-strain relationship of concrete, which is a fundamemtal factor for the Elasto-Plastic analysis of concrete structures, for normal concrete by using random statistics. As a result of experiment, in the shape of stress-strain curves of normal concrete it has approach linear from first loading to peak point, and after that point deformation increased radically and specimens were brokendown abruptly. From the multiple linear regression, and obtained the exponential equaion for stress-strain relationship of concrete as follows: $\sigma$/$\sigma$max=e(1-$\varepsilon$/$\varepsilon$max)$\varepsilon$/$\varepsilon$max

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 하계학술대회 논문집 B
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• pp.1250-1252
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• 2003

This Paper presents Sigma-Delta Modulation(SDM) schemes to generate switching waveform for a high-power factor boost-type rectifier. The SDM scheme can be implemented by simple digital algorithm unlike conventional PWM schemes with several hardware, and has the characteristics of spectrum-spreading and noise-shaping effects, which are profitable in harmonic reduction of input current in the boost-type rectifier. The comparison results of their spectrum performances shows that the 1st-order SDM has better harmonic suppression effect than conventional PWM scheme and Dithered SDM scheme.

• Applied Biological Chemistry
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• 제35권1호
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• pp.14-22
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• 1992

일련의 새로운 N-[1-(benzotriazol-1-yl)-X-치환-aryl]-Y-치환-arylamine 유도체를 합성하고 Pyricularia oryzae, Fusarium oxysporum f. sp. sesami, Valsa ceratosperma 및 Botrytis cinerea에 대한 항균활성$(pI_{50})$을 한천 희석법으로 측정하여 정량적인 구조-활성 관계$(QSAR_S)$를 분석한 바, X 및 Y-치환기들의 ${\pi}$와 ${\sigma}$ 및 $M_R$ 파라미터가 항균 활성을 결정하는 중요한 요소이었다. 4-bromo 치환체(1d 및 2b)가 항균활성이 제일 큰 화합물이었으며, 중성 pH에서 1의 가수분해 반응에 대한 반감기$(T_{1/2})$는 약 1.5일 이었다. 기질 화합물의 분자궤도(MO) 함수와 항균 반응에 대한 자유에너지 관계$(LFER_S)$ 그리고 분자 설계의 결과들이 검토되었다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 춘계학술대회논문집A
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• pp.165-169
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• 2000

A simple method was suggested to calculate the stress intensity factor for a one-sided patched crack with finite thickness. To consider out-of-plane bending effect resulting from the load-path eccentricity, the spring constant as a function of the through-thickness coordinate z was calculated from the stress distribution in the un-cracked plate, ${\sigma}_{yy}(y=0,\;z)$, and the displacement for the representative single strip Joint, $u_y(y=0,\;z)$. The stress Intensity factors were obtained using Rose's asymptotic solution approach and compared with the finite element results. In short crack region, two results had a little difference. However, two results were almost same in long crack region. On the other hand, the stress intensity factor using plane stress assumption was more similar to finite element result than plane strain condition.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2000년도 추계학술대회논문집 - 한국공작기계학회
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• pp.434-439
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• 2000

In this paper, in order to study the geometric factor effect of a circular hole near a crack tip in a semi-infinite plate, the Dimensionless Stress Intensity Factor, $F(=\frac K {\sigma {\sqrt{\pi a}}})$ is analyzed at the crack tip using a two Dimensional Boundary Element Method (BEM) program which is known as superior in Fracture Mechanics. Kelvin's solution was used as a fundamental solution in BEM analysis and displacement extrapolation method was used to determine Stress Intensity Factor.

• 품질경영학회지
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• 제44권3호
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• pp.639-648
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• 2016

Purpose: Existing precedent studies include success factors of individual management innovation activities constantly. However, those studies have limitations about the common key success factors of individual management innovation activities. Methods: For this study, we investigate the key success factors using literature research of the most typical management innovation activities adopted and implemented by many companies in Korea, such as 6sigma, TQM, Lean 6sigma, ERP, TPM, BPR, Project Management, System Engineering. Factors emerging repeatedly was combined into common factors and inherent factors that are necessary for the success of individual management innovation activities are designated to essential factors. Results: 'Essential factors for Six Sigma' consist of 5 items. Black belt operating system, personnel management system linkage, the correct management of the data, perform improvement projects associated with financial performance financial result, linked to financial performance improvement project, project progress management. 'Essential factors of TQM' are arranged 4 items. Quality team's independence and role, goal-setting, Quality Information System, corporate's philosophy of quality first. 'Essential factors of Lean Six Sigma' are the selection of value stream which is based on the customer needs and the value creation and identify the project based on the selected value in the company. 'Essential factors of ERP' are investigated 6 items. Ongoing system maintenance and upgrades, the measurement and support of user satisfaction, the operating systems and the policies for the maintenance, IT infrastructure, change adaption condition monitoring, focusing on improving business performance. 'Essential factors for TPM' are arranged 4 items. Motivated and energetic Bottom-Up, CEO's recognition of the importance facility management, long-term perspective of necessity and ongoing patience. 'Essential factors for BPR' are the pursuit of change process and the staff's sense of crisis management. 'Essential factors for Project Management' are the strategy that reduce the risk management skills through risk management and the understanding and organized management for the project participant's needs. 'Essential factors for System Engineering' consist of 2 items. The first is the design for the best balanced system with pre-analysis about the compromise the cost, schedule and the performance. The second is the analysis of large problem into small problems which can solved. We have found the solution considering components of the interface through the systematic perspective. Conclusion: Common factors and essential factors presented in this study will properly help to introduce the individual management innovation activities for the each business sector and implement management innovation. After this study, new literature research that reflect new studies should accomplish steadily.

• 한국어병학회지
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• 제30권2호
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• pp.79-88
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• 2017

현재 양식장에서는 Aeromonad를 비롯한 다양한 병원균에 의한 전염병으로 인해 많은 경제적 손실을 겪고 있다. 연어과 어류뿐만 아니라 담수 및 해수어류에도 치명적인 감염을 야기하는 Aeromonas 종은 적어도 26종 이상이 보고되어왔으며, 전염병을 유발하는 유비쿼터스 세균이다. Aeromonas 종을 확인하기 위해 16S rDNA 및 하우스 키핑 유전자의 핵산 서열을 기반으로 한 분자생물학적 기술이 사용될 수 있다. 본 연구에서 Aeromonas 종은 강원도 16개 양식장의 연어과 어류로부터 분리되었으며 Aeromonad의 16S rDNA와 하우스 키핑 유전자의 서열, 즉 RNA polymerase sigma factor ${\sigma}^{70}$ (rpoD) 또는 DNA gyrase subunit B (gyrB)를 기반으로 계통 발생 학적으로 동정했다. 그 결과 대서양 연어 (Salmo salar), 은연어 (Oncorhynchus keta), 산천어 (Oncorhynchus masou masou), 무지개송어 (Oncorhynchus mykiss)에서 96 개의 균주가 수집되었으며, 36개의 균주가 16S rDNA 분석에 의해 Aeromonas 속으로 확인되었다. 확인된 Aeromonas 속 균주는 rpoD 또는 gyrB 유전자 서열을 기반으로 추가 분석되어 Aeromonas salmonicida (24 균주), A. sobria (10 균주), A. media (1 균주) 및 A. popoffii (1 균주)로 검출되었으며, 이 것은 Aeromonas salmonicida가 강원도의 연어과 어류에서 주요 감염균임을 나타낸다. 또 하우스 키핑 유전자의 서열에 기초한 Aeromonas 종의 계통발생학적 동정은 16S rDNA 서열보다 더 정확하다는 것이 또한 증명되었다.

• Clinical and Experimental Reproductive Medicine
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• 제29권2호
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• pp.117-127
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• 2002

Objective: This study was to investigate the generation of the functional neuron derived from human embryonic stem (hES, MB03) cells on in vitro neural cell differentiation system. Methods: For neural progenitor cell formation derived from hES cells, we produced embryoid bodies (EB: for 5 days, without mitogen) from hES cells and then neurospheres (for $7{\sim}10$ days, 20 ng/ml of bFGF added N2 medium) from EB. And then finally for the differentiation into mature neuron, neural progenitor cells were cultured in i) N2 medium only (without bFGF), ii) N2 supplemented with 20 ng/ml platelet derived growth factor-bb (PDGF-bb) or iii) N2 supplemented with 5 ng/ml brain derived neurotrophic factor (BDNF) for 2 weeks. Identification of neural cell differentiation was carried out by immunocytochemistry using $\beta_{III}$-tubulin (1:250), MAP-2 (1:100) and GFAP (1:500). Also, generation of functional neuron was identified using anti-glutamate (Sigma, 1:1000), anti-GABA (Sigma, 1:1000), anti-serotonin (Sigma, 1:1000) and anti-tyrosine hydroxylase (Sigma, 1:1000). Results: In vitro neural cell differentiation, neurotrophic factors (PDGF and BDNF) treated cell groups were high expressed MAP-2 and GFAP than non-treated cell group. The highest expression pattern of MAP-2 and $\beta_{III}$-tubulin was indicated in BDNF treated group. Also, in the presence of PDGF-bb or BDNF, most of the neural cells derived from hES cells were differentiated into glutamate and GABA neuron in vitro. Furthermore, we confirmed that there were a few serotonin and tyrosine hydroxylase positive neuron in the same culture environment. Conclusion: This results suggested that the generation of functional neuron derived from hES cells was increased by addition of neurotrophic factors such as PDGF-bb or BDNF in b-FGF induced neural cell differentiation system and especially glutamate and GABA neurons were mainly produced in the system.

• Corrosion Science and Technology
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• 제6권3호
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• pp.103-111
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• 2007

The effect of stress factors on the growing process of stress corrosion cracking (SCC) of the sensitized 18-8 stainless steel in high temperature water was investigated using equations of crack growth rate derived from applying electric circuits to SCC corrosion paths. Three kinds of cross sections have to be considered when electric circuit is constructed using total current. The first is ion flow passage area, $S_{sol}$, of solution in crack, the second is total dissolving surface area, $S_{dis}$, of metal on electrode of crack tip and the third is dissolving cross section, $S_{met}$, of metal on grain boundary or in base metal or in welding metal. Stress may affect each area. $S_{sol}$ may depend on applied stress, $\sigma_{\infty}$, related with crack depth. $S_{dis}$ is expressed using a factor of $\varepsilon(K)$ and may depend on stress intensity factor, K only. SCC crack growth rate is ordinarily estimated using a variable of K only as stress factor. However it may be expected that SCC crack growth rate depends on both applied stress $\sigma_{\infty}$ and K or both crack depth and K from this consideration.$\varepsilon(K)$ is expressed as ${\varepsilon}(K)=h_2{\cdot}K^2+h_3{\cdot}K^3$ when $h_{2}$ and $h_{3}$ are coefficients. Also, relationships between SCC crack growth rate, da/dt and K were simulated and compared with the literature data of JBWR-VIP-04, NRC NUREG-0313 Rev.2 and SKIFS Draft. It was pointed out in CT test that the difference of distance between a point of application of force and the end of starter notch (starting point of fatigue crack) may be important to estimate SCC crack growth rate. An anode dissolution current density was quantitatively evaluated using a derived equation.

• 한국해양공학회지
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• 제9권1호
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• pp.92-100
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• 1995

The effect of different anisotropy and stress ratio on fatigue crack propagation behavior was investigated under various stress ratio(R=-0.4, -0.2, 0.2, 0.2, 0.4) using pure titanium sheet used in aerospace, chemical and food industry. The rack closure behavior under constant load amplitude fatigue crack propagation test was examined. Fatigue crack propagation rate da/dN was estimated in terms of effective stress intensity factor range, $\Delta$K$_{eff}$, regardless of various stress ratio but was influenced by anisotropy. Also, it was found that the effect of anisotropy was considerably decreased but still not negligible when he da/dN was evaluated by a conventional parameter, $\Delta$$K_{eff}$/E and when the modified da/dN.$\sqrt{\varepsilon}_f$ was evaluated by $\Delta$$K_{eff}$/E. On the other hand, da/dN could be evaluated uniquely by effective new parameter, $\Delta$K$_{eff}$/$sigma_{ys}$, regardless of anisotropy, as int he following equation da/dN=C''[\frac{{\Delta}K_{eff}}{{\sigma}_{ys}}]^{n''}. And effective stress intensity factor range ratio, U was estimated by the following equation with respect to the ratio of reversed plastic zone size, $\Delta r_{p}$ to monotonic plastic zone size, $r_p$ regardless of stress ratio and anisotropy. U=-4.45$(\Delta r_{p}/r_{p})^{2}$+4.1$(\Delta r_{p}/r_{p})$+0.245_{p})$+0.245