• Bulletin of the Korean Chemical Society
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• v.24 no.5
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• pp.593-599
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• 2003

The nanoparticle magnetite of which diameter was about 3 nm was synthesized in a homogeneous aqueous solution without a template. The synthesized magnetite nanoparticle was easily oxidized to maghemite in an ambient condition. The magnetic properties of the ferrite nanoparticle show superparamagnetism at room temperature and its blocking temperature is around 93 K. Modifying the sequential adsorption method of metal bisphosphonate, we have prepared a multilayer thin film of the ferrite nanoparticle on planar substrates such as glass, quartz and Si wafer. In this multilayer the ferrite nanoparticle layer and an alkylbisphosphonate layer are alternately placed on the substrates by simple immersion in the solutions of the ferrite nanoparticle and 1, 10-decanediylbis (phosphonic acid) (DBPA), alternately. This is the first example, as far as we know, of nanoparticle/alkyl-bisphosphonate multilayer which is an analogy of metal bisphosphonate multilayer. UV-visible absorption and infrared reflection-absorption studies show that the growth of each layer is very systematic and the film is considerably optically transparent to visible light of 400-700 nm. Atomic force microscopic images of the film show that the surface morphology of the film follows that of the substrate in μm-scale image and the nanoparticle-terminated surface is differentiated from the DBPA-terminated one in nm-scale image. The magnetic properties of this ferrite/DBPA thin film are almost the same as those of the ferrite nanoparticle powder only.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1995.04a
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• pp.136-143
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• 1995

The problem of the structural identification becomes important, particularly with relation to the rapid increase of the number of the damaged or deteriorated structures, such as highway bridges, buildings, and industrial facilities. This paper summarizes the recent studies related to those problems by the present authors. The system identfication methods are generally classified as the time domain and the frequency domain methods. As time doamin methods, the sequential algorithms such as the extended Kalman filter and the sequential prediction error method are studied. Several techniques for improving the convergences are incorporated. As frequency domain methods, a new frequency response function estimator is introduced. For damage estimation of existing structures, the modal perturbation and the sensitivity matrix methods are studied. From the example analysis, it has been found that the combined utilization of the measurement data for the static response and the dynamic (modal) properties are very effictive for the damage estimation.

• The Korean Journal of Applied Statistics
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• v.9 no.2
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• pp.95-108
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• 1996

There are many clinical trials where a large portion of the patients are cured of disease. In such a case, one might be more interested in testing the differences in cure rates rather than other types of differences in failure distribution. For ethical and economic reasons, clinical trials must be repeatedly monitored for evidence of treatment benefit or harm. In this article, we examined by simulation the properties of nonparametric group sequential methods for comparing the cure rates between two treatment groups during the trial in a wide range of alternatives, censoring rates and cure rates.

• Proceedings of the Korean Society of Computational and Applied Mathematics Conference
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• 2003.09a
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• pp.14-14
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• 2003

Given a sequence ｛ $X_{n}$｝ of independent and identically distributed random variables with F, a sequential procedure for the p-th quantile ξ$_{P}$= $F^{-1}$ (P), 0$\beta$-protection. Some asymptotic properties for the proposed procedure and of an involved stopping time are proved: asymptotic consistency, asymptotic efficiency and asymptotic normality. From one of the results an effect of smoothing based on kernel functions is discussed. The results are also extended to the contaminated case.e.e.

• The Korean Journal of Food And Nutrition
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• v.9 no.3
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• pp.294-298
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• 1996

By the 505 chromotest which utilized Escherichia bolt PQ 37, Korean medicinal plants had been screened to Investigate the antimutagenic effect to aflatoxin B1(AFBl). Ikmocho(IMC, Leonurus sibiricus L.) was extracted with hot water. The extract was not found to be mutagenic in the Salmonella mutation test with or without metabolic activation, and the extract was showed to possess the antimutagenic properties towards AFB1-induced metation. The mutagenicity of AFB1 was inhibited by methanol soluble fracstion (IMC-MS) in dose-dependent. However, water-soluble fraction exhibited comutagenic activity. The greatest inhibitory effect of IMC-MS on AFB1 mutagenicity occurred when IMC-MS was first incubated, AFB1 followed by a second incubation with the cells and 59 mixture. Also lower inhibition was occurred when S9 mixtures were first incubated, with IMC-MS followed by a second incubation with AFBI. The results of the sequential incubation study support the probability that one mechanism of inhibition could involve the formation of chemical complex between IMC-MS and AFB1 rather than deactivation of S9 enzyme.

• Journal of the Korean Data and Information Science Society
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• v.14 no.3
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• pp.673-685
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• 2003

In this paper we consider the problem of identifying and testing outliers in linear regression. First we consider the problem for testing the null hypothesis of no outliers. A test based on the ratio of two residual scale estimates is proposed. We show the asymptotic distribution of the test statistics by Monte Carlo simulation and investigate its properties. Next we consider the problem of identifying the outliers. A forward sequential procedure using the suggested test is proposed and shown to perform fairly well. Unlike other forward procedures, the present one is unaffected by masking and swamping effects because the test statistic is based on robust scale estimate.

• Journal of Korea Technical Association of The Pulp and Paper Industry
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• v.34 no.3
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• pp.38-45
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• 2002

The effect of sequential oxidative-reductive bleaching on brightening of the MOWs is investigated. The improvement in brightnesses of MOWs is more effective in conventional PFAS bleaching than in P/T bleaching. There is no difference in the mechanical properties or the bleached pulps between PFAS and P/T sequences. Considering the brightness gains and bleaching chemicals cost, for the MOW A(Initial brightness: 68.3% ISO) containing 5％ ONP and 20% colored paper, the P/T bleaching is more economical than the PFAS bleaching. However for MOW B(initial brightness: 59.1％ ISO) containing 15% ONP and 35％ colored paper, there is no difference in the bleaching efficiency between PFAS and P/T bleaching.

• Magazine of the Korean Society of Agricultural Engineers
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• v.18 no.4
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• pp.4232-4241
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• 1976

This study was carried out to clarify the stochastic characteristics of monthly rainfalls and to select a proper model for generating the sequential monthly rainfall amounts. The results abtained are as follows: 1. Log-Normal distribution function is the best fit theoretical distribution function to the empirical distribution of monthly rainfall amounts. 2. Seasonal and random components are found to exist in the time series of monthly rainfall amounts and non-stationarity is shown from the correlograms. 3. The Monte Carlo model shows a tendency to underestimate the mean values and standard deviations of monthly rainfall amounts. 4. The 1st order Markov model reproduces means, standard deviations, and coefficient of skewness with an error of ten percent or less. 5. A correlogram derived from the data generated by 1st order Markov model shows the charaterstics of historical data exactly. 6. It is concluded that the 1st order Markov model is superior to the Monte Carlo model in their reproducing ability of stochastic properties of monthly rainfall amounts.

• Proceedings of the Korea Concrete Institute Conference
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• 1997.10a
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• pp.627-632
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• 1997

Recently, the prestressed concrete box girder bridges are increasingly built at various locations in the world. The mechanical and structural behavior of prestressed concrete brides varies because of time-dependent material properties and sequential change of structural system due to stepwise construction. The time-dependent behavior of concrete is of importance in the design and construction of segmentally constructed and cast-in-place prestressed concrete box girder bridges. The structural response is affected b variations in creep, shrinkage properties of concrete. In this study, the example of time-dependent deformations is extended to establish how the variability in concrete properties affects the accuracy of the calculated deformations in such a bridge, and finally the results are discussed.

• The Korean Journal of Applied Statistics
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• v.26 no.4
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• pp.581-594
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• 2013

A group sequential design can end a clinical trial early if a confirmed efficacy or a futility of study medication is found during clinical trials. Adaptation can adjust the design of clinical trials based on accumulated data. The key to this methodology is considered to control the overall type 1 error rate while maintaining the integrity of clinical trials. The estimation would be more complex and the sample size calculation will be more difficult if the clinical trials have repeated measurement data. Lee et al. (2002) suggested a repeated observation case by using the independent increments properties of the interim test statistics and investigated the properties of the proposed confidence interval based on the stage-wise ordering. This study extend Lee et al. (2002) to adaptive group sequential design. We suggest test statistics for the adaptation as redesigning the second stage of clinical trials and induce the stage-wise confidence interval of parameter of interests. The simulation will help to confirm the suggested method.