• Biomolecules & Therapeutics
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• v.24 no.6
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• pp.572-580
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• 2016

3-Deoxysappanchalcone (3-DSC) has been reported to possess anti-allergic, antiviral, anti-inflammatory and antioxidant activities. In the present study, we investigated the effects of 3-DSC on the proliferation of human hair follicle dermal papilla cells (HDPCs) and mouse hair growth in vivo. A real-time cell analyzer system, luciferase assay, Western blot and real-time polymerase chain reaction (PCR) were employed to measure the biochemical changes occurring in HDPCs in response to 3-DSC treatment. The effect of 3-DSC on hair growth in C57BL/6 mice was also examined. 3-DSC promoted the proliferation of HDPCs, similar to Tofacitinib, an inhibitor of janus-activated kinase (JAK). 3-DSC promoted phosphorylation of ${\beta}$-catenin and transcriptional activation of the T-cell factor. In addition, 3-DSC potentiated interleukin-6 (IL-6)-induced phosphorylation and subsequent transactivation of signal transducer and activator of transcription-3 (STAT3), thereby increasing the expression of cyclin-dependent kinase-4 (Cdk4), fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF). On the contrary, 3-DSC attenuated STAT6 mRNA expression and IL4-induced STAT6 phosphorylation in HDPCs. Finally, we observed that topical application of 3-DSC promoted the anagen phase of hair growth in C57BL/6 mice. 3-DSC stimulates hair growth possibly by inducing proliferation of follicular dermal papilla cells via modulation of $WNT/{\beta}$-catenin and STAT signaling.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.07a
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• pp.327-330
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• 2023

본 연구의 목적은 노인의 정보화기기 활용 능력이 사회자본 형성에 미치는 영향을 분석하고 이러한 관계에서 노인의 디지털기기 이용 효능감이 갖는 매개효과를 검증하는 데 있다. 이를 위해 2022년 실시한 디지털정보격차 실태조사 자료를 활용하여 SPSS 25.0 통계프로그램으로 개인의 인구사회학적특성, 정보화기기 중 PC, 모바일 기기 활용능력, 디지털기기 이용 효능감을 독립변수로 하고 노인의 사회자본을 종속변수로 하여 영향 관계를 분석하였다. 또한, 디지털기기 이용 효능감을 매개변수로 설정하여 노인의 정보화기기 활용 능력이 사회자본 형성에 미치는 영향에 매개효과가 있는지 검증하였다. 그 결과, 노인의 사회자본 형성에 미치는 영향 요인은 남성보다 여성의 사회자본 수준이 높았고, 나이가 많은 사람, 월평균 소득이 높은 사람, 다른 가족과 함께 거주하는 노인의 사회자본 수준이 높은 것으로 분석되었다. 독립변수인 PC활용능력은 통계적으로 유의미한 영향이 없었고, 모바일기기 활용 능력과 디지털기기 이용 효능감이 높을수록 사회자본이 증가하는 것으로 분석되었다. 이후 노인의 정보화기기 활용 능력이 사회자본에 미치는 영향을 디지털기기 이용 효능감이 매개하는지 분석하기 위해 Baron과 Kenny(1986)의 3단계 모형으로 분석한 결과, pc활용능력 → 디지털기기 이용 효능감 → 사회자본에 이르는 경로와 모바일기기 활용능력 → 디지털기기 이용 효능감 → 사회자본에 이르는 매개효과 경로는 통계적으로 유의미한 결과로 나타났다. 이러한 연구결과를 바탕으로 노인의 정보화기기의 접근성 향상을 위한 교육기관의 노력과 단순한 컨텐츠 위주의 교육에서 보다 실용적이고 즉시적인 교육 콘텐츠 전환 등 실천적 노력에 대해 제언하였다.

• (The)Study of the Eastern Classic
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• no.48
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• pp.41-63
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• 2012

This research paper is aims to study the Zhu Xi school of Neo-Confucianism culture based on the Sosu seowon. Also This research paper is to discuss study and scholars correlation the Sosu seowon. The Sosu seowon is mainly made up of the Zhu Xi school of Neo-Confucianism development. The Sosu seowon was the cradle of scholars and bureaucrats. Scholars who study of orthodox Neo-Confucianism in the our country was respected academic spirit of An Whyang in the study of orthodox Neo-Confucianism. An Whyang is symbolic existence of the Sosu seowon. He knew well the importance of learning. He was the person to represent the Sosu seowon. Toegye and Sinje are handed down to the fundamental principle brought in on the orthodox Neo-Confucianism caused by An Whyang. This research paper is to based upon on academic spirit of An Whyang in the study of orthodox Neo-Confucianism. Scholars who study of orthodox Neo-Confucianism thought that the nation's happiness made appointment to a competent person learned the orthodox Neo-Confucianism caused by An Whyang related to the Humanism education.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.05a
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• pp.137-138
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• 2022

1. 생체 인증만을 이용하여 인증절차를 구성하여 장점을 극대화 한다. 2. 사용자를 인증하는 새로운 인증 방법을 고안하고, 융합 할 수 있다.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.31 no.2
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• pp.128-135
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• 2013

The purpose of this study is a suggestion that it is a way for conservation and management the Namgye Seowon's heritage value based on its landscape visibility and land use; Namgye Seowon is a world heritage registration object. To do this, We had done a field investigation and a literature examination. The investigations are as following; first, setting protection zone through a comprehensive approach beyond uniform cultural properties protection zone is to note current intellectual situations as well as the place related to the locational characteristics and figures of Namgye Seowon. It's to set fore seeable section of landscape by analyzing visibility focusing through on Pungyeongnu, and it consider with protection zone and the present condition of land use. Especially, external view of landscape in Namgye Seowon is visualized with Baekam-san in the distance view of it and Cheonhwang-bong in Daebong-san and nearby large soundproof walls and the towers acts as an impediment factor to the view of landscape. In addition, to recover the original view of landscape of the Namgye Seowon, reckless plans focusing the authenticity of the world heritage should be limited and in case of the vegetation landscape, restoration and maintenance will be made through historical research literature. Through this study, researches on Namgye Seowon and several seowons will be done actively and its aims are to become the framework of landscape conservation and management measures to meet world heritage criteria.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.01a
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• pp.195-197
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• 2023

본 연구의 목적은 청년 대학 졸업자 취업 성공 요인 분석과 수도권과 비수도권의 결정 요인 비교를 통해 대학의 취업 지원을 전략과 방향을 제시하는 것이다. 이를 위해 2019년 대졸자 취업경로이동조사 자료를 활용하여 개인특성, 학교특성, 진로선택 및 취업프로그램 참여, 취업 준비 활동 경험을 독립변수로 하고 취업 성공 여부를 종속변수로 하여 취업 성공 요인을 분석하였다. 그 결과, 서울·수도권 대졸자는 개인특성 중 연령, 부모자산, 어학연수 경험이 취업 성공(+) 요인이었고, 대학특성은 2~3년제 대졸자가 4년제, 교육대 대졸자 보다 취업성공 가능성이 높았다. 진로선택 및 취업프로그램 참여 중 직장체험, 면접·이력서 작성이 취업 성공(+)요인으로 직업심리검사는 취업 성공(-) 요인으로 나타났다. 취업준비활동 경험 중 SSAT 자격증, 공모전 수상, 대외활동, 이력서·면접훈련은 취업 성공(+) 요인으로 졸업 전 구직활동, NCS 준비, 외모관리는 취업 성공(-)요인으로 나타났다. 반면, 비수도권 대졸자는 개인특성 중 연령, 부모자산이 취업 성공(+)요인이었고, 2~3년제 대졸자가 4년제, 교육대 대졸자 보다 취업성공 가능성이 높았다. 진로선택 및 취업프로그램 참여 중 직장체험, 면접·이력서 작성이 취업 성공(+)요인으로, 직업심리검사, 기업채용설명회는 취업 성공(-)요인으로 나타났다. 취업준비활동 경험 중 봉사활동, 공모전 수상, 대외활동, 모의면접은 취업 성공(+)요인이었고, 졸업 전 구직활동, 자격증, 외모관리는 취업 성공(-)요인이었다. 이를 바탕으로 4년제 대학의 비교과 활동 강화, 취업환경과 유사한 실무능력 배양 교육, 면접·이력서 작성 등 실제적 취업지도 프로그램 시행을 제시하였고, 봉사활동, 대외서포터즈, 공모전 등 취업처에 실무능력을 보여줄 수 있는 실무활동 참여를 지원하는 방안 등을 제시하였다.

• Journal of architectural history
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• v.12 no.3
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• pp.117-130
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• 2003

Transparency orginated from a visual character of the object recognized to the backside without any obstacle is used as a word explaining the variety of an architectural character from the pre-mordern architecture. Transparency is expressed clearly without using of the material with a permeability like glass in the Korean traditional architecture. Thus the purpose of this study is to analyze an expression of the perceptive transparency focusing on the Dodong Seowon with the phenomenal transparency. In chapter one, the background, purpose and method of study are explained. In chapter two, general concept of transparency is inquired. In the process of searching for the formation of basic background, the characteristic of phenomenal transparency is recognized. In chapter three, the aspect of phenomenal tranparency expression in Korean traditional architecture is inquired. In chapter four, with the characteristics drawn from chapter three, the characteristics of Dodong-Seowon under its phenomenal tranparency are shown. In chapter five, synthetic conclusion is presented.

• Korean Journal of Human Ecology
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• v.5 no.1
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• pp.65-73
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• 1996

The purpose of this study was to investigate preference in clothing fashion design and clothing purchase behavior. The questionnaires were administered to 281 female university students in Cheongju area to measure of demographic information, preference in clothing fashion design, interest of fashion in clothing, and clothing purchase behavior. As statistical analysis, frequencies, $x^2$-test and ANOVA were used. The results were as follows : 1. There were different preference in clothing fashion design. 2. The female university students had moderate interest of fashion in clothing, and the interest of fashion in clothing were significantly different according to personal factors. 3. The female university students purchased mainly their clothings at department store, and they were purchased on sale. 4. Most of female university students purchased T-shirts and pants from February to April, 1995.

• Korean Journal of Human Ecology
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• v.5 no.1
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• pp.99-111
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• 1996

The purpose of this study is to find some directions to enhance high school students' recognitions for the necessity of Home Economics(HE) education. 309 respondents were sampled from boys', girls' and co-ed high schools in Chongju. The questionnaire consisted of some items about the respondents' interest, necessity, and the required level for HE. The results are as follows : 1) Students from girls' high school and co-ed high school showed more interest in HE than did the students from boys' high school. 2) The recognition of the necessity for learning HE in high school was significantly differed according to the school systems. 3) The demand level on HE was 52.8 out of 100 point, which is fairly low. Girls from co-ed high school showed higher demand on HE than did the girls' high school. 4) The highest demand level of students in the detailed domains of HE was on consumption. And the students showed a comparatively high demand on health, job, and consumption, while showing low demand on clothing. 5) Students from boys' high school and co-ed high school favored practice-oriented HE education.

• Journal of the Korean Society of Industry Convergence
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• v.11 no.3
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• pp.141-148
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• 2008

Most of the recent studies on Seowon have been done just in terms of classification of general kinds of building layout, so there are a few things ignored such as the way they were arranged, the compositional process of buildings etc.. Although the classification of types itself is meaningful in the study on Korean traditional architecture, there has been some limitation in deep analysis of each style. The aim of this study is to find out the characteristics of the building layout and space composition of Dodong-Seowon with the viewpoint of the process of changes of it during the time through the survey and analysis on both the existing site layout and the measuring unite of scale applied to the original construction of each building. Hierarchical order scheme was considered in the design of the space proceeding from the entrance to the main space and of the building position, axis and the roof heights of buildings.