3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling |
Kim, Young Eun
(Cosmecutical R&D Center, HP&C, Seowon University)
Choi, Hyung Chul (Cosmecutical R&D Center, HP&C, Seowon University) Lee, In-Chul (Department of Cosmetic Science & Engineering, Seowon University) Yuk, Dong Yeon (Cosmecutical R&D Center, HP&C, Seowon University) Lee, Hyosung (Department of Pharmaceutical Science & Engineering, Seowon University) Choi, Bu Young (Department of Pharmaceutical Science & Engineering, Seowon University) |
1 | Kang, B. M., Shin, S. H., Kwack, M. H., Shin, H., Oh, J. W., Kim, J., Moon, C., Moon, C., Kim, J. C., Kim, M. K. and Sung, Y. K. (2010) Erythropoietin promotes hair shaft growth in cultured human hair follicles and modulates hair growth in mice. J. Dermatol. Sci. 59, 86-90. DOI |
2 | Ke, N., Wang, X., Xu, X. and Abassi, Y. A. (2011) The xCELLigence system for real-time and label-free monitoring of cell viability. Methods Mol. Biol. 740, 33-43. DOI |
3 | Kim, J. H., Choo, Y. Y., Tae, N., Min, B. S. and Lee, J. H. (2014) The anti-inflammatory effect of 3-deoxysappanchalcone is mediated by inducing heme oxygenase-1 via activating the AKT/mTOR pathway in murine macrophages. Int. Immunopharmacol. 22, 420-426. DOI |
4 | Kishimoto, J., Burgeson, R. E. and Morgan, B. A. (2000) Wnt signaling maintains the hair-inducing activity of the dermal papilla. Genes Dev. 14, 1181-1185. |
5 | Kitagawa, T., Matsuda, K., Inui, S., Takenaka, H., Katoh, N., Itami, S., Kishimoto, S. and Kawata, M. (2009) Keratinocyte growth inhibition through the modification of Wnt signaling by androgen in balding dermal papilla cells. J. Clin. Endocrinol. Metab. 94, 1288-1294. DOI |
6 | Kotanides, H. and Reich, N. C. (1996) Interleukin-4-induced STAT6 recognizes and activates a target site in the promoter of the interleukin-4 receptor gene. J. Biol. Chem. 271, 25555-25561. DOI |
7 | Lin, K. K., Chudova, D., Hatfield, G. W., Smyth, P. and Andersen, B. (2004) Identification of hair cycle-associated genes from time-course gene expression profile data by using replicate variance. Proc. Natl. Acad. Sci. U.S.A. 101, 15955-15960. DOI |
8 | Liu, A. L., Shu, S. H., Qin, H. L., Lee, S. M., Wang, Y. T. and Du, G. H. (2009) In vitro anti-influenza viral activities of constituents from Caesalpinia sappan. Planta Med. 75, 337-339. DOI |
9 | Oshima, H., Rochat, A., Kedzia, C., Kobayashi, K. and Barrandon, Y. (2001) Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell 104, 233-245. DOI |
10 | Millar, S. E., Willert, K., Salinas, P. C., Roelink, H., Nusse, R., Sussman, D. J. and Barsh, G. S. (1999) WNT signaling in the control of hair growth and structure. Dev. Biol. 207, 133-149. DOI |
11 | Paus, R. and Cotsarelis, G. (1999) The biology of hair follicles. N. Engl. J. Med. 341, 491-497. DOI |
12 | Plikus, M. V., Mayer, J. A., de la Cruz, D., Baker, R. E., Maini, P. K., Maxson, R. and Chuong, C. M. (2008) Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature 451, 340-344. DOI |
13 | Price, F. D., von Maltzahn, J., Bentzinger, C. F., Dumont, N. A., Yin, H., Chang, N. C., Wilson, D. H., Frenette, J. and Rudnicki, M. A. (2014) Inhibition of JAK-STAT signaling stimulates adult satellite cell function. Nat. Med. 20, 1174-1181. DOI |
14 | Reddy, S., Andl, T., Bagasra, A., Lu, M. M., Epstein, D. J., Morrisey, E. E. and Millar, S. E. (2001) Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech. Dev. 107, 69-82. DOI |
15 | Sano, S., Kira, M., Takagi, S., Yoshikawa, K., Takeda, J. and Itami, S. (2000) Two distinct signaling pathways in hair cycle induction: Stat3-dependent and -independent pathways. Proc. Natl. Acad. Sci. U.S.A. 97, 13824-13829. DOI |
16 | Wang, Z., Li, G., Tse, W. and Bunting, K. D. (2009) Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement. Blood 113, 4856-4865. DOI |
17 | Shen, J., Zhang, H., Lin, H., Su, H., Xing, D. and Du, L. (2007) Brazilein protects the brain against focal cerebral ischemia reperfusion injury correlating to inflammatory response suppression. Eur. J. Pharmacol. 558, 88-95. DOI |
18 | Soma, T., Fujiwara, S., Shirakata, Y., Hashimoto, K. and Kishimoto, J. (2012) Hair-inducing ability of human dermal papilla cells cultured under Wnt/-catenin signalling activation. Exp. Dermatol. 21, 307-309. DOI |
19 | Stenn, K. S. and Paus, R. (2001) Controls of hair follicle cycling. Physiol. Rev. 81, 449-494. DOI |
20 | Tsai, S. Y., Sennett, R., Rezza, A., Clavel, C., Grisanti, L., Zemla, R., Najam, S. and Rendl, M. (2014) Wnt/-catenin signaling in dermal condensates is required for hair follicle formation. Dev. Biol. 385, 179-188. DOI |
21 | Xing, L., Dai, Z., Jabbari, A., Cerise, J. E., Higgins, C. A., Gong, W., de Jong, A., Harel, S., DeStefano, G. M., Rothman, L., Singh, P., Petukhova, L., Mackay-Wiggan, J., Christiano, A. M. and Clynes, R. (2014) Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition. Nat. Med. 20, 1043-1049. DOI |
22 | Yang, F., Zhou, W. L., Liu, A. L., Qin, H. L., Lee, S. M., Wang, Y. T. and Du, G. H. (2012) The protective effect of 3-deoxysappanchalcone on in vitro influenza virus-induced apoptosis and inflammation. Planta Med. 78, 968-973. DOI |
23 | Cotsarelis, G. (1997) The hair follicle: dying for attention. Am. J. Pathol. 151, 1505-1509. |
24 | Yodsaoue, O., Cheenpracha, S., Karalai, C., Ponglimanont, C. and Tewtrakul, S. (2009) Anti-allergic activity of principles from the roots and heartwood of Caesalpinia sappan on antigen-induced -hexosaminidase release. Phytother. Res. 23, 1028-1031. DOI |
25 | Youn, U. J., Nam, K. W., Kim, H. S., Choi, G., Jeong, W. S., Lee, M. Y. and Chae, S. (2011) 3-Deoxysappanchalcone inhibits tumor necrosis factor--induced matrix metalloproteinase-9 expression in human keratinocytes through activated protein-1 inhibition and nuclear factor-kappa B DNA binding activity. Biol. Pharm. Bull. 34, 890-893. DOI |
26 | Yu, B. D., Mukhopadhyay, A. and Wong, C. (2008) Skin and hair: models for exploring organ regeneration. Hum. Mol. Genet. 17, R54-R59. DOI |
27 | Zeidler, C., von Kockritz, A., Luger, T. A., Stander, S., Husstedt, I. W. and Tsianakas, A. (2016) Tofacitinib, a novel JAK3 inhibitor, as a potential cause of distal symmetric polyneuropathy. J. Eur. Acad. Dermatol. Venereol. 30, 1066-1067. DOI |
28 | Paus, R. and Foitzik, K. (2004) In search of the "hair cycle clock": aguided tour. Differentiation 72, 489-511. DOI |
29 | Andl, T., Reddy, S. T., Gaddapara, T. and Millar, S. E. (2002) WNT signals are required for the initiation of hair follicle development. Dev. Cell 2, 643-653. DOI |
30 | Botchkarev, V. A. and Kishimoto, J. (2003) Molecular control of epithelial-mesenchymal interactions during hair follicle cycling. J. Investig. Dermatol. Symp. Proc. 8, 46-55. |
31 | Goldstein, J., Fletcher, S., Roth, E., Wu, C., Chun, A. and Horsley, V. (2014) Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation. Genes Dev. 28, 983-994. DOI |
32 | Cotsarelis, G. and Millar, S. E. (2001) Towards a molecular understanding of hair loss and its treatment. Trends Mol. Med. 7, 293-301. DOI |
33 | Cotsarelis, G., Sun, T. T. and Lavker, R. M. (1990) Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61, 1329-1337. DOI |
34 | Doles, J., Storer, M., Cozzuto, L., Roma, G. and Keyes, W. M. (2012) Age-associated inflammation inhibits epidermal stem cell function. Genes Dev. 26, 2144-2153. DOI |
35 | Festa, E., Fretz, J., Berry, R., Schmidt, B., Rodeheffer, M., Horowitz, M. and Horsley, V. (2011) Adipocyte lineage cells contribute to the skin stem cell niche to drive hair cycling. Cell 146, 761-771. DOI |
36 | Gat, U., DasGupta, R., Degenstein, L. and Fuchs, E. (1998) De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated -catenin in skin. Cell 95, 605-614. DOI |
37 | Hardy, M. H. (1992) The secret life of the hair follicle. Trends Genet. 8, 55-61. DOI |
38 | Harel, S., Higgins, C. A., Cerise, J. E., Dai, Z., Chen, J. C., Clynes, R. and Christiano, A. M. (2015) Pharmacologic inhibition of JAK-STAT signaling promotes hair growth. Sci. Adv. 1, e1500973. DOI |
39 | Huelsken, J., Vogel, R., Erdmann, B., Cotsarelis, G. and Birchmeier, W. (2001) -Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105, 533-545. DOI |
40 | Jahoda, C. A. and Christiano, A. M. (2011) Niche crosstalk: intercellular signals at the hair follicle. Cell 146, 678-681. DOI |