• Maxillofacial Plastic and Reconstructive Surgery
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• 제18권4호
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• pp.652-672
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• 1996

Dysfunction of the inferior alveolar nerve may result from trauma, diseases or iatrogenic injury. The development and refinement of an objective method to evaluate this clinical problem is highly desirable and needed, especially concerning for an increasing medico-legal issue. Evoked potential techniques have attracted considerable attention as a means of assessing the function and integrity of nerve pathways. The purpose of this study was to characterize the Sensory Evoked Potentials(SEPs) and Somatosensory Evoked Potentials(SSEPs) elicited by electrical stimulation of mental nerve. SEPs and SSEPs were measured and analyzed statistically before and after needle injury on the inferior alveolar nerve of Sprague-Dawalye rats. Measuring SEPs was more sensitive in evaluation of the recovery of sensory function from inferior alveolar nerve injury then measuring SSEPs but we measured SSEPs in the hope of providing a safe, simple and objective test to check oral and facial sensibility, which is acceptable to the patient. We stimulated mental nerve after needle injury on the inferior alveolar nerve and SEPS on the level of mandibular foramen and SSEPs on the level of cerebral cortex were recorded. Threshold, amplitude, and latency of both of SEPs and SSEPs were analyzed. The results were as follows ; 1. Threshold of SEPs and SSEPs were $184{\pm}14{\mu}A$ and $164{\pm}14{\mu}A$ respectively. 2 SEPs were composed of 2 waves, i.e., N1 N2 in which N1 was conducted by II fibers and N2 was conducted by III fibers. 3. SSEPS were composed of 5 waves, of which N1 and N2 shower statistically significant changes(p<0.01, unpaired t-test). 4. SEPs and SSEPs were observed to be abolished immediately after local anesthesia and recovered 30 minutes later. 5. SEPs were abolished immediately after injury. N1 of SSEPs was abolished immediately and amplitued of N2 was decreased($20.7{\pm}12.2%$) immediately after 23G needle injury, but N3, N4 and N5 did not change significantly. Recovery of waveform delayed 30 minutes in SEPs and 45 minutes in SSEPs. 6. The degree of decrease in amplitude of SEPs and SSEPs, after 30G needle injury was smaller than those with 23G. SEPs recorded on the level of mandibular foramen were though to be reliable and useful in the assessment of the function of the inferior alveolar nerve after injury. Amplitude of SSEPs reflected the function and integrity of nerve and measuring them provided a safe, simple and abjective test to check oral and facial sensibility. These results suggest that measuring SEPs and SSEPs are meaningful methods for objective assessment in the diagnosis of nerve injury. N1 and N2 of SSEPs can be useful parameters for the evaluation of the nerve function following a needle injury.

• 대한수의학회지
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• 제42권3호
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• pp.397-402
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• 2002

Clinical usefulness of somatosensory evoked potentials (SSEP) as a prognostic tool was evaluated with three dogs showing clinical signs associated with intervertebral disc diseases. Prior to measure SSEP, history taking, physical examination, radiological study and neurological examination were performed. In case 1, poor prognosis was predicted because deep pain was not observed and loss of sensory function was observed in SSEP. And the clinical signs persisted with the conservative treatment. However, in cases 2 and 3, good prognoses were predicted by normal conduction velocity in SSEP that meant the presence of sensory function. The clinical signs of cases 2 and 3 disappeared at days 18 and 13 after treatment, respectively. These results suggest SSEP be used clinically as a prognostic tool in dogs with intervertebral disc diseases.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2004년도 추계학술대회 논문집
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• pp.572-575
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• 2004

Since the 1990s, the advancement of semiconductor technology has resulted in the development of microprocessor technology, auxiliary computer technology, and application technology such as intelligent algorithms (neural network, fuzzy, etc.). These based the development of intelligent machines. An agent is autonomous software that recognizes environment, exchanges knowledge with other agents and makes decisions. We designed agent-based sensor structure. For the purpose, first, it modeled the function of an intelligent machine. Second, it designed sensory function on the agent level.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.359-359
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• 2002

Brain Stimulator processes both visual and audible stimulus and send them human sensory organ. The stimulus was accepted by our sensory organ effect upon human mental function. In this study, we examine the actual effect of commercial brain stimulator using tMRI system.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 하계종합학술대회 논문집(3)
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• pp.139-142
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• 2002

The brain of the human is the best model for the artificial intelligence and is studied by many natural, medical scientists and engineers. In the engineering department, the brain model becomes a main subject in the area of development of a system that can represent and think like human. In this paper, we approach and define the function of the brain biologically and especially, make a model for the function of cerebral cortex, known as a part that performs behavior inference and decision for sensitive information from the thalamus. Therefore, we try to make a model for the transfer process of the brain. The brain takes the sensory information from sensory organ, proceeds behavior inference and decision and finally, commands behavior to the motor nerves. We use the modular neural network in this model. finally, we would like to design the intelligent system that can sense, recognize, think and decide like the brain by learning the information process in the brain with the modular neural network.

• 한국전문물리치료학회지
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• 제5권3호
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• pp.21-33
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• 1998

The purposes of this study were to ascertain differences of the sensory system, central processing system, effector system, and balance ability according to general characteristics (sex, fall experience, and age), and to identify the contributions of the sensory, central processing, and effector system to balance ability in 83 healthy elderly subjects. The subjects were elderly (over 60 years) who live in Wonju City. All subjects participated in six tests (position sense test, visual acuity, vestibular stepping test, Mini-Mental Status Exam-Korea, strength of dorsiflexors, and Berg Balance Test). Collected data were analyzed by the independent t-test, one-way ANOVA, and stepwise multiple regression. The results were as follows: 1. The results of the six tests according to sex showed that vestibular function was significantly better in women than in men. But visual acuity, cognitive function, strength of dorsiflexors, and balance ability were significantly better in men than in women (p<0.05). 2. There were no significant differences in position sense, visual acuity, vestibular function, cognitive function, strength of dorsiflexors, and balance ability between fallers and non-fallers (p>0.05). 3. However, the results of the six tests according to age (group A: 60-69 years, group B: 70-79 years, group C: 80-89 years) showed significant differences in five tests. In the Scheff$\acute{e}$ test, position sense, visual acuity, and cognitive function showed significantly different results between in group A and group C: the strength of the dorsiflexors was significantly different between in group A and group B, and balance ability was significantly different between in group A and group C, and between in group B and group C (p<0.05). 4. Cognitive function and position sense were positively associated with balance ability. Their power of explanation regarding balance ability was 38% (p<0.05). These results suggest that cognitive function and position sense play an important role in balance ability. This would seem to suggest that programs for evaluation or improvement of elderly's balance ability in the elderly should consider cognitive function and position sense.

• 동서간호학연구지
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• 제2권1호
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• pp.22-36
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• 1997

Functional recovery of cerebrovascular accident (CVA) patients were studied by examining functional independence measure (FIM) to evaluate the functional state of the patients at admission to and at discharge from the hospital and its relationship with the family support. Study subjects consisted of 129 CVA patients, who were admitted and received rehabilitation treatment at K Medical Center of Oriental Medicine from August 3 to December 18, 1997. The results were as follows: 1) Total FIM score was $72.37{\pm}25.16$ at admission and $101.67{\pm}22.13$ at discharge. The difference of average score was 29.30, which was statistically significant by paired t-test. 2) The largest difference between FIM scores at admission and at clischarge was observed in items of walking and wheel-chair riding, and the smallest clifference in items of social interaction. 3) The recovery was faster with motor function than with cognitive function, because the difference of FIM scores at admission and at discharge was much larger with motor function. 4) Recovery was better in groups under age 49 than in groups above age 70. Functional recorvery was prominent especially in groups with normal sensory state and speech functions, and groups without urinary incontinence. Recovery was less significantly in patients with paraplegic patients hospitalized longer than 2 months, patients with family all the time, and patients with CVA over 11 days. 5) We could not find any relationship between functional recovery and family support. FIM scores were lower in groups of old age(r=-0.325), long stayed in hospital (r=-0.426), and long period of time after the onset of disease(r= -0.339) with a reciprocal correlation between FIM scores and these parameters. 6) Stepwise multiple regression analysis was done to evaluate factors to affect the recovery from CVA. FIM score at admission could explain 51.2 % of the functional recovery. Important factors were periods of hospitalization, state of sensory function, age, and education (listed in decreasing order of importance). In total, they could explain 64.89% of the functional recovery. These results indicate that functional recovery of CVA patients, who were admitted to oriental medicine hospital for rehabilitation treatment, could be estimated by measuring FIM scores. Recovery was significantly better at discharge from the hospital than at admission and motor function recovery rate was much faster than that of cognitive function. 2. Recommendation Based on these results, we recommend following further studies. 1) Comparative study of recovery of motor function and of sensory function would be necessary by measuring FIM scores once a week to evaluate the recovery of CVA patients. 2) It would be interesting to see whether there is any difference of functional recovery between patients treated with either western medicine or oriental medicine. 3) Psychological factors affecting the recovery of CVA patients need to be studied.

• 대한통합의학회지
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• 제9권2호
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• pp.109-117
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• 2021

Purpose : This study examined the differences in occupational therapists' jobs depending on their past clinical careers using a survey of the importance of occupational therapy tasks in South Korea. This survey sought to provide fundamental data for strengthening occupational therapists' capacities and developing clinical training programs for therapists' future careers. Methods : An online survey was used to collect data from 93 South Korean occupational therapists. The subjects were divided into three groups for the analysis of the importance of occupational therapy tasks, depending on the length of their clinical careers: less than 3 years, from 4 to 6 years, and over 7 years. Results : A within-groups comparison of task importance found that "occupational therapy evaluation" was most important in all three groups. In between-groups comparisons, "patient information check", "assessment planning and establishment", "sensory function assessment", "social skills assessment", "developmental function improvement", "basic daily activities training", "social skills improvement", and "patient education" demonstrated statistically significant differences (p<.05). Each group showed different priorities. In the less-than-3-years group, "understanding of patient's needs" was most important, followed by "arm function improvement", "arm function assessment", "nerve, musculoskeletal, and motor-related functional improvement", and "basic daily activities training". In the 4-to-6-years group, "arm function assessment" was most important, followed by "basic daily activities assessment", "patient's needs", "arm function improvement", and "patient information check". In the over-7-years group, "understanding of patient's needs" was most important, followed by "patient information check", "basic daily activities assessment", "basic daily activities training", and "sensory function assessment". Conclusion : This study found that what occupational therapists consider important in their jobs varies according to their past clinical career and that occupational therapists with more than 7 years' experience are more aware of the importance of diverse fields of occupational therapy. Differentiated education that considers length of career and a range of training programs for more experienced occupational therapists will be needed in the future.

• 생명과학회지
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• 제22권5호
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• pp.613-620
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• 2012

본 연구의 목적은 수면장애가 뇌파(EEG)의 beta파와 감각운동리듬(sensory motor rhythm)에 미치는 영향을 규명하는 것이다. 여자 대학생을 대상으로 하여 수면습관에 따라서 다음과 같이 네 군(n=6)으로 나누었다. 즉, 좋은 수면습관을 가진 GSHG (Good sleep habit group), 일반적으로 대학생들이 늦게 취침하는 수면 습관을 갖고 있기 때문에 오전 0~2시에 취침하는 CSHG (Common sleep habit group), 수면위상지연증후군으로 자신의 수면 장애를 인식하고 있는 CSDG (Cognitive sleep disorder with delayed sleep phase syndrome group), 수면장애를 인식하지 못하는 NSDG (Non-cognitive sleep disorder with delayed sleep phase syndrome group)으로 나누었다. 뇌파는 QEEG 8-System을 사용하여 오전 9~12시 사이에 측정하였다. 책읽기 자극시에 뇌파를 측정하여 안정시 기준치와 비교 분석하였다. 연구 결과, 책읽기 자극시 beta파와 감각운동리듬 상대파워는 GSHG가 다른 세군에 비하여 유의적으로 높았다($p$ <0.05). 책읽기 자극시 수치와 안정시 기준치를 대응 비교하여 볼 때에도, GSHG에서 beta 파워가 대뇌피질의 모든 부위에서 유의적으로 증가하였다($p$ <0.05). 그러나 CSHG에서는 전두부와 측두부에서 beta 파워가 감소하였다($p$ <0.05). 한편 CSDG와 NSDG에서는 책읽기 자극에 의하여 beta 파워의 유의적인 변화가 발생하지 않았다. 감각운동리듬 상대파워는 GSHG에서만 책읽기 자극에 의하여 향상되었다. 결론적으로 여자 대학생에게 있어서 오전 0~2시경에 늦게 취침을 하면 다음날 오전에 집중력 뇌파인 beta파 기능이 현저히 감소하고, 수면습관이 나쁘면 자신의 수면장애에 대한 자가인식 유무와 관련 없이 beta파와 운동감각리듬에 대한 뇌기능이 활성화되지 않아서 집중력에 부정적인 영향을 준다.

• Journal of Microbiology and Biotechnology
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• 제17권1호
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• pp.138-145
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• 2007

Anabaena sensory rhodopsin is a seven transmembrane protein that uses all-trans/13-cis retinal as a chromophore. About 22 residues in the retinal-binding pocket of microbial rhodopsins are conserved and important to control the quality of absorbing light and the function of ion transport or sensory transduction. The absorption maximum is 550 nm in the presence of all-trans retinal at dark. Here, we mutated Pro206 to Glu or Asp, of which the residue is conserved as Asp among all other microbial rhodopsins, and the absorption maximum and pKa of the proton acceptor group were measured by absorption spectroscopy at various pHs. Anabaena rhodopsin was expressed best in Escherichia coli in the absence of extra leader sequence when exogenous all-trans retinal was added. The wild-type Anabaena rhodopsin showed small absorption maximum changes between pH4 and 11. In addition, Pro206Asp showed 46 nm blue-shift at pH7.0. Pro206Glu or Asp may change the contribution to the electron distribution of the retinal that is involved in the major role of color tuning for this pigment. The critical residue Ser86 (Asp 96 position in bacteriorhodopsin: proton donor) for the pumping activity was replaced with Asp, but it did not change the proton pumping activity of Anabaena rhodopsin.