• Title/Summary/Keyword: sensitivity studies

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Performance of pre-treatment 18F-fluorodeoxyglucose positron emission tomography/computed tomography for detecting metastasis in ovarian cancer: a systematic review and meta-analysis

  • Han, Sangwon;Woo, Sungmin;Suh, Chong Hyun;Lee, Jong Jin
    • Journal of Gynecologic Oncology
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    • v.29 no.6
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    • pp.98.1-98.13
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    • 2018
  • Objective: We describe a systematic review and meta-analysis of the performance of ${18}F$-fluorodeoxyglucose ($^{18}F-FDG$) positron emission tomography/computed tomography (PET/CT) for detecting metastasis in ovarian cancer. Methods: MEDLINE and Embase were searched for diagnostic accuracy studies that used $^{18}F-FDG$ PET or PET/CT for pre-treatment staging, using surgical findings as the reference standard. Sensitivities and specificities were pooled and plotted in a hierarchic summary receiver operating characteristic plot. Potential causes of heterogeneity were explored through sensitivity analyses. Results: Eight studies with 594 patients were included. The overall pooled sensitivity and specificity for metastasis were 0.72 (95% confidence interval [CI]=0.61-0.81) and 0.93 (95% CI=0.85-0.97), respectively. There was considerable heterogeneity in sensitivity ($I^2=97.57%$) and specificity ($I^2=96.74%$). In sensitivity analyses, studies that used laparotomy as the reference standard showed significantly higher sensitivity and specificity (0.77; 95% CI=0.67-0.87 and 0.96; 95% CI=0.92-0.99, respectively) than those including diagnostic laparoscopy (0.62; 95% CI=0.46-0.77 and 0.84; 95% CI=0.69-0.99, respectively). Higher specificity was shown in studies that confirmed surgical findings by pathologic evaluation (0.95; 95% CI=0.90-0.99) than in a study without pathologic confirmation (0.69; 95% CI=0.24-1.00). Studies with a lower prevalence of the FDG-avid subtype showed higher specificity (0.97; 95% CI=0.94-1.00) than those with a greater prevalence (0.89; 95% CI=0.80-0.97). Conclusion: Pre-treatment $^{18}F-FDG$ PET/CT shows moderate sensitivity and high specificity for detecting metastasis in ovarian cancer. With its low false-positive rate, it can help select surgical approaches or alternative treatment options.

The Effects of Parental Psychological Control and Boys and Girls' Rejection Sensitivity on Relational Aggression in Elementary School Students (부모의 심리적 통제가 남녀 아동의 관계적 공격성에 미치는 영향과 거부민감성의 매개효과)

  • Lee, Kyung Mi;Park, Ju Hee
    • Korean Journal of Child Studies
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    • v.37 no.4
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    • pp.31-46
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    • 2016
  • Objective: This study examined the influences of maternal and paternal psychological control and children's rejection sensitivity on relational aggression in elementary school students, and investigated whether children's rejection sensitivity mediated the relation of parental psychological control and relational aggression. Methods: The participants of this study were 596 fifth to sixth graders from seven elementary schools located in Seoul, Incheon, and Gyeonggi province. To measure the research variables, the Peer Conflict Scale (Marsee, Kimonis, & Frick, 2004), the Psychological Control Scale (Barber, 1996) and the Children's Rejection Sensitivity Questionnaire (Downey, Lebolt, $Rinc\acute{o}n$, & Freitas, 1998) were used. The data were analyzed by means of descriptive statistics and t -tests. Also, structure equation model (SEM) were used to examine the mediating role of rejection sensitivity. Results: The results of this study were as follows. First, the level of paternal psychological control increased the level of children's relational aggression whereas the level of maternal psychological control had no significant effect on it. In addition, the level of rejection sensitivity had a significant positive influence on the level of relational aggression. These tendencies were observed on both boys and girls. Second, only for boys, rejection sensitivity in upper elementary school students partially mediated the relation between paternal psychological control and relational aggression. Also, for both boys and girls, rejection sensitivity completely mediated the relation between maternal psychological control and relational aggression. Conclusion: In conclusion, the higher the level of paternal psychological control, the higher the level of children's rejection sensitivity, and subsequently the higher the level of their relational aggression.

Gender Sensitivity and Gender Equality Consciousness of Dental Hygiene Students

  • Lim, Hee-Jung;Kim, Ki-Eun;NamKoong, Eun-Jung
    • Journal of dental hygiene science
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    • v.21 no.2
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    • pp.111-118
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    • 2021
  • Background: This study was conducted to identify the level of gender sensitivity and gender equality consciousness among dental hygiene students and to confirm the necessity of gender equality programs in the curriculum. Methods: A self-report questionnaire was conducted with some dental hygiene students using the Gender Sensitivity tool and Korean Gender Egalitarianism Scale for Adolescents (KGES-A). Results: First, the gender equality consciousness of the students who took women's studies was high in the areas of educational life and socio-cultural life, and that of the subjects of grandparent families and Catholic was found to be high in the domestic life area. Second, the gender sensitivity of the subjects who took women's studies was found to be high in all sub-areas. In addition, the gender sensitivity of females was higher in the areas of sexual identity, non-violence, and self-reflection than that of males. That of 4-year college students was higher in the areas of sexual identity, openness to gender roles, and non-violence than that of 3-year college students. In addition, the gender sensitivity of Catholic students was high in the areas of sexual identity and openness to gender roles. Third, gender equality consciousness was found to have an effect depending on whether subjects took women's studies, family type, family type, and religion, and gender sensitivity was found to have an effect depending on whether subjects took women's studies or gender. Conclusion: Since dental hygienist is a profession that targets humans, education that can instill equal awareness and values of humans is important. To inspire gender sensitivity and gender equality consciousness in a prospective professional, it is necessary to conduct programs and education related to gender intelligence within dental hygiene curriculum.

Relations of Maternal Sensitivity and Temperament to linfants Attachment Security (영아의 애착 안정성에 영향을 미치는 변인 : 어머니의 민감성과 영아의 기질)

  • Park, Kyung Ja
    • Korean Journal of Child Studies
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    • v.20 no.3
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    • pp.3-17
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    • 1999
  • Maternal sensitivity and infant temperament were studied in relation to infant attachment security. Subjects were 47 one-year-old infants anti their mothers from intact upper-middle class families. Mothers sorted the Attachment Q-set (Waters, 1987, version 3.0) and filled out the Toddlers Temperament Questionnaire(Chu, 1992). Maternal sensitivity was observed in the home for two 3-hour sessions, and observers completed the Maternal Behavior Q-set(Pederson, Moran et al., 1990). Attachment security scores of the infants, using criterion scores developed with Korean infants, were 42, which is comparable to Previous studies. Infants who were securely attached to mothers showed more secure-based behaviors and compliance, enjoyed physical contacts, and showed less fussy/difficult behaviors with mothers. Mothers of girls were observed to be more sensitive to their infants' signals than mothers of boys. Maternal sensitivity scores were not related to infant security scores. However, maternal sensitivity was related to less compliance to mothers for boys.

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The Effects of University Students' Self-Differentiation and Rejection Sensitivity on Interpersonal Anxiety : Moderated Mediating by Gender (대학생의 자아분화 및 거부민감성이 대인불안에 미치는 영향 : 성별에 따른 조절된 매개효과)

  • Kim, Na Ru Mi;Park, Bu Jin;Kim, Se Young
    • Journal of Families and Better Life
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    • v.34 no.4
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    • pp.111-125
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    • 2016
  • The purpose of this study was to model the relations between male and female university students' self-differentiation, rejection sensitivity, and interpersonal anxiety. Questionnaires from 502 university students in Seoul were analysed. The findings are as follows. Firstly, self-differentiation, rejection sensitivity, and interpersonal anxiety were significantly different according to gender. Secondly, the level of differentiation from family regression was higher for both male and female students. And the lower the rejection sensitivity experiencing in vertical relations became, and the lower the rejection sensitivity on horizontal relations was, the lower the interpersonal anxiety became. Thirdly, it was confirmed that for male students, differentiation from family regression affected rejection sensitivity on horizontal relations, and for females, differentiation from emotional reactivity affected ejection sensitivity on both horizontal and vertical relations. Finally, rejection sensitivity played a full mediation parameter when self-differentiation affected interpersonal anxiety, and it was demonstrated differences by gender. This study was meaningful in that it confirmed the relations between male and female university students' self-differentiation, rejection sensitivity, and interpersonal anxiety.

A GIS-based Environmental Sensitivity Assessment of Geopark - Slope Disaster in Cheongsong UNESCO Global Geopark - (GIS를 활용한 지오파크 환경 민감성 평가 - 청송 세계지질공원의 사면재해 민감성을 중심으로 -)

  • Kim, Hyejin;Sung, Hyo Hyun;Kim, Jisoo;Ahn, Sejin
    • Journal of The Geomorphological Association of Korea
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    • v.27 no.2
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    • pp.81-97
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    • 2020
  • Geopark refers to a single boundary area consisting of a collection of geosites and geotrails, which includes ecological, historical and cultural elements based on geological and geomorphological resources. To ensure the continued development and conservation of existing listed geoparks, it is necessary to carry out an environmental sensitivity analysis of the geopark components by utilizing spatial information from various scales. The objectives of this study are to analyze the environmental sensitivity in Cheongsong UNESCO global geopark in relation with slope disaster using GIS and to understand its spatial distribution in connection with geosites and geotrails. Two types of spatial database were constructed; geosites and geotrails in Cheongsong UNESCO global geopark and spatial data to perform environmental sensitivity. Potential soil loss and slope stability were analyzed to derive environmental sensitivity related to slope hazard. The results showed relatively high environmental sensitivity along the drainage network of Cheongsong UNESCO global geopark. Zonal statistics analysis was conducted for further detailed distribution of environmental sensitivity based on buffer zones of geosites and geotrails. Majority of geological sites, geological trails, Jeolgol gorge~Jusan Pond section in hiking trails, and Dalgi Mineral Spring Site~Artistic Genius Republic of Korea(Jangnankki gonghwaguk) section in road areas show relatively high slope hazard sensitivity within buffer zones.

The Effects of Parentification of Early Adult Non-disabled Siblings on Ambivalence over Emotional Expression and Moderating Effects of Rejection Sensitivity (성인초기 비장애형제자매의 부모화 경험이 정서표현양가성에 미치는 영향과 거부민감성의 조절효과)

  • Son, Juhee;Park, Juhee
    • Human Ecology Research
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    • v.57 no.3
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    • pp.445-457
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    • 2019
  • This study investigated the impact of parentification on ambivalence over the emotional expression of early adults who had a sibling with disabilities and examined if rejection sensitivity moderated the relationship of parentification and ambivalence over emotional expression. Participants consisted of 116 siblings in early adulthood who had a sibling with disabilities (45 male; 71 female). The data were collected from 13 centers for family disability, four community rehabilitation centers, three parent societies for people with disabilities, and three self-help groups in Seoul, Busan, and Gyeonggi province. The levels of ambivalence over emotional expression, parentification, and rejecton sensitivity were measured by the Ambivalence over Emotional Expression Questionnaire (King & Emmons, 1990), the Filial Responsibility Scale-Adult (Jurkovic, Thirkield, & Morrell, 2001), and the Rejection Sensitivity Questionnaire (Downey & Feldman, 1996), respectively. The PROCESS Macro program examined the moderating model. The Results indicated that both levels of parentification and rejection sensitivity increased the level of ambivalence over emotional expression of non-disabled siblings. In addition, rejection sensitivity moderated the effect of parentification on ambivalence over emotional expression. The influence of parentification on ambivalence over emotional expression was greater when the level of rejection sensitivity was high, compared to when it was low.

Infant-Child Care Teacher Interaction : Infant Development, Teachers' Sensitivity and Early Home Environment (보육시설에서의 영아-교사 상호작용과 영아의 발달수준, 교사의 민감성 및 초기 가정환경 간의 관련성에 관한 연구)

  • Choi, Eun-Jung;Ha, Ji-Young;Seo, So-Jung
    • Korean Journal of Child Studies
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    • v.30 no.2
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    • pp.71-95
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    • 2009
  • This study investigated relationships among infant development, teacher's sensitivity, home literacy environment, and infant-teacher interaction in the child care setting. Verbal and behavioral interactions between 30 2-year-old infant-teacher pairs were video-recorded during free play activities; teachers' sensitivity was observed by trained observers; infant development was assessed by teachers; data on the early home literacy environment were gathered through maternal self-reported questionnaires. Data were analyzed by descriptive statistics, t-tests, and correlation analyses. Results indicated that boys showed more naming; girls showed more physical contact with teachers. Infants high in overall developmental level showed more behavioral interaction with teachers. Teacher's sensitivity correlated positively with behavioral imitating and negatively with questioning and nodding. Verbal interaction in the home correlated positively with nodding.

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An Analysis of Variables Affecting Teacher Sensitivity of Infant Classes in Childcare Centers: Focus on Emotional Stability, Interpersonal Relationship Stress and Work Environment Variables (영아반 보육교사의 교사민감성에 영향을 미치는 변인 분석: 정서안정성, 대인관계 스트레스, 근무환경을 중심으로)

  • Jeong, Yujeong;Kim, Jinwook
    • Korean Journal of Child Studies
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    • v.38 no.2
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    • pp.205-218
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    • 2017
  • Objective: This study examined the correlation between variables influencing teacher sensitivity to infant classes in Educare Center teachers and teacher sensitivity, by classifying their personal psychological, socio-psychological, and work environment variables. Furthermore, it aimed to inquire the extent to which these variables influence teacher sensitivity. Methods: The study included 236 Educare Center teachers in charge of infant classes working in infant-caring facilities. Based on stepwise multiple regression analysis, a significance test was conducted for each variable. Results: Firstly, according to the correlations regarding teacher sensitivity to infant classes, for sensitive interaction, emotional stability showed significant positive correlation, while there were significant negative correlations with relationships with the director, colleagues,and parents; mean working hours in other places; and mean daily personal time. For insensitive interaction, there were significant negative correlations with emotional stability and mean daily break time, while there were significant positive correlations with relationships with the director, colleagues, and parents. Secondly, regarding the influences on teacher sensitivity to infant classes, for sensitive interaction, the most significant influences consisted in the relationships with colleagues and parents. On the other hand, for insensitive interaction, the most significant influences were the relationship with colleagues and emotional stability. Conclusion: Reducing interpersonal relationship stress and increasing the emotional stability of Educare Center teachers will increase their sensitivity level. Furthermore, the quality of care will be improved.

An Efficient Algorithm for Design Sensitivity Analysis of railway Vehicle Systems (철도차량의 설계 민감도 해석을 위한 효율적인 알고리즘 개발)

  • 배대성;조희제;백성호;이관섭;조연옥
    • Proceedings of the KSR Conference
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    • 1998.05a
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    • pp.299-306
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    • 1998
  • Design sensitivity analysis of a mechanical system is an essential tool for design optimization and trade-off studies. This paper presents an efficient algorithm for the design sensitivity analysis of railway vehicle systems, using the direct differentiation method. The cartesian coordinate is employed as the generalized coordinate. The governing equations of the design sensitivity analysis are formulated as the differential equations. Design sensitivity analysis of railway vehicle systems is performed to show the validity and efficiency of the proposed method.

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