• Smart Structures and Systems
• /
• 제8권1호
• /
• pp.17-37
• /
• 2011

The microcantilever (MCL) sensor is one of the most promising platforms for next-generation label-free biosensing applications. It outperforms conventional label-free detection methods in terms of portability and parallelization. In this paper, an overview of recent advances in our understanding of the coupling between biomolecular interactions and MCL responses is given. A dual compact optical MCL sensing platform was built to enable biosensing experiments both in gas-phase environments and in solutions. The thermal bimorph effect was found to be an effective nanomanipulator for the MCL platform calibration. The study of the alkanethiol self-assembly monolayer (SAM) chain length effect revealed that 1-octanethiol ($C_8H_{17}SH$) induced a larger deflection than that from 1-dodecanethiol ($C_{12}H_{25}SH$) in solutions. Using the clinically relevant biomarker C-reactive protein (CRP), we revealed that the analytical sensitivity of the MCL reached a diagnostic level of $1{\sim}500{\mu}g/ml$ within a 7% coefficient of variation. Using grazing incident x-ray diffractometer (GIXRD) analysis, we found that the gold surface was dominated by the (111) crystalline plane. Moreover, using X-ray photoelectron spectroscopy (XPS) analysis, we confirmed that the Au-S covalent bonds occurred in SAM adsorption whereas CRP molecular bindings occurred in protein analysis. First principles density functional theory (DFT) simulations were also used to examine biomolecular adsorption mechanisms. Multiscale modeling was then developed to connect the interactions at the molecular level with the MCL mechanical response. The alkanethiol SAM chain length effect in air was successfully predicted using the multiscale scheme.

• 대한기계학회논문집
• /
• 제14권6호
• /
• pp.1613-1620
• /
• 1990

본 연구에서는 일반적인 레이저 유속계를 사용하여 광전 증폭관내에 핀흘 대 신에 슬릿(slit)을 장치하고 광전증폭관을 측정영역에 90˚가 되도록 설치하여 in-situ calibration을 수행함으로써 분무의 입경과 속도를 동시에 계측할수 있다는 Yoon의 결과를 이용하고 모든 입자들의 궤적은 동일한 확률을 갖는다는 Yule와 Holve, Self의 가정을 기초로한 수학적인 Deconvolution에 의하여 계측방법에 발생되는 모순 점을 해결하였다. 일반적으로 분무특성해석을 위해서는 분무를 지배하는 기하학적인 변수, 입경분포, 액적의 속도분포, 밀도분포, 입경과 속도의 상관계수, 입자의 증발율 등이 규명 되어야하는데 본 연구에서는 이상류 동축노즐을 제작하고 이의 분무특성을 해석하기위하여 액적의 속도분포, 입경분포, 입경과 속도의 상관계수, 수밀도분포 등 을 계측하였다.

• Ocean and Polar Research
• /
• 제39권2호
• /
• pp.159-168
• /
• 2017

To evaluate the accuracy of UAV photogrammetry for Hyangho coast, eastern coast of Korea, we conducted a field experiment wherein UAV photogrammetry test was repeated three times. Since the Haygho coast is located within a military reservation zone, it was necessary to obtain permission to gain access to the beach and to have sensitive aerial photographs showing military facilities inspected and cropped. The standard deviation of the UAV shooting position between the three tests was less than 1 m, but repeatability of footprint on the ground was low due to wind-driven variability of the UAV pose. Self-calibrating bundle adjustment(SCBA) of implementing non-metric camera calibration was failed in one test. In two tests, the vertical error was twice as large as the pixel size except for those areas that were subject to security inspection and cropping. Given the problems that can arise with regard to the repeatability of the shooting area as well as the possibility of failure with regard to SCBA, we strongly recommend that UAV photogrammetry in coastal areas needs to be repeated at least twice.

• 대한치과기공학회지
• /
• 제39권3호
• /
• pp.161-167
• /
• 2017

Purpose: We compare the bond strength of heat-cured PMMA of Lucitone 199 and QC-20 and Tokuyama Rebase Resin of self-cured resin, which are widely used and well accepted in clinical practice. In order to test the mechanical bonding and chemical bonding, we will compare the bond strength between EstheShot Bright, Smiletone, Repair and Rebase resins. Methods: The denture base resin used in this study was PMMA heat-cured QC-20 and Lucitone 199, polyamide resin EstheShot Bright, Smiletone. And Two types of self-curing Rapid Repair and Tokuyama Rebase were used as resection resins. To measure the bond strength, the denture specimens were fabricated in the size of $10{\times}64{\times}3.5mm$ as instructed by the manufacturer. A surface treatment agent was applied to the cut surfaces of each denture specimen, and the specimens were placed in a preformed silicone mold, and autoclaved excimer resins were prepared. The bending strength of the fabricated specimens was measured using a universal testing machine (STM-5, United Calibration Co., U.S.A.) to measure the three-point bending strength. Results: In both polycarbonate and polyacetal resin, a special resin surface treatment agent showed higher bonding strength than the resin surface treatment agent(p<0.05). Regardless of the type of surface treatment, polycarbonate showed higher bond strength than polyacetal resin(p<0.05). Conclusion: It is considered desirable to use a special surface treating agent for the thermoplastic denture base resin such as polycarbonate and polyacetal resin.

• 한국정밀공학회지
• /
• 제31권7호
• /
• pp.605-613
• /
• 2014

Scanning white-light interferometry is an important measurement option for many surfaces. However, serious profile measurement errors can be present when measuring free-form surfaces being highly curved or tilted. When the object surface slope is not zero, the object and reference rays are no longer common path and optical aberrations impact the measurement. Aberrations mainly occur at the beam splitter in the interference objective and from misalignment in the optical system. Both effects distort the white-light interference signal when the surface slope is not zero. In this paper, we describe a modified version of white-light interferometry for eliminating these measurement errors and improving the accuracy of white-light interferometry. Moreover, we report systematic errors that are caused by optical aberrations when the object is not flat, and compare our proposed method with the conventional processing algorithm using the random ball test.

• Steel and Composite Structures
• /
• 제18권4호
• /
• pp.833-852
• /
• 2015

Self-compacting Concrete Filled steel Tubes (SCFT), which combines the advantages of steel and concrete materials, can be applied to strengthen the RC columns. In order to investigate the eccentric loading behavior of the strengthened columns, this paper presents an experimental and numerical investigation on them. The experimental results showed that the use of SCFT is interesting since the ductility and the bearing capacity of the RC columns are greatly improved. And the performance of strengthened columns is significantly affected by four parameters: column section type (circular and square), wall thickness of the steel tube, designed strength grade of strengthening concrete and initial eccentricity. In the numerical program, a generic fiber element model which takes in account the effect of confinement is developed to predict the behavior of the strengthened columns subjected to eccentric loading. After the fiber element analysis was verified against experimental results, a simple design formula based on the model is proposed to calculate the ultimate eccentric strength. Calibration of the calculated results against the test results shows that the design formula closely estimates the ultimate capacities of the eccentrically compressed strengthened columns by 5%.

• Journal of Astronomy and Space Sciences
• /
• 제12권1호
• /
• pp.66-77
• /
• 1995

비례계수관에서 생성되는 신호의 상승시간을 비교하여 X-선과 비 X-선 신호를 구분하는것이 가능하다. 과학로케트 탑재형 비례계수관에 응용하여 백그라운드를 제거하기 위한 간단한 상승시간 선별회로를 개발하였다. 제작된 전체 회로는 상승시간 측정회로, 측정된 시간을 진폭으로 변환시켜주는 시간-진폭 변환회로로 구성되며, 시산 대 진폭을 검교정할 수 있는 회로를 부가하였다. 제작된 회로를 X-선 검출 시스템에 적용한 결과 2~12 keV에너지 범위에서 전반적인 백그라운드 제거율을 80% 이상 얻을 수 있었으며, 약 12 keV 이상의 높은 에너지내에서는 상승시간 선별법을 사용하기 어려운 제한성을 확인하였다.

• 대한전자공학회논문지SP
• /
• 제38권6호
• /
• pp.657-664
• /
• 2001

최근에 물체영상들로부터 3차원 물체 모델을 복원할 수 있는 셀프캘리브레이션 기술에 대한 연구가 활발히 진행되고 있다. 이 셀프캘리브레이션 기술의 핵심은 F행렬이며, 복원되는 3차원 물체 모델의 정확도는 물체영상들 사이에서 유도해내는 F행렬의 추정의 정확도에 좌우된다. F행렬을 추정하기 위해 일반적으로 선형최소화방법이 적용되고있다. 그러나 본 논문에서는 보다더 정확한 F행렬의 추정을 위해 비선형 최소화방법인 Levenberg-Marquardt 기법을 적용하였다. 또한 F행렬의 정확도를 감소시키는 부정확한 대응점들 (corresponding points)과 오차를 많이 포함하고 있는 대응점들, 즉 outliers를 Monte Carlo 기술을 적용하여 제거하였다. 본 논문에서 적용한 방법들로 추정한 F행렬의 정확도를 분석한 결과, outliers를 제거하기 전보다 제거한 후의 정확도가 31% 향상되었고, 선형적 추정 F행렬보다 비선형적 추정 F행렬이 22% 향상되었음을 알 수 있었다.

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 1992년도 추계학술대회 논문집
• /
• pp.114-117
• /
• 1992

본 논문에서는 자기적분형 자계센서의 설계방법과 교정방법을 제안하고, 파도대전류에 의하여 형성되는 자계에 대한 거리-응답 특성시험과 주파수 변화에 대한 응답도의 측정을 수행하였다. 자기적분형 센서는 적분저항의 증가와 더불어 감지전압은 상승하였으나 감쇠시간은 줄어드는 특성을 나타내었다. 또한 전기적 등가회로를 구성하여 이론적으로 해석 한 바 실험결과와 잘 일치하였다.

• Journal of Preventive Medicine and Public Health
• /
• 제6권1호
• /
• pp.65-70
• /
• 1973

The study in the fild of medical instrument has been out of the interest by any of the life scientist in Korea. Especially, the recent developments in the medical electromics are remarkable one. Authors planned this study to ascertain the possibility of setting up the thermister thermometer with available accessories of demestic prouducts including some specific foreign assembly parts. By proper use of the thermister as one of the wheatstone bridge, we could detect tile resistance variations due to the environmental temperature variace. The intensive care for the bridge circuit and compensation scheme was required. The calibration procedure adopted here makes it possible to read the current as the temperature. The temperature range was determined by the examination and construction of the graph of the resistance-temperature variation. The determination of electric current, available ambient-temperature, the reduction of excessive current and self-heating of the thermister were made. Renovation in response-velocity was under taken too. This electronic thermometer was designed and assembled by the circuitry developed in accordance with the maximum availability of domestic products with some foreign-made parts. The result of our experiment showed very stable function and proved to be the most promissing item in the actual application as long as the thermistor thermister is concerned.