• Title/Summary/Keyword: screening strategy

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DISCRIMINATION BETWEEN VIRGIN OLIVE OILS FROM CRETE AND THE PELOPONESE USING NEAR INFRARED TRANSFLECTANCE SPECTROSCOPY

  • Flynn, Stephen J.;Downey, Gerard
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1520-1520
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    • 2001
  • Food adulteration is a serious consumer fraud and a potentially dangerous practice. Regulatory authorities and food processors require a rapid, non-destructive test to accurately confirm authenticity in a range of food products and raw materials. Olive oil is prime target for adulteration either on the basis of the processing treatments used for its extraction (extra virgin vs virgin vs ordinary oil) or its geographical origin (e.g. Greek vs Italian vs Spanish). As part of an investigation into this problem, some preliminary work focused on the ability of near infrared spectroscopy to discriminate between virgin olive oils from separate regions of the Mediterranean i. e. Crete and the Peloponese. A total of 46 oils were collected: 18 originated in Crete and 28 in the Peloponese. Oils were stored in a temperature-controlled room at 2$0^{\circ}C$ prior to spectral collection at room temperature (15-18$^{\circ}C$). Samples (approximately 0.5$m\ell$) were placed in the centre of the quartz window in a camlock reflectance cell; the gold-plated baking plate was then gently placed into the cell against the glass so as to minimize the formation of air bubbles. The rear of the camlock cell was then screwed into place producing a sample thickness of 0.5mm. Spectra were recorded between 400 and 2498nm at 2nm intervals on a NIR Systems 6500 scanning monochromator. Spectral collection took place over 2-3 days. Data were analysed using both WINISI and The Unscrambler software to investigate the possibility of discriminating between the oils from Crete and the Peloponese. A number of data pre-treatments were used and discriminant models were developed using discriminant PLS (WINISI & Unscrambler) and SIMCA (Unscrambler). Despite the small number of samples involved, a satisfactory discrimination between these two oil types was achieved. Graphical examination of principal component scores for each oil type also holds out the possibility of separating oils from either Crete and the Peloponese on the basis of districts within each region. These preliminary data suggest the potential of near infrared spectroscopy to act as a screening technique for the confirmation of geographic origin of extra virgin olive oils. The sample presentation strategy adopted uses only small volumes of material and produces high quality spectra.

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Development of CRS-Korea II and its Application to Setting the Priority of Toxic Chemicals for Local Provinces (개선된 화학물질 우선순위 선정 기법(CRS-Korea II)과 그 활용을 통한 지역별 유독물 우선순위의 도출)

  • Choi Seung Pil;Park Hoa Sung;Lee Dong Soo;Shin Yong Seung;Kim Ye Shin;Shin Dong Chun
    • Environmental Analysis Health and Toxicology
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    • v.20 no.4 s.51
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    • pp.311-325
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    • 2005
  • A chemical ranking and scoring system, CRS - Korea, has recently been developed and proposed to use to prioritize on a screening level the toxic chemicals for monitoring and risk assessment. As CRS-Korea requires rigorous assessments prior to its wide application, an assessment was conducted in this study by examining the contribution of individual parameter score to the final chemical score or ranking. The sensitivity of the system to the default values for various parameters of missing data was also tested. The chemical ranking/score was round to depend primarily on the score of a single parameter, i. e., the chemical release, while toxicity scores show little correlation with the priority Further analysis indicated that the dominating effect of the chemical release results from i) its multiplicative relationship with the other two exposure parameters (biodegradation and persistent) and ii) the fact that a maximum score of 10 was assigned to the chemical release parameter while 5 was assigned for all others. AE the fraction of the data that are missing exceeded $70\%$ for various toxicity parameters at compared to less than $10\%$ for exposure parameters, the sensitivity of the ranking to the default value was not significant (rank correlation coefficient = 0.98) for toxicity parameters. Bated on this assessment, an improved CRS system (CRS - Korea II) was proposed in which the impact of the chemical release was properly adjusted by changing the multiplicative relationship to additive one and the maximum score to 5. Chemical priority was derived for each of 16 provinces by using CRS-Korea II. The chemical priority was found to significantly vary among the provinces. It was concluded that not only the national chemical priority but the local chemical priority should be taken into account in setting the nationwide chemical monitoring and risk assessment strategy.

Influence of Fear of Evaluation, Test Anxiety, and Social Anxiety among Nursing Students (간호대학생의 평가두려움과 시험불안이 사회불안에 미치는 영향)

  • Cho, Ok-Hee;Hwang, Kyung-Hye;Lim, Jong-mi
    • The Journal of the Korea Contents Association
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    • v.17 no.7
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    • pp.56-66
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    • 2017
  • This study is a descriptive research study conducted to investigate the influence of fear of evaluation and test anxiety on social anxiety among nursing students. The subjects were 383 nursing students in a university and surveyed the structured questionnaires for evaluation fear, test anxiety and social anxiety from June to July 2015. As a result, it was found that fear of positive evaluation, fear of negative evaluation and test anxiety were found to affect social anxiety, and these variables predicted social anxiety of nursing students by 30%. The social anxiety of nursing students verified differences according to the economic condition, satisfaction of major in nursing, and academic stress, and that there was a positive correlation between fear of positive evaluation (r=.45, p<.001), fear of negative evaluation (r=.29, p<.001) and test anxiety (r=.29, p<.001). This study is significant in that fear of evaluation and test anxiety of nursing students are verified to be factors affecting social anxiety. We suggest that a social anxiety intervention program be developed and applied for nursing students. Also, it is necessary secure a strategy to apply the intervention program by screening social anxiety of nursing students in advance.

Factors Influencing Limerence in Dating Relationships among Female College Students (여대생을 대상으로 한 이성 교제의 집착 행동에 영향을 주는 요인)

  • Kim, Oksoo;Jeon, Hae Ok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.2
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    • pp.304-314
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    • 2020
  • This cross-sectional descriptive study investigated the influence of romantic relationships' characteristics, self-esteem and sexual autonomy on limerence in dating relationships among female college students who had or were currently engaged in a dating relationship. The data was collected through self-reported structured questionnaires from 167 female Korean college students using convenient sampling methods from November 25, 2012 to December 20, 2012. The data was analyzed using t-tests, one-way analyses of variance, Scheffe's test, Pearson's correlation coefficients, and multiple linear regression analysis with the IBM SPSS 23.0 program. The results showed that a significant difference was found in limerence according to the frequency of experiencing romantic breakup (F=4.16, p=.003), and limerence in dating relationships was negatively correlated with self-esteem (r=-.31, p<.001) and sexual autonomy (r=-.21, p=.006). Self-esteem and the frequency of romantic breakups explained 20% of limerence in dating relationships among the participants (F=8.03, p<.001). Therefore, as a strategy to solve the problems related to limerence during the period of dating, cognitive and educational interventions are needed to strengthen the self-esteem and sexual autonomy of college students who have had a high number of separations. In addition, early screening of college students with risk factors for limerence and providing problem-solving based counseling will help improve their psychological health.

Analysis on Deciles Distribution Behaviors of Four Major Korean Movie Distribution Companies and the Rest (한국 영화 4대 배급사의 흥행 10분위 기반 배급 행태 분석)

  • Kim, Jung-Ho;Kim, Jae Sung
    • The Journal of the Korea Contents Association
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    • v.16 no.6
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    • pp.305-322
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    • 2016
  • With the multiplex and wide release strategy, the monopolies of four major distribution companies and three multiplex chain, the polarization of Korean movie's Box Office performance is deepening. The four major distributor of NEW, CJ CGV, Lotte Cinema distributed 290 movies of 538 movies produced from 2009 to 2014 in Korea. The audience market share of these four distributors is 85.74%, while other 248 movies covers only 14.26%, which are distributed by outsides of the four major distribution system. The concentration of film admission has been deepened in Gini Index from 0.53 in 2004 to 0.85 in 2014. The movies distributed by others rather than four major companies suffers inequality in numbers of secured screens, screening times, and secured seats of movie theaters. In the highest 10% of box-office ranking, there is only one movie distributed by others. The lowest 50% of box-office ranking, there are 186 movies by others, while four companies have 81 movies. However, Occupancy rate of seat of major companies is lower than 16.83% of that of the others in the lowest 50% section. Workers of Korean movie industry are suffered from this polarization and they seek their breakthrough by producing erotic movies for VOD in recent years.

Comparison of Factors Affecting According to the Quality of Life Level in Korean Adults with Diabetes Mellitus (한국 당뇨병 성인의 삶의 질 수준에 따른 영향요인 비교)

  • Bang, So-Youn
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.5
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    • pp.607-614
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    • 2020
  • This secondary analysis study used the 2015 Korea Health Panel data to identify the difference of factors affecting the quality of life (QoL) of Korean adults with diabetes mellitus (DM). The data from 1,343 subjects who met the criteria for screening was analyzed by multiple linear regression and quantile regression analyses. As a result, the average QoL of the subjects was .86 (±.14). The factors affecting the QoL of the subjects were age, gender, education level, spouse, economic activity, type of health insurance, and regular physical activity (all p<.05). However, there were differences of the results when dividing the subjects into three groups according to their QoL level. The factors for the lower 25% group were age, gender, education level, spouse, economic activity, type of health insurance, and regular physical activity, and those factors for the middle 50% group were age, gender, education level, spouse, type of health insurance, and regular physical activity, and those factors for the top 75% group were spouse, economic activity, household income, type of health insurance, and duration of DM. Based on these results, it is important to develop and provide a differentiated intervention strategy that considers the influential factors in order to improve the QoL of Korean adults with DM.

The Effect of Equatorial Spread F on Relative Orbit Determination of GRACE Using Differenced GPS Observations (DGPS기반 GRACE의 상대궤도결정과 Equatorial Spread F의 영향)

  • Roh, Kyoung-Min;Luehr, Hermann;Park, Sang-Young;Cho, Jung-Ho
    • Journal of Astronomy and Space Sciences
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    • v.26 no.4
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    • pp.499-510
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    • 2009
  • In this paper, relative orbit of Low Earth Orbit satellites is determined using only GPS measurements and the effects of Equatorial Spread-F (ESF), that is one of biggest ionospheric irregularities, are investigated. First, relative orbit determiation process is constructed based on doubly differenced GPS observations. In order to see orbit determination performance, relative orbit of two GRACE satellites is estimated for one month in 2004 when no ESF is observed. The root mean square of the achieved baselines compared with that from K-Band Ranger sensor is about 2~3 mm and average of 95% of ambiguities are resolved. Based on this performance, the relative orbit is estimated for two weeks of two difference years, 2003 when there are lots of ESF occurred, and 2004 when only few ESF occurred. For 2003, the averaged baseline error over two weeks is about 15 mm. That is about 4 times larger than the case of 2004 (3.6 mm). Ionospheric status achieved from K-Band Ranging sensor also shows that more Equatorial Spread-F occurred at 2003 than 2004. Investigation on raw observations and screening process revealed that the ionospheric irregualarities caused by Equatorial Spread-F gave significant effects on GPS signal like signal loss or enhancement ionospheric error, From this study, relative orbit determination using GPS observations should consider the effect of Equatorial Spread-F and adjust orbit determination strategy, especially at the time of solar maximum.

A Systematic Review and Meta-analysis of Sensory Integration Intervention Studies in Children with Cerebral Palsy (뇌성마비 아동의 감각통합 중재 연구에 대한 체계적 고찰과 메타분석)

  • Kim, Eun-Joo;Choi, Yoo-Im
    • Journal of Digital Convergence
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    • v.11 no.4
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    • pp.383-389
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    • 2013
  • The purpose of this study was to investigate evidence-based practice (EBP) for sensory integration (SI) intervention in children with cerebral palsy (CP) through a systematic review and meta analysis. The screening strategy was performed to select studies for analysis after that, a meta-analysis was implemented for calculating the effect size (ES) in group studies. Twenty-four studies were included for a systematic review and included seven case reports, three single-subject designs, and fourteen group experimental design studies(three randomized controlled trials, three two groups nonrandomized studies, and six one group nonrandomized studies). The ES of the experimental group studies was moderate size of 0.272. The results of the ES according to the dependent variables, the ES was the largest in the fine motor development. The effect size of the published papers was greater than the unpublished paper's and two groups nonrandomized studies' size effect was the largest in the design. The ES of the infants was larger than the children. The ES for a period of 8 weeks, the number of five times a week, and time in 90 minutes showed the biggest in SI program. Although the ES of SI intervention in children with CP showed moderate effect, accumulation of research well be needed.

In Vitro Screening for Anti-Dementia Activities of Seaweed Extracts (해조류 추출물의 In Vitro 항치매 활성)

  • Son, Hyun Jung;Um, Min Young;Kim, Inho;Cho, Suengmok;Han, Daeseok;Lee, Changho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.7
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    • pp.966-972
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    • 2016
  • We investigated that methanolic extracts of 20 kinds of seaweeds from Jeju Island for their antioxidant activities, acetylcholinesterase and ${\beta}$-secretase inhibitory activities, and neuronal survival in order to evaluate their potentials as anti-dementia agents. Ecklonia cava extracts had the highest total polyphenol content among the 20 seaweed extracts. The antioxidant activity of seaweed extracts was measured by using 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay. It was found that Ecklonia kurome extracts had the highest ABTS scavenging activity ($IC_{50}=0.07{\pm}0.01mg/mL$). As a result, Ecklonia cava, Ecklonia kurome, and Myelophycus simplex extracts were found to be the most effective in terms of acetylcholinesterase inhibitory activity. In the ${\beta}$-secretase activity assay, Ecklonia cava and Ecklonia kurome extracts were effectively inhibited ($84.41{\pm}1.70%$ and $81.17{\pm}2.43%$, respectively). As expected, neuronal cell death induced by $H_2O_2$ in SH-SY5Y cells was diminished by Ecklonia cava, Ecklonia kurome, and Sargassum yezoense extracts. Taken together, these results showed that Ecklonia cava extract has potential anti-dementia activity, which suggests that it might provide an effective strategy for improving dementia.

The Effects of Cesium, Strontium and Cobalt on Cell Toxicity in the 2D and 3D Cell Culture Platforms (단층 및 입체 세포배양환경에서 세슘, 스트론튬 및 코발트가 세포 독성에 미치는 영향 분석)

  • Kim, Gi Yong;Kang, Sung-Min;Jang, Sung-Chan;Huh, Yun Suk;Roh, Changhyun
    • Korean Journal of Environmental Biology
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    • v.34 no.2
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    • pp.107-115
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    • 2016
  • Currently, there are 442 operating nuclear power plants in the world, and 62 more are under construction. According to this reasoning, the treatment of radioactive waste is important to prevent the environmental ecosystem including humans, animals, and plants. Especially, a leakage of radioactive waste causes not only regional problem but also serious global one. In this study, we demonstrate the effect of radioisotopes (e.g., cesium, strontium, and cobalt) on a 3D culture cell. To develop the 3D cell culture system, we used a 96-well-culture plate with biocompatible agarose hydrogel. Using this method, we can perform the 3D cell culture system with three different cell lines such as HeLa, HepG2, and COS-7. In addition, we conducted a cell viability test in the presence of radioisotopes. Interestingly, the 3D morphological cells showed 42% higher cell viability than those on the 2D against cesium. This result indicates that the 3D platform provides cells morphological and physiological characteristic similar to in vivo grown tissues. Moreover, it overcomes the limitation of conventional cell culture system that can't reflect in vivo systems. Finally, we believe that the proposed approach can be applied a new strategy for simple high-throughput screening and accurate evaluation of metal toxicity assay.