• 제목/요약/키워드: screening assessment

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The Ecological Health Screening Assessment of Agricultural area using Biomarkers and Bioindicators in Misgurnus Anguillicaudatus (case study) (미꾸리의 생물지표를 이용한 농업지역의 수생태계 건강성 스크리닝 평가(사례연구))

  • Kim, Ja-Hyun;Han, Sun-Young;Yeom, Dong-Hyuk
    • The Korean Journal of Pesticide Science
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    • v.16 no.1
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    • pp.62-68
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    • 2012
  • This study evaluated the screening level assessment of ecological health using four biomarkers and four bioindicators of Misgurnus anguillicaudatus as a indicator species in agricultural area of South Korea during May-June 2011. The endocrine disrupting chemical (EDC) indicators, such as vitellogenin (VTG) and gonado-somatic index (GSI), were not significantly changed in the agricultural site (p>0.05), indicating no effects. The biomarkers and bioindicators were compared between two sites of reference site (RS) and the agricultural site (AS) for screening assessment of ecological health. The ethoxyresorufin-O-deethylase (EROD) activity, acetylcholinesterase (AChE) activity, and DNA damage were significantly changed in the AS compared with the RS (p<0.05). But the individual level bioindicators such as condition factor (CF), hepato-somatic index (HSI), and gonado-somatic index (GSI) were not significantly different from reference site (RS). These results may indicate impairments of ecological health by toxic chemicals and environmental conditions. Current this study is based on screening assessment of biochemical and individual level biomarkers and bioindicators, so further study is required additional biomarkers and population or community level bioindicators for more specific health assessments in agricultural areas.

Screening Method for Flow-induced Vibration of Piping Systems for APR1400 Comprehensive Vibration Assessment Program (APR1400 종합진동평가를 위한 배관시스템의 유동유발진동 간이평가)

  • Ko, Do-Young;Kim, Dong-Hak
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.25 no.9
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    • pp.599-605
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    • 2015
  • The revised U.S. Nuclear Regulatory Commission(NRC), Regulatory Guide(RG) 1.20, rev.3 requires the evaluation of the potential adverse effects from pressure fluctuations and vibrations on piping and components for the reactor coolant, steam, feedwater, and condensate systems. Detailed vibration analyses for the systems attached to the steam generator are very difficult, because these piping systems are very complicated. This paper suggests a screening method for the flow-induced vibration of acoustic resonances and pump-induced vibration of the piping systems attached to the steam generator in order to conduct the APR1400 comprehensive vibration assessment program. This paper seeks to address the areas such as potential vibration sources, and methods to prevent the occurrence of acoustic resonances and pump-induced vibration of piping systems attached to the steam generator, for conducting the APR1400 comprehensive vibration assessment program. The screening method in this paper will be used to estimate the flow-induced vibration of the piping systems attached to the steam generator for the APR1400.

Development of a Fire Human Reliability Analysis Procedure for Full Power Operation of the Korean Nuclear Power Plants (국내 전출력 원전 적용 화재 인간신뢰도분석 절차 개발)

  • Choi, Sun Yeong;Kang, Dae Il
    • Journal of the Korean Society of Safety
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    • v.35 no.1
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    • pp.87-96
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    • 2020
  • The purpose of this paper is to develop a fire HRA (Human Reliability Analysis) procedure for full power operation of domestic NPPs (Nuclear Power Plants). For the development of fire HRA procedure, the recent research results of NUREG-1921 in an effort to meet the requirements of the ASME/ANS PRA Standard were reviewed. The K-HRA method, a standard method for HRA of a domestic level 1 PSA (Probabilistic Safety Assessment) and fire related procedures in domestic NPPs were reviewed. Based on the review, a procedure for the fire HRA required for a domestic fire PSA based on the K-HRA method was developed. To this end, HRA issues such as new operator actions required in the event of a fire and complexity of fire situations were considered. Based on the four kinds of HFE (Human Failure Event) developed for a fire HRA in this research, a qualitative analysis such as feasibility evaluation was suggested. And also a quantitative analysis process which consists of screening analysis and detailed analysis was proposed. For the qualitative analysis, a screening analysis by NUREG-1921 was used. In this research, the screening criteria for the screening analysis was modified to reduce vague description and to reflect recent experimental results. For a detailed analysis, the K-HRA method and scoping analysis by NUREG-1921 were adopted. To apply K-HRA to fire HRA for quantification, efforts to modify PSFs (Performance Shaping Factors) of K-HRA to reflect fire situation and effects were made. For example, an absence of STA (Shift Technical Advisor) to command a fire brigade at a fire area is considered and the absence time should be reflected for a HEP (Human Error Probability) quantification. Based on the fire HRA procedure developed in this paper, a case study for HEP quantification such as a screening analysis and detailed analysis with the modified K-HRA was performed. It is expected that the HRA procedure suggested in this paper will be utilized for fire PSA for domestic NPPs as it is the first attempt to establish an HRA process considering fire effects.

Cervical cancer screening strategies based on stochastic process (확률모형을 이용한 자궁경부암 조기검진 전략)

  • Phee, Young-Gyu;Lee, Jeong-Hee;Jeong, Seong-Hwa
    • Journal of the Korean Data and Information Science Society
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    • v.21 no.1
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    • pp.129-138
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    • 2010
  • The purpose of this study was to investigate the most cost-effectiveness screening strategies for cervical cancer in Korea. We calculated the age-specific cervical cancer incidence rate from Korea Central Cancer Registry (2003), and then estimated the schedule sensitivity, detection probability, and screening and confirmative costs of each screening strategy based on the stochastic process (Lee and Zelen, 1998). The efficiency of the screening strategy was evaluated by incremental cost-effectiveness analysis. The most effective strategy was every 3 years pap smear test between the age of 35 and 65 years in the cervical cancer screening. The findings of this study will be helpful to evaluate efficiency of cancer screening strategies, and to provide the theoretical background of development and assessment of early detection of cancer in Korea.

Factors Affecting Breast Cancer Screening Behavior in Japan - Assessment using the Health Belief Model and Conjoint Analysis

  • Tsunematsu, Miwako;Kawasaki, Hiromi;Masuoka, Yuko;Kakehashi, Masayuki
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.6041-6048
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    • 2013
  • Background: Japanese women in their 40s or older have been encouraged to attend breast cancer screening. However, the breast cancer screening rate in Japan is not as high as in Europe and the United States. The aim of this study was to identify psychological and personal characteristics of women concerning their participation in breast cancer screening using the Health Belief Model (HBM). In addition, the attributes of screening more easily accepted by participants were analyzed by conjoint analysis. Materials and Methods: In this cross sectional study of 3,200 age 20-69 women, data were collected by an anonymous questionnaire. Questions were based on HBM and personal characteristics, and included attitudes on hypothetical screening attributes. Data of women aged 40-69 were analyzed by logistic regression and conjoint analysis to clarify the factors affecting their participation in breast cancer screening. Results: Among responses collected from 1,280 women of age 20-69, the replies of 993 women of age 40-69 were used in the analysis. Regarding the psychological characteristics based on HBM, the odds ratios were significantly higher in "importance of cancer screening" (95%CI: 1.21-2.47) and "benefits of cancer screening" (95%CI: 1.09-2.49), whereas the odds ratio was significantly lower in "barriers to participation before cancer screening" (95%CI: 0.27-0.51). Conjoint analysis revealed that the respondents, overall, preferred screening to be low cost and by female staff members. Furthermore, it was also clarified that attributes of screening dominant in decision-making were influenced by the employment status and the type of medical insurance of the women. Conclusions: In order to increase participation in breast cancer screening, it is necessary to disseminate accurate knowledge on cancer screening and to reduce barriers to participation. In addition, the attributes of screening more easily accepted were inexpensive, provided by female staff, executed in a hospital and finished in a short time.

Assessment of retinopathy of prematurity (ROP) revisited (최근 재증가하고 있는 미숙아망막병증의 임상 고찰)

  • Kim, Jeong Hun;Yu, Young Suk
    • Clinical and Experimental Pediatrics
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    • v.52 no.1
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    • pp.22-27
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    • 2009
  • Retinopathy of prematurity (ROP) is a major cause of blindness that affects premature infants. With advances in neonatology, ROP is likely to emerge as the most serious problem of vision loss in children even in developed countries; such a situation could be called the third epidemic of ROP. However, controversy and uncertainty still surround favorable outcomes of ROP. For successfully controlling ROP, timely and accurate screening is crucial because early treatment leads to favorable outcomes. Standard guidelines, including ROP classification, have provided satisfactory instructions for the screening and treatment of ROP. To improve the structural and functional outcomes of ROP, optimizing the timing of surgical interventions including cryotherapy, laser-photocoagulation, encircling, and vitrectomy is essential; these interventions can prevent the sequelae of ROP. It is essential for the neonatologist and the ophthalmologist to cooperate extensively for the successful treatment of ROP.

A Study of Contingency Screening Method for Voltage Security Analysis. (전압안전도해석을 위한 상정사고스크린닝에 관한 연구)

  • Song, Kil-Yeong;Kim, Yeong-Han;Choi, Sang-Geu
    • Proceedings of the KIEE Conference
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    • 1988.07a
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    • pp.879-882
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    • 1988
  • This paper describes a fast security analysis techique for voltage security assessment. The new method identifies the location of buses with potential voltage problems and thereby defines a voltage-sensitive subnetwork for contingency screening. The efficieny of this method is derived from the use of a voltage subnetwork to drastically reduce the number of bus voltages to be solved; and subsequently from the use of compensation techniques and sparse-vectors methods for screening. Results demonstrating the effectiveness of the method on the IEEE-14 bus model system are presented.

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Standardization of the Korean Child Development Inventory (K-CDI 아동발달검사 표준화 연구)

  • Kim, Jeong-Mee;Shin, Hee-Sun
    • Korean Journal of Child Studies
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    • v.27 no.4
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    • pp.39-53
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    • 2006
  • The Korean version of the Child Development Inventory (K-CDI) is a developmental screening test for children functioning in the one-six year range. Based on parent-report, the inventory assesses child developmental functioning in the areas of social, self-help, gross motor, fine motor, expressive language, language comprehension, letter and number skills, general development, and various symptoms and behavior problems. Participants were recruited from childcare centers and private groups and finally 1,143 children and their mothers from 4 locations nationwide participated in this study. Through analysis of item response rate of 270 items in 9 areas, new norm was formed. Reliability determined by internal consistency were relatively high (Cronbach ${\alpha}=.95$). Intercorrelations among sub-scales (range: .49-.96) indicated the construct validity, and the correlation between K-CDI and other screening tests supported the concurrent validity.

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Assessment of Motor Control Ability (운동조절능력의 평가)

  • Hwang, Seong-Soo;Hong, Wan-Sung
    • Journal of Korean Physical Therapy Science
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    • v.2 no.4
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    • pp.823-833
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    • 1995
  • The purposes of this review are that 1) what is the the concept of motor control, 2) what is the content of motor control assessment, and 3) which instruments or scales are used in clinical setting. Motor control is defined broadly the control of both movement and posture. And motor control focuses on understanding the control of movement already acquired. The purposes of assessment are screening, placement to apprpriate treatment program, program plan, evaluation, and progress assessment for individuals. The content of motor control assessment is included not only fexibility, tone, reflex & reaction, muscle strength, movement pattern, balance, gait, and functional ability, but also cognition, arousal, sensation, and perception. There ars many kinds of instruments or scales for assessing motor ability. Most of materials are tested the validity and reliability. But Korea has not own instrument for assessing motor ability. Therefore, Korea needs to develop the assessing tools for motor ability.

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