• 제목/요약/키워드: screening assessment

검색결과 609건 처리시간 0.031초

미꾸리의 생물지표를 이용한 농업지역의 수생태계 건강성 스크리닝 평가(사례연구) (The Ecological Health Screening Assessment of Agricultural area using Biomarkers and Bioindicators in Misgurnus Anguillicaudatus (case study))

  • 김자현;한선영;염동혁
    • 농약과학회지
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    • 제16권1호
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    • pp.62-68
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    • 2012
  • 본 연구에서는 내분비계 장애물질의 영향 및 생태계 건강성의 스크리닝 평가를 위해 미꾸리를 지표종으로 선정하여 대조지점(RA)과 농업지점(AS)에서 biomarker 4가지 항목과 bioindicator 4가지 항목을 포함하여 총 8가지 항목의 생물지표를 분석하였다. 생태계 건강성 평가를 위한 생물지표의 분석 결과 독성 화학물질의 영향을 나타내는 ethoxyresorufin-O-deethylase(EROD), acetylcholinesterase(AChE) 및 DNA damage 등의 생화학적 생물지표는 대조지점(RA)에 비해 유의한 차이가 있는 것으로 나타났다. 반면, 내분비계 장애물질의 영향을 반영하는 vitellogenin(VTG)는 농업지점(AS)에서 유의한 차이를 보이지 않았고, 개체수준의 생물지표(condition factor (CF), hepato-somatic index (HSI), gonado-somatic index (GSI)) 또한 유의한 차이를 보이지 않았다. 따라서 농업지점(AS)의 생태계 건강성은 내분비계 장애물질에 의한 영향은 미비한 것으로 판단되었으나, 농약, 중금속 등과 같은 독성을 보이는 화학물질이나 농업 지역의 특수성에 따른 서식지 환경 조건에 의해 일부 영향을 받은 것으로 사료되었다. 본 연구는 생화학적 생물지표와 개체수준의 생물지표를 이용한 스크리닝 평가로서 농업지역에 대한 종합적인 생태계 건강성 평가를 위해서는 생물지표 적용 항목을 확대하고, 개체군이나 군집 수준의 분석이 추가적으로 적용 되어야 하며 수생태계 내의 추정 오염물질에 대한 분석이 필요할 것으로 사료된다.

APR1400 종합진동평가를 위한 배관시스템의 유동유발진동 간이평가 (Screening Method for Flow-induced Vibration of Piping Systems for APR1400 Comprehensive Vibration Assessment Program)

  • 고도영;김동학
    • 한국소음진동공학회논문집
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    • 제25권9호
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    • pp.599-605
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    • 2015
  • U.S. Nuclear Regulatory Commission(NRC), Regulatory Guide(RG) 1.20(Rev.3, 2007년)은 원자로 냉각재계통, 주증기, 주급수 및 복수시스템의 주요 배관 및 기기에 대하여 압력변동 및 진동에 의한 잠재적 유해효과에 대한 평가를 요구한다. 그러나 증기발생기와 연결된 주증기, 주급수 및 복수시스템의 주요 배관 전체에 대하여 상세 해석하는 것은 매우 복잡하여 한계가 있다. 이 논문은 APR1400 원전의 종합진동평가(comprehensive vibration assessment program, CVAP)를 수행하기 위하여 증기발생기에 연결된 2차측 주요 배관의 음향공진과 펌프유발진동을 위한 간이평가 방법에 관한 것이다. 이 논문에서는 이러한 배관시스템의 잠재적 진동 원인이 무엇인지, 음향공진과 펌프유발진동의 가능성을 예방하기 위한 간이평가 방법은 무엇인지를 고찰하고자 한다. 이 논문은 APR1400 원전 증기발생기와 연결된 주증기 및 주급수 배관의 유동유발진동 간이평가를 위해 사용될 것으로 판단된다.

국내 전출력 원전 적용 화재 인간신뢰도분석 절차 개발 (Development of a Fire Human Reliability Analysis Procedure for Full Power Operation of the Korean Nuclear Power Plants)

  • 최선영;강대일
    • 한국안전학회지
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    • 제35권1호
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    • pp.87-96
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    • 2020
  • The purpose of this paper is to develop a fire HRA (Human Reliability Analysis) procedure for full power operation of domestic NPPs (Nuclear Power Plants). For the development of fire HRA procedure, the recent research results of NUREG-1921 in an effort to meet the requirements of the ASME/ANS PRA Standard were reviewed. The K-HRA method, a standard method for HRA of a domestic level 1 PSA (Probabilistic Safety Assessment) and fire related procedures in domestic NPPs were reviewed. Based on the review, a procedure for the fire HRA required for a domestic fire PSA based on the K-HRA method was developed. To this end, HRA issues such as new operator actions required in the event of a fire and complexity of fire situations were considered. Based on the four kinds of HFE (Human Failure Event) developed for a fire HRA in this research, a qualitative analysis such as feasibility evaluation was suggested. And also a quantitative analysis process which consists of screening analysis and detailed analysis was proposed. For the qualitative analysis, a screening analysis by NUREG-1921 was used. In this research, the screening criteria for the screening analysis was modified to reduce vague description and to reflect recent experimental results. For a detailed analysis, the K-HRA method and scoping analysis by NUREG-1921 were adopted. To apply K-HRA to fire HRA for quantification, efforts to modify PSFs (Performance Shaping Factors) of K-HRA to reflect fire situation and effects were made. For example, an absence of STA (Shift Technical Advisor) to command a fire brigade at a fire area is considered and the absence time should be reflected for a HEP (Human Error Probability) quantification. Based on the fire HRA procedure developed in this paper, a case study for HEP quantification such as a screening analysis and detailed analysis with the modified K-HRA was performed. It is expected that the HRA procedure suggested in this paper will be utilized for fire PSA for domestic NPPs as it is the first attempt to establish an HRA process considering fire effects.

확률모형을 이용한 자궁경부암 조기검진 전략 (Cervical cancer screening strategies based on stochastic process)

  • 피영규;이정희;정성화
    • Journal of the Korean Data and Information Science Society
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    • 제21권1호
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    • pp.129-138
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    • 2010
  • 본 논문에서는 우리나라 자궁경부암 조기검진 권고안을 바탕으로 검진주기 및 검진연령 변화에 따른 다양한 검진전략들의 효율성을 검토하고 비용-효과분석을 통하여 비용-효과적인 대안을 찾아 제시하고자 하였다. 한국중앙암등록본부의 2002년 자료와 확률모형을 이용하여 고려된 검진전략을 검진의 민감도와 무증상 상태에 있는 암 환자를 발견할 확률 및 검진비용을 추정하여 비용-효과분석을 시행하였다. 연구결과 비용-효과적인 측면에서 자궁경부세포검사를 이용한 35세부터 65세까지 3년 주기의 검진전략이 상대적으로 높은 효율성을 나타내었다.

Factors Affecting Breast Cancer Screening Behavior in Japan - Assessment using the Health Belief Model and Conjoint Analysis

  • Tsunematsu, Miwako;Kawasaki, Hiromi;Masuoka, Yuko;Kakehashi, Masayuki
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권10호
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    • pp.6041-6048
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    • 2013
  • Background: Japanese women in their 40s or older have been encouraged to attend breast cancer screening. However, the breast cancer screening rate in Japan is not as high as in Europe and the United States. The aim of this study was to identify psychological and personal characteristics of women concerning their participation in breast cancer screening using the Health Belief Model (HBM). In addition, the attributes of screening more easily accepted by participants were analyzed by conjoint analysis. Materials and Methods: In this cross sectional study of 3,200 age 20-69 women, data were collected by an anonymous questionnaire. Questions were based on HBM and personal characteristics, and included attitudes on hypothetical screening attributes. Data of women aged 40-69 were analyzed by logistic regression and conjoint analysis to clarify the factors affecting their participation in breast cancer screening. Results: Among responses collected from 1,280 women of age 20-69, the replies of 993 women of age 40-69 were used in the analysis. Regarding the psychological characteristics based on HBM, the odds ratios were significantly higher in "importance of cancer screening" (95%CI: 1.21-2.47) and "benefits of cancer screening" (95%CI: 1.09-2.49), whereas the odds ratio was significantly lower in "barriers to participation before cancer screening" (95%CI: 0.27-0.51). Conjoint analysis revealed that the respondents, overall, preferred screening to be low cost and by female staff members. Furthermore, it was also clarified that attributes of screening dominant in decision-making were influenced by the employment status and the type of medical insurance of the women. Conclusions: In order to increase participation in breast cancer screening, it is necessary to disseminate accurate knowledge on cancer screening and to reduce barriers to participation. In addition, the attributes of screening more easily accepted were inexpensive, provided by female staff, executed in a hospital and finished in a short time.

최근 재증가하고 있는 미숙아망막병증의 임상 고찰 (Assessment of retinopathy of prematurity (ROP) revisited)

  • 김정훈;유영석
    • Clinical and Experimental Pediatrics
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    • 제52권1호
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    • pp.22-27
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    • 2009
  • Retinopathy of prematurity (ROP) is a major cause of blindness that affects premature infants. With advances in neonatology, ROP is likely to emerge as the most serious problem of vision loss in children even in developed countries; such a situation could be called the third epidemic of ROP. However, controversy and uncertainty still surround favorable outcomes of ROP. For successfully controlling ROP, timely and accurate screening is crucial because early treatment leads to favorable outcomes. Standard guidelines, including ROP classification, have provided satisfactory instructions for the screening and treatment of ROP. To improve the structural and functional outcomes of ROP, optimizing the timing of surgical interventions including cryotherapy, laser-photocoagulation, encircling, and vitrectomy is essential; these interventions can prevent the sequelae of ROP. It is essential for the neonatologist and the ophthalmologist to cooperate extensively for the successful treatment of ROP.

전압안전도해석을 위한 상정사고스크린닝에 관한 연구 (A Study of Contingency Screening Method for Voltage Security Analysis.)

  • 송길영;김영한;최상규
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1988년도 전기.전자공학 학술대회 논문집
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    • pp.879-882
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    • 1988
  • This paper describes a fast security analysis techique for voltage security assessment. The new method identifies the location of buses with potential voltage problems and thereby defines a voltage-sensitive subnetwork for contingency screening. The efficieny of this method is derived from the use of a voltage subnetwork to drastically reduce the number of bus voltages to be solved; and subsequently from the use of compensation techniques and sparse-vectors methods for screening. Results demonstrating the effectiveness of the method on the IEEE-14 bus model system are presented.

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K-CDI 아동발달검사 표준화 연구 (Standardization of the Korean Child Development Inventory)

  • 김정미;신희선
    • 아동학회지
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    • 제27권4호
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    • pp.39-53
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    • 2006
  • The Korean version of the Child Development Inventory (K-CDI) is a developmental screening test for children functioning in the one-six year range. Based on parent-report, the inventory assesses child developmental functioning in the areas of social, self-help, gross motor, fine motor, expressive language, language comprehension, letter and number skills, general development, and various symptoms and behavior problems. Participants were recruited from childcare centers and private groups and finally 1,143 children and their mothers from 4 locations nationwide participated in this study. Through analysis of item response rate of 270 items in 9 areas, new norm was formed. Reliability determined by internal consistency were relatively high (Cronbach ${\alpha}=.95$). Intercorrelations among sub-scales (range: .49-.96) indicated the construct validity, and the correlation between K-CDI and other screening tests supported the concurrent validity.

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운동조절능력의 평가 (Assessment of Motor Control Ability)

  • 황성수;홍완성
    • 대한물리치료과학회지
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    • 제2권4호
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    • pp.823-833
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    • 1995
  • The purposes of this review are that 1) what is the the concept of motor control, 2) what is the content of motor control assessment, and 3) which instruments or scales are used in clinical setting. Motor control is defined broadly the control of both movement and posture. And motor control focuses on understanding the control of movement already acquired. The purposes of assessment are screening, placement to apprpriate treatment program, program plan, evaluation, and progress assessment for individuals. The content of motor control assessment is included not only fexibility, tone, reflex & reaction, muscle strength, movement pattern, balance, gait, and functional ability, but also cognition, arousal, sensation, and perception. There ars many kinds of instruments or scales for assessing motor ability. Most of materials are tested the validity and reliability. But Korea has not own instrument for assessing motor ability. Therefore, Korea needs to develop the assessing tools for motor ability.

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