• Title/Summary/Keyword: scientific discovery

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A pilot application study of densitometric image analysis as a potential comparative evaluation method for visualized fingerprints

  • Kim, Eun-Ji;Kim, Soo-Kyung;Seo, Kyung-Suk;Choi, Sung-Woon
    • Analytical Science and Technology
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    • v.33 no.4
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    • pp.197-207
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    • 2020
  • The current comparison methods with scoring systems that are used to compare visualized latent fingerprints (LF) have disadvantages. Evaluators using these methods are prone to make errors and fail to discriminate LFs correctly to notice the differences among those LFs. Therefore, a comparative and quantitative evaluation method that is capable of obtaining more objective and quantitative results is needed. Densitometric image analysis (DIA) is used in other fields as a reliable semi-quantitative comparison method. To apply DIA to LFs, the potential variables that can occur during the DIA process were tested. The visualized ridges of LFs can be compared using the concentration of dots against the background to make it possible to analyze the ridges with DIA. The variables that can be present during the DIA process include the thickness of the analysis line, the number of ridges to be taken, the number of divided zones within each of the fingerprints, and the angles of the analysis line against the ridge lines that were selected. From the analysis of the inked fingerprints and circular lines that are similar to fingerprints, the angle of the analysis lines with the ridge line was the most significant variable. The preliminary test result was applied to the comparison of LFs that were developed with the powder method and then compared with the AFIS analysis. A similar trend was found, and a more detailed and semi-quantitative comparison of the visualized LFs was possible. In the future, it is necessary to check the evaluative ability of the DIA method by analyzing the visualized LFs with other various development methods. However, DIA is currently an option that can be used as an objective comparative evaluation method during fingerprint studies with supplementary role.

Development and Validation of Visual Representation Competence Taxonomy (과학 교수 학습을 위한 시각적 표상 능력의 교육목표 분류체계 개발 및 타당화)

  • Yoon, Hye-Gyoung
    • Journal of The Korean Association For Science Education
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    • v.38 no.2
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    • pp.161-170
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    • 2018
  • Various forms of visual representations enable scientific discovery and scientific reasoning when scientists conduct research. Similarly, in science education, visual representations are important as a means to promote students' understanding of science concepts and scientific thinking skills. To provide a framework that could facilitate the effective use of visual representations in science classroom and systemic science education research, a visual representation competence taxonomy (VRC-T) was developed in this study. VRC-T includes two dimensions: the type of visual representation, and the cognitive process of visual representation. The initial categories for each dimension were developed based on literature review. Then validation and revision was made by conducting teachers' workshop and survey to experts. The types of visual representations were grouped into 3 categories (descriptive, procedural, and explanative representations) and the cognitive processes were grouped into 3 categories (interpretation, integration, and construction). The sub categories of each dimension and the validation process would be explained in detail.

Preliminary Evaluation of the in vitro Efficacy of 1, 2-di (Quinazolin-4-yl) Diselane against SiHa Cervical Cancer Cells

  • Huang, Yin-Jiu;Zhang, Yu-Yuan;Liu, Gang;Tang, Jie;Hu, Jian-Guo;Feng, Zhen-Zhong;Liu, Fang;Wang, Qi-Yi;Li, Dan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6301-6306
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    • 2014
  • Cervical cancer is one the most common malignancies among females. In recent years, its incidence rate has shown a rising trend in some countries so that development of anticancer drugs for cervical cancer is an urgent priority. In our recent anticancer drug discovery screen, 1, 2-di (quinazolin-4-yl)diselane (LG003) was found to possess wide spectrum anticancer efficacy. In the present work, the in vitro anticancer activity of LG003 was evaluated in the SiHa cervical cancer cell line. Compared with commercial anticancer drugs 10-hydroxycamptothecin, epirubicin hydrochloride, taxol and oxaliplatin, LG003 showed better anticancer activity. Furthermore, inhibition effects were time- and dose-dependent. Morphological observation exhibited LG003 treatment results in apoptosis like shrinking and blebbing, and cell membrane damage. Lactate dehydrogenase release assay revealed that LG003 exerts such effects in SiHa cells through a physiology pathway rather than cytotoxicity, which suggests that title compound LG003 can be a potential candidate agent for cervical cancer.

Gravitational-wave detection - for the new age of astronomy (중력파 검출 - 새로운 천문학의 시대를 위하여)

  • Oh, John J.
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.1
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    • pp.58.1-58.1
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    • 2015
  • Gravitational-wave has been predicted by Einstein's general relativity in 1916, but its direct detection has failed to date despite of the persistent efforts in the last fifty years in the ground-based gravitational wave detectors. In the centennial year of the birth of general relativity, 'advanced LIGO', one of the most promising Earth-based gravitational wave detectors, plans to start commissioning for the successful discovery of gravitational waves. In addition, a pathfinder satellite of eLISA project, a space-based GW antenna by European Space Agency (ESA), will be launched in the mid of this year. In this talk, we review the current status of gravitational waves detection experiments and discuss its scientific impacts and the possibility of opening the new age of astronomy.

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Multiple testing and its applications in high-dimension (고차원자료에서의 다중검정의 활용)

  • Jang, Woncheol
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.5
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    • pp.1063-1076
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    • 2013
  • The power of modern technology is opening a new era of big data. The size of the datasets affords us the opportunity to answer many open scientific questions but also presents some interesting challenges. High-dimensional data such as microarray are common in big data. In this paper, we give an overview of recent development of multiple testing including global and simultaneous testing and its applications to high-dimensional data.

An Analytical Review on Fatigue of Cancer Patients (암 환자의 피로에 관한 문헌 분석)

  • 이윤정;김달숙
    • Journal of Korean Academy of Nursing
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    • v.32 no.6
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    • pp.897-905
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    • 2002
  • The purpose of this study was to discuss and address the state of the knowledge development and the nature of knowledge regarding fatigue. Method: This study analyzed the 63 fatigue related articles published from 1990 to 2001. The analysis schema was 'Alternative linkages among philosophy, theory, and method for nursing science' (Kim, 1993). Result: The 63 articles had been studied only within 5 types among all 96 types of linkages. Most of the articles (59 among 63 articles) had been studied within scientific realism and deductive logic. Fifty-three articles among 59 articles were the type of explanatory and predictive theory, grasping reality by the etic method on the controlled setting. Conclusion: This study suggests more development of knowledge regarding fatigue with various logics, especially with discovery logic such as inductive and retroductive or methods in multiple designs on various subjects under various philosophy needed for nursing practice.

Emerging Frontiers of Graphene in Biomedicine

  • Byun, Jonghoe
    • Journal of Microbiology and Biotechnology
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    • v.25 no.2
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    • pp.145-151
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    • 2015
  • Graphene is a next-generation biomaterial with increasing biomedical applicability. As a new class of one-atom-thick nanosheets, it is a true two-dimensional honeycomb network nanomaterial that attracts interest in various scientific fields and is rapidly becoming the most widely studied carbon-based material. Since its discovery in 2004, its unique optical, mechanical, electronic, thermal, and magnetic properties are the basis of exploration of the potential applicability of graphene. Graphene materials, such as graphene oxide and its reduced form, are studied extensively in the biotechnology arena owing to their multivalent functionalization and efficient surface loading with various biomolecules. This review provides a brief summary of the recent progress in graphene and graphene oxide biological research together with current findings to spark novel applications in biomedicine. Graphene-based applications are progressively developing; hence, the opportunities and challenges of this rapidly growing field are discussed together with the versatility of these multifaceted materials.

RESULTS FROM THE YOHKOH SATELLITE

  • WATANABE TETSUYA
    • Journal of The Korean Astronomical Society
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    • v.29 no.spc1
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    • pp.291-294
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    • 1996
  • The .Japanese sun observing satellite, Yohkoh, has been operational for five years and her scientific instruments are still in good condition. They have revealed ample of evidences that solar flares were triggered by magnetic reconnection, which was, for the first time, clearly indicated to take place in the solar corona. Cusp structures in soft X-rays and a new type of hard X-ray sources at the top of flaring loops have strongly supported the scenario originally proposed by C-S-H-KP. Nonthermal energy input in hard X-rays and thermal energy estimated from soft X-rays are fundamentally consistent with the interpretation of thick-target and chromospheric-evaporation models (Neupert effect). X-ray jets, another discovery of Yohkoh, were also associated with magnetic reconnection, as a result of the interaction of emerging fluxes with pre-existing coronal loops. Temperature structures of active regions, quiet sun, and coronal holes had very dynamic differential-emission-measure (DEM) distributions and high-temperature tails of DEM were considered to come from the contribution of flare-like activity.

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Performance of CQUEAN camera

  • Choi, Chang-Su;Park, Won-Kee;Jeon, Yi-Seul;Pak, Soo-Jong;Im, Myung-Shin
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.2
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    • pp.63.1-63.1
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    • 2010
  • CQUEAN (Camera for QUasars in EArly uNiverse) is a newly developed camera system by CEOU optimized at 0.8 - $1.1{\mu}m$ wavelength region. From Aug. 10 to Aug. 17, 2010, the camera was installed at 2.1m Otto Struve telescope at McDonald Observatory, USA, and engineering test observation was performed. We obtained the data for the characteristics of camera and scientific purpose using 7 filters (g, r, i, z, Is, Iz, Y). For the purpose of discovery of z - 5~6 quasar, we specially used new filters (Is,Iz). During the test observation, we obtained the data of Gamma-Ray Burst, high redshift quasars, high redshift quasar candidates and other calibration data. We present general characteristics of the reduced data taken with CQUEAN and show the performance of the camera.

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A Study on the Blending Color in Karim Rashid's Works (카림 라시드의 작품에 나타난 블렌딩 색채에 관한 연구)

  • Kim, Sun-Young
    • Korean Institute of Interior Design Journal
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    • v.20 no.4
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    • pp.155-162
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    • 2011
  • In order to pursue the traces of truth, boundaries set by man for convenience were crossed or Integrated leading to the discovery of new paradigms. Such phenomena including collaboration, convergence, crossover and etc. are expressed in various forms across the society and culture. In particular, development of digital technology is moving away from its previous color based on scientific, statistical and quantitative perspective by using diverse variables. Also, as the borderlines of genres become increasingly more ambiguous, various concepts of color blending developed rapidly. Thus These chaosmos-like color blending have created new contents. This research aims to understand the principle of color blending in Karim Rashid's work, which advocates the world of design in diverse fields from industrial products to architecture. The principle of color blending such as information change, source color and destination color, interaction, and etc. makes it possible to extract the expressed element and method of color blending. Meanwhile, the features of color blending such as integrated space and time, vague form, and narrative genre can be inferred from case analysis.