• Biomolecules & Therapeutics
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• v.21 no.1
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• pp.72-78
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• 2013

This work aimed to assess some pharmacological activities of P. leptostachya var. asiatica Hara. The dried roots of P. leptostachya var. asiatica Hara were extracted with 70% ethanol to generate the powdered extract, named PLE. Anti-angiogenic activity was detected using chick chorioallantoic membrane (CAM) assay. In vitro anti-inflammatory activity was evaluated via analyzing nitric oxide (NO) content, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. Antioxidant activity was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay and reactive oxygen species (ROS) level in the stimulated macrophage cells. Matrix metalloproteinase-9 (MMP-9) and -2 (MMP-2) activities in the culture media were detected using zymography. PLE exhibits an anti-angiogenic activity in the CAM assay, and displays an inhibitory action on the generation of NO in the LPS-stimulated macrophage cells. In the stimulated macrophage cells, it is able to diminish the enhanced ROS level. It can potently scavenge the stable DPPH free radical. It suppresses the induction of iNOS and COX-2 and the enhanced MMP-9 activity in the stimulated macrophage cells. Both monooxygenase and oxidase activities of tyrosinase were strongly inhibited by PLE. Taken together, the dried roots of P. leptostachya var. asiatica Hara possess anti-angiogenic, anti-inflammatory, antioxidant and skin whitening activities, which might partly provide its therapeutic efficacy in traditional medicine.

• Economic and Environmental Geology
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• v.35 no.2
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• pp.149-154
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• 2002

Column tests were carried out to examine the effect of surfactant solution conditions on surfactant-enhanced remediation of contaminated soil. The selected conditions of the surfactant solution were concentration and pH. 1,2,4-trichlo-robenzene (TCB) was chosen as the model hydrophobic organic substances. Sodium diphenyl oxide disulfonate (DOSL) and octylphenoxypoly ethoxyethanol (OPEE) surfactants were selected for this study. Two Iowa soils, Fruitfield sand and Webster clay loam, were leached with surfactant solution. The test results revealed that an optimum condition was achieved for 4 %(v/v) of concentration and 10 of pH, respectively. The maximum recoveries of added TCB (93-98%) were obtained when optimal conditions of each surfactant solution parameter were simultaneously met. The optimum conditions of these parameters may be useful for surfactant-assisted remediation in soil contaminated by TCB.

• Journal of Korean Society for Geospatial Information Science
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• v.20 no.3
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• pp.91-99
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• 2012

Jinju city is operating by selecting 8 places as the flood inundation risk area and by designating shelters on this area targeting districts damaged by typhoon and heavy rain, in the past. This study selected the research area as Nabul district and Sangpyeong district where are located in the town and that has high population density out of districts with inundation risk. The network analysis of GIS was applied to the suitability assessment on location of shelter by calculating the moving speed and the arriving time after dividing it into children, general adults, and aged people in consideration of the evacuation condition in inundation disaster. As a result, it was indicated that optimal evacuation plan time for children and aged people exceeded in getting to the shelter because of evacuation time excess and that even general adults outrun the prescribed evacuation time in some districts. Accordingly, a problem for evacuation time was improved by additionally designating 1-2 shelters to existing shelters in Nabul and Sangpyeong districts. A countermeasure is needed to reduce life and property damage in disaster occurrence by implementing the evacuation warning and the age-based evacuation plan more specifically in the future.

• Journal of Korean Society for Geospatial Information Science
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• v.17 no.3
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• pp.41-48
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• 2009

This study investigated the characteristics of spatial expansion/centralization and the spatial structural change of urban. The data used in analysis were urban population, employment, building floor area, and land price. The analysis was performed for the data of 1995, 2000, and 2005 during 10 years after 1995. The method of research was as follows; The movement of mean center and standard distance/standard deviation ellipse was estimated to investigate the urban growth change. The result of Moran's I analysis showed a clustered pattern, not a dispersed pattern, however; the effect was not significant. The town area requires the well-ordered urban planning such as land use. The contours map demonstrates that a monopole structure was generally transformed into a multicentralization structure. The development of mutural connection axis among central street roads was fragile.

• Child Health Nursing Research
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• v.15 no.3
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• pp.271-281
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• 2009

Purpose: This study was conducted to develop an instrument to measure coping in emergency situations. Methods: The process included construction of a conceptual framework, generation 60 primary items, verification of construct validity and extraction of final items. The.60 preliminary items were reviewed for content validity by seven experts and were tested to evaluate inter-item correlation coefficient by three groups of elementary school students. From November 1 to December 10, 2008, data were collected from 920 elementary school students according to residential characters (major city, small town, rural area). Item analysis, factor analysis with rotation Varimax and Cronbach's alpha were used to analyze the data. Results: 1) There were 45 items in the final instrument categorized into 8 factors. 2) The factors were labeled as "Call for help and check" (8 items), "Care for common symptoms" (6 items), "Appropriate response for the situation" (5 items), "Evacuation" (6 items), "Care for tissue damage" (8 items), "Care for injury by heat, cold or foreign body" (6 items), "Offer help" (4 items) and "Rescue & escape" (2 items). 3) Cumulative percent of variance was 53.10% and eigen values ranged from 1.04 to 13.38. 4) Cronbach's alpha for the total was .943 and ranged from .527 to .869. Conclusion: Validity and reliability of the scale are confirmed in this study showing its utility for measuring coping in emergency situations with elementary school students. Utilization of the scale will also contribute to designing appropriate coping education programs for elementary school students.

• Journal of the Korean Institute of Rural Architecture
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• v.19 no.4
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• pp.57-65
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• 2017

Life quality in farming areas is declining these days on account of decrease in population with the outflow of young generations, advent of aging society, and also lack of social and physical infrastructure. To reverse this, the central and local governments have been devising policies in many ways; however, the vulnerable class in farming area suffering from financial difficulty is not supported with that properly. The results of applying insulation materials applicable to rural houses, EPS, e-board, and glass wool, actually to rural houses are summed as follows. EPS is the most inexpensive among the three installations in terms of material cost and expenses. The indoor and outdoor temperature difference increased from $0.9^{\circ}C$ to $2.5^{\circ}C$, and the temperature change reduced as $0.04^{\circ}C$. With e-board, the indoor and outdoor temperature difference increased from $3.3^{\circ}C$ to $7.5^{\circ}C$; however, the temperature change increased as $0.09^{\circ}C$. Unlike the other two methods, glass wool requires the additional installation of wooden frames. The material cost is highest, and the indoor and outdoor temperature difference increased from $1.1^{\circ}C$ to $8.0^{\circ}C$, and the temperature change reduced as $0.01^{\circ}C$. According to the results of measuring temperature, glass wool's temperature difference is measured to be the highest, but temperature change is found to be the most effective in EPS. Among the three insulation methods, EPS is the most economically advantageous as the material supply is easy and the cost is low. The material is easily processible, so ordinary town residents can install it easily, and it is effective at improving insulation performance, too. But this method cannot be applied when the house has walls that are not even. Also, as the insulator is thick, after the installation, the living space may be narrower as a result.

• Journal of Environmental Science International
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• v.29 no.5
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• pp.507-517
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• 2020

New towns and large multi-family housing complexes are being built in the capital region of Korea, with the goal of creating safe and pedestrian-friendly cities. Traffic accidents in such residential complexes, however, is on the rise, creating social problems. While there have been many previous studies on problems with pedestrian environment; there is a dearth of studies that take design-based approach to ensure safety in pedestrian environment within residential complexes. Therefore, this study aims to prevent traffic accidents by properly planning pedestrian environment within multi-family housing complexes, in addition to emphasizing theories related to planning safer pedestrian environment in general. This study found the following design directions required to improve the design theory of pedestrian safety in multi-family housing complexes: (1) Linking traffic facilities and residential complex spaces in Korea; (2) Considering implementation of United Kingdom road systems; (3) Establishing appropriate objectives for each residential complex based on case study. In response to these findings, the study selected the A84BL complex in Hwaseong Dongtan 2 Complex located in Dongtan-myeon, Hwaseong-si in Gyeonggi Province, Korea. Items that can be implemented, as well as spatial design directions, were discussed with a focus on private vehicles, pedestrians, and service vehicles.

• Korean Institute of Interior Design Journal
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• no.29
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• pp.281-288
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• 2001

It shows 21st century as a networking society that is moving up the concept of global town and being industrialized with regional and personal connections. Individual's original idea and variety of 21th century may be respected by such environmental change, and age (Literary, human axis, technology axis, nature axis, kaining farming axis are central keyword) of culture that cultural capacity of individual becomes important fetters that create added value is forecasted to become. The moaning for space that is unemployment enemy by change of conceptional environment about cultural life and agreeable quality of life by development of Information-Communication technology may be required newly. As it does interaction along with development of science technique and Information-Communication technology, the future environment of various that complex! Is predicted to form network environment (existence space, cyberspace) newly. Human central interest is risen in technology balance hereupon, and these characteristic escaped in physical system that do with functional special quality and require human central and sensitive interaction. First, if examine about phenomenon by Digitize and chance aspect that is risen in 21th century, Digitize is time that action occurs fusion Tuesday that is various and Blur phenomenon of city·space, and the period to collapse the border between several individual. Second, importance more than man-centered and sensitive aspect of functional physical system is risen by digital age with development of technology medium, and as the five digital senses showed up, it suggests a sensual of the times and therefore the interest and direction get set up for the sensual sides of consumers. Third, special quality is, medium enemy by that digital space connotes meaning disk floret, variability, transparency, space red of extensity etc.. to burn and is digitalised, can be risen by symbolic, original individualities and emotional communication's the importance is required sensitivity enemy who is sympathy horn by fusion anger of individual. Technology of new media may open direction of new communication through interface that did not enjoy so far is going to supply new means that can express own to human

• Journal of Navigation and Port Research
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• v.27 no.4
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• pp.375-381
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• 2003

The studies on automatic ship collision avoidance system, which have been carried out last 10 years, are facing on new situation due to newly developed high technology such as computer and other information system. It was almost impossible to make it used in real navigation 3-4 years ago because of the absence of the tool to get other ship's information, however recently developed technology suggests new possibility. This study is carried out to develop the algorithm of automatic ship collision support system. The NOMOTO ship's mathematic model is adopted in simulation for its simplicity. The fuzzy reason rules are used for course-keeping system and for the calculation of Collision Risk using TCPA/DCPA. Moreover ‘encounter type’ between two ships is analyzed based on Regulations for Preventing Collisions at Sea and collision avoidance action is suggested. Some situations are simulated to verity the developed algorithm and appropriate avoidance action is shown in the simulation.

• Journal of the Korean Geographical Society
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• v.38 no.2
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• pp.237-256
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• 2003

The main aim of this paper is to provide a plan for building an effective and competitive innovation system of Daeduck Valley in Korea through analysing the process of knowledge production and commercialisation of venture firms in the perspective of industry-(university) research networks. Since 1997, with the willingness of the government aimed at building' second Sillicon Valley', an ostensible innovation system cantered around the existing science technology town has been able to be built in Daeduck Valley. Nonetheless, some fundamental problems with the knowledge production and commercialisation of venture firms were appeared as the results of this study. It is led tv not only the lack of network agents and institutes that are able to facilitate and coordinate the networks of economic actors comprised of the innovation system, but also the impertinent roles of economic actors. In particular, these problems were differentiated in accordance with the growth stage of venture firms and the processes of knowledge production. Therefore, several policy implications for building innovation system are suggested in the perspective of the complement of existing innovation system of Daeduck, rather than constructing a new innovation system. At the same time, they are provided in accordance with different growth stages and knowledge production processes.