• 대한족부족관절학회지
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• 제22권1호
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• pp.38-43
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• 2018

Purpose: Treatment of diabetic foot infection due to methicillin-resistant Staphylococcus aureus (MRSA) remains challenging. Applying vancomycin-impregnated cement is one of the best methods of treatment. Vancomycin-impregnated cement has been used worldwide; however, to date, there is a limited number of studies regarding its use. We evaluated the duration of antimicrobial activity of vancomycin-impregnated cement stored at room temperature after manufacturing. Materials and Methods: The vancomycin-impregnated cement was manufactured by mixing 1 g of vancomycin with 40 g of polymer and adding 17.90 g of liquid monomer. The cement dough was shaped into flat cylinders with diameter and height of 6 mm and 2 mm, respectively. Another cement of the same shape without mixing vancomycin was prepared as the negative control. All manufactured cements were sterilized with ethylene oxide gas and stored at room temperature. Each cement was placed on Mueller Hinton agar plate lawned with standard MRSA strain. Standard vancomycin disk and gentamicin disk were placed together. After 24 hours, the diameter of inhibition zone was measured, and if the diameter was less than 15 mm, vancomycin-impregnated cement was regarded as a loss of antimicrobial activity. The study was repeated every 2 weeks until vancomycin-impregnated cements lost their antimicrobial activity. Results: Vancomycin-impregnated cement stored for a duration of 16 weeks created a 14 mm inhibition zone, while vancomycin disk created a 15 mm inhibition zone. Vancomycin-impregnated cement stored for a duration of 17 weeks created 7 mm and 9 mm inhibition zones, while vancomycin disk created 16 mm and 15 mm inhibition zones, respectively. Conclusion: We found a decrease of antimicrobial activity in vancomycin-impregnated cements after 16 weeks. After 17 weeks, they showed definite loss of antimicrobial activity. Therefore, we recommend not using vancomycin-impregnated cement spacers that has been stored for more than 16 weeks at room temperature.

• 한국물환경학회지
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• 제33권5호
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• pp.511-524
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• 2017

This study was carried out for the purpose of creating a restoration plan to improve the ecological quality of the Changwon and Nam streams. Based upon the results of comprehensive diagnostic assessment, restoration priority was given to the upstream reach, where conservation status is relatively superior. Restoration level was usually determined to practice active restoration as conservation, and the states of both Changwon and Nam streams were not so good. Restoration plans, by reach, were classified into "upstream", "midstream", and "downstream" were suggested in both terms of horizontal section frame and vegetation-based on the result of diagnostic assessment and the reference information. "Upstream", "mid-stream" and the "downstream" of Changwon and Nam streams were classified into "small-gravel- mountainous", "small-sand-plain", and "small-clay-plain streams" respectively (based on scale, and substrate and slope of river bed). The spatial arrangement of vegetation was laid out in diagram form by reflecting micro-topography and the water level of the horizontal section of river. Information regarding species composition was recommended as dominant species, which appear frequently in three vegetation zones composed of herbaceous plants, shrubs and trees and sub-tree- dominated zones divided by reflecting disturbance regime, depending on position on the horizontal section of river. Moreover, there have been prepared not only plans to improve the terrestrial ecosystems around the streams but also plans to create ecological networks, which can serve to improve the ecologic quality of the whole regional environment by serving to connect streams and terrestrial ecosystems, a process probably necessary and definitely recommended to realize true (genuine) restoration. Plans for ecological parks and networks were prepared by mimicking the species composition of Alnus japanica community, Zelkova serrata community, Carpinus laxiflora community, Quercus aliena community, and Q. serrata community.

• 한국콘텐츠학회논문지
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• 제21권11호
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• pp.213-223
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• 2021

어린이는 행동적, 신체적 특성상 성인보다 교통사고에 노출될 가능성이 높기 때문에 안전한 보행환경을 조성하는 것은 매우 중요하다. 이에 이 연구에서는 교통사고분석시스템(TAAS)에서 제공하는 2016-2018년 서울시 보행자 교통사고 자료로 공간포아송 모형을 활용하여 어린이보호구역 주변 보행자 교통사고에 영향을 미치는 도로 및 교통안전시설의 특성을 분석했다. 주요 분석 결과는 다음과 같다. 첫째, 어린이보호구역 내 교차로가 많고 근린도로 비율이 높을수록 보행자 교통사고 발생 위험이 높아진다. 둘째, 보행자 작동신호기는 보행자 교통사고 발생을 줄이는 것으로 나타났다. 셋째, 이 연구에서 고려한 교통안전시설 중 보행자 작동신호기를 제외하고는 어떠한 교통안전시설도 보행자 교통사고 위험을 줄이는 데 효과가 없는 것으로 나타났다. 한편, 물리적 시설의 개선뿐만 아니라 교통안전교육 등 비물리적 요인이 뒷받침 된다면 어린이보호구역 내 보행자 교통사고 감소 효과는 더욱 극대화될 것으로 기대된다.

• Radiation Oncology Journal
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• 제21권4호
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• pp.315-321
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• 2003

목적: 발육 중인 백서 태아 대뇌 피질에서 방사선조사에 의한 아포토시스 반응에 대하여 알아보고자 하였다 대상 및 방법: 임신 백서의 태령 17 내지 19일(E17$\~$E19)에 선형가속기의 X-ray를 이용하여 어미 쥐의 복부에 방사선을 조사하였다. 방사선량에 따른 아포토시스를 보기 위하여 1, 2, 3, 4 Gy를 전후 조사면으로 방사선조사를 시행하고 5시간 후 백서 태아의 뇌를 획득하였다. 시간 경과에 따른 아포토시스를 보기 위하여 E7$\~$E19에 2 Gy의 방사선을 조사한 후 1, 3, 6, 12, 24시간에 각각 백서 태아의 뇌를 획득하였다. 대조군은 방사선을 조사하지 않은 임신 쥐를 같은 조건하에서 사육하여 각 군당 3마리씩 할당하였다. 아포토시스 세포는 면역조직화학적 방법(TUNEL, In situ 707-mediated dUTP nick end labeling)으로 염색하여 관찰하였다 결과: 백서 태아 대뇌 피질에서 TUNEL 양성인 세포는 광학현미경하에서 전형적인 아포토시스의 형태학적 특징을 나타내었다 대조군에서는 대뇌 피질의 전 층에서 TUNEL 양성세포를 거의 발견할 수 없었다. 1 Gy의 방사선 조사 후 5시간에 대뇌피질 전 층에서 미약하게 관찰되었으나 2 Gy에는 전 층에서 1 Gy 경우보다 더 증가하였고 그중 뇌실대와 중간대에서 피질대보다 더 많이 나타났다. 조사된 1$\~$4 Gy 범위에서 방사선량이 증가할수록 TUNEL양성세포가 더욱 증가하는 것을 볼 수 있었다. 2 Gy의 방사선 조사 후 3시간부터 TUNEL양성세포가 관찰 되기 시작하여 방사선 조사 후 6시간에 최고점을 이루었으며 이는 24시간까지 지속되었다. 결론: 발육 중인 백서 태아 대뇌피질에서 방사선에 의한 아포토시스의 전형적인 형태학적 특징을 관찰할 수 있었다. 아포토시스는 뇌실대와 중간대에서 피질대보다 더 많이 나타났으며 이는 줄기세포와 초기의 분화세포에서 방사선조사에 대한 감수성이 더욱 민감함을 시사하였다.

• Steel and Composite Structures
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• 제29권3호
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• pp.333-348
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• 2018

An analytical method is developed for analysing the contact buckling response of infinitely long, thin corrugated plates and flat plates restrained by a Winkler tensionless foundation and subjected to linearly varying in-plane loadings, where the corrugated plates are modelled as orthotropic plates and the flat plates are modelled as isotropic plates. The critical step in the presented method is the explicit expression for the lateral buckling mode function, which is derived through using the energy method. Simply supported and clamped edges conditions on the unloaded edges are considered in this study. The acquired lateral deflection function is applied to the governing buckling equations to eliminate the lateral variable. Considering the boundary conditions and continuity conditions at the border line between the contact and non-contact zones, the buckling coefficients and the corresponding buckling modes are found. The analytical solution to the buckling coefficients is also expressed through a fitted approximate formula in terms of foundation stiffness, which is verified through previous studies and finite element (FE) method.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 춘계 학술발표회
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• pp.607-614
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• 2010

Shear behavior of granular soils largely affects the safety and stability of underground and earth structures. This study presents the characteristics of shear zone in a direct shear test using shear wave and electrical resistivity measurements. An innovative direct shear box made of transparent acrylic material has been developed to prevent direct electric current. Bender elements and electrical resistivity probe are embedded in the wall of direct shear box to estimate the shear wave velocities and the electrical resistivity at the shear and non-shear zones. Experimental results show that the void ratio and shear wave velocity at shear zone increase during shearing while the values remain constant at non-shear zone. The results demonstrate correlation among the contact force, small strain shear modulus, and void ratio at shear zone. This study suggests that the application of the modified direct shear box including shear wave and electrical resistivity measurements may become an effective tool for analyzing soil behavior at shear zone.

• Steel and Composite Structures
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• 제28권6호
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• pp.759-766
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• 2018

Friction Stir Welding (FSW) is a solid-state process, where the objects are joined together without reaching their melting point. It has been shown that this method is a suitable way to join dissimilar aluminium alloys. The current article employed hole drilling technique to measure the residual stress distribution experimentally in different zones of dissimilar aluminium alloys AA6061-T6 and AA7075-T6 Butt welded using FSW. Results are compared with those of similar AA6061-T6 plates joined using a conventional fusion welding method called tungsten inert gas (TIG). Also, the evolution of the residual stresses in the thickness direction was investigated, and it was found that the maximum residual stresses are below the yield strength of the material in the shoulder region. It was also revealed that the longitudinal residual stresses in the joint were much larger than the transverse residual stresses. Meanwhile, Vickers micro hardness measurements were performed in the cross-section of the samples. The largest hardness values were observed in the stir zone (SZ) adjacent to the advancing side whereas low hardness values were measured at the HAZ of both alloys and the SZ adjacent to the retreating side.

• 한국해양공학회:학술대회논문집
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• 한국해양공학회 2006년 창립20주년기념 정기학술대회 및 국제워크샵
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• pp.331-334
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• 2006

This paper deals with the ways how the AUV is composed of sub-modules to be fault-tolerant during the mission. The emergency situations can be classified into several parts according to the zones where the situations take place - sensor zone, actuator zone, interpreter zone, and communication zone. This paper explains how each element of emergency situation is detected, contained and treated, and as a result, introduce the modular structured AUV controller for the autonomous cruising.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
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• pp.679-681
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• 2003

The objectives of this research are as follows. First, to investigate methods for a national-scale land cover map based on multi-temporal classification of MODIS data and multi-spectral classification of Landsat TM data. Second, to investigate methods to p roduce ecological zone maps of Korea based on vegetation, climate, and topographic characteristics. The results of this research can be summarized as follows. First, NDVI and EVI of MODIS can be used to ecological mapping of the country by using monthly phenological characteris tics. Second, it was found that EVI is better than NDVI in terms of atmospheric correction and vegetation mapping of dense forests of the country. Third, several ecological zones of the country can be identified from the VI maps, but exact labeling requires much field works, and sufficient field data and macro-environmental data of the country. Finally, relationship between land cover types and natural environmental factors such as temperature, precipitation, elevation, and slope could be identified.

• Geomechanics and Engineering
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• 제29권6호
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• pp.627-643
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• 2022

Water-rock interactions have a significant influence on the mechanical behavior of rocks. In this study, uniaxial compression and tension tests on different water-treated sandstone samples were conducted. Acoustic emission (AE) monitoring and micro-pore structure detection were carried out. Water-rock interactions and their effects on rock mechanical behavior were discussed. The results indicate that water content significantly weakens rock mechanical strength. The sensitivity of the mechanical parameters to water treatment, from high to low, are Poisson ratio (𝜇), uniaxial tensile strength (UTS), uniaxial compressive strength (UCS), elastic modulus (E), and peak strain (𝜀). After water treatment, AE activities and the shear crack percentage are reduced, the angles between macro fractures and loading direction are minimized, the dynamic phenomenon during loading is weakened, and the failure mode changes from a mixed tensile-shear type to a tensile one. Due to the softening, lubrication, and water wedge effects in water-rock interactions, water content increases pore size, promotes crack development, and weakens micro-pore structures. Further damage of rocks in fractured and caved zones due to the water-rock interactions leads to an extra load on the adjoining coal and rock masses, which will increase the risk of dynamic disasters.