• Title/Summary/Keyword: sample production

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The Inhibitive Effects of Yukgunja-tang on the Cerebral Ischemia (대군자탕이 뇌허혈에 미치는 억제 효과)

  • Kim Hee Seong;Lee Sang Lock;Jeong Hyun Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.2
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    • pp.419-426
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    • 2004
  • This experimental study was designed to investigate the effects of Yukgunja-tang(YGJT) on the inhibition of cerebral ischemia in rats. And We measured regional cerebral blood f1ow(rCBF) and pial arterial diameter(PAD) in cerebral ischemic rats, and cytokines production in serum Of cerebral ischemic rats. The results were as follows; Both rCBF and PAD were significantly and stably increased by YGJT(10 mg/kg, i.p.) during the period of cerebral reperfusion, which contrasted with the findings of rapid and marked increase in control group. In cytokine production of serum by drawing from femoral arterial blood after middle cerebral arterial occlusion(MCAO) 1 hr, IL-1β and TGF-β production of sample group were similar to that of control group, but sample group was decreased TNF-α production compared with control group, and was significantly increased IL-10 production in compared with control group. In cytokine production of serum by drawing from femoral arterial blood after reperfusion 1 hr, sample group was significantly decreased IL-1β and TNF-α production compared with control group, but TGF-β production of sample group was similar to that of control group, and sample group was significantly increased IL-10 production compared with control group. In cytokine production of serum by drawing from femoral arterial blood after reperfusion 4 hrs, sample group was significantly decreased IL-1β production compared with control group, and sample group was decreased TNF-α production in compared with control group, but TGF-β production of sample group was similar to that of control group, and sample group was increased IL-10 production compared with control group. This results were suggested that YGJT has inhibitive effect on the brain damage by inhibited IL-1β production and TNF-α production, but accelerated IL-10 production. We thought that YGJT should have an anti-ischemic effect through the improvement of cerebral hemodynamics and inhibitive effect on the brain damage.

Mechanism of Palmul- Tang on the Change of Cerebral Hemodynamics in Rats (팔물탕이 뇌혈유력학 변화에 미치는 작용기전)

  • Park Cheol Hun;Kim Gye Yeop;Jeong Hyun Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.6
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    • pp.1714-1721
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    • 2004
  • This experimental study was designed to investigate the mechanism of Palmul-Tang(PMT) on the changes of cerebral hemodynamics in rats. The changes of cerebral hemodynamics in normal rats were as follows ; The PMT-induced increase in regional cerebral blood flow was significantly inhibited by pretreatment with indomethacin(1㎎/㎏, i.p.), an inhibitor of cyclooxygenase, and was inhibited by methylene blue(10㎍/㎏, i.p.), an inhibitor of guanylate cyclase. The PMT-induced dilation in pial arterial diameter was significantly inhibited by pretreatment with indomethacin and methylene blue. The PMT-induced increase in mean arterial blood pressure was significantly inhibited by pretreatment with indomethacin but was increased by methylene blue. This results were suggested that the mechanism of PMT was mediated by cyclooxygenase. The changes of cytokine production in cerebral ischemic rats were as follows ; In cytokine production of serum by drawing from femoral arterial blood after middle cerebral arterial occlusion 1hr, sample group was decreased IL-1β and TNF-α production compared with control group, IL-10 production of sample group was similar to that of control group, but sample group was significantly increased TGF-β production compared with control group. In cytokine production of serum by drawing from femoral arterial blood after reperfusion 1hr, sample group was significantly decreased IL-1β production compared with control group and decreased TNF-α production compared with control group. IL-10 production of sample group was similar to that of control group, but sample group was significantly increased TGF-β production compared with control group. In cytokine production of serum by drawing from femoral arterial blood after reperfusion 4 hrs, sample group was significantly decreased IL-1β production compared with control group, but IL-10 production of sample group was similar to that of control group. sample group was increased TNF-α and TGF-β production compared with control group. These results suggested that PMT had inhibitive effect on the brain damage by inhibiting IL-1β and TNF-α production, but by accelerating TGF-β production. The present author thought that PMT had an anti-ischemic effect through the improvement of cerebral hemodynamics and inhibitive effect on the brain damage.

The Study on NCS Development for the Production of Hanbok (한복생산 분야의 국가직무능력표준 개발에 관한 연구)

  • Suh, Seunghee;Kim, Jung-Sook
    • Journal of the Korean Society of Costume
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    • v.65 no.2
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    • pp.62-74
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    • 2015
  • The purpose of this research is to analyse the process of development and verification of 'National Competency Standards' of Hanbok production, which was carried out in 2013 for the fashion industry. As the result of this research, the definition of the duty in Hanbok production is 'to conduct a series of step-by-step processes of planning and developing fabric and design, then making pattern, cutting fabric and sewing.' The competency unit for Hanbok production is analyzed in 10 categories: analysis of market trends, design plan, production and manipulation of fabric, production process plan, sample making, pattern making, cutting out, sewing, finishing sewing, inspection of the product quality. Competency unit elements of each competency unit are as follows. 1) analysis of market trends: to research market trend resources, to analyse consumers' buying trend, to analyse industry changes, 2) design plan: to develop design, to plan fabrication, to draw flats, 3) production and manipulation of fabric: to develop fabric planning, to prepare fabric manipulation, to conduct fabric manipulation, 4) production process plan: to grasp design, to plan sewing method, to prepare a specification sheet, 5) sample making: to make a sample pattern, to cut sample fabrics, to sew sample, to finish sample making, 6) pattern making: to measure body, to make production pattern, to adjust production pattern, 7) cutting out: to care fabrics, to lay out patterns, to cut out fabrics, 8) sewing: to sew a garment, to sew a lining, to attach a lining, 9) finishing sewing: to neaten edges, to attach trims, to press to finish, 10) inspection of the product quality: to confirm correspondence with the specification sheet, to inspect appearance.

The Experimental Study of FOENICULI FRUCTUS on the Ischemic Cerebrovascular Disease (소회향이 허혈성 뇌혈관 질환에 미치는 실험적 연구)

  • Kim, Nam-Soon;Jeong, Hyun-Woo;Kang, Sung-Yung
    • Journal of Oriental Neuropsychiatry
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    • v.18 no.1
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    • pp.185-196
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    • 2007
  • Objective : This experimental Study was designed to investigate the effects of FOENICULI FRUCTUS(FF) on the change of inhibition lactate dehydrogenase(LDH) activity in neuronal cells and cytokines production in serum of cerebral ischemic rats. Method : FOENICULI FRUCTUS(FF)freeze dry powder and FF on the LDH activity in neuronal cells. Changes of FF on the physiological parameters(PaO2, PaCO2, MABP and HR) in crerbral ischemic rats. Effects of FF on the IL-1beta production, $TNF-{\alpha}$ production, $TGF-{\beta}$ production, and IL-10 in serum of cerebral ischemic rats. MCAO :. cytokines production of serum by drawing from femoral arterial blood after MCAO 1 hr. Reperfusion : cytokines production of serum by drawing from femoral arterial blood after reperfusion 1 hr. Results and Conclusion : 1. FF did not inhibit lactate dehydrogenase(LDH) activity in neuronal cells. 2. In serum by drawing from femoral arterial blood after middle cerebral arterial occlusion(MCAO) 1 hr and reperfusion 1 hr, sample group was significantly decreased $IL-l{\beta}$ production compared with control group 3. In serum by drawing from femoral arterial blood after MCAO 1 hr and reperfusion 1 hr, sample group was significantly decreased $TNF-{\alpha}$ production compared with control group. 4. In serum by drawing from femoral arterial blood after MCAO 1 hr and reperfusion 1 hr, sample group was significantly increased $TGF-{\beta}$ production compared with control group. 5. In serum by drawing from femoral arterial blood after reperfusion 1 hr, sample group was significantly increased IL-10 production compared with control group. This results were suggested that FF had inhibitive effect on the brain damage by inhibited LDH activity, $IL-l{\beta}$ and $TNF-{\alpha}$production, but accelerated $TGF-{\beta}$ production and IL-10 production.

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Production of Window Motor Assembly Parts in Automotive Body (자동차 전장에서 윈도우 모터 조립 부품의 생산)

  • Lee, Jeong-Ick
    • Journal of the Korea Convergence Society
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    • v.3 no.4
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    • pp.29-34
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    • 2012
  • Power window motor assembly including ECU system is important to doors of automobile. This study is done for own development instead of importing of power window motor assembly. This paper is written under five specific subjects. The first, making of prototype sample and analysis of mass-production problem using CAE, the second, design of mass-production mold(2D and 3D), the third, manufacturing of sample mold, the fourth, tryout and measuring of 3 dimensions, the fifth, data analysis and mold modify. In the among them, product sample and analysis of mass-production using CAE, design and manufacture of mass-production mold, and production of sample mold are successfully done. In the results, it is made clear that two cavity and one gate are proper to make a mold of power window motor assembly housing. Besides, it is acquired own technology for mass-production of power window motor.

Environmental Conditions and Resource Management in Smallholder Dairy Farms in Thailand. I. Production Systems and Management of Resources

  • Skunmun, P.;Boonsom, J.;Kaewsuwan, S.;Chantalakhana, C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.2
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    • pp.215-219
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    • 1999
  • This study aims to make detail examination of smallholder dairy farming systems in the Nongpho Dairy Cooperative. Forty-three dairy farms were selected from three geographical areas i.e. irrigated area, municipality area, and factory area. Within each area some number of sample farms were selected from each of the three levels of farm and animal crowdedness (very crowded, crowded, and not crowded farms). Detail data were collected during 1996 to 1997, they were socio-economic conditions of the sample farms and farmers, dairy production systems and management of resources (animals, bam, feeds, stocking rates, herd structure, animal body conditions, milk yield and milk quality, manure and farm wastes management, and other related items). Detail information useful for the improvement of farm production efficiency were discussed. It was very clear that much improvement of smallholder dairy production can be achieved if the recommendations given by this study were implemented.

Effect of Different Rice Treatments on Fermentation Characteristics of Baikhaju (a Korean Traditional Alcoholic Beverage) (백하주의 발효 특성에 대한 원료 쌀의 처리 효과)

  • Park, Wan-Soo;Kim, In-Ho;Koo, Young-Jo
    • Journal of the Korean Society of Food Culture
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    • v.11 no.5
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    • pp.601-608
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    • 1996
  • Fermentation characteristics of Baikhaju (a typical Korean traditional alcoholic beverage) were investigated during fermentation with differently treated rice samples, which were steamed rice (SR), plain steamed rice bread (RB), rice porridge (RP) and roasted rice (RR). The RB sample showed an excellent fermentation efficiency with the highest alcohol production (20.84%). The SR and RR samples showed 17.79% and 17.31% of alcohol production, respectively. The RP sample was the lowest alcohol production (11.47%). The pH values of all the beverage samples were similar and were ranged from 3.6 to 3.9. The fermentation periods of RB and RR samples were longer than the SR and RP. The inner temperature and microbial growth in all the beverages increased at each of input steps of the rice and Nuruk (a Korean-style bran koji). Fusel oil content of the SR and RP samples (613.6 ppm) was higher than that of RR (482.7 ppm). The RB sample with the best fermentation efficiency had the lowest fusel oil content (341.8 ppm). The RP sample showed the highest score in sensory evaluation and RB sample showed the lowest. The results on sensory evaluation were contrary to those on the fermentation efficiency.

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The Effects of Sugar Addition in Yogurt Prepared from Egg White Powder and Casein (난백분말과 카제인으로 만든 요구르트에서 당의 첨가 효과)

  • 고영태;이주원
    • Korean journal of food and cookery science
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    • v.12 no.2
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    • pp.153-161
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    • 1996
  • A curd yogurt was prepared from egg white powder (EWP) and casein added with sugars (glucose, fructose, lactose). The effects of sugar addition on acid production and growth of Lactobacillus were studied. The effects of sugar addition on sensory property and volatile aroma compounds were also studied. Acid production by L. acidophilus in EWP 2% (W/V), casein 3% (w/v) and sugar 0.5,1 or 2% W/V) was lower than that of L. acidophilus in milk (control). Acid production in sample added with glucose or fructose of 1% or 2% (W/V) was higher than that of 0.5% (W/V), while acid production in lactose added sample was not affected with the concentration of lactose. Number of viable cells of L. acidophilus at 24 hr in milk, glucose added sample, fructose added sample and lactose added sample was 3.6${\times}$10/Sup 9/, 5.6${\times}$10$\^$8/, 6.0${\times}$10$\^$8/,and 3.2${\times}$10$\^$7/, respectively. Through 30hr fermentation, acid production and number of viable cells of L. acidophilus in milk were higher than those of sugar added samples. Sensory property of fructose added sample was slightly better than that of milk yogurt (reference), while that of lactose added sample was significantly inferior. Though the composition of volatile aroma compounds was slightly different according to sample, gas chromatographic analysis detected acetone, ethanol, diacetyl and acetoin in samples fermented by L. acidophilus.

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Reuse of Yuza Seed By-product for Production of Aphicidal Rhamnolipid by Pseudomonas sp. EP-3 (Pseudomonas sp. EP-3 rhamnolipid 에 의한 진딧물 살충성 생산을 위한 유자씨앗 부산물의 재활용)

  • Lim, Da Jung;Park, Tae Hyun;Yang, Si Young;Kim, Jin Cheol;Kim, In Seon
    • Korean Journal of Environmental Agriculture
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    • v.36 no.1
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    • pp.36-42
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    • 2017
  • BACKGROUND: Yuza seed by-product has been produced in a large amount from the agricultural farms in the southern area of Korea. It has been mostly abandoned after commercial process for the production of juice, jam and tea. The study on the reuse of the yuza seed by-product has received much attention as a bio-resource material for the production of active compound in agriculture. METHODS AND RESULTS: Insecticidal rhamnolipid-producing Pseudomonas sp. EP-3 was grown in mineral salt media with the yuza seed by-product at 2, 20, 50 and 100 g/L. The growth of EP-3 was accompanied by a increase in insecticidal activity against green peach aphid. The highest insecticidal activity was observed when EP-3 was grown in the medium containing 50 g/L of the seed sample, producing approximately 996 mg/L of rhamnolipid at 96 h. Palmitic acid, stearic acid, oleic acid and linoleic acid were determined as the major fatty acids of the seed sample. The EP-3 cultures grown on the fatty acid mixture extracted from the seed sample showed a aphid mortality similar to that of cultures grown on the seed sample. The EP-3 cultures grown on 50 g/L of the seed sample showed aphid mortality more than 90% under greenhouse conditions. CONCLUSION: This study suggested that the yuza seed by-product may be used as a renewable material for microbial production of rhamnolipid against green peach aphid.