• 제목/요약/키워드: safety indicators

검색결과 483건 처리시간 0.028초

임상시험 전자자료 관리를 위한 평가 프레임웍 (A Performance Evaluation Framework for e-Clinical Data Management)

  • 이현주
    • 인터넷정보학회논문지
    • /
    • 제13권1호
    • /
    • pp.45-55
    • /
    • 2012
  • 임상시험 전체 소요시간 및 비용의 절감, 임상 데이터 질의 향상을 위해 임상시험 전자자료의 관리가 점차 중요해지고 있다. 또한 임상시험 전자자료 관리는 전자 임상시험의 안정성 및 질을 위해 규정 가이드라인을 준수하는 것이 결정적으로 필요하다. 본 연구는 전자적 시스템을 활용한 임상시험에 있어 데이터 관리의 성과를 평가하기 위한 프레임웍을 개발하고자 한다. 연구의 목적을 위해 임상시험 프로세스에 근거하여 기반능력, 연구설계, 연구진행 및 연구완료 등 네 개의 주요 메트릭을 구성함으로써 데이터 관리의 수준을 측정할 수 있는 성과척도를 도출한다. 이때 각 성과척도의 도출 기준은 임상시험 자체가 지향하는 데이터의 질 향상, 전자자료 관리 프로세스의 비용과 효율성 및 규정 준수 수준 등 네 가지의 관리적 관심을 기준으로 하며, 각 성과척도 별로 전자자료 관리 프로세스 상 실질적으로 측정 가능한 측정지표를 제시한다. 평가 프레임웍은 네 가지의 주요 측정 메트릭에 근거하여, 세 개의 데이터 영역(연구기관, 모니터링, 데이터관리센터) 별로 구성된다. 본 평가 프레임웍의 개발은 전문가 의견 수렴을 통한 델파이 방법론으로 접근한 탐색적 연구로서 향후 실증적 후속 연구를 과제로 남기고 있다.

Chemical and Biological Properties of Soils Converted from Paddies and Uplands to Organic Ginseng Farming System in Sangju Region

  • Lim, Jin-Soo;Park, Kee-Choon;Eo, Jinu
    • 한국토양비료학회지
    • /
    • 제47권6호
    • /
    • pp.500-505
    • /
    • 2014
  • In recent years, organic ginseng cultivation has increased because customers prefer organic ginseng products due to the morphological quality as well as the safety such as the residuals of chemically-synthesized pesticides. Therefore, some of paddy and upland fields were converted into organic ginseng fields. Soil chemical properties, soil microflora, and soil-inhabiting animals were investigated in paddy-converted and upland organic ginseng fields in Sangju city, Korea. There was few difference in the soil chemical properties, and the soil nutrient concentrations, such as nitrate-N, Av. $P_2O_5$ between the two field types, and exchangeable cations such as K and Ca were within the ranges which are recommended by the standard ginseng-farming manual. Changes in microflora were also assessed by analyzing phospholipid fatty acid composition. Overall, indicators of microbial groups were greater in the upland field than in the paddy-converted soil, but they were not significantly different. In addition, there was no significant change in the abundance of nematodes, collembolans, and mites between the two field types probably because of the high variation within the field types. In this study, it was suggested that soil chemical and biological properties for organic ginseng cultivation were greatly influenced by the variation of topography and soil management practices rather than field types. Further study may be needed to investigate the influence of these factors on soil chemical and biological properties in organic ginseng soils.

Battery-less Pork Freshness Monitoring Based on High-Efficiency RF Energy Harvesting

  • Nguyen, Nam Hoang;Lam, Minh Binh;Chung, Wan-Young
    • 센서학회지
    • /
    • 제29권5호
    • /
    • pp.293-302
    • /
    • 2020
  • Food safety has emerged as a growing concern for human health in recent times. Consuming contaminated food may lead to serious health problems, and therefore, a system for monitoring food freshness that is both non-detrimental to the quality of food and highly accurate is required to ensure that only high-quality fresh food packages are provided to the customers. This paper proposes a method to monitor and detect food quality using a compact smart sensor tag. The smart tag is composed of three ultra-low-power sensors, which monitor four major indicators of food freshness: temperature, humidity, and the concentrations of ammonia and hydrogen sulfide gases. An RF energy scavenging circuit is integrated into the smart sensor tag to harvest energy from radio waves at a high frequency of 13.56 MHz to supply sufficient power to the tag. Experimental results show that the proposed energy harvester can efficiently obtain energy at a distance of approximately 40 cm from a 4 W reader. In addition, the proposed smart sensor tag can operate without any battery, thereby eliminating the requirement of frequent battery replacement and consequently decreasing the cost. Meanwhile, the freshness of preserved pork is continuously monitored under two conditions--room temperature and refrigerator temperature--both of which are the most common temperatures under which food is generally stored. The food-monitoring experiments are conducted over a period of one week using the proposed battery-less tag. Based on the experimental results, the food assessment is classified into four categories: fresh, normal, low, and spoiled.

국가회계와 지방회계의 구성요소와 제도적 정합성 (The Institutional Elements and Institutional Congruence of National and Local Accounting System)

  • 임동완
    • 한국콘텐츠학회논문지
    • /
    • 제17권10호
    • /
    • pp.343-359
    • /
    • 2017
  • 본 연구는 제도복합성과 제도정합성이라는 신제도주의 이론에 근거하여 정부회계제도를 분석하고 시사점을 제공하고자 하였다. 이러한 분석은 국가회계와 지방회계에 대한 문헌연구와 실제 운영현황에 대한 자료를 기획재정부, 행정안전부, 감사원, 회계통계센터 홈페이지 등에서 체계적으로 수집하여 수행하였다. 분석결과 정부회계제도는 제도복합성 측면에서 다양한 요소로 구성되어 있으며 정보의 생산, 공개, 활용의 측면에서 정합성은 높지 않았다. 이를 향상시키기 위하여 다음과 같은 측면이 개선될 필요가 있었다. 신뢰성 있는 정보의 생산을 위해 회계직 공무원 채용을 신설해야 하고, 감사제도로 발전시킬 필요가 있으며, 국가회계와 지방회계 관련 조직의 협력이 필요하다. 투명한 정보의 공개를 위해 실시간 정보공개 및 국가회계정보와 지방회계정보를 연계하여 공개하는 것이 필요하다. 정보활용을 위해 정보이용자에 대한 교육, 타당한 원가정보와 활용가능한 재정분석지표의 제공, 재정책임관제의 도입, 국가회계와 지방회계가 포함된 통합재무제표의 작성 등이 필요하다.

소형주택의 실내코디네이션 평가요소 분석에 관한 연구 - 한국과 일본의 85㎡이하 소형주택을 중심으로 - (A Study on Evaluation Elements for Interior Coordination of Small-sized Housing - Focused on the below ㎡ small-sized housing between Korea and Japan -)

  • 김소희;서민우;한영호
    • 한국실내디자인학회논문집
    • /
    • 제22권1호
    • /
    • pp.194-202
    • /
    • 2013
  • In the modern society, phenomena such as a decrease in population and an increase in urban small houses caused by demographic changes, a decrease in midium-large housing constructions, and the concentration of one to two person families in the capital area cultivated ground for the growth of small house market. In response to these trends, interior coordination becomes a critical factor to be applied to the small houses in order to suit the residents' needs in most convenient, efficient and aesthetic ways. Therefore, an evaluation element is in demand to extract, evaluate and constantly improve the interior coordination elements. This study extracts and analyzes the essential elements required for small houses into spatial structure, system coordination and interior coordination. In domestic cases, most of spatial structure was conventional and linear while in foreign countries, various variations were found to reflect the needs from different consumers. For the system coordination, convenience played the most important role to emphasize on the easy use of digital system and built-in appliance system in domestic cases. However, in foreign countries, safety issue and economic aspects were the most considered when it comes to the interior coordination. In regard to interior coordination, installations of the storages for the limited small spaces that also support as extended spaces were rare to find in both cases for domestic and international settings. It is expected that systematic studies focused on more objective standards for interior coordination shall be implemented to provide indicators to measure the interior coordination cases in the near future.

Hearing loss screening tool (COBRA score) for newborns in primary care setting

  • Poonual, Watcharapol;Navacharoen, Niramon;Kangsanarak, Jaran;Namwongprom, Sirianong;Saokaew, Surasak
    • Clinical and Experimental Pediatrics
    • /
    • 제60권11호
    • /
    • pp.353-358
    • /
    • 2017
  • Purpose: To develop and evaluate a simple screening tool to assess hearing loss in newborns. A derived score was compared with the standard clinical practice tool. Methods: This cohort study was designed to screen the hearing of newborns using transiently evoked otoacoustic emission and auditory brain stem response, and to determine the risk factors associated with hearing loss of newborns in 3 tertiary hospitals in Northern Thailand. Data were prospectively collected from November 1, 2010 to May 31, 2012. To develop the risk score, clinical-risk indicators were measured by Poisson risk regression. The regression coefficients were transformed into item scores dividing each regression-coefficient with the smallest coefficient in the model, rounding the number to its nearest integer, and adding up to a total score. Results: Five clinical risk factors (Craniofacial anomaly, Ototoxicity, Birth weight, family history [Relative] of congenital sensorineural hearing loss, and Apgar score) were included in our COBRA score. The screening tool detected, by area under the receiver operating characteristic curve, more than 80% of existing hearing loss. The positive-likelihood ratio of hearing loss in patients with scores of 4, 6, and 8 were 25.21 (95% confidence interval [CI], 14.69-43.26), 58.52 (95% CI, 36.26-94.44), and 51.56 (95% CI, 33.74-78.82), respectively. This result was similar to the standard tool (The Joint Committee on Infant Hearing) of 26.72 (95% CI, 20.59-34.66). Conclusion: A simple screening tool of five predictors provides good prediction indices for newborn hearing loss, which may motivate parents to bring children for further appropriate testing and investigations.

Kidney Toxicity Induced by 13 Weeks Exposure to the Fruiting Body of Paecilomyces sinclairii in Rats

  • Jeong, Mi-Hye;Kim, Young-Won;Min, Jeong-Ran;Kwon, Min;Han, Beom-Suk;Kim, Jeong-Gyu;Jeong, Sang-Hee
    • Toxicological Research
    • /
    • 제28권3호
    • /
    • pp.179-185
    • /
    • 2012
  • Paecilomyces sinclairiis (PS) is known as a functional food or human health supplement. However concerns have been raised about its kidney toxicity. This study was performed to investigate the kidney toxicity of PS by 13 week-oral administration to rats. Blood urea nitrogen (BUN), serum creatinine, and kidney damage biomarkers including beta-2-microglobulin (${\beta}2m$), glutathione S-transferase alpha (GST-${\alpha}$), kidney injury molecule 1 (KIM-1), tissue inhibitor of matrix metalloproteinase 1 (TIMP-1), vascular endothelial growth factor (VEGF), calbindin, clusterin, cystatin C, neutrophil gelatinase-associated lipocalin (NGAL) and osteopontin were measured during or after the treatment of PS. BUN, creatinine and kidney damage biomarkers in serum were not changed by PS. However, kidney cell karyomegaly and tubular hypertrophy were observed dose-dependently with higher severity in males. KIM-1, TIMP-1 and osteopontin in kidney and urine were increased dose dependently in male or at the highest dose in female rats. Increased urinary osteopontin by PS was not recovered at 2 weeks of post-exposure in both genders. Cystatin C in kidney was decreased at all treatment groups but inversely increased in urine. The changes in kidney damage biomarkers were more remarkable in male than female rats. These data indicate that the PS may provoke renal cell damage and glomerular filtration dysfunction in rats with histopathological lesions and change of kidney damage biomarkers in kidney or urine. Kidney and urinary KIM-1 and cystatin C were the most marked indicators, while kidney weight, BUN and creatinine and kidney damage biomarkers in serum were not influenced.

Intelligent Hybrid Fusion Algorithm with Vision Patterns for Generation of Precise Digital Road Maps in Self-driving Vehicles

  • Jung, Juho;Park, Manbok;Cho, Kuk;Mun, Cheol;Ahn, Junho
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • 제14권10호
    • /
    • pp.3955-3971
    • /
    • 2020
  • Due to the significant increase in the use of autonomous car technology, it is essential to integrate this technology with high-precision digital map data containing more precise and accurate roadway information, as compared to existing conventional map resources, to ensure the safety of self-driving operations. While existing map technologies may assist vehicles in identifying their locations via Global Positioning System, it is however difficult to update the environmental changes of roadways in these maps. Roadway vision algorithms can be useful for building autonomous vehicles that can avoid accidents and detect real-time location changes. We incorporate a hybrid architectural design that combines unsupervised classification of vision data with supervised joint fusion classification to achieve a better noise-resistant algorithm. We identify, via a deep learning approach, an intelligent hybrid fusion algorithm for fusing multimodal vision feature data for roadway classifications and characterize its improvement in accuracy over unsupervised identifications using image processing and supervised vision classifiers. We analyzed over 93,000 vision frame data collected from a test vehicle in real roadways. The performance indicators of the proposed hybrid fusion algorithm are successfully evaluated for the generation of roadway digital maps for autonomous vehicles, with a recall of 0.94, precision of 0.96, and accuracy of 0.92.

Investigation of Key Factors to measure on-site Performance of a Construction firm

  • Lee, Young-Dai;Kim, Jung-Ki;Acharya, Nirmal Kumar
    • 한국건설관리학회논문집
    • /
    • 제8권6호
    • /
    • pp.246-262
    • /
    • 2007
  • The performance of projects has always been an area of interest in the construction industry. Roles of all construction supply chain partners are necessary; however the role of a contractor firm in the construction project is pivotal. So, this research intended to explore a Construction Firm's performance criteria which could measure the level of performance of that firm in an ongoing project. Data was collected from construction professionals working in three principal project participant organizations, namely Owner, Consultant and Contractor. A total of 113 nos. of performance measuring items were sorted from literature review and used to collect data. Statistical tools processed by SPSS program was employed to analyze the data. Out of total 113 items, only 65 nos. of variables were found to be acceptable to every population group of this study. Factor analysis revealed 12 key performance predicting factors (KPPF) with 53 predictive indicators. 12 KPPFS with index weight are: work progress and smoothening (9.3%), change order management and work accuracy (9.1%), business relationship building (8.1%), adequacy of construction work procedure (8.6%), quality performance (8.0%), health and site safety adequacy (8.8%), Innovative contractor (8.0%), adequacy of construction site information (6.8%), compliance with contract plan/specification requirements (8.9%), creditworthiness and financial capability (8.3%), intra-agency relationship and responsiveness (7.0%) and resource management (9.2%). These results could be useful to project management body to evaluate performance of its contractor firm on site as well as the contractor itself to assess own performance and its subcontractors on-site.

A Study on Using U-Service to Strengthen Urban Competitiveness

  • Shin, Jin-Dong;Lee, Jae-Won;Lee, Sang-Hun;Kim, Hyong-Bok
    • Spatial Information Research
    • /
    • 제17권4호
    • /
    • pp.417-430
    • /
    • 2009
  • 본 연구에서는 유시티의 U-서비스와 도시경쟁력 평가지표의 상호 연관성을 찾고 있다. 연구결과 U-서비스가 빈도에 차이를 보이지만 6개의 도시유형별로 도시경쟁력 강화 수단으로 활용되고 있다. 특히 안전 건강, 활력(경제)도시형에서 적절한 U-서비스 활용은 도시경쟁력 강화에 기여할 수 있는 빈도가 높다. 다음으로 도시경쟁력 평가항목 중 공동항목과 문화도시형에서는 U-서비스가 도시경쟁력 강화에 상대적 기여도가 낮다. 이는 도시의 정책을 평가하는 항목으로 구성되어 있는 공동항목이 도시의 물리적 시설 지능화를 통해 U-서비스를 구현하는 유시티 성격에 부합되지 않는 것이다. 반면 문화도시형과 관련된 U-서비스는 상대적으로 서비스개발이 미약하기 때문이다. 본 연구를 통해 U-서비스는 도시 경쟁력 강화에 활용될 수 있음을 확인할 수 있었다.

  • PDF