• Title/Summary/Keyword: safe use

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Amber Information Design for Supporting Safe-Driving Under Local Road in Small-scale Area (국지지역에서의 안전운전 지원을 위한 경보정보 설계)

  • Moon, Hak-Yong;Ryu, Seung-Ki
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.9 no.5
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    • pp.38-48
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    • 2010
  • Adverse weather (e.g. strong winds, snow and ice) will probably appear as a more serious and frequent threat to road traffic than in clear climate. Another consequence of climate change with a natural disastrous on road traffic is respond to traffic accident more the large and high-rise bridge zone, tunnel zone, inclined plane zone and de-icing zone than any other zone, which in turn calls for continuous adaption of monitoring procedures. Accident mitigating measures against this accident category may consist of intense winter maintenance, the use of road weather information systems for data collection and early warnings, road surveillance and traffic control. While hazard from reduced road friction due to snow and ice may be eliminated by snow removal and de-icing measures, the effect of strong winds on road traffic are not easily avoided. The purpose of the study described here, was to design of amber information the relationship between traffic safety, weather, user information on road weather and driving conditions in local-scale Geographic. The most applications are the optimization of the amber information definition, improvements to road surveillance, road weather monitoring and improved accuracy of user information delivery. Also, statistics on wind gust, surface condition, vehicle category and other relevant parameters for wind induced accidents provide basis for traffic control, early warning policies and driver education for improved road safety at bad weather-exposed locations.

Comparison of Efficacy of Propofol When Used with or without Remifentanil during Conscious Sedation with a Target-Controlled Infuser for Impacted Teeth Extraction

  • Sung, Juhan;Kim, Hyun-Jeong;Choi, Yoon Ji;Lee, Soo Eon;Seo, Kwang-Suk
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.14 no.4
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    • pp.213-219
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    • 2014
  • Background: Clinical use of propofol along with remifentanil for intravenous sedation is increasing in these days, but there are not enough researches to evaluate proper target concentration when these drugs are infused by using target controlled infusion (TCI) pump in dental treatment cases. In this study, we compared efficacy of TCI conscious sedation and target concentration of propofol when it used with or without remifentanil during conscious sedation with the help of a TCI for the surgical extraction of impacted teeth. Methods: After IRB approval, all the charts of patients who had undergone surgical extraction of impacted teeth under propofol TCI sedation for 6 months were selected and reviewed for this study. After reviewal of charts, we could divide patients in two groups. In one group (group 1), only propofol was selected for sedation and initial effect site concentration of propofol was $1{\mu}g/ml$ (n = 33), and in another group (group 2), both propofol and remifentanil was infused and initial effect site concentration of each drug was $0.6{\mu}g/ml$ and 1 ng/ml respectively (n = 25). For each group, average propofol target concentration was measured. In addition, we compared heart rate, respiratory rate, and systolic and diastolic blood pressure as well as oxygen saturation. Besides, BIS, sedation scores (OAAS/S), and subjective satisfaction scores were compared. Results: Between group 1 and 2, there were no significant differences in demographics (age, weight and height), and total sedation time. However, total infused dose and the effect site target concentration of propofol was $163.8{\pm}74.5mg$ and $1.13{\pm}0.21{\mu}g/ml$ in group 1, and $104.3{\pm}46.5mg$ and $0.72{\pm}0.26{\mu}g/ml$ in the group 2 with $1.02{\pm}0.21ng/l$ of the effect site target concentration of remifentanil, respectively. During sedation, there were no differences between overall vital sign, BIS and OAAS/S in 2 groups (P > 0.05). However, we figured out patients in group 2 had decreased pain sensation during sedation. Conclusions: Co-administration of propofol along with remifentanil via a TCI for the surgical extraction of impacted teeth may be safe and effective compared to propofol only administration.

Ecological Management Plan Based on Environmental and Ecological Characteristics for the Tancheon Ecosystem Conservation Area in Seoul (서울시 탄천 생태계 보전지역의 환경생태특성을 고려한 생태적 관리계획)

  • Han Bong-Ho;Kim Jong-Yeop;Hong Suk-Hwan
    • Journal of the Korean Institute of Landscape Architecture
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    • v.32 no.5
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    • pp.84-101
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    • 2004
  • This study presents an ecological management plan for wildbird habitat conservation, an nature-friendly enhancement of bio-diversity using the riverside of the Tancheon Ecosystem Conservation Area in Seoul by analyzing environmental and ecological characteristics. As a result of analyzing actual vegetation, vegetation type was classified into 34 types. Humulus japonicus association covers an area of 441,568.6㎡(31.44%), and Artemisia princeps var. orientalis association covers an area of 89,690.1㎡(6.39%). Sandy plain as valuable wildbird habitat covers an area of 89,965.9㎡(6.4%). 125 taxa including 34 families, 93 genera, 107 species, and 18 varieties were recorded and the number of naturalized plants were 41 taxa at the survey site. Total naturalized index(NI) and urbanized index(UI) were recorded as 32.8%, and 15.5%. As a result of analyzing the herb plants association structure by surveying 8 belt-transects, the humid native plants was dominant in the partially adjacent revetment edge and damp riverside. On the other hand, naturalized plants was so extensively dominant that it was necessary to establish an ecological management plan. The observed wildbirds belonged to 50 species, 6,118 individuals, and 7 restricted species by law, which were Accipiter gentilis, Falco tinnunculus, Buteo hemilasius, and Buteo buteo. Oriolus chinensis,Hirundo rustica, and Alcedo atthis. The ecological administration plan for Tancheon Ecosystem Conservation Area as follows: in ecological land-use planning, the conservation area(695,518.5㎡) has native woody and herb vegetation and sandy plain with water as an wildbird habitat. The restoration area(653,702.7㎡) has a naturalized plants distribution are with artificial revetment. The nature-friendly Riverside Area(55,414.9㎡) was an easily approached area with damaged riverside vegetation, and a safe area to wildbird habitat. In riverside restoration planning, the artificial riverside should be restored to its natural riverside vegetation, and the artificial embankment should be restored with edge shrubs for wildbird habitat or revegetated for natural riverside landscape. For naturalized plants management planning, we selected naturalized plant species to be weeded out, and suggested an application method for ecological management.

Safety Evaluation of 30 kGy Irradiated Chocolate Ice Cream (30 kGy 감마선 조사된 초코아이스크림의 안전성 평가)

  • Jeon, Young Eun;Yin, Xing Fu;Chung, Cha-Kwon;Kang, Il-Jun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.6
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    • pp.898-903
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    • 2013
  • This study was investigated the potential toxicity of gamma-irradiated chocolate ice cream for its future use in space. Chocolate ice cream was irradiated at a dose of 30 kGy at a temperature of $-20^{\circ}C$. For the animal study, AIN-93G was used as a control diet and irradiated and non-irradiated chocolate ice cream diets were administered to male and female ICR mice (ten mice per group) for three months. During the experimental period, the group fed irradiated chocolate ice cream did not show any changes in appearance, behavior, mortality, body weight, organ weight, or food consumption compared to the control. Also, all biochemical parameters, including hematology profiles, erythrocyte counts, and serum biochemical values were in normal ranges. In histopathological examinations of liver and kidney tissues, there were no significant differences between the control group and the group fed irradiated chocolate ice cream. These results indicate that chocolate ice cream irradiated at 30 kGy did not cause any toxic effects and could be applied for the development of safe and hygienic space food.

Teratoma Formation in Immunocompetent Mice After Syngeneic and Allogeneic Implantation of Germline Capable Mouse Embryonic Stem Cells

  • Aldahmash, Abdullah;Atteya, Muhammad;Elsafadi, Mona;Al-Nbaheen, May;Al-Mubarak, Husain Adel;Vishnubalaji, Radhakrishnan;Al-Roalle, Ali;Al-Harbi, Suzan;Manikandan, Muthurangan;Matthaei, Klaus Ingo;Mahmood, Amer
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5705-5711
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    • 2013
  • Background: Embryonic stem cells (ESCs) have the potential to form teratomas when implanted into immunodeficient mice, but data in immunocompetent mice are limited. We therefore investigated teratoma formation after implantation of three different mouse ESC (mESC) lines into immunocompetent mice. Materials and Methods: BALB/c mice were injected with three highly germline competent mESCs (129Sv, BALB/c and C57BL/6) subcutaneously or under the kidney capsule. After 4 weeks, mice were euthanized and examined histologically for teratoma development. The incidence, size and composition of teratomas were compared using Pearson Chi-square, t-test for dependent variables, one-way analysis of variance and the nonparametric Kruskal-Wallis analysis of variance and median test. Results: Teratomas developed from all three cell lines. The incidence of formation was significantly higher under the kidney capsule compared to subcutaneous site and occurred in both allogeneic and syngeneic mice. Overall, the size of teratoma was largest with the 129Sv cell line and under the kidney capsule. Diverse embryonic stem cell-derived tissues, belonging to the three embryonic germ layers, were encountered, reflecting the pluripotency of embryonic stem cells. Most commonly represented tissues were nervous tissue, keratinizing stratified squamous epithelium (ectoderm), smooth muscle, striated muscle, cartilage, bone (mesoderm), and glandular tissue in the form of gut- and respiratory-like epithelia (endoderm). Conclusions: ESCs can form teratomas in immunocompetent mice and, therefore, removal of undifferentiated ESC is a pre-requisite for a safe use of ESC in cell-based therapies. In addition the genetic relationship of the origin of the cell lines to the ability to transplant plays a major role.

Acute Normovolemic Hemodilution Effects on Perioperative Coagulation in Elderly Patients Undergoing Hepatic Carcinectomy

  • Guo, Jian-Rong;Jin, Xiao-Ju;Yu, Jun;Xu, Feng;Zhang, Yi-Wei;Shen, Hua-Chun;Shao, Yi
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4529-4532
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    • 2013
  • Background: Acute normovolemic hemodilution (ANH) has been widely used to prevent the massive blood loss during hepatic carcinoma. The influences of ANH on coagulation function are still controversy, especially in elderly patients. The study observed ANH effects on coagulation function and fibrinolysis in elderly patients undergoing the disease. Materials and Methods: Thirty elderly patients (aged 60-70 yr) with liver cancer (ASA I or II) taken hepatic carcinectomy from February 2007 to February 2008 were randomly divided into ANH group (n=15) and control group (n=15). After tracheal intubation, patients in ANH group and control group were infused with 6% hydroxyethyl starch (130/0.4) and Ringer's solution, respectively. Blood samples were drawn from patients in both groups at five different time points: before anesthesia induction (T1), 30 min after ANH (T2), 1 h after start of operation (T3), immediately after operation (T4), and 24 h after operation (T5). Then coagulation function, soluble fibrin monomer complex (SFMC), prothrombin fragment (F1+2), and platelet membrane glycoprotein (CD62P and activated GP IIb/GP IIIa) were measured. Results: The perioperative blood loss and allogeneic blood transfusion were recorded during the surgery. The perioperative blood loss was not significantly different between two groups (p>0.05), but the volume of allogeneic blood transfusion in ANH group was significantly less than in control group ($350.0{\pm}70.7$) mL vs. ($457.0{\pm}181.3$) mL (p<0.01). Compared with the data of T1, the prothrombin time (PT) and activated partial thromboplastin time (APTT) measured after T3 were significantly longer (p<0.05) in both groups, but within normal range. There were no significant changes of thrombin time (TT) and D-dimer between two groups at different time points (p>0.05). SFMC and F1+2 increased in both groups, but were not statistically significant. PAC-1-positive cells and CD62P expressions in patients of ANH group were significantly lower than those at T1 (p<0.05) and T2-T5 (p>0.05). Conclusions: ANH has no obvious impact on fibrinolysis and coagulation function in elderly patients undergoing resection of liver cancer. The study suggested that ANH is safe to use in elderly patients and it could reduce allogeneic blood transfusion.

The Study of Korean Yellow Dyeing (한국(韓國) 황염(黃染) 연구(硏究))

  • Lee, Yang-Sup
    • Journal of the Korean Society of Costume
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    • v.4
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    • pp.13-24
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    • 1981
  • The color yellow was considered from ancient time to the Chosun Dynasty as the central color. Thus, this color became the royal color for the costumes in the palace. It is generally known to usthat the color yellow was controled in use both for the general public and in the royal palaces. However, in the later part of Chosun Dynasty, the color yellow was used not only for the king's costumes but also used for women's tops and for the linings of clothing. Especially, in some of the costumes that belonged to the later period of the Chosun Dynasty, we can still see lots of bright yellow tops. Also there are many green dyed official robes and various costumes for women. It is a true fact that people could not derive the color green from the plants as they did with yellow. The only way they could make the color green was to mix indigo and yellow together. By repeating the difficult process of making various dyes constantly during many centuries, the Korean people developed the marvelous technique of making natural color. Those plants used to make the color yellow are ; Gardenia, Phellodendron amurense, Turmeric, Coptis, Safflower, Arthraxon hispidus, Styphnolobium japonicum. While synthetic dye causes pollution, natural coloring by plants is as safe and useful as the color itself is lovely. Yet it is tragic to know that this traditional culture of making beautiful natural colors was cut off. There is no way to know today the traditionally correct method to derive colors from the plants. Therefore, it is our aim and challenge to find out the original way to dye and develop it and preserve it as our non-polluted folk art. In regard to natural dyeing, we must say that is very difficult to prepare and preserve natural dyes. In the first place, people had to get the right plants at an appropriate time. Then they could not keep those plants too long. Finally, much depended upon the mordant as well as various conditions and dyeing procedures. All those things influenced greatly the quality of color, some times producing a very pretty color and other times a very dull one. It is very appropriate that the natural dye art should be recognized and appreciated anew by Korea since it provides satisfaction to historical and folk artistic demands as well as to those of fashion conscious modern society for high quality consumption items. We propose two stages of development. The first stage is to explore native dye plants and encourage their cultivation. The second stage is to extract from the plants desirable dye which will enhance national culture.

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Standard Manual Development for Infants and Children's Urban Railway Accident Prevention (도시철도 안전사고 예방을 위한 유아·어린이 대상 표준 매뉴얼 개발)

  • Kang, Soo-Hee;Kwon, Young-Jong;Kim, Yeon Kyu;Go, Seung-ryul
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.3
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    • pp.587-594
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    • 2016
  • Even though accidents occurred inside urban railway stations demage not only one person, but also surrounding people, it can be prevented by cautious actions. This research aims at infants and children, which can maximize the educational impacts, to develop a safety textbook which can educate safety rules and behavioral know-how to reduce the accidents occurred in urban railway stations, and at parents and teachers to gather opinions through surveys on the research's future direction. This research conducts a case study and comparison analysis on domestic and foreign safety manuals, which is organized in a book form of fairy tales educating safety rules for readers to utilize the urban railway by steps from boarding to taking off. Through a survey we conducted for parents and teachers as providing the safety textbook developed through this research, we could get the positive evaluations and gather opinions on the future research direction. The safety textbook developed in a form of fairy tale book through this research is for infants and children to use the urban railway in a safe manner, which is expected to evoke the interests and curiosity and create the educational impacts on users.

Thermal analysis of LNG storage tank for LNG bunkering system (LNG 벙커링용 고효율 LNG 저장탱크 열해석)

  • Yun, Sang-kook
    • Journal of Advanced Marine Engineering and Technology
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    • v.39 no.9
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    • pp.876-880
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    • 2015
  • In 2016, the IMO's new rules for an 80% reduction in NOx emissions in newly built ships will necessitate the use of LNG as a clean fuel. So far, the developed European countries have led the development of LNG bunkering ships and related facilities. An LNG bunkering system stores LNG in a horizontal or vertical IMO "C"-Type tank insulated with perlite powder, and a vacuum in the annular space between the double walls, like the cryogenic liquid nitrogen tank. Current storage tanks have high heat leakage, evaporating over 2.0% daily, and are difficult to build with the required vacuum. A more efficiently insulated storage tank could reduce the evaporation rate. This research carried out thermal analysis on a new effective insulation method that separates high vacuum in the annular space between two tanks with a solid insulation material, such as urethane foam, lining the outer vessel. This highly efficient insulation system obtained an evaporation rate of 0.03% per day under a $10^{-3}torr$ vacuum, and an evaporation rate of 0.11% at $10^{-45}torr$. Even if the space loses its vacuum, the new insulation system showed a lower evaporation rate of 4.12% than the present perlite system of 4.9%. This newly developed tank can increase the efficiency of LNG storage tank and may help keep LNG bunkering systems safe.

The Effects of Evodia Rutaecarpa and Ephedra Sinica on the Resting Metabolic Rate and Body Composition of Obese Women on a Low-Calorie Diet: A Double-blinded Randomized Controlled Clinical Trial (오수유와 마황이 저열량식이요법을 병행한 비만여성환자의 체구성성분 및 휴식대사량에 미치는 영향)

  • Park Jung-Mi;Kim Ho-Jun;Kim Jin-Ah;Kim Su-Jin;Ko Byeong-Pyo
    • The Journal of Korean Medicine
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    • v.26 no.3 s.63
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    • pp.249-262
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    • 2005
  • Backgrounds : As obesity prevails as an epidemic. diet programs including low-calorie diets are developed continuously. It is generally believed that a low-calorie diet is commonly followed by resting metabolic rate decrease and ultimate weight regain. Ephedra and Evodia are known to have sympathomimetic and anti-obesity effect. Objectives : This study was a prospective, double-blinded, randomized md placebo-controlled clinical trial to evaluate the effects of Ephedra sinica and Evodia rutaecarpa on resting metabolic rate (RMR), weight, body composition, and short-term safety in obese women on low-calorie diet. Methods : 125 otherwise healthy obese women (body mass Index ${\geq}\;25kg/m^2$) were recruited and randomly assigned to three groups: Ephedra group (n=41), Evodia group (n =45), and placebo group (n=39). Subjects were administered Ephedra extract in capsules (pseudo-ephedrine 31.52mg) or Evodia extract in capsules (evodiamine 6.75mg, rutaecarpine 0.66mg) or placebo capsules as well as participating in a low-calorie diet for 8 weeks, Resting metabolic rate and body composition were measured at baseline,4 and 8 weeks. Basic serum exams were performed to evaluate the short-term safety of the herbs and changes of lipid variables. Results : All three groups showed significant BMI decreases probably due to low-calorie diet. Among them, the Ephedra group manifested most prominent BMI-reducing effect and towered total cholesterol and triglycerides significantly. The RMR was not changed during the 8-week diet in all groups. No significant difference among the groups was found in RMR, either. Stbject with higher RMR than the mean at the baseline showed a tendency to keep their RMR more stable during the diet program. Conclusions : Ephedra with a low-calorie diet was effective in reducing BMI. RMR change was not compensated by herbal medicines. RMR change seemed to be affected rather by constitution and body composition than medicine. Ephedra and Evodia were proven to be safe for sort-term use in herbal form. Especially, Ephedra was effective in lowering total cholesterol and triglycerides during the 8 weeks.

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