• Title/Summary/Keyword: risk-assessment

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A Cancer Risk Assessment of Di (2- ethylhexyl ) -phthalate - Application of MOE (Margin of Exposure) Approach (Di(2-ethylhexyl)phthalate의 발암위해성평가 - MOE(Margin of Exposure) 방법론의 활용 -)

  • 최시내;이효민;윤은경;서경원;김효정;박종세
    • Toxicological Research
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    • v.18 no.1
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    • pp.99-106
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    • 2002
  • The United States Environmental Protection Agency (EPA) characterized the cancer hazard of di(2-ethylhexyl)-phthalate (DEHP) as a B2 group (probable human carcinogen) and proposed "Guide-lines for Carcinogen Risk Assessment". This guidelines proposed alternative methods for analyzing carcinogen dose-response data and for extrapolating the effects of observed at high dose to predict that might occur at lower doses relevant to human exposure. This proposed guidelines state that "If in a particular case, the evidence indicated a threshold, as in the case of carcinogenicity being secondary to another toxicity that has a threshold, the margin of exposure analysis for toxicity is the same as is done for a non-cancer endpoint". DEHP is excellent candidate for reconideration under the new guidelines for carcinogen risk assessment (John Doull et al., 1998). This study is conducted about risk assessment for infant exposure on DEHP in powdered milk wing methodology in EPA's new guideline on carcinogenic risk assessment. Estimated cancer risk of DEHP in powdered milk and cow milk is 2.83$\times$$10^5$ (using cancer potency: 1.4$\times$$10^2$/ (mg/kg/day)) as mean and MOE is 12075 (using selected NOEL 20 mg/kg/day) as mean. mg/kg/day) as mean.

A risk assessment of $CO_2$ geological storage for domestic application (이산화탄소 지중저장의 국내적용을 위한 위해성 평가 방안)

  • Lee, Kang-Ryel;Lee, Dae-Soo
    • 한국신재생에너지학회:학술대회논문집
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    • 2011.05a
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    • pp.220.1-220.1
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    • 2011
  • In recent years, the importance of Carbon Capture and Storage (hereafter CCS) is growing bigger and bigger. The development and commercialization of CCS technology are concerned for reducing carbon dioxide($CO_2$) emissions. For the most studies, the technology of $CO_2$ storage is known as the geological storage, ocean sequestration, mineral carbonation, industrial utilization, and so on. The geological storage is adjudged the most reasonable technology from economic and environmental aspects. Generally, the $CO_2$ geological storage is comprised of compression - transportation - drilling/injection - storage/management process. The critical problem is a leakage of $CO_2$ in all process. For resolving a leakage problem, it is necessary to predict and build a monitoring system. Those systems are proved safety of a leakage and received positive social perceptions of $CO_2$ geological storage. For those reasons, a risk assessment of $CO_2$ geological storage is required. A risk assessment is an estimated process of the possible effects when spilling $CO_2$. Although numerous studies of risk assessment have studied, it is incomplete to evaluate a risk and disaster quantitatively. The risk assessment will be developed for domestic application and safe $CO_2$ geological storage considering characteristics of Korea.

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Probabilistic Risk Assessment for Construction Projects (건설공사의 확률적 위험도분석평가)

  • 조효남;임종권;김광섭
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1997.10a
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    • pp.24-31
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    • 1997
  • Recently, in Korea, demand for establishment of systematic risk assessment techniques for construction projects has increased, especially after the large construction failures occurred during construction such as New Haengju Bridge construction projects, subway construction projects, gas explosion accidents etc. Most of existing risk analysis modeling techniques such as Event Tree Analysis and Fault Tree Analysis may not be available for realistic risk assessment of construction projects because it is very complex and difficult to estimate occurrence frequency and failure probability precisely due to a lack of data related to the various risks inherent in construction projects like natural disasters, financial and economic risks, political risks, environmental risks as well as design and construction-related risks. Therefor the main objective of this paper is to suggest systematic probabilistic risk assessment model and demonstrate an approach for probabilistic risk assessment using advanced Event Tree Analysis introducing Fuzzy set theory concepts. It may be stated that the Fuzzy Event Tree AnaIysis may be very usefu1 for the systematic and rational risk assessment for real constructions problems because the approach is able to effectively deal with all the related construction risks in terms of the linguistic variables that incorporate systematically expert's experiences and subjective judgement.

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Development of safety system for Road Tunnel - The study of Quantitative risk assessment for middle scale road tunnel with natural ventilation system - (도로터널 방재시스템 개발 - 자연환기를 수행하는 중규모 도로터널의 정량적 위험도평가관한 연구 -)

  • Yoo, Ji-Oh;Shin, Hyun-Jun;Kim, Jong-Won
    • Proceedings of the SAREK Conference
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    • 2008.11a
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    • pp.67-70
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    • 2008
  • As a part of the project on road tunnel fire safety system development, Quantitative Risk Assessment program was developed. In this study, We carried out Quantitative Risk Assessment with this program by using a factor of cross passage interval, warning announcement time and congestion ratio etc for 1km tunnel with natural ventilation. In the case of 250m below of cross passage interval, Risk value due to warning announcement time was a slightly changed. but if cross passage interval is more than 250m, expected fatalities in the same HRR(heat release rate) was sharp increased. As a result, Quantitative Risk Assessment program which was developed in this research project is possible to risk assessment with ventilation type, cross passage for evacuation and detection system response property etc. hereafter, this program look forward to use as a tool for road tunnel performance based design.

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Fault Tree Analysis for Risk Assessment of CO2 Leakage from Geologic Storage (지중 저장 이산화탄소의 누출 위험도 평가를 위한 결함수 분석)

  • Lee, Sang Il;Lee, Sang Ki;Hwang, Jin Hwan
    • Journal of Environmental Impact Assessment
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    • v.18 no.6
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    • pp.359-366
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    • 2009
  • CCS (Carbon Capture and Storage) is considered as the most promising interim solution to deal with the greenhouse gas such as $CO_2$ responsible for global warming. Even though carefully chosen geologic formations are known to contain stored gas for a long time period, there are potential risks of leakage. Up to now, applicable risk assessment procedures for the leakage of $CO_2$ are not available. This study presents a basis for risk analysis applicable to a complex geologic storage system. It starts with the classification of potential leakage pathways. Receptors and the leakage effect on them are identified and quantified. Then, a fault tree is constructed, which yields the minimum cut set (i.e., the most vulnerable leakage pathway) and quantifies the probability of the leakage risk through the cut set. The methodology will provide a tool for risk assessment in a CCS project. The outcomes of the assessment will not only ensure the safety of the CCS system but also offer a reliable and efficient monitoring plan.

Prior Research and Case Study on Overseas Assessment Models for Developing Risk Assessment Model on Domestic Customer Products (국내 소비자 제품의 위해성 평가 모델 개발을 위한 해외 평가 모델 선행조사 및 사례 비교)

  • Han, Shinho;Lee, Jongmin;Kim, Heongkee;Seo, Kum-hee
    • Journal of Applied Reliability
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    • v.15 no.3
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    • pp.207-215
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    • 2015
  • Safety' can be used in a variety of ways and may also have different meanings when used in theoretical field and routinely used. In this paper, the 'safety' means that human injury, fire or physical accident condition does not occur while used by the end-user. The meaning of safety may be different by era and culture. Even in contemporary era, the meaning can be used differently by country, region and culture. As the rights of consumers are increasingly reinforced, we can expect the acceptable risk or safety level can rise higher. In this paper, the R-map of Japan and the European risk assessment guidelines (RAPEX) were reviewed considering domestic incidents database status and its applicability. Because it is difficult to make a model based on a R-map, a revised model was developed mainly based on European Assessment Model with a combination of the important characteristics of Japan model R-map. Also utilizing this revised model, the availability as a new risk assessment model was confirmed by comparing the test results for the same scenarios to the other risk assessment model (RAPEX/RAG).

Environmental Risk Assessment for Ivermectin, Praziquantel, Tamiflu and Triclosan (Ivermectin, praziquantel, tamiflu, triclosan의 환경위해성평가)

  • Ryu, Taekwon;Kim, Jungkon;Kim, Kyungtae;Lee, Jaewoo;Kim, Jieun;Cho, Jaegu;Yoon, Junheon;Lee, Jaean;Kim, Pilje;Ryu, Jisung
    • Journal of Environmental Health Sciences
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    • v.44 no.2
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    • pp.196-203
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    • 2018
  • Objectives: The purpose of this study was to assess environmental risk on the emerging contaminants of concern, such as ivermetin, parziquantel, tamiflu and triclosan. Furthermore, we tried to provide a more efficient management practice and a basis for future studies of risk assessment on those substances. Methods: Predicted no effect concentration (PNEC) and predicted environmental concentration (PEC) were determined through modeling and literature reviews. Environmental risk assessment was evaluated by calculating HQ (hazard quotient) by a comparison of PEC (or measured environmental concentration (MEC)) and PNEC. Results: HQ value of tamiflu calculated from MEC was 1.9E-03. For ivermectin and triclosan, the HQ values were not available because these were not detected in the aquatic environment. The toxicity of ivermectin and triclosan showed a very low value, indicating a high level of HQ. However, praziquantel can be categorized into the material that do not require management since they have less than HQ 1. Conclusion: Based on the results of the initial risk assessment, it is assumed that the ivermectin and triclosan have potential to cause direct adverse effects on the aquatic environment. To conduct an accurate environmental risk assessment, the further study on PEC estimation of such contaminants should be actively carried out.

A Basic Study on Assessment Criterion of the Risk Factor for the Marine Traffic Environment (해상교통환경 위험요소 평가기준 설정을 위한 기초 연구)

  • Kim, Chol-Seong;Lee, Hong-Hoon
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.18 no.5
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    • pp.431-438
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    • 2012
  • The representative risk evaluation techniques of the marine traffic environment are the FSA, PAWSA, & IWRAP. For the development of these techniques, the risk factors suitable to the marine traffic environment should be selected & the assessment criterion of the risk factors should be provided. The risk factors were selected as the factors that relate both to the frequency of casualty & to the consequence of casualty because the risk was defined as the frequency of casualty times the consequence of that casualty on the existing techniques. But, the risk factors relate to the consequence of casualty are excluded because the risk is defined as the sum of the risk factors including the frequency and the consequence by factors on this study. The 20 kinds of risk factors to compose the risk are selected and classified into 5 categories according to similar nature through the analysis of preceding study on the classification of the risk factors. Finally, as the foundation of risk assessment model's development for domestic marine traffic environment, the practical assessment criterion of the risk factors are suggested.

A Case Study on the Estimation of the Risk based on Statistics (산업재해통계기반 Risk 산정에 관한 연구)

  • Woo, Jong-Gwon;Lee, Mi-Jeong;Seol, Mun-Su;Baek, Jong-Bae
    • Journal of the Korean Society of Safety
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    • v.36 no.4
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    • pp.80-87
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    • 2021
  • Risk assessment techniques are processes used to evaluate hazardous risk factors in construction sites, facilities, raw materials, machinery, and equipment, and to estimate the size of risk that could lead to injury or disease, and establish countermeasures. The most important thing in assessing risk is calculating the size of the risk. If the size of the risk cannot be calculated objectively and quantitatively, all members who participated in the evaluation would passively engage in establishing and implementing appropriate measures. Therefore, this study focused on predicting accidents that are expected to occur in the future based on past occupational accident statistics, and quantifying the size of the risk in an overview. The technique employed in this study differs from other risk assessment techniques in that the subjective elements of evaluators were excluded as much as possible by utilizing past occupational accident statistics. This study aims to calculate the size of the risk, regardless of evaluators, such as a manager, supervisor, safety manager, or employee. The size of the risk is the combination of the likelihood and severity of an accident. In this study, the likelihood of an accident was evaluated using the theory of Bud Accident Chainability, and the severity of an accident was calculated using the occupational accident statistics over the past five years according to the accident classification by the International Labor Organization.

Risk Assessment of Drinking Water Pollutants (다중이용시설에서의 먹는물 위해성 평가)

  • Back, Young Maan;Chung, Yong;Park, Je Chul;Kim, Hyung Jin
    • Journal of Korean Society on Water Environment
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    • v.22 no.6
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    • pp.1107-1108
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    • 2006
  • As expanding municipal and industrial areas since started the economic development plan in earnest in 1970's, the water resource, mainly river surface water has been seriously polluted. Nevertheless, being upgraded in their treatment technologies for the drinking water, the safety has been issued one of crucially social problem in Korea. The water authorities has tried to improve the quality such as amending the drinking water quality standard to be monitored; hazardous chemicals and microorganis have been added and now 55 items, before 47 items, since in 2002. The Water Authorities of Seoul, the capital city of Korea, planned to assess the safty of drinking water quality after amended the standard. This study was conducted to assess the risk due to polluted chemicals including 21 heavy metals, VOCs, pesticides, PAHs, DBPs and organic chemicals among the regulated items. The risk assessment were undertaken hazard identification, exposure assessment, dose-response assessment and risk characterization. For the exposoure assessment, tap water, bottled water and purified water were sampled and analyzed in February, 2004. Risk characterization of detected chemicals was categorized into carcinogenecity and noncarcinogenecity, and estimated the excess of carcinogens and compapared with the reference dose (RfD) of noncarcinogenns. The excess risk of carcinogens from samples were considered comparatively in the acceptable levels; $10^{-6}$ for cancer risk and hazard quotient (HQ) 1.0 for noncancer risk. The deteced levels were estimated in $10^{-5}{\sim}10^{-6}$ of cancer risk and below 1.0 of HQ of noncancer risk. While three kinds of water were determined within the acceptal levels, DBPs were detected in tap water and purified were and some undesireable chemicals such as more fluoride detected rather than the quality stanadard. For the drinking water safety, it shoud be continuously monitored, assessed and managed as well risk communiction between the authoritis and public.