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Environmental Risk Assessment for Ivermectin, Praziquantel, Tamiflu and Triclosan

Ivermectin, praziquantel, tamiflu, triclosan의 환경위해성평가

  • Ryu, Taekwon (Accident Prevention and Assessment Division, National Institute of Chemical Safety) ;
  • Kim, Jungkon (Accident Prevention and Assessment Division, National Institute of Chemical Safety) ;
  • Kim, Kyungtae (National Institute of Environmental Research) ;
  • Lee, Jaewoo (National Institute of Environmental Research) ;
  • Kim, Jieun (National Institute of Environmental Research) ;
  • Cho, Jaegu (National Institute of Environmental Research) ;
  • Yoon, Junheon (Accident Prevention and Assessment Division, National Institute of Chemical Safety) ;
  • Lee, Jaean (National Institute of Environmental Research) ;
  • Kim, Pilje (National Institute of Environmental Research) ;
  • Ryu, Jisung (Accident Prevention and Assessment Division, National Institute of Chemical Safety)
  • 류태권 (화학물질안전원 사고예방심사과) ;
  • 김정곤 (화학물질안전원 사고예방심사과) ;
  • 김경태 (국립환경과학원 위해성평가연구과) ;
  • 이재우 (국립환경과학원 위해성평가연구과) ;
  • 김지은 (국립환경과학원 위해성평가연구과) ;
  • 조재구 (국립환경과학원 위해성평가연구과) ;
  • 윤준헌 (화학물질안전원 사고예방심사과) ;
  • 이재안 (국립환경과학원 위해성평가연구과) ;
  • 김필제 (국립환경과학원 위해성평가연구과) ;
  • 류지성 (화학물질안전원 사고예방심사과)
  • Received : 2018.04.01
  • Accepted : 2018.04.20
  • Published : 2018.04.28

Abstract

Objectives: The purpose of this study was to assess environmental risk on the emerging contaminants of concern, such as ivermetin, parziquantel, tamiflu and triclosan. Furthermore, we tried to provide a more efficient management practice and a basis for future studies of risk assessment on those substances. Methods: Predicted no effect concentration (PNEC) and predicted environmental concentration (PEC) were determined through modeling and literature reviews. Environmental risk assessment was evaluated by calculating HQ (hazard quotient) by a comparison of PEC (or measured environmental concentration (MEC)) and PNEC. Results: HQ value of tamiflu calculated from MEC was 1.9E-03. For ivermectin and triclosan, the HQ values were not available because these were not detected in the aquatic environment. The toxicity of ivermectin and triclosan showed a very low value, indicating a high level of HQ. However, praziquantel can be categorized into the material that do not require management since they have less than HQ 1. Conclusion: Based on the results of the initial risk assessment, it is assumed that the ivermectin and triclosan have potential to cause direct adverse effects on the aquatic environment. To conduct an accurate environmental risk assessment, the further study on PEC estimation of such contaminants should be actively carried out.

Keywords

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