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http://dx.doi.org/10.5668/JEHS.2018.44.2.196

Environmental Risk Assessment for Ivermectin, Praziquantel, Tamiflu and Triclosan  

Ryu, Taekwon (Accident Prevention and Assessment Division, National Institute of Chemical Safety)
Kim, Jungkon (Accident Prevention and Assessment Division, National Institute of Chemical Safety)
Kim, Kyungtae (National Institute of Environmental Research)
Lee, Jaewoo (National Institute of Environmental Research)
Kim, Jieun (National Institute of Environmental Research)
Cho, Jaegu (National Institute of Environmental Research)
Yoon, Junheon (Accident Prevention and Assessment Division, National Institute of Chemical Safety)
Lee, Jaean (National Institute of Environmental Research)
Kim, Pilje (National Institute of Environmental Research)
Ryu, Jisung (Accident Prevention and Assessment Division, National Institute of Chemical Safety)
Publication Information
Journal of Environmental Health Sciences / v.44, no.2, 2018 , pp. 196-203 More about this Journal
Abstract
Objectives: The purpose of this study was to assess environmental risk on the emerging contaminants of concern, such as ivermetin, parziquantel, tamiflu and triclosan. Furthermore, we tried to provide a more efficient management practice and a basis for future studies of risk assessment on those substances. Methods: Predicted no effect concentration (PNEC) and predicted environmental concentration (PEC) were determined through modeling and literature reviews. Environmental risk assessment was evaluated by calculating HQ (hazard quotient) by a comparison of PEC (or measured environmental concentration (MEC)) and PNEC. Results: HQ value of tamiflu calculated from MEC was 1.9E-03. For ivermectin and triclosan, the HQ values were not available because these were not detected in the aquatic environment. The toxicity of ivermectin and triclosan showed a very low value, indicating a high level of HQ. However, praziquantel can be categorized into the material that do not require management since they have less than HQ 1. Conclusion: Based on the results of the initial risk assessment, it is assumed that the ivermectin and triclosan have potential to cause direct adverse effects on the aquatic environment. To conduct an accurate environmental risk assessment, the further study on PEC estimation of such contaminants should be actively carried out.
Keywords
Environmental risk assessment; contaminants of emerging concerns; pharmaceuticals; personal care products;
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