• Annals of Clinical Neurophysiology
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• v.21 no.1
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• pp.30-35
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• 2019

Background: Postural tachycardia syndrome (POTS) refers to the presence of orthostatic intolerance symptoms associated with a heart rate increment of greater than 30 beats/min, usually up to 120 beats/min, on head-up tilt test. Symptoms related to POTS are usually light-headedness, palpitations and tremor, but syncope can also occur. The pathophysiology of POTS is heterogeneous and its prognosis is uncertain. Methods: We prospectively evaluated patients who met the criteria for POTS, at baseline and follow-up, using composite autonomic symptom scores and autonomic tests to assess the autonomic function. We compared the clinical and autonomic test results between baseline and follow-up. Results: Sixty-eight patients met the inclusion criteria for POTS and forty-five patients were ultimately followed up for at least 1 year after baseline. The patients were predominantly young females (84%), with a mean age of 21 years. Most patients showed improved orthostatic symptoms and more than a quarter of patients had no longer met the criteria for POTS at follow-up. Conclusions: Most patients had a benign outcome in that they could resume their daily activities without great limitations. Our results demonstrated a relatively favorable prognosis in most patients with POTS.

• Electronics and Telecommunications Trends
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• v.37 no.2
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• pp.30-41
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• 2022

As the society is superaging, the number of patients with movement disabilities due to musculoskeletal or nervous system illness is rapidly increasing. To improve public health and reduce medical expenses, it is essential to develop rehabilitation systems that allow patients to resume their daily-life activities. However, the existing musculoskeletal illness diagnosis and rehabilitation method is limited in terms of precision and efficiency because it is based on an empirical diagnosis and prescription without regard for individual characteristics. To overcome these limits, it is critical to design a novel concept of routine rehabilitation therapy device that is capable of inducing musculoskeletal balance by the precise analysis of musculoskeletal usage patterns via the motion and the muscle activity tracking of linked muscles. This study introduces the trend of on-skin sensor device technology for routine musculoskeletal monitoring and therapy. For on-skin rehabilitation systems, skin-adhesive and stretchable motion/posture, electromyography, pressure sensors, small-size and low-power wireless sensor interfaces, and user-friendly rehabilitation contents based on new algorithms are combined.

• ETRI Journal
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• v.45 no.1
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• pp.75-92
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• 2023

Level 3 autonomous vehicles require conditional autonomous driving in which autonomous and manual driving are alternately performed; whether the driver can resume manual driving within a limited time should be examined. This study investigates whether the demographics and subjective driving tendencies of drivers affect the take-over performance. We measured and analyzed the reengagement and stabilization time after a take-over request from the autonomous driving system to manual driving using a vehicle simulator that supports the driver's take-over mechanism. We discovered that the driver's reengagement and stabilization time correlated with the speeding and wild driving tendency as well as driving workload questionnaires. To verify the efficiency of subjective questionnaire information, we tested whether the driver with slow or fast reengagement and stabilization time can be detected based on machine learning techniques and obtained results. We expect to apply these results to training programs for autonomous vehicles' users and personalized human-vehicle interfaces for future autonomous vehicles.

• Journal of the Korean Society of Safety
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• v.38 no.1
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• pp.87-92
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• 2023

The number of unmanned light rail train operators is continuously increasing in Korea. In a failure event during an operation due to the nature of the unmanned operation, recovery is performed based on the remote control. However, if remote recovery is not feasible, safety personnel arrive at the train to resume the train operation. There are regulations on safety personnel and the suspension time of the train operation. However, there is currently no rule for safety personnel deployment. Currently, railway operating organizations operate in three scenarios: safety personnel on board trains, stationed at stations, and deployed at major stations. Four major factors influence the downtime for each emergency response scenario. However, these four influencing factors vary too much to predict results with simple calculations. In this study, four influencing factors were considered as random variables with high uncertainty. In addition, the Monte Carlo method was applied to each scenario for the safety personnel deployment to predict train service downtime. This study found a 17% difference in train service suspension by safety personnel deployment scenario. The results of this study can be used in setting service goals, such as standards for future safety personnel placement and frequency of service interruptions.

• Journal of Korea Society of Digital Industry and Information Management
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• v.20 no.3
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• pp.1-12
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• 2024

This study explores how generative AI technology can be utilized to create more efficient and effective employment portfolios in the rapidly changing job market and recruitment landscape. To achieve this, the study first conducted an in-depth analysis of recent employment trends and recruitment patterns, categorizing various generative AI tools based on their application in areas such as resume writing, portfolio design, and video production. Particularly, this research includes a case study of a career planning course in a university setting, where generative AI was applied, to empirically evaluate its potential for educational use. Through this case study, the research thoroughly examines how generative AI can contribute to efficient job preparation and skill enhancement for job seekers. The findings suggest that generative AI plays a critical role in providing personalized information, generating creative ideas, and enhancing both the visual and functional quality of employment portfolios, ultimately contributing to increased competitiveness in the job market. The study also emphasizes the need for further research on the expanding scope and effectiveness of generative AI as the technology continues to evolve.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• v.25 no.3
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• pp.316-321
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• 2023

Developmental venous anomalies (DVAs) are composed of mature venous vessels that lack malformed or neoplastic elements. Although the hemorrhage risk is considered negligible, some patients may have neurological symptoms attributable to acute infarction or intracranial hemorrhage secondary to thrombosis, in the absence of a coexisting cavernous malformation. We report the case of a 42-year-old patient who presented with acute left-hand paresis secondary to a subcortical hemorrhage. This bleeding originated from a DVA in the corticospinal tract area and was surgically drained through an awake craniotomy. To accomplish this, we used a trans-precentral sulcus approach. After the complete removal of the coagulum, small venous channels appeared, which were coagulated. No associated cavernoma was found. Although the main DVA trunk was left patent, no signs of ischemia or venous infarction were observed after coagulating the small venous channels found inside the hematoma cavity. Two weeks after the procedure, the patient's hand function improved, and he was able to resume desktop work. DVA-associated hemorrhage within the cortico-spinal tract could be safely removed with modern awake mapping techniques. This technique allowed the patient to rapidly improve his hand function.

• Journal of the Korean Society of Systems Engineering
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• v.15 no.2
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• pp.66-71
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• 2019

In digital pathology, an electronic system in the biomedical domain storage of the files is a big constrain and because all the analysis and annotation takes place at every user-end manually, it becomes even harder to manage the data that is being shared inside an enterprise. Therefore, we need such a storage system which is not only big enough to store all the data but also manage it and making communication of that data much easier without losing its true from. A virtual server setup is one of those techniques which can solve this issue. We set a main server which is the main storage for all the virtual machines(that are being used at user-end) and that main server is controlled through a hypervisor so that if we want to make changes in storage overall or the main server in itself, it could be reached remotely from anywhere by just using the server's IP address. The server in our case includes XML-RPC based API which are transmitted between computers using HTTP protocol. JAVA API connects to HTTP/HTTPS protocol through JAVA Runtime Environment and exists on top of other SDK web services for the productivity boost of the running application. To manage the server easily, we use Tkinter library to develop the GUI and pmw magawidgets library which is also utilized through Tkinter. For managing, monitoring and performing operations on virtual machines, we use Python binding to XML-RPC based API. After all these settings, we approach to make the system user friendly by making GUI of the main server. Using that GUI, user can perform administrative functions like restart, suspend or resume a virtual machine. They can also logon to the slave host of the pool in case of emergency and if needed, they can also filter virtual machine by the host. Network monitoring can be performed on multiple virtual machines at same time in order to detect any loss of network connectivity.

• Journal of the Korea Convergence Society
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• v.11 no.4
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• pp.277-285
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• 2020

To advance the competitiveness of dental hygienist students, the concept of 'employment competitiveness index' was introduced. By utilizing the index, the preparedness of employment and awareness of employment was studied, to enhance the understandings of students' career and preparations for employment. Both hypothesis 1-basic contents of a student's resume or so-called "specifications" and employment competitiveness index have positive correlation-and hypothesis 2-the 'inspirational factors' and employment competitiveness index have positive correlation-were accepted. Among the 'basic factors', attractiveness and foreign language scored the least while understanding of employers, certificates, and job experiences scored the least among the inspirational factors category. Using this study, various organizations such as universities will be able to provide better guidelines regarding employment or career. In conclusion, this study aims to provide advanced, effective and competitive guidelines for dental hygienist curriculum planning, developing non-curriculum courses, special lectures, and providing advice regarding employment.

• Reproductive and Developmental Biology
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• v.31 no.2
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• pp.115-120
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• 2007

This study was conducted to examine the effect of several saccharides on the induction of capacitation and acrosome reaction (AR) and to examine the effects of mono and polysaccharides on the penetration activity of boar spermatozoa. Spermatozoa were inseminated in medium with fucose, galactose and mannose as monosaccharide, and fucoicIan. galactan and marman as polysaccharide. The penetration rates were significantly (p<0.05) lower in medium with galactose (40.6%), mannose (38.1%), fucose (41.6%) and fucoidan (36.6%) compared with control (56.7%). The rates of AR were increased (40.7 to 59.8%) by the preincubation periods prolonged from 0 to 4 hr (p<0.05). Similar tendencies were observed in AR when spermatozoa were treated with monosaccharides, but not significantly differ among the groups treated with different time of preincubation with some exception of galactose. When spermatozoa were treated with polysaccharides, the rates of AR were significantly (p<0.05) increased by preincubation time prolonged from 0 to 4 hr with an exception of fucoidan. In conclusion, the present study suggests that penetration rate of spermatozoa is higher in presence of polysaccharides than monosaccharides. Also, it may resume that the comparing to control, the all saccharides (L-fucose, D-galactose, D-mannose, fucoidan. galactan and mannan)-treated groups slightly increase the AR pattern as preincubation time prolonged.

• Molecules and Cells
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• v.43 no.10
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• pp.848-855
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• 2020

Cells assemble stress granules (SGs) to protect their RNAs from exposure to harmful chemical reactions induced by environmental stress. These SGs release RNAs, which resume translation once the stress is relieved. During stem cell differentiation, gene expression is altered to allow cells to adopt various functional and morphological features necessary to differentiate. This process induces stress within a cell, and cells that cannot overcome this stress die. Here, we investigated the role of SGs in the progression of stem cell differentiation. SGs aggregated during the neuronal differentiation of human bone marrow-mesenchymal stem cells, and not in cell lines that could not undergo differentiation. SGs were observed between one and three hours post-induction; RNA translation was restrained at the same time. Immediately after disassembly of SGs, the expression of the neuronal marker neurofilament-M (NF-M) gradually increased. Assembled SGs that persisted in cells were exposed to salubrinal, which inhibited the dephosphorylation of eukaryotic translation initiation factor 2 subunit 1 (eIF2α), and in eIF2α/S51D mutant cells. When eIF2α/S51A mutant cells differentiated, SGs were not assembled. In all experiments, the disruption of SGs was accompanied by delayed NF-M expression and the number of neuronally differentiated cells was decreased. Decreased differentiation was accompanied by decreased cell viability, indicating the necessity of SGs for preventing cell death during neuronal differentiation. Collectively, these results demonstrate the essential role of SGs during the neuronal differentiation of stem cells.