• Journal of Biomedical Engineering Research
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• v.28 no.5
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• pp.676-683
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• 2007

A non-invasive respiratory gated radiotherapy system like those based on external anatomic motion gives better comfortableness to patients than invasive system on treatment. However, higher correlation between the external and internal anatomic motion is required to increase the effectiveness of non-invasive respiratory gated radiotherapy. Both of invasive and non-invasive methods need to track the internal anatomy with the higher precision and rapid response. Especially, the non-invasive method has more difficulty to track the target position successively because of using only image processing. So we developed the system to track the motion for a non-invasive respiratory gated system to accurately find the dynamic position of internal structures such as the diaphragm and tumor. The respiratory organ motion tracking apparatus consists of an image capture board, a fluoroscopy system and a processing computer. After the image board grabs the motion of internal anatomy through the fluoroscopy system, the computer acquires the organ motion tracking data by image processing without any additional physical markers. The patients breathe freely without any forced breath control and coaching, when this experiment was performed. The developed pattern-recognition software could extract the target motion signal in real-time from the acquired fluoroscopic images. The range of mean deviations between the real and acquired target positions was measured for some sample structures in an anatomical model phantom. The mean and max deviation between the real and acquired positions were less than 1mm and 2mm respectively with the standardized movement using a moving stage and an anatomical model phantom. Under the real human body, the mean and maximum distance of the peak to trough was measured 23.5mm and 55.1mm respectively for 13 patients' diaphragm motion. The acquired respiration profile showed that human expiration period was longer than the inspiration period. The above results could be applied to respiratory-gated radiotherapy.

• Investigative Magnetic Resonance Imaging
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• v.22 no.1
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• pp.71-77
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• 2018

Purpose: To develop a two-dimensional (2D) image-based respiratory motion correction technique for free-breathing coronary magnetic resonance angiography (MRA). Materials and Methods: The proposed respiratory navigator obtained aliased a 2D sagittal image from under-sampled k-space data and utilized motion correlation between the aliased images. The proposed navigator was incorporated into the conventional coronary MRA sequence including the diaphragm navigator and tested in three healthy subjects. Results: The delineation of major coronary arteries was significantly improved using the proposed 2D motion correction (S/I and A/P) compared to one-dimensional (S/I) correction using the conventional diaphragm navigator. Conclusion: The 2D image-based respiratory navigator was proposed for free-breathing coronary angiography and showed the potential for improving respiratory motion correction compared to the conventional 1D correction.

• Journal of the Korean Society of Physical Medicine
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• v.16 no.3
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• pp.29-36
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• 2021

PURPOSE: The respiratory function and range of joint mobility deteriorate due to aging, respectively, and the respiratory function may be related to the range of joint mobility. To the best of the authors' knowledge, there has been little research on how the deterioration of the range of joint mobility caused by aging is related directly to the respiratory function. This study investigated the relationship between the respiratory function and the range of joint motion in the cervical and lumbar regions of older adults. METHODS: Thirty-two older adults participated in the study. The forced vital capacity (peak expiratory flow: PEF and forced expiratory volume in 1 second: FEV1) and the range of cervical joint motion were assessed in all subjects. The results were analyzed using the Pearson's correlation coefficient. RESULTS: The respiratory function moderately correlated with age. A moderate correlation was observed between FEV1 and right cervical lateral flexion. PEF was moderately correlated with the lumbar lateral flexion. In addition, FEV1 correlated strongly with lumbar lateral flexion. CONCLUSION: The respiratory function was correlated with the cervical and lumbar lateral flexion. Therefore, rehabilitation of the respiratory function should involve improving the limited range of motion of the joints, and a stretching program is needed for older adults.

• Physical Therapy Rehabilitation Science
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• v.10 no.3
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• pp.328-336
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• 2021

Objective: The purpose of this study was to investigate the effect of cervical range of motion training on the change in respiratory function growth rate at the group and individual level in stroke patients and stroke patients with tracheostomy tube. Design: A Multilevel Growth Model Methods: 8 general stroke patients and 6 stroke patients who had a tracheostomy tube inserted were subjected to cervical range of motion training 3 times a week for 4 weeks. Force vital capacity (FVC), Forced expiratory volume in the first second (FEV1), Forced expiration ratio (FEV1/FVC) and Manual assist peak cough flow (MPCF) were measured. Data were analyzed using descriptive statistics and multilevel analysis with HLM 8.0. Results: A significant difference was found in the respiratory function analysis growth rate of the entire group (p<0.05), and two groups were added to the research model. The linear growth rate of respiratory function in patients with general stroke increased with the exception of FEV1/FVC (p<0.05). Stroke patients with tracheostomy tube showed a decreasing pattern except for FVC. In particular, MPCF showed a significantly decreased result (p<0.05). Conclusions: This study found that the maintenance of improved respiratory function in stroke patients with tracheostomy tube decreased over time. However, cervical range of motion training is still a useful method for respiratory function in general stroke patients and stroke patients with tracheostomy tube.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.7
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• pp.2191-2208
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• 2022

Motion blur in PET (Positron emission tomography) images induced by respiratory motion will reduce the quality of imaging. Although exiting methods have positive performance for respiratory motion correction in medical practice, there are still many aspects that can be improved. In this paper, an improved 3D unsupervised framework, Res-Voxel based on U-Net network was proposed for the motion correction. The Res-Voxel with multiple residual structure may improve the ability of predicting deformation field, and use a smaller convolution kernel to reduce the parameters of the model and decrease the amount of computation required. The proposed is tested on the simulated PET imaging data and the clinical data. Experimental results demonstrate that the proposed achieved Dice indices 93.81%, 81.75% and 75.10% on the simulated geometric phantom data, voxel phantom data and the clinical data respectively. It is demonstrated that the proposed method can improve the registration and correction performance of PET image.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.12
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• pp.111-122
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• 2014

As radiotherapy has become one of the widely used techniques in cancer treatment, accurate tracking of patient's respiratory motion is considered to be more important in treatment planning and dose calculations. Inaccurate motion tracking can cause severe issues such as errors in target/normal tissue delineation and increasing the volume of healthy tissues exposed to high doses. Different methods have been introduced to estimate the respiratory motion, but most of them require some electronic devices or expensive materials. As an inexpensive and easy to use alternative to the previous methods, we propose a new 3D respiratory motion tracking method by using stereo vision techniques of detecting and decoding visual coded markers.

• Proceedings of the IEEK Conference
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• 2003.07e
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• pp.1863-1866
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• 2003

In this study, respiratory motion is modeled by a 2-Dimensional linear expanding-shrinking movement. According to the introduced model, respiratory motion imposes phase error, non-uniform sampling and amplitude modulation distortions on the acquired MRI data. When the motion parameters are known or can be estimated, a reconstruction algorithm based on superposition method was used to removed the MRI artifact. For the purpose of estimating unknown motion parameters, we applied the spectrum shift method to find the respiratory fluctuation function, the x directional expansion coefficient and its center, and also we used the minimum energy method to find the y directional expansion coefficient and its center. The effectiveness of this presented method is shown by Computer simulations.

• Proceedings of the Korea Institute of Convergence Signal Processing
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• 2003.06a
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• pp.58-61
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• 2003

In this study, a planar respiratory motion is modeled by a 2-D linear expanding-shrinking movement. According to the introduced model, respiratory motion imposes phase error, non-uniform sampling and amplitude modulation distortions on the acquired MRI data. When the motion parameters are known or can be estimated, a construction algorithm based on superposition method was used to remove the MRI artifact. For the purpose of estimating unknown motion parameters, we used the spectrum shift method to find the respiratory fluctuation function, the x directional expansion coefficient and its center, and we also used the minimum energy method to find the y directional expansion coefficient and its center. Finally the effectiveness of this presented method is shown by computer simulations.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2005.04a
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• pp.59-63
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• 2005

Respiration motion causes movement of internal structures in the thorax and abdomen, making accurate delivery of radiation therapy to tumors in those areas a challenge. Accounting for such motion during treatment, therefore, has the potential to reduce margins drawn around the clinical target volume (CTV), resulting in a lower dose to normal tissues (e.g., lung and liver) and thus a lower risk of treatment induced complications. Among the techniques that explicitly account for intrafraction motion are breath-hold, respiration gating, and 4D or tumor-tracking techniques. Respiration gating methods periodically turn the beam on when the patient's respiration signal is in a certain part of the respiratory cycle (generally end-inhale or end-exhale). These techniques require acquisition of some form of respiration motion signal (infrared reflective markers, spirometry, strain gauge, thermistor, video tracking of chest outlines and fluoroscopic tracking of implanted markers are some of the techniques employed to date), which is assumed to be correlated with internal anatomy motion. In preliminary study for the respiratory gating radiation therapy, we performed to measurement of this respiration motion signal. In order to measure the respiratory motion signals of patient, respiration measurement system (RMS) was composed with three sensor (spirometer, thermistor, and belt transducer), 4 channel data acquisition system and mobile computer. For two patients, we performed to evaluation of respiratory cycle and shape with RMS. We observed under this system that respiratory cycle is generally periodic but asymmetric, with the majority of time spent. As expected, RMS traced patient's respiration each other well and be easily handled for application.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2006.08a
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• pp.61-61
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• 2006