• Title/Summary/Keyword: resistance factor

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Effects of Constitutional Food on Nurse's NK Cell Activity and Stress Reduction (체질푸드가 간호사의 스트레스 감소와 NK세포 활성도에 미치는 영향)

  • Park, Sun-Mi
    • The Journal of the Korea Contents Association
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    • v.19 no.3
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    • pp.500-509
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    • 2019
  • The study looked at the effect of body food on stress reduction and NK cell activity in improving natural healing for nurses, and examined whether it is effective in preventing and curing human health. The study was conducted for 30 days on 22 nurses who currently worked for more than a year at a general hospital in Gyeonggi Province. Stress measurements were conducted through pulse wave measuring instrument, and blood tests were conducted on the activity of NK cells. Treatment of collected data was performed by Paired t-testing through the Stat program SPSS 21 and providing body food suitable for the physical quality of participants after the classification of the body based on the internal diameter of the emperor and scholarship. Studies have shown that the effect on reducing the stress of body food has significant positive effects and that body food is effective for the activity of NK cells. This study has the following significance: First, the main health threat factor for modern people is the increased resistance of natural healing through body food to stress, which has the potential to prevent disease. Second, immunodeficiency in disease prevention and treatment is very important, which can increase the natural healing power of the human body by increasing the activity of NK cells through body food.

Molecular Detection of Virulence Factors in Carbapenem-Resistant Pseudomonas aeruginosa Isolated from a Tertiary Hospital in Daejeon (대전지역의 3차 병원에서 분리된 Carbapenem 내성 Pseudomonas aeruginosa의 병독성 인자 검출)

  • Cho, Hye Hyun
    • Korean Journal of Clinical Laboratory Science
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    • v.51 no.3
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    • pp.301-308
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    • 2019
  • The emergence and spread of multidrug resistant (MDR) Pseudomonas aeruginosa is a critical problem worldwide. The pathogenesis of P. aeruginosa is due partly to the production of several cell-associated and extracellular virulence factors. This study examined the distribution of virulence factors and antimicrobial resistance patterns of carbapenem-resistant P. aeruginosa (CRPA) isolated from a tertiary hospital in Daejeon, Korea. Antimicrobial susceptibility testing was performed using the disk diffusion method, and PCR and DNA sequencing were performed to determine for the presence of virulence genes. In addition, the sequence type (ST) of MDR P. aeruginosa was investigated by multilocus sequence typing (MLST). Among 32 CRPA isolates, 14 (43.8%) were MDR and the major ST was ST235 (10 isolates, 71.4%). All isolates were positive for the presence of virulence genes and the most prevalent virulence genes were toxA, plcN, and phzM (100%). All isolates carried at least eight or more different virulence genes and nine (28.1%) isolates had 15 virulence genes. The presence of the exoU gene was detected in 71.4% of the MDR P. aeruginosa isolates. These results indicate that the presence of the exoU gene can be a predictive marker for the persistence of MDR P. aeruginosa isolates.

Immunostimulatory Activity of Agarwood through Activation of MAPK Signaling Pathway in RAW 264.7 Murine Macrophages (RAW 264.7 대식세포에서 MAPKs 신호 전달 경로의 활성화를 통한 침향의 면역 자극 활성)

  • Ji, Seon Yeong;Hwangbo, Hyun;Lee, Hyesook;Koo, Young Tae;Kim, Jin Soo;Lee, Ki Won;Noh, Dong Jin;Choi, Yung Hyun
    • Journal of Life Science
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    • v.31 no.8
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    • pp.745-754
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    • 2021
  • Deterioration of the immune function weakens the body's resistance to various infections, leading to a series of diseases. Immunomodulatory biomaterials have been used to reduce the side effects of immunosuppressants or to enhance immunity. Agarwood is the aromatic resinous portion of Aquilaria trees that has been traditionally used as a medicinal herb for the treatment of various diseases. Although previous studies have shown that agarwood can improve the body's immunity, evidence for this claim is still lacking. In this study, the immune-enhancing effects of the agarwood methanol extracts of Aquilaria malaccensis Lamk were evaluated in a RAW 264.7 macrophage model. Based on the results, the agarwood extracts markedly enhanced phagocytosis in the absence of cytotoxicity. The agarwood extract-treated RAW 264.7 cells exhibited the typical morphology of activated macrophages, which are spindle-shaped with elongated filopodia. Agarwood extract also significantly increased the production of nitric oxide (NO), which is associated with the increased expression of inducible NO synthase. Moreover, the secretion and expression levels of cytokines, such as tumor necrosis factor-α and interleukin (IL)-1β and IL-6, were increased by agarwood treatment. Notably, these are also associated with a mitogen-activated protein kinase signaling pathway. Taken together, our findings provide scientific evidence that agarwood has potential immune-enhancing effects in vitro.

A Study on the Effect of Pile Surface Roughness on Adfreeze Bond Strength (말뚝표면 거칠기에 따른 동착강도 변화에 관한 연구)

  • Choi, Changho
    • Journal of the Korean GEO-environmental Society
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    • v.12 no.12
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    • pp.79-88
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    • 2011
  • Adfreeze bond strength develops upon freezing of pore water within soil and at foundation surface. It has been reported that various factors like temperature, soil type, and pile surface roughness affect adfreeze bond strength. Especially, pile surface roughness has been considered as a primary factor to design pile foundation in frozen ground. It has usually been estimated with fixed correction factors for pile materials. However, even if the pile foundation material is the same, the surface roughness could vary depending on the production circumstances. In this study, laboratory test was carried out to quantitatively analyze the effects of surface roughness on the adfreeze bond strength, and fractal dimension was used as a measure for surface roughness. Test results showed that adfreeze bond strength increased with decreasing temperature, increasing vertical stress and surface roughness. The adfreeze bond strength varies sensitively with surface roughness in the early freezing section of $-2^{\circ}C$, but its sensitivity decreased in the temperature ranging between $-2^{\circ}C$ to $-5^{\circ}C$. The results conclude that the roughness highly affects the frictional resistance of pile surface in frozen ground; however, the roughness does not affect considerably when the temperature drops below about $-2^{\circ}C$.

The Effect of Crystallization by Heat Treatment on Electromagnetic Interference Shielding Efficiency of Carbon Fibers (열처리 온도에 의한 구조 결정성이 탄소섬유의 전자파 차폐 성능에 미치는 영향)

  • Kim, Jong Gu;Chung, Choul Ho;Lee, Young-Seak
    • Applied Chemistry for Engineering
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    • v.22 no.2
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    • pp.138-143
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    • 2011
  • To investigate the electromagnetic interference shielding efficiency (EMI SE) property based on heat treatment effects of carbon fibers in various temperatures, the polyacrilonitrle-based carbon fibers were prepared by electrospinning method and treated at 1073, 1323, 1873 and 2573 K. The surface morphology of carbon fibers was investigated by using FE-SEM and the carbon crystallization was studied by Raman spectroscopy based on effects of reaction temperatures. The electrical conductivity was obtained by measuring the surface resistance with four probe method on carbon crystallization. The permittivity, permeability and EMI SE were investigated by using S-parameter in the range of 800~4500 MHz. In case of carbon fibers treated at 2573 K, the improved carbon crystallization was confirmed by Raman spectrum and the enhanced electrical conductivity showing 54.7 S/cm was also observed. The permittivity was dramatically improved by factor of 4 based on effect of high reaction temperature. Eventually, the highly improved EMI SE value was obtained showing around 41.7 dB.

Electromagnetic Interference Shielding Behaviors of Electroless Nickel-loaded Carbon Fibers-reinforced Epoxy Matrix Composites (무전해 니켈도금된 탄소섬유강화 에폭시기지 복합재료의 전자파 차폐특성)

  • Hong, Myung-Sun;Bae, Kyong-Min;Lee, Hae-Seong;Park, Soo-Jin;An, Kay-Hyeok;Kang, Shin-Jae;Kim, Byung-Joo
    • Applied Chemistry for Engineering
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    • v.22 no.6
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    • pp.672-678
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    • 2011
  • In this work, carbon fibers were electrolessly Ni-plated in order to investigate the effect of metal plating on the electromagnetic shielding effectiveness (EMI-SE) of Ni-coated carbon fibers-reinforced epoxy matrix composites. The surfaces of carbon fibers were characterized by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). Electric resistance of the composites was tested using a 4-point-probe electric resistivity tester. The EMI-SE of the composites was evaluated by means of the reflection and adsorption methods. From the results, it was found that the EMI-SE of the composites enhanced with increasing Ni plating time and content. In high frequency region, the EMI-SE didn't show further increasing with high Ni content (Ni-CF 10 min) compared to the Ni-CF 5 min sample. In conclusion, Ni content on the carbon fibers can be a key factor to determine the EMI-SE of the composites, but there can be an optimized metal content at a specific electromagnetic frequency region in this system.

Trademark Protection In The Fashion Industry with ICT Issues (패션산업의 상표권 보호 및 ICT 쟁점 - Louboutin 사건, Levi 사건에 대한 분석을 중심으로 -)

  • Lee, Jae-Kyoung
    • Journal of Legislation Research
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    • no.44
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    • pp.185-209
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    • 2013
  • With the broader range of information and communications technology, of which fashion is a foundational medium, to analyze fashion as an information technology in order to better understand the industry's desire for intellectual property protection, popular resistance to such protection, and the most efficacious balance between them in terms of creative expression. It is, therefore to be focused on cultural and historical reasons for the limited degree of intellectual property protection extended in the past to certain categories of human creativity, including fashion design. So, the question of why some tension still exists between creators and consumers of fashion, how information theory can contribute to an explanation for that tension, and what role law can play in its resolution with Louboutin case and Levi case. Consumers and designers alike are better served by promotion of fair competition, lower litigation costs, and the inventive synergy of the fashion industry. Louboutin shows the comfortable, respectful limits of trademark law, while Levi illustrates the dangerous, overreaching deference that a few circuits have granted to famous marks. The Supreme Court could clarify the standard for dilution claims, requiring that a junior mark be "identical or nearly identical" or even "significantly similar" to a senior mark. Courts should need a deference in making dilution determinations and can choose to make this factor quite subjective with the highest degree of similarity.

Development of Permit Vehicle Classification System for Bridge Evaluation in Korea (허가차량 통행에 대한 교량의 안전성 평가를 위한 허가차량 분류 체계 개발)

  • Yu, Sang Seon;Kim, Kyunghyun;Paik, Inyeol;Kim, Ji Hyeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.12
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    • pp.845-856
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    • 2020
  • This study proposes a bridge evaluation system for indivisible permit vehicles such as hydraulic cranes. The permit loads for the bridge evaluation are divided into three categories: routine permit loads, special permit 1 loads, and special permit 2 loads. Routine permit and special permit 1 vehicles are allowed to cross a bridge with normal traffic. For these two permits, the standard lane model in the Korean Highway Bridge Design Code was adopted to consider normal traffic in the same lane. Special permit 2 vehicles are assumed to cross a bridge without other traffic. Structural analyses of two prestressed-beam bridges and two steel box girder bridges were conducted for the proposed permit loads. The rating factors of the four bridges for all permit loads were calculated as sufficiently large values for the moment and shear force so that crossing the bridges can be permitted. A reliability assessment of the bridges was performed to identify the reliability levels for the permit vehicles. It was confirmed that the reliability level of the minimum required strength obtained by the load-resistance factors yields the target reliability index of the design code for the permit vehicles.

Conservativeness of Response Displacement Method used in Seismic Response Analysis of Power Cable Tunnels (전력구의 지진응답해석법에 사용되는 응답변위법의 보수성 평가)

  • Lim, Jae-Sung;Yang, Dae-Seung;Hwang, Kyeong-Min;Kim, Jae-Min
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.34 no.4
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    • pp.243-254
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    • 2021
  • In this study, the conservatism of the response displacement method (RDM) for the seismic response analysis of box-shaped power cable tunnels was evaluated. A total of 50 examples were used considering the cross-sections of 25 power cable tunnels and two soil conditions for each power cable tunnel. The following three methods were applied for the analysis by the RDM: (1) single cosine method, (2) double cosine method, and (3) dynamic free-field analysis method. A refined dynamic analysis method considering soil-structure interaction (SSI) was employed to compare the conservatism of the RDM. The double cosine method demonstrated the most conservative result, while the dynamic free-field analysis method yielded the least deviation. The soil stiffness reduction factor, C, for the double cosine method was recommended to be 0.9 and 0.7 for the operational performance and collapse prevention levels, respectively, to ensure a probability of at least 80% that the member force by the RDM is larger than that of dynamic SSI analysis.

A Study on the Emulsifying Stability of W/O Type Sunscreen Cream by the Hansen Solubility Parameter (Hansen Solubility Parameter 를 통한 W/O 형 자외선차단 제형의 유화 안정성에 관한 연구)

  • Kim, Dong Hee;Lee, Jin Jae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.47 no.4
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    • pp.273-280
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    • 2021
  • The water resistance is important factor for sunscreen formulations. Generally a sunscreen cream was formulated by a water-in-oil (W/O) emulsion. In the W/O emulsion system, silicone oils are added to improve the texture of formulations. Silicone oils have low compatibility with organic sunscreen agent, causing problems with the stability in emulsion. In this study, the compatibility between various oils in the W/O emulsion was derived numerically using Hansen solubility parameter (HSP) at first. HSP is represented a dispersion degree, a polarity, and a hydrgen bond in a composition. In this study, various emulsions were prepared according to the types of oils with different HSP values and then monitored by a viscosity and morphology according to the time and temperature. The HSP values of components and the experimental results have similar activities for the stability of emulsions. HSP made it easy to select oil with high compatibility. When the compatibility of the oil phase in the W/O emulsion was high, the viscosity change over time was small. The stability was improved under the freeze-thaw cycle (-15 ℃ ~ 45 ℃). In the future, if the composition of the ingredients is optimized through HSP, it is expected that it will be helpful in the development of W/O type sunscreen formulations that are excellent in use and stability.