• 한국인터넷방송통신학회논문지
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• 제17권1호
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• pp.83-88
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• 2017

본 논문은 디지털 부호를 전송할 때 통신 채널에서 발생되는 부호간 간섭을 줄일 수 있는 MMA (Multiple Modulus Algorithm) 적응 등화 알고리즘에 adaptive modulus와 adaptive step size 개념을 적용한 H-MMA (Hybrid-MMA) 알고리즘의 등화 성능평가에 관한 것이다. 기존의 MMA 적응 등화기의 탭 계수 갱신은 등화기 출력를 이용하여 오차 신호를 얻게 되므로 2차원 QAM 신호에서 진폭과 위상을 보상할 수 있지만, 이때 스텝 크기와 modulus는 고정되므로 등화 성능이 저하된다. 이와 같은 문제점을 개선하기 위하여 등화기 출력 신호의 크기에 비례토록 adaptive modulus와 적응 스텝 크기를 변화시킬 수 있는 Hybrid adaptive 개념을 MMA에 적용하므로서 2차원 QAM 신호에서 등화 성능을 개선할 수 있다. 논문에서 제안하는 H-MMA 알고리즘의 성능을 기존의 MMA 알고리즘과 비교하기 위하여 동일한 채널에서 컴퓨터 시뮬레이션을 수행하였다. 시뮬레이션 결과 수렴 속도에서는 제안 H-MMA가 MMA보다 다소 느려지지만, 정상 상태 이후 모든 성능 지수에서 훨씬 우월하며 등화 잡음이 감소됨을 확인하였다.

• 대한화장품학회지
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• 제25권4호
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• pp.123-131
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• 1999

Liquid crystal known as a rheological barrier to coalescence of oil droplets, increases emulsion stability, water-holding capacity and promotes active material penetration to skin. Some investigation for its rheological characteristics have been reported but its relations to consumer perception have been rarely published. In this study, oil/water emulsion and oil/liquid crystal/water systems were manufactured using the same composition or Behenyltrimethylammonium chloride/Cetostearyl alcohol/Lanolin oil. and rheological properties or each system were investigated with Cone and Plate rheometer. The formation of liquid crystalline phase was observed with polarized microscope and Differential Scanning Calorimeter. Continuous shear experiment, creep, yield and water holding capacity were measured for oil/water and oil/liquid crystal/water systems. The results were compared with sensory evaluations. Oil/liquid crystal/water system showed higher,viscosity at the same shear rate. higher viscoelasticity and higher yield stress than oil/water system. These properties were expected to show good spreadability and excellent richness without waxiness in hair can: products of creme type. This expectation was consistent with the results of sensory experiments. Water-holding capacity was evaluated by measuring residual water of specimens at specific temperature and relative humidity. Oil/liquid crystal/water system was proved to have higher ability to hold water in comparison with oil/water system. The results indicated that oil/liquid crystal/water system was of benefit to rheological properties creme type hair care products.

• Nuclear Engineering and Technology
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• 제38권2호
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• pp.147-154
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• 2006

Thermal fatigue of the coolant circuits of PWR plants is a major issue for nuclear safety. The problem is especially accute in mixing zones, like T-junctions, where large differences in water temperature between the two inlets and high levels of turbulence can lead to large temperature fluctuations at the wall. Until recently, studies on the matter had been tackled at EDF using steady methods: the fluid flow was solved with a CFD code using an averaged turbulence model, which led to the knowledge of the mean temperature and temperature variance at each point of the wall. But, being based on averaged quantities, this method could not reproduce the unsteady and 3D effects of the problem, like phase lag in temperature oscillations between two points, which can generate important stresses. Benefiting from advances in computer power and turbulence modelling, a new methodology is now applied, that allows to take these effects into account. The CFD tool Code_Saturne, developped at EDF, is used to solve the fluid flow using an unsteady L.E.S. approach. It is coupled with the thermal code Syrthes, which propagates the temperature fluctuations into the wall thickness. The instantaneous temperature field inside the wall can then be extracted and used for structure mechanics computations (mainly with EDF thermomechanics tool Code_Aster). The purpose of this paper is to present the application of this methodology to the simulation of a straight T-junction mock-up, similar to the Residual Heat Remover (RHR) junction found in N4 type PWR nuclear plants, and designed to study thermal striping and cracks propagation. The results are generally in good agreement with the measurements; yet, in certain areas of the flow, progress is still needed in L.E.S. modelling and in the treatment of instantaneous heat transfer at the wall.

• 한국지반공학회논문집
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• 제19권4호
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• pp.83-93
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• 2003

본 연구에서는 낙동강 하류 을숙도에 분포하는 0.558%의 세립분을 함유한 자연 사질토 지반에 대하여 느슨, 중간, 그리고 조밀한 지반 상태를 재현하여 초기정적전단응력의 영향을 정적 및 동적 시험을 통해 응력경로와 과잉간극수압 소산 및 잔류변형 거동을 규명하고, Bolton 이론에 의거한 파괴시 최대 유효마찰각을 상대밀도에 의한 영향과 구속압의 영향을 고려하여 제시하였다. 파괴선과 상전이점의 거리는 초기전단응력이 증가할수록 가까워지고, 느슨한 모래의 경우 그 영향이 커서 조밀한 모래의 응력경로로 접근하는 경향을 보인다. 압밀응력비 조건이 1.4에서 1.8로 변함에 따라, 상대밀도의 증가와 함께 보다 큰 액상화 저항강도를 보이고 조밀한 상대밀도 조건에서는 유사한 CSR값을 보였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1996년도 하계학술대회 논문집 C
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• pp.2004-2006
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• 1996

A thermally driven polysilicon micro actuator has been fabricated using surface micromachining techniques. It consists of P-doped polysilicon as a structural layer and TEOS (tetracthylorthosilicate) as a sacrificial layer. The polysilicon was annealed for the relaxation of residual stress which is the main cause to its deformation such as bending and buckling. And the newly developed HF VPE (vapor phase etching) process was also used as an effective release method for the elimination of sacrificial TEOS layer. The thickneas of polysilicon is $2{\mu}m$ and the lengths of active and passive polysilicon cantilevers are $500{\mu}m$ and $260{\mu}m$, respectively. The actuation is incurred by die thermal expansion due to the current flow in the active polysilicon cantilever, which motion is amplified by lever mechanism. The moving distance of polysilicon micro actuator was experimentally conformed as large as $21{\mu}m$ at the input voltage level of 10V and 50Hz square wave. The actuating characteristics are investigated by simulating the phenomena of heat transfer and thermal expansion in the polysilicon layer. The displacement of actuator is analyzed to be proportional to the square of input voltage. These micro actuator technology can be utilized for the fabrication of MEMS (microelectromechanical system) such as micro relay, which requires large displacement or contact force but relatively slow response.

• Composites Research
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• 제16권2호
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• pp.62-67
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• 2003

Microdroplet 시험법과 전기저항 측정을 이용하여 탄소섬유강화 epoxy-AT-PEI 복합재료의 손상 감지능 및 계면물성평가에 대한 연구를 수행하였다. AT-PEI 함량이 증가함에 따라 기지재료의 파괴인성은 증가하였으며, 이로 인한 에너지흡수 메커니즘에 의해서 계면전단강도 역시 증가하였다. Microdroulet 시험에서 순수 에폭시는 취성파괴 현상을 그리고 15 phr AT-PEI의 경우에는 파괴인성의 증가로 인해 연성 파단 현상을 관찰할 수 있었다. 경화 후에 열 수축에 의한 전기저항 변화는 AT-PEI 함량 증가에 따라 증가하였으며. 가변하중 하에서 순수 에폭시에 함침된 탄소섬유의 같은 응력까지의 도달시간과 기울기는 15 phr AT-PEI의 경우보다 더 빠르고 높았다. 경화과정과 가역적인 하중 하에서의 전기저항 측정으로부터 얻은 결과는 기지재료의 파괴인성과 잘 일치하였다.

• Journal of Microbiology and Biotechnology
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• 제15권1호
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• pp.131-135
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• 2005

Under sulfur deprived conditions, PS II and photosynthetic $O_2$ evolution by Chlamydomonas reinhardtii UTEX 90 are inactivated, resulting in shift from aerobic to anaerobic condition. This is followed by hydrogen production catalyzed by hydrogenase. We hypothesized that the photosynthetic capacity and the accumulation of endogenous substrates such as starch for hydrogen production might be different according to cell age. Accordingly, we investigated (a) the relationships between hydrogen production, induction time of sulfur deprivation, increase of chlorophyll after sulfur deprivation, and residual PS II activity, and (b) the effect of initial cell density upon sulfur deprivation. The maximum production volume of hydrogen was 151 ml $H_2$/l with 0.91 g/l of cell density in the late-exponential phase. We suggest that the effects of induction time and initial cell density at sulfur deprivation on hydrogen production, up to an optimal concentration, are due to an increase of chlorophyll under sulfur deprivation.

• Journal of Korean Neurosurgical Society
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• 제50권5호
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• pp.426-433
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• 2011

Objective : The Histoculture Drug Response Assay (HDRA), which measures chemosensitivity using minced tumor tissue on drug-soaked gelfoam, has been expected to overcome the limitations of in vitro chemosensitivity test in part. We analyzed interim results of HDRA in malignant gliomas to see if the test can deserve further clinical trials. Methods : Thirty-three patients with malignant gliomas were operated and their tumor samples were examined for the chemosensitivity to 10 chosen drugs by HDRA. The most sensitive chemotherapy regimen among those pre-established was chosen based on the number of sensitive drugs or total inhibition rate (IR) of the regimen. The response was evaluated by 3 month magnetic resonance image. Results : Among 13 patients who underwent total resection of the tumor, 12 showed no evidence of disease and one patient revealed progression. The response rate in 20 patients with residual tumors was 55% (3 complete and 8 partial responses). HDRA sensitivity at the cut-off value of more than one sensitive drug in the applied regimen showed a sensitivity of 100%, specificity of 60% and predictability of 70%. Another cut-off value of >80% of total IR revealed a sensitivity of 100%, specificity of 69%, and predictability of 80%. For 12 newly diagnosed glioblastoma patients, median progression-free survival of the HDRA sensitive group was 21 months, while that of the non-sensitive group was 6 months ($p$=0.07). Conclusion : HDRA for malignant glioma was inferred as a feasible method to predict the chemotherapy response. We are encouraged to launch phase 2 clinical trial with chemosensitivity on HDRA.

• Journal of Applied Biological Chemistry
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• 제60권3호
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• pp.249-256
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• 2017

The Monascus azaphilone (MAz) pigment is a well-known food colorant that has yellow, orange and red components. The structures of the yellow and orange MAz differ by two hydride reductions, with yellow MAz being the reduced form. Orange MAz can be non-enzymatically converted to red MAz in the presence of amine derivatives. It was previously demonstrated that mppE and mppG are involved in the biosynthesis of yellow and orange MAz, respectively. However, ${\Delta}mppE$ and ${\Delta}mppG$ knockout mutants maintained residual production of yellow and orange MAz, respectively. In this study, we deleted the region encompassing mppD, mppE and mppG in M. purpureus and compared the phenotype of the resulting mutant (${\Delta}mppDEG$) with that of an mppD knockout mutant (${\Delta}mppD$). It was previously reported that the ${\Delta}mppD$ strain retained the ability to produce MAz but at approximately 10% of the level observed in the wildtype strain. A chemical analysis demonstrated that the ${\Delta}mppDEG$ strain was still capable of producing both yellow and orange MAz, suggesting the presence of minor MAz route(s) not involving mppE or mppG. Unexpectedly, the ${\Delta}mppDEG$ strain was observed to accumulate fast-eluting pigments in a reverse phase high-performance liquid chromatography analysis. A LC-MS analysis identified these pigments as ethanolamine derivatives of red MAz, which had been previously identified in an mppE knockout mutant that produces high amounts of orange MAz. Although the underlying mechanism is largely unknown, this study has yielded an M. purpureus strain that selectively accumulates red MAz.

• 분석과학
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• 제23권4호
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• pp.405-413
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• 2010

축산물(소의 근육 및 간)중에 잔류하는 합성 글루코코티코이드 6종 (betamethasone, dexamethasone, prednisone, prednisolone, methylprednisolone, flumethasone)에 대한 동시분석방법을 확립하였다. 효과적인 기기분석을 위해서 시료는 C18 고체상 카트리지를 사용하여 에틸아세테이트 용매를 사용하여 추출/정제하였다. C18 컬럼을 사용하여 분리한 후 음이온 전기분무 질량분석법의 multiple reaction monitoring 방법을 사용하여 정량 및 정성 분석을 수행하였다. 효과적이고 감도있는 HPLC-MS/MS 분석을 위해서 0.1% 포름산이 포함된 물과 아세토나이트릴이 이동상 용매로 사용되었다. 메트릭스와 약물의 종류에 따라서 검출한계(LOD)는 $0.2-0.1\;{\mu}g$/kg, 정량한계(LOQ)는 $0.8-3.4{\mu}g$/kg 이었으며, 회수율은 89.5-119.6%이었다. 확립된 기존의 방법들에 비해 6종의 글루코코티코이드의 동시분석 방법이 간소화되었고, 좋은 정확도, 정밀도 및 회수율을 나타내었으며, 축산 육류 중에 잔류하는 글루코코티코이드들 분석하는데 사용될 수 있을 것이다.