• 한국해안해양공학회:학술대회논문집
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• 한국해안해양공학회 2003년도 한국해안해양공학발표논문집
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• pp.179-184
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• 2003

It is inevitable for dredging to increase the suspended sediment concentration (SSC) of the ambient waters in some degree, which has the potential to affect the coastal ecosystem in various manners. Thus, quantitative under- standing of dredging-induced sediment loss is essential fur the reliable environmental impacts assessment. (omitted)

• 농업과학연구
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• 제50권4호
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• pp.917-925
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• 2023

Efforts for developing the domestic horse industry in South Korea are evident through the various national policies. Proper management of stables for ensuring the health of horses is essential to sustain the growing equine industry. This study aimed to measure the fine dust emissions in stables based on the type and quantity of bedding used for horses, for establishing guidelines pertaining to bedding use in stables. The stables accommodated 12 horses. Sawdust, wood shavings, wood pellet, and straw were chosen as treatments. Three different quantities (approximately 3, 6, and 9 cm in height) were applied for each type. Fine dust measurements were carried out at three time points, with each measuring period lasting for approximately three weeks. Measurements included PM2.5 and PM10 fine dust levels. The initial analysis revealed that, sawdust with 9 cm bedding had the highest dust levels; approximately 54.6 ㎍/m³, for PM2.5 and 95.3 ㎍/m³, for PM10. Sawdust bedding at the highest quantity (9 cm) exhibited significantly higher initial fine dust emissions. These findings suggest that bedding materials with smaller particle size, such as sawdust and wood shavings, tend to produce finer dust. Initially, the fine dust emissions decreased in all bedding types and quantities, possibly due to the increased moisture content of bedding owing to horse manure production. However, emissions increased subsequently due to ammonia production.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 춘계학술대회
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• pp.197-197
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• 1996

Helicobacter pylori (H. pylori) is a microaerophilic spiral bacterium and infection by it in the human stomach causes gastritis, furthermore, it is considered to be involved in the pathogenesis of peptic ulcers and the development of gastric carcinoma. We assessed the inhibitory activity of new antiulcer drugs against Helicobacter pylori. The activities of new antiulcer agents against Helicobacter pylori strains were determined by the standard agar dilution method with blood agar base #2, supplemented with 5% sheep blood and 4 antibiotics to support growth of these organisms. They were inoculated by multipoint inoculator and incubated at 37$^{\circ}C$ for 3 days under microaerophilic atmosphere. The MIC of antiulcer agents was the lowest concentration that inhibited visible growth of these organisms. According to results of various biochemical tests, these bacteria were identified as Helicobacter pylori strains. And the MIC results showed that the strains were very susceptible to omeprazole and YJA20379s. Some of YJA20379s were more potent than omeprazole. These results suggest that our new antiulcer drugs have potent inhibitory activity against Helicobacter pylori, so that our new antiulcer drugs might be useful for the clinical eradication of gastrointestinal Helicobacter pylori.

• 식품과학과 산업
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• 제50권3호
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• pp.39-50
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• 2017

In order to secure competitiveness of the home meal replacement (HMR) industry from a long-term perspective, development of packaging and processing technologies must be achieved. The development of technology that can secure freshness, nutrition, and taste but secures the shelf life is the key to the future growth of HMR. The future of HMR can be considered in terms of nutrition, environment and safety. From the nutritional point of view, it is expected that development of healthy HMR such as low-salt, low-sugar, low-fat, and high fiber and premium HMR with functional ingredient enhanced, and personalized HMR for silver, infant and patients will be done. And it is expected that development of HMR utilizing environmentally friendly food or local food, development of energy reduction and environmentally friendly disinfection technology, development of environmentally friendly packaging material, and providing information on HMR preparation using QR code and RFID from the environmental and safe point of view.

• 한국군사과학기술학회지
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• 제27권3호
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• pp.387-394
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• 2024

This paper describes a progressive test and evaluation strategy for verification of Korean Fighter eXperimental (KF-X) AESA(Active Electronically Scanned Array) radar development. Three progressive stages of development test and evaluation were officially performed from simulated test conditions to actual operating conditions according to standards: radar function/performance and avionics integration. KF-X AESA radar development is repeatedly verified by progressive stages consisting of five tests: Roof-lab ground test, System Integration Laboratory(SIL) ground test, Flying Test Bed(FTB) test, KF-X ground test, and KF-X flight test. As a result, the risk factor decreases as stages and tests progress. Therefore, development test and evaluation of KF-X AESA radar are successfully performed at low development risk.

• 대한수의학회지
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• 제21권1호
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• pp.41-43
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• 1981

The occurrence of inclusion body hepatitis was confirmed for the first time in Korea from chickens submitted for diagnosis to this Institute from a farm located in the vicinity of Anyang. The chickens showed no specific clinical signs except for moderate anemic conditions. At autopsy, livers were swollen and mottled with numerous stellate subcapsular hemorrhages and necrotic foci. Severe nephritis and catarrhal enteritis were also seen. The most notable microscopic changes were seen in the liver. These included eosinophilic intra-nuclear inclusion bodies in the hepatocyes, massive hemorrhages and necrosis and fatty changes in the liver parenchema.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.5599-5608
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• 2013

With the high morbidity and mortality caused by cancer, finding new and more effective anti-cancer drugs is very urgent. In current research, biotransformation plays a vital role in the research and development of cancer drugs and has obtained some achievements. In this review, we have summarized four applications as follows: to exploit novel anti-cancer drugs, to improve existing anti-cancer drugs, to broaden limited anti-cancer drug resources and to investigate correlative mechanisms. Three different groups of important anti-cancer compounds were assessed to clarify the current practical applications of biotransformation in the development of anti-cancer drugs.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1997년도 춘계학술대회
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• pp.100-100
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• 1997

To treat peptic ulcer diseases, many potent proton pump inhibitors have been developed for suppressing the gastric acid secretion in clinical patients. However, most of these agents have common irreversible mechanisms against H$\^$+/, K$\^$+/-ATPase which might be the cause of hypergastrinemia and ECL cell hyperplasia. Therefore, the development of new reversible inhibitors is prompted. In this study, we investigated the inhibitory mechanism of a newly synthesized proton pump inhibitor, YJA20379-8 using lyophilized hog gastric microsomes. YJA20379-8 inhibited K$\^$+/-stimulated H$\^$+/K$\^$+/-ATPase activity uncompetitively with respect to K$\^$+/, and in the other hand, showed competitive inhibitory pattern with ATP, respectively. From these data, we suggest that YJA20379-8 may be a proton pump inhibitor with a new inhibitory mechanism.

• 아태비즈니스연구
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• 제11권3호
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• pp.169-184
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• 2020

Purpose - This research is intended to analyze the current status and problems of tax benefits in the R&D sector and suggest ways to improve tax credit for research and manpower development expenses when various countries fiercely develop efforts to enhance national competitiveness through increased investment in R&D Design/methodology/approach - This study will examine the current status of the tax support system for domestic and foreign R&D, and suggest improvement measures to expand research and development activities in the future. Findings - First, a plan may be considered to abolish and perpetuate the sunset deadline for tax credit for research and manpower development expenses as in the case of the United States and Japan. This perpetuation can be a proactive measure to actively support long-term R & D investment in companies facing economic decisions under uncertainty. Second, it should be revised to raise the tax credit rate of large corporations, which are shrinking every year, compared to SMEs, so that both large corporations and SMEs can improve their international competitiveness and secure excellent technologies through R & D. Finally, the target technologies for each new growth engine and source technology should be expanded to various fields, including national cybersecurity enhancement technology, aviation engine technology, carbon emission and global cooling technologies, which are areas of interest in major overseas R&D countries, to help active R&D and investment in these areas. Research implications or Originality - This study can find a contribution in comparing and analyzing the national R&D tax support system and presenting improvement measures at a time when the benefits of tax credit for research and manpower development expenses of large companies are decreasing due to frequent tax law revisions and the government's factors of increasing tax revenues. In addition, recent research and development items and research technologies of foreign countries were analyzed by Nature's top 10 major science and technology issues, and advanced technologies that should be applied to target technology areas by new growth engine and source technology were specifically investigated and presented.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 추계학술발표회
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• pp.366-367
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• 2011