• Title/Summary/Keyword: research activities

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Pharmacology of Iridoid: Antimicrobial Activities of Aucubin

  • Lee, Eun-Sook;Ahn, Jung-Wook;Mar, Woong-Chon;Chang, Il-Moo
    • Korean Journal of Pharmacognosy
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    • v.17 no.2
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    • pp.129-133
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    • 1986
  • Antimicrobial activities of aucubin, an iridoid glycoside, were investigated. Gram-positive bacterium, S. aureus appeared to be more sensitive to aucubin's aglucone, aucubigenin than Gram-negative, E. coli did. Antimicrobial activities produced by aucubigenin may result in part from the inhibition of RNA and protein biosyntheses in bacterial cells. The conversion of aucubin iridoid glycoside into aucubigenin, an aglucone, appears to be a prerequisite step to exhibit the antimicrobial activities.

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Non-Value Adding Activities in South African Construction: A Research Agenda

  • Emuze, Fidelis;Smallwood, John
    • Journal of Construction Engineering and Project Management
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    • v.1 no.3
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    • pp.38-44
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    • 2011
  • The central issue in this particular research is the seemingly inadequate achievement of optimum performance in the construction process, either with respect to value for money for the client and the entire construction supply chain or value in terms of the utility derived from built assets in spite of efforts by government and governmental bodies such as the Construction Industry Development Board (cidb) to increase industry performance. Therefore, based upon an extensive review of related literature, the paper reports on effects and causes of non-value adding activities in the construction industry in general, and South African construction in particular. The research findings indicate that activities that can be referred to as non-value activities are not only prevalent, but they can also be held responsible for performance related issues in terms of cost, time, quality and health and safety (H&S) in construction; and the exploration of pluralism in the research methodology may result in a robust model based upon the system dynamics approach.

Anti-Oxidant Activities of Fucosterol from Pelvetia siliquosa

  • Hoon, Jung-Sang;Lee, Sang-Hyun;Lee, Yeon-Sil;Lee, Hye-Seung;Kang, Sam-Sik;Shin, Kuk-Hyun
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.198.2-198.2
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    • 2003
  • The anti-oxidant activities of fucosterol isolated from the marine algae Pelvetia siliquosa were investigated. Fucosterol exhibited a significant decrease in serum transaminase activities elevated by hepatic damage induced by CCl$_4$-intoxication in rats. Fucosterol inhibited the sGOT and sGPT activities by 25.57 and 63.16%, respectively. Fucosterol showed the increase in the anti-oxidant enzymes such as hepatic cytosolic superoxide dismutase, catalase and glutathione peroxidase activities by 33.89, 21.56 and 39.24%, respectively, in CCl$_4$-intoxicated rats. (omitted)

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Enzyme activity changes by intraperitoneal injection of uranium in the carp liver (우라늄 투여후 간조직에서의 효소활성도의 변화)

  • Kim, In-Gyu;Kim, Kug-Chan;Kim, Jin-Kyu;Kim, Sang-Bok;Chun, Ki-Chung;Park, Hyo-Kook;Lee, Kang-Suk
    • Journal of Radiation Protection and Research
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    • v.18 no.2
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    • pp.61-69
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    • 1993
  • We examined various enzyme activity changes by intraperitoneal injection uranium in the carp liver. These enzyme activity changes can be used as biochemical indicators of internal exposure to uranium. The results were followings ; 1) Total protein concentration decreased by intraperitoneal injection in the carp liver. 2) Lysosomal acid pretense and ${\beta}-glucuronidase$ activities increased in the liver until sixth intraperitoneal injection of uranium, but Lysosomal acid phosphatase activities decreased in the liver until the sixth injection of uranium. 3) Alkaline phosphatase activities sharply increased and Glutamate oxaloacetate Transaminase activities steadily decreased in the liver until the sixth injection of uranium. 4) Creatine %kinase activities steadily decreased and malate dehydrogenase activities sharply decreased in the liver after the primary injection of uranium. Any malate dehydrogenase activities was not detected after sixth injection of uranium.

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Antioxidant and Angiotensin I Converting Enzyme Inhibitory Activities of Red Snow Crab Chionoecetes japonicas Shell Hydrolysate by Enzymatic Hydrolysis

  • Yoon, Na Young;Shim, Kil-Bo;Lim, Chi-Won;Kim, Sang-Bo
    • Fisheries and Aquatic Sciences
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    • v.16 no.4
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    • pp.237-242
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    • 2013
  • We investigated the antioxidant and angiotensin I converting enzyme (ACE) inhibitory activities of red snow crab Chionoecetes japonicas shell (RSCS) hydrolysate by enzymatic hydrolysis and its molecular weight cut-off fractions. The RSCS hydrolysate was fractionated through two ultrafiltration membranes of 3 and 10 kDa cut-offs. Three fractions (<3 kDa, 3-10 kDa, and >10 kDa) were evaluated for total amino acid composition, antioxidant activities using 2'-azino-bis[3-ethylbenzthiazoline-6-sulfonic acid] ($ABTS^+$) radical scavenging and superoxide dismutase (SOD)-like activities and reducing power assays, and ACE inhibitory activity using Hou's method. Although all fractions showed activity, the <3 kDa fraction of RSCS hydrolysate exhibited the greatest $ABTS^+$ radical scavenging, SOD-like and ACE inhibitory activities. However, these fractions exhibited low reducing power. These results suggest that the low-molecular-weight enzymatic hydrolysate of RSCS could be used as a functional ingredient to control oxidative stress and ACE activity.

Effects of Polyacetylenes from Panax ginseng on Some Microsomal and Mitochondrial Enzymes

  • Kim, Young-Sook;Kim, Shin-Il;Hahn, Dug-Ryong
    • Korean Journal of Pharmacognosy
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    • v.20 no.3
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    • pp.154-161
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    • 1989
  • Effects of panaxydol, panaxynol and panaxytriol isolated from Panax ginseng C.A. Meyer on some enzyme activities were determined. Activities of ATPase, membrane-bound enzyme from Sarcoma 180 and rat liver were slightly inhibited by panaxydol. Activities of 5'-nucleotidase, membrane-bound enzyme and succinate cytochrome c reductase in mitochonidria from sarcoma 180 and rat livers were significantly inhibited in a dose-dependent manner by panaxynol. The inhibitory effects of panaxydol and panaxynol on succinate cytochrome c reductase activities were more potent than those on 5'-nucleotidase activities and panaxynol was found to be a very potent inhibitor of succinate cytochrome c reductase. Activities of glucose-6-phosphatase in endoplasmic reticulum from Sarcoma 180 and rat livers were not affected by all three polyacetylenes. These results suggested that the inhibitory effects of panaxydol and panaxynol on enzyme activities might contribute to their biological activities.

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The Effects of Ecology Club Mentor Activities of Pre-service Teachers on Elementary Student's Environmental Sensitivity and Environment-friendly Attitudes (초등예비교사의 생태동아리 멘토 활동이 초등학생의 환경감수성 및 환경친화적 태도에 미치는 효과)

  • Lee, Yongseob
    • Journal of the Korean Society of Earth Science Education
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    • v.8 no.3
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    • pp.378-386
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    • 2015
  • This study is to find out that pre-service elementary teacher's the effects of a ecology mentor club activities to the environmental sensitivity and the effects on the environment friendly attitude of elementary school students. This study has been aimed at 25 students of 5th grade in B metropolitan city S elementary school in 2015, B educational University of elementary pre-service teachers 10 people, Elementary School Teachers10 people to apply a ecology club mentor activities to investigate a comment participated in environmental mentor club activities of elementary pre-service teachers and the environmental sensitivity and the effects on the environment friendly attitude of elementary school students. Procedures for this research was the topic for setting ecology club mentor activities of elementary school students, pre-service elementary school teachers receive consultation from field teachers and guide to ecology club mentor activities of elementary school students. Before the ecology club mentor activities, pre-test environmental sensitivity and the environment-friendly attitude of were carried out. After the experiment, post-test of environmental sensitivity and environmental friendly attitude check was carried out. Also, investigate a comment of pre-service elementary teachers participate and guide to ecology club mentor activities of elementary school students. After the experiment results are as follows. First, the ecology club mentor activities of pre-service elementary school teachers are effective to cultivate environmental sensitivity of the elementary school students. Second, the ecology club mentor activities of pre-service elementary school teachers are effective to cultivate eco-friendly attitude of the elementary school students. Third, after ecology club mentor activities of elementary school students, pre-service elementary school teachers now have a very good feeling. Based on these results, suggestions for further research are as follows. First, the variety of ecological club programs target to elementary school students are needed. Second, there is a need for continuing research on the ecology club activities.

Study on Elderly Leisure Activities and Life Satisfaction to Whether an Elderly Has a Spouse or Not (배우자 유무에 따른 노인의 여가활동 및 생활만족도에 관한 연구)

  • Lim, Chang-Hee;Han, Su-Jin
    • Journal of Family Resource Management and Policy Review
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    • v.12 no.3
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    • pp.23-43
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    • 2008
  • This research investigates the effect of leisure activities on lifestyle satisfaction of senior citizens. The target of this research is 202 people over 60 years of age who live in Seoul. Collected data was analyzed using frequency, percentage, average, T-test, one-way ANONA, and logistic regression analysis. SPSS and the Excel PC Program were used for the analysis. The following is the summary of the result of this research. First - in terms of participation in leisure activities: more active participation is observed with the elderly who have a spouse than with those who do not in every kind of leisure activity (except for the pastime activities). Second - all of the variables indicating the level of satisfaction from activities of the seniors who have a spouse are by far higher than those of the elderly who have no spouse. Third - the leisure activities and the satisfaction from the activities prove affective variables on whether they have a spouse or not. Notably, the religious leisure activities are enjoyed more by those senior citizens who are married. Comparatively, the unmarried senior citizens participate more actively in recreational and pastime leisure activities. This study suggests various practical means to promote leisure activities to the elderly and to raise the level of satisfaction received from those activities, as well as to help those who are concerned with understanding and improving lifestyle satisfaction of the elderly population. Nonetheless, this analysis is limited due to the restriction on the number of objects and samples studied. Therefore, studies to analyze leisure activities by regions in order to account for a more balanced set of systematical tools should follow.

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Linking Knowledge Management Activities to Innovation Capability : Focused on IT Service Industry (지식 경영 활동의 혁신 역량으로의 연계 : IT 서비스 산업 중심으로)

  • Kim, Byoungsoo;Hau, Yong-Sauk;Han, Ingoo;Lee, Heeseok
    • Knowledge Management Research
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    • v.11 no.1
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    • pp.97-113
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    • 2010
  • Given the large investment and prevalence of knowledge management (KM) in organizations, it has become important to analyze the effects of KM activities on organizational performances. A theoretical framework is proposed to investigate the impact of KM activities on innovation capabilities in the IT service industry. This study considers KM activities as the major determinant that enhances absorptive capacity. KM activities enhance employees'ability to obtain external knowledge, resulting in increasing intellectual capital. Thus, this study proposes that absorptive capacity plays a mediating role between KM activities and innovation capability. Additionally, this study investigates the key antecedents of KM activities that promote employees' knowledge sharing. Based on prior studies on KM, this study posits KM team activities and top manager support as KM activities. The proposed research model was tested by using survey data collected from 556 employees in the IT service industry. PLS (partial least squares) was employed for the analysis of the data. The findings of this study showed that KM activities and absorptive capabilities play a significant role in enhancing service innovation and process innovation in the IT service industry. The results also shed light on the mediating role of absorptive capacity between KM activities and innovation capability. Moreover, both KM team activities and top manager support serve as the salient antecedents of promoting employees' knowledge sharing.

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Research Related Activities and Its Related Factors in Clinical Nurses (임상간호사의 연구관련 활동 실태와 관련요인)

  • Yang Young-Hee;Gu Mee-Ock
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.12 no.3
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    • pp.421-429
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    • 2005
  • Purpose: This study was don(B to describe research-related activities and attitudes toward research, barriers to and support needs for undertaking research in clinical nurses. Method: Data were collected by a questionnaire from 238 clinical nurses with over one year clinical experience working at 2 university hospitals. Results: Research related activities included courses or lecture about Nursing Research 85.7%, journal reading at least once every 2 to 3 months 30.0%, memberships in academic societies 29.4%, participation in academic conferences 45.0%, conducting research 45.4%, research utilization 24.6%. The score for attitudes toward research was 3.08(range 1-5). The score of barriers to undertaking research was 3.37(1-5) and the score for support needs for undertaking research 4.14(1-5). Attitudes toward research significantly correlated with barriers to undertaking research(r=.- 36, p=.000). Barriers to undertaking research significantly correlated with support needs for conducting research(r=.23, p=.000). Nurses with experience in conducting research had more negative attitudes toward research(t=-2.130, p=0.034) and more barriers to undertaking research than those without experience in conducting research (t=2.194, p=0.029). Conclusion: These results suggest that it is necessary to increase positive attitudes toward research in clinical nurses and nursing organizations need to provide strong supports for nurses conducting research.

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