• Clinical and Experimental Reproductive Medicine
• /
• v.36 no.2
• /
• pp.129-136
• /
• 2009

The incidence of ectopic pregnancy is increased since in vitro fertilization-embryo transfer (IVF-ET) has started. And because of the possibility of combined pregnancy after IVF-ET, bilateral adnexal area and other portion of pelvis should be examined carefully by transvaginal ultrasonography during follow-up period. The rate of combined pregnancy after IVF is estimated to be as high as 0.2~1%. Since the incidence of combined pregnancies is markedly higher with IVF, special attention to this possibility after ET is warranted. According to a recent report, the occurrence of interstitial pregnancy is estimated to be 1:3600 for all pregnancies achieved with IVF. The prevalence of interstitial pregnancies is 2~4% of ectopic pregnancies. Interstitial pregnancies tend to be diagnosed later than most other ectopic pregnancies, and if uterine rupture occurs, the resulting hemorrhage can be severe. Currently, about 2% to 3% of interstitial pregnancies are thought to carry a maternal death, which is twice that of other tubal gestations. We report a case of simultaneous left tubal and right interstitial pregnancies after IVF-ET with a brief review of literature.

• Tuberculosis and Respiratory Diseases
• /
• v.63 no.3
• /
• pp.289-293
• /
• 2007

Lymphangioleiomyomatosis (LAM) is a rare disease that affects females of reproductive age. It is characterized by the abnormal proliferation of smooth muscle cells in the lung and along the axial lymphatics. We report a case of lymphangioleiomyomatosis presenting as a lung mass. The patient visited the emergency room because of dyspnea upon exertion. The chest X-ray showed a lung mass in the right lower lung field and a pneumothorax in the left lung. Chest computed tomography revealed a $5{\times}3cm$ sized mass in the right lower lobe and multiple thin-walled small cysts scattered in both lungs. Transbronchial biopsy of the lung mass was performed. The biopsy specimen showed atypical smooth muscle cell proliferation and cystic dilatation of the terminal bronchioles, which confirmed the diagnosis of lymphangioleiomyomatosis. To the best of our knowledge, this is the first case of lymphangioleiomyomatosis presenting as a lung mass.

• Korean Journal of Occupational Health Nursing
• /
• v.7 no.1
• /
• pp.55-64
• /
• 1998

In order to investigate and compare the health risk factors of nurses in the operating room(OR nurse) and ward (WARD nurse), the questionnaire survey for subjective symptoms was carried out on 553 nurses(132 OR nurses and 421 WARD nurses) who were employed at seven hospital. The self-administered questionnaries were composed of low back pain, subjective fatigue symptoms, musculo-skeletal symptoms, psychological stress and reproductive function. The results were as follows : 1. In the type of working posture and working environment, there were significant difference between two groups for working posture, waist form, height of working table, satisfaction of chair, lifting & carring. 2. Job satisfaction, duration of work, height of working table, satisfaction of chair, lifting & carring were significantly associated the low back pain. 3. In the complaints of subjective fatigue symptoms, the total mean score was higher in OR nurse than WARD nurse, but there was not significant. The items that the mean score of OR nurse was significantly higher than WARD nurse were 'head feels muddled', 'apt to forget', 'feel choky'. 4. In the complaints of musculo-skeletal syrrptoms, the total mean score was higher in OR nurse than WARD nurse, but there was not significant. The item that the mean score of OR nurse was significantly higher WARD nurse was 'wrist discomfort or pain'. 5. The comparison of spontatenous abortion in married nurses who had the experience of pregnancy were significantly associated the stress risk group. 6. In all of OR and Ward nurses, the job satisfaction is associated with subjective fatigue symptoms, musculo-skeletal symptoms, and stress. In conclusion, it suggested that working posture, working environment, stress, and job satisfaction were health risk factors of nurses working in the operating room. Further prospective intervention studies should be conducted to educate right working posture, improve of working environment, decrease of stress, and increase of job satisfaction.

• Korean Journal of Acupuncture
• /
• v.29 no.2
• /
• pp.200-215
• /
• 2012

Objectives : The purpose of this study is to investigate the differences of pulse wave parameter between the non delivery group (single women with no childbirth experience) and the delivery group (married women who gave birth(s) in delivery). Methods : Sixty one healthy (non delivery) nulliparous women and fifty three delivery women participated in this study. We used 3 dimensional pulse analyser(3D MAC, DAEYOMEDI co., Korea), which measures radial pulse waveform non-invasively by way of tonometry method at 5 different applied pressure levels. From 114 subjects enrolled, pulse wave parameters were measured on the six locations of Chon, Kwan and Cheok of each hands. Results : Delivery group's pulse showed larger values in the following pulse wave parameters (Energy, Ap, RAI, As, Aw, h1, h2, h4, h4/h1, t, t1, t2, t4, Wm, Wm/t). Non delivery group's pulse indicated larger values in the pulse wave parameters such as Energy of left Chon, difference pulse energy between left and right hand, Ad, h5, h5/h1, t5. Conclusions : According to the analysis result, delivery group's pulse has bigger values in most part of pulse wave parameters, especially in Kwan and Cheok which correspond to Liver, Kidney, and Myeong-mun. We interpret these results that delivery women are more mature and stable in reproductive organs than non delivery group, as they have experienced delivery(deliveries) and child-caring through married life.

• Journal of Preventive Medicine and Public Health
• /
• v.43 no.2
• /
• pp.131-137
• /
• 2010

Objectives: Bisphenol A diglycidyl ether (BADGE) is a liquid compound obtained by condensation of two molecules of epichlorohydrin with one molecule of bisphenol A. General and reproductive toxicity with BADGE has been reported higher than 1000 mg/kg/day. This study was performed to show the effects of acute exposure to BADGE below 1000 mg/kg/day on the testis in adult male rats. Methods: BADGE was administered by gastric lavage in a single dose of 500, 750, 1000, and 2000 mg/kg/day in 8-week old male SPF Sprague-Dawley rats. The right testis was processed for light microscopic analysis. The left testis was homogenized and spermatids were counted to determine the daily sperm production and daily abnormal sperm production. The sperm count, sperm motility, and incidence of abnormal sperm were estimated in the epididymis. In testicular sections, the seminiferous tubules were observed for qualitative changes. The progression of spermatogenesis was arbitrarily classified as full-matured, maturing, and immature. The specimen slide was observed at 3 points and 10 seminiferous tubules were evaluated at each point. Results: The male rats exposed to single oral dose of BADGE at 750, 1000, and 2000 mg/kg/day were significantly increased the number of immature and maturing sperm on the testis. There were no significant differences with respect to sperm head count, sperm motility, and sperm abnormality in the BADGE treatment groups. Conclusions: These results suggest that single oral exposure of BADGE 750 mg/kg/day can affect adult male testis development.

• Toxicological Research
• /
• v.21 no.1
• /
• pp.23-29
• /
• 2005

A developmental study of CONP01, a new antiarthritic agent, was conducted in Sprague-Dawley rats. Dosage of CONP01 0, 111, 333, and 1000 mg/kg/day were administered to dams orally from day 6 to day 16 of gestation. Two-third of dams per group were subjected to caesarean section on day day 20 of pregnancy for examination of their fetuses, and the remaining one-third of dams per group were allowed to deliver naturally for postnatal examination of their offspring. There was no change in the dams body weights, food consumptions, specific clinical sings and gross findings. There was significant decrease only in the absolute and relative weights of right ovary in 111 mg/kg treatment group, when compared with the vehicle control, whereas other organ weights were not changed. Moreover, no increase in the frequencies of external, visceral and skeletal malformation of fetuses were observed in the treated groups. These results suggest that the oral NOAEL (no observed adverse effect level) of CONP01 may be over 1,000 mg/kg in dams and fetuses of rats.

• Reproductive and Developmental Biology
• /
• v.34 no.3
• /
• pp.123-126
• /
• 2010

The purpose of present study was to analyze mineral contents in various tissues and investigate theirs relation with bone mineral density (BMD) in rats. Fifteen Sprague-Dawley rats were fed standard diet for 4 weeks. Body weight gain, feed intake, and feed efficiency ratio were 41.00 g/week, 171.15 g/week, and 0.24 respectively. Among 12 minerals in serum, Ca is the highest with 6.86 mg/dl. Serum Mg, Se, and Cu were 2.52 mg/dl, 0.23 mg/dl and 0.22 mg/dl respectively. Mg contents in liver, spleen, and kidney were $246.36\;{\mu}/g$, $105.01\;{\mu}/g$, and $273.38\;{\mu}/g$ respectively. Tibia contents of Ca, Mg, Zn, Fe and V were 194.91 mg/g, 23.10 mg/g, 0.60 mg/g, 0.35 mg/g and 0.14 mg/g respectively. BMDs of right tibia and spine were 122.04 mg/cm and $153.61\;mg/cm^2$. There were significantly positive correlations between tibia BMD and Se (p<0.05), tibia BMD and V (p<0.01), spinal BMD and V(p<0.05), respectively. It's expected that these results are used as a reference data in following study to elucidate physiological function of minerals.

• Reproductive and Developmental Biology
• /
• v.32 no.2
• /
• pp.123-126
• /
• 2008

The objective of this study was to determine the potential hazardous effects of sorting process by flowcytometry on the quality of boar spermatozoa by flowcytometer. Freshly collected boar semen was diluted and divided into two groups; control none sorted and sorted. Sperms in sorted group were processed with flowcytometer for cell sorting with $100\;{\mu}M$ nozzle under the 20 psi pressure. Measurements on each parameter were made at two time points, 0hr (right after sorting) and 24 hr post sorting. Although there was a tendency of lower viability in sorted group than none sorted control group, the percentage of live cells in control ($75.83{\pm}6.92\;&\;59.53{\pm}10.34$) was not significantly different from sorted ($59.70{\pm}7.37\;&\;43.97{\pm}3.76$) at both 0 and 24 hr post sorting. However, sorted sperm showed significantly lower mitochondrial function compared to the control at both 0 h ($79.37{\pm}3.22\;vs.\;63.50{\pm}10.05$) and 24 hr ($67.27{\pm}3.22$ vs. $46.97{\pm}5.37$) time points (p<0.007). Sperm DNA fragmentation rate was significantly lower in control ($22.0{\pm}7.04$) than that of sorted ($32.27{\pm}7.49$) at 24 hr time point (p<0.0002). Taken together, these data suggested thatsorting process by flowcytometer may have influenced sperm motility rather than viability. Also high speed sperm sorting by flowcytometer has significant effects on DNA fragmentation on elapsed time after sorting.

• Asian-Australasian Journal of Animal Sciences
• /
• v.18 no.3
• /
• pp.308-313
• /
• 2005

Logistic Regression Analysis was used to compute the odds ratio (OR) and probability of conception of Holstein dairy cows of AL-MARAIE company. Data consisted of 103,778 reproductive records collected from three farms in the central region in the Kingdom of Saudi Arabia. Records were classified according to lactation number, season of calving and milk level. At first lactation, OR of first service was 0.63 of other services and probability of pregnancy from first services was 0.39. Odds ratio increased to 1.72 at fourth lactation or probability of conception reached 0.63. The probability of conception increased from 0.39 for cows inseminated at first services to 0.75 at fifth service insemination. Odds ratio of cows calving in winter were higher than those calving in summer. Odds ratio of conception of low producing cows is about twice as likely to occur from first service as from other services. However, OR of conception of high producing cows was higher than one (probability=0.56) from first service and increased to 1.63 (probability=0.65) from third service. Odds ratio was in favor of the right uterus horn where probability of conception from first service was slightly greater than 50% in first and second lactations and less than 50% in favor of left horn in later lactations.

• Women's Health Nursing
• /
• v.5 no.1
• /
• pp.65-79
• /
• 1999

The purpose of this study was to figure out a direction for midwifes' expanded roles for integrative woman's health care focused on health promotion & maintenance and primary prevention of women's health disorders including family health in the new millenium as a primary women's health practitioner. Data sources used for analysis were the book published from International Confederation of Midwives including role, code, situation and others from the international aspects : the empirical data from direct contact by participation in the ICM held in Manila, Philipine, May 22-26, 1999 : and documentation of Korean Midwives Association. Historical and current changing perspectives toward woman's health & nurse-midwifery and the reality women's health & nurse-midwifery and the reality of expand role that should be acquired toward the new millenium are discussed. In conclusion, Nurse-midwives are the very primary women's health care providers who can provide not only the exact needs of women who have health related problems, which are developed in the unique socio-cultural context women are belonged to, but also reproductive affairs including labor and delivery as it was midwive's traditional role, not just as practitioner, educator, counselor but conscious raiser for women's right. Futhermore, for this, thorough preparation through various kind of active and contemplated approach such as remodeling roles and education and continuing education system, training for high skilled & technical action, making laws and policy, and others is absolutely required.