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A Case of Lymphangioleiomyomatosis Presenting as a Lung Mass  

Park, Seon Cheol (Department of Internal Medicine, Yonsei University College of Medicine)
Park, Byung Hoon (Department of Internal Medicine, Yonsei University College of Medicine)
Shin, Sang Yun (Department of Internal Medicine, Yonsei University College of Medicine)
Jeon, Han Ho (Department of Internal Medicine, Yonsei University College of Medicine)
Chung, Kyung Soo (Department of Internal Medicine, Yonsei University College of Medicine)
Park, Jun Chul (Department of Internal Medicine, Yonsei University College of Medicine)
Jeong, Jaeheon (Department of Internal Medicine, Yonsei University College of Medicine)
Kwon, Ji Eun (Department of Pathology, Yonsei University College of Medicine)
Park, Moo Suk (Department of Internal Medicine, Yonsei University College of Medicine)
Kim, Se Kyu (Department of Internal Medicine, Yonsei University College of Medicine)
Chang, Joon (Department of Internal Medicine, Yonsei University College of Medicine)
Kim, Sung Kyu (Department of Internal Medicine, Yonsei University College of Medicine)
Kim, Young Sam (Department of Internal Medicine, Yonsei University College of Medicine)
Publication Information
Tuberculosis and Respiratory Diseases / v.63, no.3, 2007 , pp. 289-293 More about this Journal
Abstract
Lymphangioleiomyomatosis (LAM) is a rare disease that affects females of reproductive age. It is characterized by the abnormal proliferation of smooth muscle cells in the lung and along the axial lymphatics. We report a case of lymphangioleiomyomatosis presenting as a lung mass. The patient visited the emergency room because of dyspnea upon exertion. The chest X-ray showed a lung mass in the right lower lung field and a pneumothorax in the left lung. Chest computed tomography revealed a $5{\times}3cm$ sized mass in the right lower lobe and multiple thin-walled small cysts scattered in both lungs. Transbronchial biopsy of the lung mass was performed. The biopsy specimen showed atypical smooth muscle cell proliferation and cystic dilatation of the terminal bronchioles, which confirmed the diagnosis of lymphangioleiomyomatosis. To the best of our knowledge, this is the first case of lymphangioleiomyomatosis presenting as a lung mass.
Keywords
Lymphangioleiomyomatosis; Lung mass;
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