• Title/Summary/Keyword: relaxation function

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Vasorelaxing Effect of Isoflavonoids Via Rho-kinase Inhibition in Agonist-Induced Vasoconstriction (Isoflavonoids에 의한 혈관이완효과에 있어 Rho-kinase의 역할)

  • Je, Hyun-Dong
    • YAKHAK HOEJI
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    • v.50 no.4
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    • pp.293-299
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    • 2006
  • The aim of present study was to investigate the possible influence of Rho-kinase inhibition on the plant-derived estrogen-like compounds-induced arterial relaxation. Agonist- or depolarization-induced vascular smooth muscle contractions involve the activation of Rho-kinase pathway. However there are no reports addressing the question whether this pathway is involved in genistein-or daidzein-induced vascular relaxation in rat aortae precontracted with phenylephrine or thromboxane $A_2$ mimetic U-46619. We hypothesized that Rho-kinase inhibition plays a role in vascular relaxation evoked by genistein or daidzein in rat aortae. Endothelium-intact and denuded arterial rings from male Sprague-Dawley rats were used and isometric contractions were recorded using a computerized data acquisition system. Genistein concentration-dependently inhibited phenylephrine or thromboxane $A_2-induced$ contraction regardless of endothelial function. Surprisingly, in the agonists-induced contraction, similar results were also observed in aortae treated with daidzein, the inactive congener for protein tyrosine kinase inhibition, suggesting that Rho-kinase might act upstream of tyrosine kinases in phenylephrine-induced contraction. In conclusion, in the agonists-precontracted rat aortae, genistein and daidzein showed similar relaxant response regardless of tyrosine kinase inhibition or endothelial function.

NUMERICAL SIMULATIONS FOR THE CONTRACTION FLOW USING GRID GENERATION

  • Salem, S.A.
    • Journal of applied mathematics & informatics
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    • v.16 no.1_2
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    • pp.383-405
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    • 2004
  • We study the incomprssible Navier Stokes equations for the flow inside contraction geometry. The governing equations are expressed in the vorticity-stream function formulations. A rectangular computational domain is arised by elliptic grid generation technique. The numerical solution is based on a technique of automatic numerical generation of acurvilinear coordinate system by transforming the governing equation into computational plane. The transformed equations are approximated using central differences and solved simultaneously by successive over relaxation iteration. The time dependent of the vorticity equation solved by using explicit marching procedure. We will apply the technique on several irregular-shapes.

Bioactivity of an Extract of Lespedezea Cuneata G. Don to Rabbit Corpus Cavernosum Smooth Muscle Tone (야관문(Lespedezea cuneata G. Don) 추출물이 토끼 음경해면체 평활근에 미치는 생리활성)

  • Chung, Young-Ho;Lim, Chi-Hwan
    • Korean Journal of Agricultural Science
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    • v.32 no.1
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    • pp.63-70
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    • 2005
  • The extracts in n-hexane layer from Lespedezea cuneata G. Don exelled at sexual activity according to in vitro experiment using biopsy of rabbit corpus cavernosum to investigate effects on sexual function. The extracts were injected into 9 samples at $10{\mu}l$. The lowest relaxation was showed at sample C, $4.8{\pm}1.4%$ and the highest relaxation was showed at sample A, $20.2{\pm}6.0%$. The relaxation by every sample, except sample C and G-1, were higher than by $10^{-7}M$ ACh, $7.8{\pm}5.1%$, and their effects were above 10%. Also, the extracts were injected into 9 samples at $15{\mu}l$. The lowest relaxation was showed at sample C, $15.4{\pm}9.7%$ and the highest relaxation was showed at sample J, $54.8{\pm}9.7%$. The relaxation by sample A and D was as much as by $10^{-6}M$ ACh, $28.0{\pm}20.1%$. The relaxation by sample H was $41.9{\pm}7.3%$. The relaxation by sample J was $54.8{\pm}9.7%$ and it was higher than by $10^{-5}M$ ACh, $53.9{\pm}25.9%$. Also, the extracts were injected into 9 samples at $20{\mu}l$. The lowest relaxation was showed at sample E, $28.9{\pm}0.6%$ and it was a little higher than by $10^{-6}M$ ACh. The relaxation by sample G was as much as by $10^{-5}M$ ACh. The two higher relaxation were showed at sample H, $99.4{\pm}16.0%$ and J, $95.7{\pm}7.2%$, and their relaxation against contraction reaction by PhE were near 100%. Experiment by sample I was not performed for lack of sample amount.

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FUNDAMENTAL PARAMETERS OF NGC 2509 BASED ON 2MASS DATA

  • Tadross, A.L.
    • Journal of The Korean Astronomical Society
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    • v.38 no.3
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    • pp.357-363
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    • 2005
  • A deep stellar analysis is introduced for the poorly studied open cluster NGC 2509. The Near-IR database of the digital Two Micron All Sky Survey (2MASS) has been used to re-estimate and refine the fundamental parameters of the cluster, i.e. age, reddening, distance, and diameter. As well as, luminosity function, mass function, total mass, relaxation time, and mass segregation of NGC 2509 have been estimated here for the first time..

A study on relaxation of thermal stresses of heat-resistant systems (열차단 시스템에 있어서의 열응력 완화에 대한 연구)

  • Choi, Deok-Kee;Kim, Chang-Soo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.22 no.1
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    • pp.16-22
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    • 1998
  • This paper addresses a method which can be used for analyzing thermal stresses of a functionally graded material(FGM) using semi-analytical approach. FGM is a nonhomogeneous material whose composition is changed continuously from a metal surface to a ceramic surface. An infinite one dimensional FGM plate is considered. The temperature distribution in the FGM is obtained by approximate Green's function solution. To expedite the convergence of the solutions, alternative Green's function solution is derived and shows good agreement with results from finite difference method. Thermal stresses are calculated using temperature distribution of the plate.

Wide-Band Ultrasonic Spectroscopy in Albumin Aqueous Solution (단백질 알부민 수용액의 광대역 초음파 스펙트로스코피)

  • Kim, Jeong-Koo;Bae, Jong-Rim
    • Journal of radiological science and technology
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    • v.30 no.2
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    • pp.161-165
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    • 2007
  • Ultrasonic absorption spectrum in bovine serum albumin aqueous solutions have been measured at $20^{\circ}C$ over the broad frequency range $0.2{\sim}1,000\;MHz$ at pH 7. The absorption spectrum observed at neutral pH was successfully analyzed with the distribution of relaxation time assuming a mirror-image curve of the Davidson-Cole function. This distribution function suggests that hydration of BSA molecules is responsible for the absorption.

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A Study of A Nonlinear Viscoelastic Model for Elastomeric Bushing in Torsional Mode (일래스토메릭 부싱의 회전방향 모두 비선형 점탄성 모델연구)

  • Lee, Seong-Beom
    • Journal of the Korean Society for Precision Engineering
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    • v.16 no.2 s.95
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    • pp.194-200
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    • 1999
  • An elastomeric bushing is a device used in automotive suspension systems to cushion the force transmitted from the wheel to the frame of the vehicle. A bushing is an elastomeric hollow cylinder which is bonded to a solid metal shaft at its inner surface and a metal sleeve at its outer surface. For axial motion case, the relation between the force applied to the shaft and their relative displacement was considered. In this paper, the relation between the moment applied to the shaft and their relative deformation(angle of rotation) is considered for the torsional motion case. Numerical solutions of the boundary value problem represent the exact bushing response for use in the method for determining the moment relaxation function of the bushing. Solutions also allow for comparison between the exact moment-deformation behavior and that predicted the proposed model. It is shown that the predictions of the proposed moment-deformation relation are in very good agreement with the exact results.

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ENERGY DECAY FOR A VISCOELASTIC EQUATION WITH BALAKRISHNAN-TAYLOR DAMPING INVOLVING INFINITE MEMORY AND NONLINEAR TIME-VARYING DELAY TERMS IN DYNAMICAL BOUNDARY

  • Soufiane Benkouider;Abita Rahmoune
    • Communications of the Korean Mathematical Society
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    • v.38 no.3
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    • pp.943-966
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    • 2023
  • In this paper, we study the initial-boundary value problem for viscoelastic wave equations of Kirchhoff type with Balakrishnan-Taylor damping terms in the presence of the infinite memory and external time-varying delay. For a certain class of relaxation functions and certain initial data, we prove that the decay rate of the solution energy is similar to that of relaxation function which is not necessarily of exponential or polynomial type. Also, we show another stability with g satisfying some general growth at infinity.

Pore Water Pressure Behavior due to Undrained Creep of Saturated Clay (포화점성토의 비배수 CREEP 성질에 의한 공극수압의 거동)

  • 강우묵;조성섭;지인택
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.30 no.3
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    • pp.38-50
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    • 1988
  • carried out to present a rheology model which is able to treat time-dependent properties of clay. The results were summarized as follow ; 1. The slope (a(e1)) of deviator stress in strain rate test was independent on axial strain, and pore water pressure was decreased with increment of strain rate. 2. The pore water pressure in a stress relaxation condition was not changed when the strain rate before stress relaxation was 0.05%/min., but it was increased with increment of time when the strain rate before stress relaxation was 0.2%/min 3. The greater the stress condition (q/qmax) and the strain rate before creep test became, the greater the increment rate of axial strain in creep test became. 4. SEKIGUCHI's constitutive equation was slightly overpredicted while empirical equation proposed in the study was well coincided with measured values. 5. The constitutive equation induced by a strain function could be dealed with a behavior of the pore water pressure increased with increment of elapsed time after primary consolidation.

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Extraction of the 3-Dimensional Information Using Relaxation Technique (Relaxation Techique을 이용한 3차원 정보의 추출)

  • Kim, Yeong-Gu;Cho, Dong-Uk;Choi, Byeong-Uk
    • Proceedings of the KIEE Conference
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    • 1987.07b
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    • pp.1077-1080
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    • 1987
  • Images are 2-dimensional projection of 3-dimensional scenes and many problems of scene analysis arise due to inherent depth ambiguities in a monocular 2-D image. Therefore, depth recovery is a crucial problem in image understanding. This paper proposes modified algorithm which is focused on accurate correspondnce in stereo vision. The feature we use is zero-crossing points and the similarity measure with two property evaluation function is used to estimate initial probability. And we introduce relaxation technique for accurate and global correspondence.

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