• 한국습지학회지
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• 제9권1호
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• pp.79-89
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• 2007

This paper provides a comprehensive overview of the present status of several environmental problems caused by emerging toxic substances such as persistent organic pollutants (POPs), endocrine disrupting chemicals (EDCs), and arsenic in various environmental media in Vietnam. Monitoring data reported during the 1990s demonstrated elevated contamination of DDTs in most of these compartments in Vietnam. Studies in frame of the Asia-Pacific Mussel Watch Program revealed that fish, mussels and resident birds from Vietnam contained higher concentrations of DDTs as compared to other countries in region, suggesting the role of Vietnamese environment as a significant emission source of DDT in the Southeast Asian region. The estimated dietary intakes of PCBs and DDTs for Vietnamese were relatively high among Asian developing countries, suggesting potential risk for humans posed by thesechemicals. Widespread contamination of some endocrine active compounds such as alkylphenols and phthalates was observed at various sites along the coasts of northern and middle Vietnam. The presence of significant source of bisphenol-A along Red River estuary was revealed with the concentrations comparable to those reported for developed nations. A case study on seasonal variation of alkylphenols and phthalates in surface water of river delta and estuary of north and middle Vietnam indicated the differences in distribution of these compounds between dry and rainy seasons. Higher concentrations of alkylphenols and phthalates were found in dry season in estuary; while the contrasting pattern was observed in the river delta, showing elevated residues in rainy season. This result suggests the different behavior of alkylphenols and phthalates in river delta and coastal environment. From ecotoxicological perspectives, concentrations of bis-phenol A and di(2-ethylhexyl)phthalates [DEHP] in surface water from some locations in Vietnam exceeded the guideline values for Ecotoxicological Effects and the Environmental Risk Limit, respectively, suggesting potential for toxic implications on aquatic wildlife. Widespread and elevated arsenic contamination was discovered inour recent surveys in groundwater in a large area of suburban areas of Hanoi city, the capital of Vietnam. The most recent investigation in 4 villages showed about more than 50 % of groundwater samples contained As concentrations exceeding 50 g/L (the WHO and Vietnamese standard). In particular, in Son Dong villages, 58 % of samples analyzed contained As concentrations higher than 200 g/L. Good correlations were found in As concentrations in water and hair and urine of peoples in corresponding families, suggesting the chronic exposure to As by people living in As-contaminated ground water areas. In Son Dong village, As levels in hair (mean: 1.7 mg/kg dry wt) and urine (g/g creatinine) exceeding the reference values recommended by WHO, suggesting potential for human risk posed by long term accumulation of As in human body. Future studies should be focused on the time trends of POPs and EDCs in biota in Vietnam in order to predict future trend of contamination and to reveal new clues for understanding possible toxic impacts on aquatic organisms. The issues of arsenic contamination in groundwater and their chronic toxic implications on human health should be systematically investigated in the future.

• 한국식품저장유통학회지
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• 제22권4호
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• pp.559-566
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• 2015

본 연구에서는 곡류 중 트리코테센류 곰팡이독소인 T-2 독소 및 HT-2 독소의 LC-MS/MS 분석방법을 검증하고 국내 유통 곡류 중 T-2 독소 및 HT-2 독소의 오염실태를 파악하였다. 곡류 중의 T-2 독소 및 HT-2 독소를 분석하기 위해, 염화나트륨을 포함한 90% 메탄올 용액으로 추출, 원심분리, 여과, 4% 염화나트륨용액으로 희석하고, 원심분리한 후, 여과한 후 면역친화성칼럼에 의해 정제한 시료를 LC-MS/MS 동시정량 분석하였다. T-2 독소 및 HT-2 독소의 검출한계 및 정량한계는 각각 $0.5{\mu}g/kg$ 및 $1.5{\mu}g/kg$ 얻었다. matrix-matched 표준 검량식에서 상관계수 0.99 이상의 직선성을 얻었으며, T-2독소와 HT-2 독소 2배에서 10배의 정량한계로 표준용액을 첨가한 시료에서 회수율은 T-2독소와 HT-2 독소 각각 $100.6{\pm}7.2%$, $96.8{\pm}9.4%$로 EU 가이드라인에서 제시하는 유효성 기준을 만족하였다. LC-MS/MS 정량법을 이용하여 국내 곡류 9품목 115건에 대해 T-2 독소와 HT-2 독소의 오염도를 조사하여 본 결과, 전체 곡류 115건 중에서 T-2 독소는 83건, HT-2 독소는 93건 검출되었으며 오염도는 T-2 독소는 N.D~37.1 ug/kg, HT-2 독소는 N.D~5.4 ug/kg 으로 낮은 수준이었으며, 오염도는 유럽기준치($100{\mu}g/kg$)이내 이었다. 본 연구에서 개발된 곡류 중 T-2 독소 및 HT-2 독소에 대한 분석법은 향후 우리나라 곡류 중 곰팡이독소 안전관리를 위한 시험법으로 활용가능하며, 오염도 자료는 안전성 평가의 기초자료로 활용이 가능할 것으로 사료된다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제41권
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• pp.33.1-33.7
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• 2019

Background: The concept of the ideal morphology for the alveolar bone form is an important element to reconstruct or restore the in maximizing esthetic profile and functional alveolar bone restoration. The purpose of this preliminary study is to evaluate the normal alveolar bone structure to provide the standard reference and guide template for use in diagnosing for implant placement, determining the correct amount of bone augmentation in actual clinical practice and producing prostheses based on three-dimensional imaging assessment of alveolar bone. Methods: This study was included 11 men and 11 women (average age, 22.6 and 24.5 years, respectively) selected from among 127 patients. The horizontal widths of alveolar bone of maxilla and mandible were measured at the crestal, mid-root, and root apex level on MDCT (multi-detector computed tomography) images reconstructed by medical imaging software. In addition, tooth dimensions of the central incisors, canines, second premolars, and first molars of maxilla and mandible, including the horizontal width of the interdental alveolar bone crest, were also measured and statistically analyzed. Results: The horizontal alveolar bone width of the palatal side of maxilla showed a distinct increment from the alveolar bone crest to the apical region in both anterior and posterior areas. The average widths of the maxillary alveolar ridge were as follows: central incisor, 7.43 mm; canine, 8.91 mm; second premolar, 9.57 mm; and first molar, 12.38 mm. The average widths of the mandibular alveolar ridge were as follows: central incisor, 6.21 mm; canine, 8.55 mm; second premolar, 8.45 mm; and first molar, 10.02 mm. In the buccal side, the alveolar bone width was not increased from the crest to the apical region. The horizontal alveolar bone width of an apical and mandibular border region was thinner than at the mid-root level. Conclusions: The results of the preliminary study are useful as a clinical guideline when determining dental implant diameter and position. And also, these measurements can also be useful during the production of prefabricated membranes and customized alveolar bone scaffolds.

• 한국전자거래학회지
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• 제11권4호
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• pp.1-20
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• 2006

최근 전자정부 로드맵 과제 중 하나로 '범정부 정보기술아키텍처 적용'이 포함됨에 따라 여러 공공기관에서 EA 도입을 추진하고 있다. 그러나, EA 프레임워크, 표준, 원칙, 참조모델 등과 관련된 모델 정립 및 개발 기법 이제시되지 않아 각 기관 및 실무담당자의 어려움이 크다. 따라서 본 논문에서는 각국의 도입사례를 분석하여 공공기관 특성을 고려한 전자정부 EA도입을 위한 성과 및 변화관리 기반의 개발 방법을 제안한다. 전자정부 EA 도입을 위한 기법은 전자정부 EA구축이 다년도에 걸쳐 여러 기관의 협력에 의해 추진되어야 할 사업이므로 각 기관의 장기적 사업추진 과정을 전체 최적화 관점에서 객관적으로 모니터링 할 수 있는 EA 성과관리 모델과 EA에 대한 개념이 생소한 공공기관의 이해관계자들에게 EA에 대한 개념, EA가치와 필요성 등 전반적인 인지도 향상을 위한 계층별 변화관리 활동을 결합하고 있다. 동 기법의 활용은 행정자치부에서 수행한 EA 구축사례를 통하여 구체적으로 소개하였고, 이를 통하여 공공기관은 업무 프로세스 혁신 및 정보화 계획수립을 EA를 근간으로 보다 효과적으로 수행할 수 있다.

• 전자공학회논문지D
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• 제36D권10호
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• pp.51-60
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• 1999

본 논문에서는 홀로그래픽 메모리 시스템에서 효율적인 위상다중화를 위하여 기준빔으로 구현되는 네가지 형태의 위상코드를 생성시켰다. 프로그램적으로 $32 {\times} 32$의 동일한 픽셀수로 발생된 위상코드에 대하여 어드레스빔의 갯수를 계산하였고, 실제 광시스템에서 SLM의 비선형적 위상변조 특성을 고려하여 0%, 5%, 10% 15%, 20%, 25%의 에러율을 갖는 위상값을 의도적으로 부가하여 네 가지 형태의 위상코드들에 대한 각각 자기상관성분 및 상호상관성분을 시뮬레이션을 통해 계산함으로서 위상코드 간의 cross talk 및 신호대 잡음비를 비교, 분석하였다. 그 결과 $32 {\times} 32$의 픽셀수에 대해서는 의사랜덤 위상코드의 상호 상관에 의한 평균값이 0.067로 다른 형태의 랜덤위상코드들의 신호대 잡음비와 비교하여 가장 작게 나타났으며, 임의의 어드레스빔에 의한 순간적인 영상누화를 나타내는 표준편차값도 의사랜덤 위상코드가 0.0113으로 가장 작게 나타났다. 또한 픽셀수에 따른 영향을 분석하기 위해 $32 {\times} 32$, $64 {\times} 64$, $128 {\times} 128$, $256 {\times} 256$ 과 같이 어드레스의 빔 크기에 해당하는 픽셀수를 증가하여 같은 방법으로 시뮬레이션을 수행하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9101-9105
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• 2014

Background: The purpose of this study was to compare the accuracy and effectiveness of automated breast volume scanning (ABVS) and hand-held ultrasound (HHUS) in the detection of breast cancer in a large population group with a long-term follow-up, and to investigate whether different ultrasound systems may influence the estimation of cancer detection. Materials and Methods: Institutional review board approval was obtained for this retrospective study, and informed consent was waived. From September 2010 to August 2011, a total of 1,866 ABVS and 3,700 HHUS participants, who underwent these procedures at our institute, were included in this study. Cancers occurring during the study and subsequent follow-up were evaluated. The reference standard was a combination of histology and follow-up imaging (${\geq}12months$). The recall rate, cancer detection yield, diagnostic accuracy, sensitivity, specificity, and positive (PPV) and negative (NPV) predictive values were calculated with exact 95% confidence intervals. Results: The recall rate was 2.57 per 1,000 (48/1,866) for ABVS and 3.57 per 1,000 (132/3,700) for HHUS, with a significant difference (p=0.048). The cancer detection yield was 3.8 per 1,000 for ABVS and 2.7 per 1,000 for HHUS. The diagnostic accuracy was 97.7% for ABVS and 96.5% for HHUS with statistical significance (p=0.018). The specificity of ABVS and HHUS were 97.8%, 96.7%, respectively (p=0.022). Conclusions: ABVS shows a comparable diagnostic performance to HHUS. ABVS is an effective supplemental tool for mammography in breast cancer detection in a large population.

• 치위생과학회지
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• 제14권2호
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• pp.94-100
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• 2014

본 연구는 임상에서 널리 사용되고 있는 3종류의 탄성 인상재를 치과용 백색광 스캐너로 스캔하여 얻어진 데이터와 석고 지대치 모형과의 차이를 비교분석하였다. 인상재의 물성 차이가 3차원 디지털 모형의 정확성에 어떠한 영향을 미치는지 3차원 중첩 분석법을 통해 평가함으로써 다음과 같은 결과를 얻었다. 석고 지대치 모형과 3종류의 인상재를 토대로 채득된 디지털 모형의 차이를 비교한 결과, HB 그룹이 $9.80{\pm}1.52{\mu}m$ 로 가장 큰 차이를 보였으며, XLB 그룹이 $5.10{\pm}1.45{\mu}m$로 가장 작은 차이를 나타내었다. 음형의 인상체 간의 정확성에 있어서는 측정된 평균값이 통계적으로 유의한 차이를 보였다(p<0.05). Color difference map의 결과에서도 HB 그룹에 비해 XLB 그룹이 오차가 0에 가까운 연두색의 분포가 넓게 나타났기에, 더욱 안정적이며 정확한 디지털 모형 채득이 가능한 탄성 인상재라는 결론을 내릴 수 있다. 아직까지는 음형의 인상체 스캔방식은 표면의 혈흔이나 난반사, 중합 수축 등 좀 더 개선하고 보완해야 할 문제점들이 존재하기 때문에 널리 사용하진 않지만, 석고 모형과 비교하였을 때 전체적인 오차범위가 크지 않기에 임상적으로 허용될만한 수준으로 생각된다.

• 한국전자파학회논문지
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• 제28권5호
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• pp.382-390
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• 2017

본 논문에서는 저주파 대역 자기유도방식 상용 무선충전기기에 대해 특정 노출 조건을 고려하여 인체영향을 평가하였다. 상용 무선충전기기는 WPC(Wireless Power Consortium)에서 제안하는 Qi 규격 중 A10 모델을 대상으로 했으며, 155 kHz의 공진 주파수에서 5 W의 출력으로 동작한다. 송 수신기가 완벽히 정렬된 상태에서, 기기로부터 방사되는 누설 자기장은 기기의 측면에서 최대 $257.58{\mu}T$로 ICNIRP 2010 기준인 $27{\mu}T$보다 7.4배 초과하는 세기를 보였다. SAR(Specific Absorption Rate)는 젖은 피부의 전기적 상수를 적용한 균질 인체팬텀을 이용해 평가하였으며, 마찬가지로 기기의 측면에서 대략 $134.47{\mu}W/kg$으로 최댓값을 보였지만, 10 g 평균 SAR 국제 기준인 4 W/kg에 상당히 못 미치는 수준이었다. 오정렬 상태를 고려한 노출 조건에서 SAR는 대략 $199.43{\mu}W/kg$으로 일반적 노출 조건보다 대략 48 % 이상 증가했고, 이를 통해 무선전력전송 시스템의 인체영향을 평가할 때 오정렬 상태 또한 중요하게 고려할 필요가 있음을 확인하였다.

• 한국환경과학회지
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• 제14권2호
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• pp.221-230
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• 2005

Catalytic wet oxidation of trichloroethylene (TCE) in water has been conducted using $TiO_2-supported$ cobalt oxides at $36^{\circ}C$ with a weight hourly space velocity of $7,500\;h^{-1}.\;5\%\;CoO_x/TiO_2$, prepared by using an incipient wetness technique, might be the most promising catalyst for the wet oxidation although it exhibited a transient behavior in time on-stream activity. Not only could the bare support be inactive for the wet decomposition reaction, but no TCE removal also occurred by the process of adsorption on $TiO_2$ surface. The catalytic activity was independent of all particle sizes used, thereby representing no mass transfer limitation in intraparticle diffusion. XPS spectra of both fresh and used Co surfaces gave different surface spectral features for each $CoO_x,\;Co\;2P_{3/2}$ binding energy for Co species in the fresh catalyst appeared at 781.3 eV, which is very similar to the chemical states of $CoTiO_x$ such as $CO_2TiO_4\;and\;CoTiO_3$. The used catalyst exhibited a 780.3-eV main peak with a satellite structure at 795.8 eV. Based on XPS spectra of reference Co compound, the TCE-exposed Co surfaces could be assigned to be in the form of mainly $Co_3O_4$. XRD patterns for $5\%\;CoO_x/TiO_2$ catalyst indicated that the phase structure of Co species in the catalyst even before reaction is quite comparable to the diffraction lines of external $Co_3O_4$ standard. A model structure of $CoO_x$ present predominantly on titania surfaces would be $Co_3O_4$, encapsulated in thin-film $CoTiO_x$ species consisting of $Co_2TiO_4$ and $CoTiO_3$, which may be active for the decomposition of TCE in a flow of water.

• Journal of Radiation Protection and Research
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• 제20권1호
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• pp.25-36
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• 1995

The purpose of this research is to develop stereotactic localization and radiation measurement system for the efficient and precise radiosurgery. The algorithm to obtain a 3-D stereotactic coordinates of the target has been developed using a Fisher CT or angio localization. The procedure of stereotactic localization was programmed with PC computer, and consists of three steps: (1) transferring patient images into PC; (2) marking the position of target and reference points of the localizer from the patient image; (3) computing the stereotactic 3-D coordinates of target associated with position information of localizer. Coordinate transformation was quickly done on a real time base. The difference of coordinates computed from between Angio and CT localization method was within 2 mm, which could be generally accepted for the reliability of the localization system developed. We measured dose distribution in small fields of NEC 6 MVX linear accelerator using various detector; ion chamber, film, diode. Specific quantities measured include output factor, percent depth dose (PDD), tissue maximum ratio (TMR), off-axis ratio (OAR). There was small variation of measured data according to the different kinds of detectors used. The overall trends of measured beam data were similar enough to rely on our measurement. The measurement was performed with the use of hand-made spherical water phantom and film for standard arc set-up. We obtained the dose distribution as we expected. In conclusion, PC-based 3-D stereotactic localization system was developed to determine the stereotactic coordinate of the target. A convenient technique for the small field measurement was demonstrated. Those methods will be much helpful for the stereotactic radiosurgery.