• 제목/요약/키워드: reduction synthesis

Search Result 1,067, Processing Time 0.037 seconds

Effect of Silk Fibroin Hydrolysate on Adipocyte Metabolism in db/db Mice (실크 피브로인 산 가수분해물이 db/db mice의 지방세포 대사에 미치는 영향)

  • Hong, Seong-Eui;Park, Kum-Ju;Suh, Byung-Sun;Do, Myoung-Sool;Hyun, Chang-Kee
    • Korean Journal of Pharmacognosy
    • /
    • v.33 no.4 s.131
    • /
    • pp.312-318
    • /
    • 2002
  • Effect of the acid hydrolysate of silk fibroin on obesity was investigated in obese(057BL/KsJ-db/db) mice. After 8 weeks feeding of 1%(w/w) or 3%(w/w) fibroin hydrolysate, the extents of reduction in body weight were significantly higher than that of obese control. The weight reduction in female mice was higher than that in male mice. Plasma leptin in male mice increased up to 1.8-fold higher level than obese control by feeding hydrolysate. In case of female mice, however, it rather decreased with increased feeding concentration of hydrolysate. From the results of high glycine and serine contents of peptide fractions contained in fibroin hydrolysate, it was inferred that fibroin peptides might affect xylosyltransferase(XT) activity on chondroitin sulfate synthesis causing to change susceptibility of adipocytes to hormones such as insulin followed by the reduced leptin synthesis in female mice. The result of the higher lipolysis in hydrolysate-fed group than obese control indicated that the reduction in body weight was due to the increased lipolytic activities in male and female mice in common.

Synthesis of Bi-Sb-Te-based Thermoelectric Powder by an Oxide-reduction Process (산화물 환원공정에 의한 Bi-Sb-Te계 열전분말 합성)

  • Lee, Gil-Geun;Kim, Sung-Hyun;Ha, Gook-Hyun;Kim, Kyung-Tae
    • Journal of Powder Materials
    • /
    • v.17 no.4
    • /
    • pp.336-341
    • /
    • 2010
  • The present study focused on the synthesis of Bi-Sb-Te-based thermoelectric powder by an oxidereduction process. The phase structure, particle size of the synthesized powders were analyzed using XRD and SEM. The synthesized powder was sintered by the spark plasma sintering method. The thermoelectric property of the sintered body was evaluated by measuring the Seebeck coefficient and specific electric resistivity. The $Bi_{0.5}Sb_{1.5}Te_3$ powder had been synthesized by a combination of mechanical milling, calcination and reduction processes using mixture of $Bi_2O_3$, $Sb_2O_3$ and $TeO_2$ powders. The sintered body of the $Bi_{0.5}Sb_{1.5}Te_3$ powder synthesized by an oxide-reduction process showed p-type thermoelectric characteristics, even though it had lower thermoelectric properties than the sintered body of the $Bi_{0.5}Sb_{1.5}Te_3$ thermoelectric powder synthesized by the conventional melting-crushing method.

A Study on the Vibration Characteristics of Weaving Machine Structure using Component Mode Synthesis (부분구조합성법을 이용한 제직기 구조물의 진도특성에 관한 연구)

  • 권상석;김병옥;전두환
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2001.05a
    • /
    • pp.535-539
    • /
    • 2001
  • In these days. the finite element method(FEM) is a very common method for not only a simple vibration analysis but also the optimization of structures. Since the finite element model may contain thousands of degree of freedom, the eigensolutions require extreme computing power, which will result in a serious time-consuming problem. Thus, many researchers have challenged to find more improved modeling techniques and calculating methods to overcome such problems. The Guyan reduction method and the substructure synthesis method are typical examples of such methods. Of the substructure synthesis method, the component mode synthesis method (CMS) is widely used for dynamic analysis of structure. In this study. for the efficient analysis of jet loom structure. Component Mode Synthesis was carried out. The results of the finite element program developed are compared with those of the commercial package program ANSYS for the validation of the program. The results obtained by the program showed a good agreement with those of ANSYS. The program will be further refined and verified by test to yield more accurate results.

  • PDF

Synthesis of Dopamine by Plasma (플라즈마를 이용한 도파민 합성)

  • Kim, Seong-In;Lee, Deok-Yeon;Lee, Hae-Sin
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2014.02a
    • /
    • pp.121.2-121.2
    • /
    • 2014
  • Synthesis of catecholamine from aniline is achieved by plasma enhanced CVD process. Catecholamine has a variety of functions in body such as brain and bloodstream controls. Catecholamine also has an interesting property of a material independent ability of functionalizing surface, which is found at mussels' adhesive nature. Synthesis of catecholamine has only been available from DOPA by chemical reduction and oxidation. This study presents the direct synthesis of catecholamine from further elemental source, aniline, which has not been achieved by a conventional chemical method. The process also indicates that a variety of catecholamine can be formed by controlling reactant gases. In additional to PECVD's very useful properties such as conformal, ultrathin and uniform coatings, a direct synthesis from aniline and a capability of controlling formation of a variety catecholamine is believed to open up a numerous applications.

  • PDF

A Study of Mode of Action of Alachlor - I. Effects of Alachlor on Nucleic acid, Amino acid and Protein Synthesis in Oat(Avena sativa L.) (Alachlor의 제초기구(除草機構)에 관한 연구(硏究) - I.Alachlor가 귀리의 핵산(核酸), 아미노산 및 단백질합성(蛋白質合成)에 미치는 영향(影響))

  • Kwon, S.W.;Kim, J.C.
    • Korean Journal of Weed Science
    • /
    • v.10 no.3
    • /
    • pp.227-232
    • /
    • 1990
  • The effects of alachlor [2-chloro-2', 6' diethyl-N-(methoxymethyl) acetanilide] treatment on nucleic acid, amino acid and protein synthesis were studied. The amide herbicide alachlor blocks the biosynthesis of the amino acids isoleucine, valine and aromatic amino acid in oat root tips. Nucleic acid was inhibited, but was not proportional to reduction in protein synthesis. $1{\times}10^{-4}M$ of alachlor treatment of oat roots inhibited 36% DNA synthesis, but DNA synthesis was not inhibited at $1{\times}10^{-5}M$. RNA synthesis was inhibited by $1{\times}10^{-5}M$ and $1{\times}10^{-4}M$ of alachlor 16 and 27%, respectively, while inhibition of protein synthesis did occur at same concentrations. Inhibition of protein synthesis also did not occur at concentration below $1{\times}10^{-4}M$ alachlor. It suggest that inhibition of protein sythesis caused significantly by alachlor($1{\times}l0^{-3}M$) result from secondary action.

  • PDF

STUDY ON THE OPTIMAL PLANAR ARRAY STRUCTURE WITH TRIANGULAR LATTICE FOR SIDE-LOBE REDUCTION (삼각 격자구조를 갖는 평면배열 안테나의 부엽 레벨 감소를 위한 최적 평면배열 형상에 관한 연구)

  • 배지훈;성낙선;이태윤;김종면;표철식
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
    • /
    • 2002.11a
    • /
    • pp.250-254
    • /
    • 2002
  • In this paper, we design an optimized planar array structure with triangular lattice for side-lobe reduction using a genetic algorithm. A constraint optimization is implemented by optimally removing some outer array elements far from the array center. It is shown that only the proper array shape without optimizing the magnitudes and phases of each array antenna can give low side-lobe level with a slight main beam broadening.

  • PDF

Synthesis of metallic copper nanoparticles and metal-metal bonding process using them

  • Kobayashi, Yoshio;Nakazawa, Hiroaki;Maeda, Takafumi;Yasuda, Yusuke;Morita, Toshiaki
    • Advances in nano research
    • /
    • v.5 no.4
    • /
    • pp.359-372
    • /
    • 2017
  • Metallic copper nanoparticles were synthesised by reduction of copper ions in aqueous solution, and metal-metal bonding by using the nanoparticles was studied. A colloid solution of metallic copper nanoparticles was prepared by mixing an aqueous solution of $CuCl_2$ (0.01 M) and an aqueous solution of hydrazine (reductant) (0.2-1.0 M) in the presence of 0.0005 M of citric acid and 0.005 M of n-hexadecyltrimethylammonium bromide (stabilizers) at reduction temperature of $30-80^{\circ}C$. Copper-particle size varied (in the range of ca. 80-165 nm) with varying hydrazine concentration and reduction temperature. These dependences of particle size are explained by changes in number of metallic-copper-particle nuclei (determined by reduction rate) and changes in collision frequency of particles (based on movement of particles in accordance with temperature). The main component in the nanoparticles is metallic copper, and the metallic-copper particles are polycrystalline. Metallic-copper discs were successfully bonded by annealing at $400^{\circ}C$ and pressure of 1.2 MPa for 5 min in hydrogen gas with the help of the metalli-ccopper particles. Shear strength of the bonded copper discs was then measured. Dependences of shear strength on hydrazine concentration and reduction temperature were explained in terms of progress state of reduction, amount of impurity and particle size. Highest shear strength of 40.0 MPa was recorded for a colloid solution prepared at hydrazine concentration of 0.8 M and reduction temperature of $50^{\circ}C$.

pH-Controlled Synthesis of Cephalexin by a Purified Acetobacter turbidans Ampicillin Acylase

  • Nam, Doo-Hyun;Ryu, Yeon-Woo;Dewey D.Y Ryu
    • Journal of Microbiology and Biotechnology
    • /
    • v.11 no.2
    • /
    • pp.329-332
    • /
    • 2001
  • It has been known that, in enzymatic synthesis of cephalexin, the conversion yield was reduced by high loading of ampicillin acylase. In order to elucidate this phenomena, pH-controlled synthesis of cephalexin was examined using a purified Acetobacter turbidans acylase. When the pH of the reaction mixture was maintained at $6.20{\pm}0.04$, the reduction of the maximal conversion rate was not observed even with high enzyme loading. The kinetic parameters also suggest that pH drop during the enzymatic synthesis of cephalexin was mainly attributed to the rapid hydrolysis of D-${\alpha}$-phenylglycine methyl ester to D-${\alpha}$-phenylglycine, rather than the disappearance of 7-amino-3-deacetoxycephalosporanic acid for cephalexin synthesis. At higher molar ratio of two substrates, [D-${\alpha}$-phenylglycine methyl ester]/[7-amino-3-deacetoxycephalosporanic acid], the conversion rate was also elevated under pH-controlled enzymatic synthesis, which implies that the main reason for the pH drop is due to the production of D-${\alpha}$-phenylglycine methyl easter, the effect of a water-methanol cosolvent system on the ester, the effect of a water-methanol cosolvent system on the conversion profile was also examined. Even the though the conversion rate was increased in 10% methanol solution, a higher than 16% methanol in the reaction mixture caused an inactivation of enzyme.

  • PDF