• 제목/요약/키워드: reduced sample size

검색결과 154건 처리시간 0.034초

Acupotomy for Osteoarthritis of the Knee; A Systematic Review and Meta-Analysis

  • Lee, Seung Min;Lee, Cham Kyul;Kim, Kyung Ho;Kim, Eun Jung;Jung, Chan Yung;Seo, Byung-Kwan;Goo, Bon Hyuk;Baek, Yong Hyeon;Lee, Eun Yong
    • Journal of Acupuncture Research
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    • 제38권2호
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    • pp.96-109
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    • 2021
  • The purpose of this study was to evaluate the effectiveness and safety of acupotomy for the treatment of patients with knee osteoarthritis. There were 9 databases searched to retrieve randomized controlled trials until August 3, 2019 regarding acupotomy versus conventional Western medicine, conventional Western medicine treatment with and without acupotomy, and Korean medicine treatment with and without acupotomy, and meta-analysis was performed. Of 303 potentially relevant studies retrieved, 43 were systematically reviewed. All studies were conducted in China. Effective rate, visual analogue scale, and Western Ontario and McMaster Universities Osteoarthritis index were used as the evaluation scales. The Ashi point was selected most frequently. In all studies, the intervention group was more effective than the control group. Meta-analysis revealed that acupotomy showed statistically significant beneficial results. Although acupotomy had a beneficial effect on knee osteoarthritis, the risk of bias of the included studies was not low. The majority of the results from the evaluation scales used were highly heterogeneous (> 50%) which reduced confidence in the estimation of effect, or had a small sample size. Further clinical research and development is required in the future.

Al-Ni 전구체의 연소합성 발포에 의한 Al3Ni 폼과 할로우 파이프의 복합구조체 제작 및 폼의 충진성과 기공상태 조사 (Combustion of Al-Ni Precursor Al3Ni Foam Manufacture of Composite Structure with Hollow Pipe and Filling of Foam and Investigation of Pore Condition)

  • 한창석;진성윤;권혁구
    • 한국재료학회지
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    • 제29권10호
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    • pp.617-622
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    • 2019
  • In order to develop a process for manufacturing a composite structure of an intermetallic compound foam and a hollow material, the firing and pore form of the Al-Ni precursor in a steel pipe are investigated. When the Al-Ni precursor is foamed in a hollow pipe, if the temperature distribution inside the precursor is uneven, the pore shape distribution becomes uneven. In free foaming, no anisotropy is observed in the foaming direction and the pore shape is isotropic. However, in the hollow pipe, the pipe expands in the pipe axis direction and fills the pipe. The interfacial adhesion between $Al_3Ni$ foam and steel pipe is excellent, and interfacial pore and reaction layer are not observed by SEM. In free foaming, the porosity is 90 %, but it decreases to about 80 % in the foam in the pipe. In the pipe foaming, most of the pore shape appears elongated in the pipe direction in the vicinity of the pipe, and this tendency is more remarkable when the inside pipe diameter is small. It can be seen that the pore size of the foam sample in the pipe is larger than that of free foam, because coarse pores remain after solidification of the foam because the shape of the foam is supported by the pipe. The vertical/horizontal length ratio expands along the pipe axis direction by foaming in the pipe, and therefore circularity is reduced.

Regional Differences in the Effects of Social Relations on Depression Among Korean Elderly and the Moderating Effect of Living Alone

  • Kim, Chanki;Chang, Eun Jee;Kim, Chang-yup
    • Journal of Preventive Medicine and Public Health
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    • 제54권6호
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    • pp.441-450
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    • 2021
  • Objectives: Socioeconomic disadvantages interact with numerous factors which affect geriatric mental health. One of the main factors is the social relations of the elderly. The elderly have different experiences and meanings in their social lives depending on their socio-cultural environment. In this study, we compared the effects of social relations on depression among the elderly according to their living arrangement (living alone or living with others) and residential area. Methods: We defined social relations as "meetings with neighbors" (MN). We then analyzed the impact of MN on depression using data from the Korean Longitudinal Study of Aging Panel with the generalized estimating equation model. We also examined the moderating effect of living alone and performed subgroup analysis by dividing the sample according to which area they lived in. Results: MN was associated with a reduced risk of depressive symptoms among elderlies. The size of the effect was larger in rural areas than in large cities. However, elderly those who lived alone in rural areas had a smaller protective impact of MN on depression, comparing to those who lived with others. The moderating effect of living alone was significant only in rural areas. Conclusions: The social relations among elderlies had a positive effect on their mental health: The more frequent MN were held, the less risk of depressive symptoms occurred. However, the effect may vary depending on their living arrangement and environment. Thus, policies or programs targeting to enhance geriatric mental health should consider different socio-cultural backgrounds among elderlies.

Effectiveness of Acupuncture and Acupotomy for Trigger Finger: A Systematic Review and Meta-Analysis

  • Hae-Won Hong;Myung-In Jeong;Hyun-Il Jo;Sun-Ho Lee;Ka-Hyun Kim;Sung-Won Choi;Jae-Won Park;Ji-Su Ha
    • Journal of Acupuncture Research
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    • 제40권2호
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    • pp.111-128
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    • 2023
  • Trigger finger is a common cause of hand disability that results in finger catching, clicking, or locking. Conventional treatment options such as medication, injection, and surgery have limitations. Studies have indicated that acupuncture and acupotomy can be effective in treating trigger finger. However, no review regarding these treatment modalities has been published yet. This review included randomized controlled trials published until January 2023, investigating acupuncture-related interventions. The primary outcomes of interest included the effectiveness rate (ER) and pain intensity, measured using a visual analog scale (VAS) and Numerical Rating Scale (NRS), and secondary outcomes were the Quinnell grade (QG) and recurrence rate (RR). Adverse events (AEs) have also been reported wherever available. Overall, 19 studies were included, and results demonstrated that arcedge acupuncture improved the ER and QG and reduced NRS, and acupuncture was effective in reducing VAS. Compared with conventional surgery, acupotomy alone improved the ER and QG and lowered VAS and RR, with relatively fewer AEs. Acupotomy add-on treatment was more effective than conventional treatment; however, careful interpretation is needed for VAS. Acupotomy add-on treatment was more effective than acupotomy alone. However, the overall results must be interpreted with caution because of study quality, small sample size, and heterogeneity of the results.

Continuous W-Cu functional gradient material from pure W to W-Cu layer prepared by a modified sedimentation method

  • Bangzheng Wei;Rui Zhou;Dang Xu;Ruizhi Chen;Xinxi Yu;Pengqi Chen;Jigui Cheng
    • Nuclear Engineering and Technology
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    • 제54권12호
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    • pp.4491-4498
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    • 2022
  • The thermal stress between W plasma-facing material (PFM) and Cu heat sink in fusion reactors can be significantly reduced by using a W-Cu functionally graded material (W-Cu FGM) interlayer. However, there is still considerable stress at the joining interface between W and W-Cu FGM in the W/W-Cu FGM/Cu portions. In this work, we fabricate W skeletons with continuous gradients in porosity by a modified sedimentation method. Sintering densification behavior and pore characteristics of the sedimented W skeletons at different sintering temperatures were investigated. After Cu infiltration, the final W-Cu FGM was obtained. The results indicate that the pore size and porosity in the W skeleton decrease gradually with the increase of sintering temperature, but the increase of skeleton sintering temperature does not reduce the gradient range of composition distribution of the final prepared W-Cu FGM. And W-Cu FGM with composition distribution from pure W to W-20.5wt.% Cu layer across the section was successfully obtained. The thickness of the pure W layer is about one-fifth of the whole sample thickness. In addition, the prepared W-Cu FGM has a relative density of 94.5 % and thermal conductivity of 185 W/(m·K). The W-Cu FGM prepared in this work may provide a good solution to alleviate the thermal stress between W PFM and Cu heat sink in the fusion reactors.

Clinical and patient-reported outcomes after recession coverage using modified vestibular incision subperiosteal tunnel access with a volume-stable collagen matrix as compared to a coronally advanced flap with a subepithelial connective tissue graft

  • Chun-Teh Lee;Marlena Lange;Alain Jureidini;Nurit Bittner;Ulrike Schulze-Spate
    • Journal of Periodontal and Implant Science
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    • 제52권6호
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    • pp.466-478
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    • 2022
  • Purpose: Coronally advanced split-or full-thickness (CAST or CAFT) flaps in combination with subepithelial connective tissue grafts (SCTGs) are commonly used in root-coverage procedures despite postoperative pain and bleeding from the graft donor site. Therefore, the modified vestibular incision subperiosteal tunnel access procedure (VISTAX) uses a novel collagen matrix (VCMX) instead of autogenous tissue to address the limitations associated with autogenous tissue grafting. This retrospective study compared the clinical outcomes of VISTAX to the results obtained after using a CAST or CAFT flap in combination with SCTG for root coverage. Methods: Patients with single or multiple adjacent recession I/II defects were included, with 10 subjects each in the VISTAX, CAFT, and CAST groups. Defect coverage, keratinized tissue width, esthetic scores, and patients' perceived pain and dentinal hypersensitivity (visual analogue scale [VAS]) were assessed at baseline, 3 months, and 6 months. Results: All surgical techniques significantly reduced gingival recession (P<0.0001). Defect coverage, esthetic appearance, and the reduction in dentinal hypersensitivity were comparable. However, the VAS scores for pain were significantly lower in the VISTAX group than in the CAFT and CAST groups, which had similar scores (P<0.05). Furthermore, the clinical results of VISTAX and CAFT/CAST generally remained stable at 6 months. Conclusions: The clinical outcomes of VISTAX, CAFT, and CAST were comparable. However, patients perceived significantly less pain after VISTAX, indicating a potentially higher patient acceptance of the procedure. A prospective trial with a longer follow-up period and a larger sample size should therefore evaluate VISTAX further.

라만 및 FT-IR 현미경을 이용한 천일염 중 미세플라스틱 분석 (Identification of Microplastics in Sea Salts by Raman Microscopy and FT-IR Microscopy)

  • Cho, Soo-Ah;Cho, Won-Bo;Kim, Su-Bin;Chung, Jae-Hak;Kim, Hyo-Jin
    • 분석과학
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    • 제32권6호
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    • pp.243-251
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    • 2019
  • 미세플라스틱이 해양에서 대량으로 발견되어 생태계에 큰 위협이 되고 있다. 국내에서도 우리가 실생활에서 직접 섭취하거나 음식에 많이 사용되는 천일염에서 미세플라스틱이 검출되었다는 보고가 있었다. 미세플라스틱을 분석하기 위하여는 성분, 크기, 모양 등에 대한 정보가 필요하며 이를 위하여 20 ㎛ 크기까지는 FT-IR 현미경이 가장 많이 사용되고 있다. 그러나 최근에는 20 ㎛ 이하의 초 미세 플라스틱 분석이 가능한 라만 현미경법이 함께 많이 연구되고 있다. 본 연구에서는 시판 천일염 10.0 g을 녹인 후 25.4 mm × 25.4 mm 크기의 45 ㎛ mesh 필터로 여과한 후 필터 시료를 각각 FT-IR 현미경과 라만 현미경을 사용하여 미세플라스틱을 분석하였다. FT-IR 현미경의 경우 70 ㎛에서 100 ㎛까지의 3개의 폴리에틸렌(PE)와 170 ㎛의 폴리프로필렌(PP)가 검출되었다. 라만현미경에서는 45 ㎛ 필터를 사용하였음에도 불구하고 필터의 일부에 걸쳐서 여과되지 않고 존재하던 10 ㎛, 30 ㎛의 PE를 포함하여 50 ㎛에서 120 ㎛까지 총 9 개의 PE와 1 개의 40 ㎛ 크기의 폴리스티렌(PS) 1 개가 검출되었다. 검출된 PE 중에는 PE와 Al2O3가 함께 결합한 70 ㎛ 미세플라스틱과 원형이 아닌 200 ㎛ × 30 ㎛, 150 ㎛ × 20 ㎛의 비정형 PE도 함께 측정되었다. 미세플라스틱 외에도 총 100 개 이상의 입자들이 측정되었으며 이들의 조성을 보면 5 개의 셀룰로오스, 16 개의 유리류, 35 개의 탄소, 28 개의 미네랄등과 확인이 되지 못한 19 개의 입자들이 측정되었다. 따라서 라만현미경은 적외선현미경에 비하여 20 ㎛ 이하의 미세플라스틱도 측정이 가능하기 때문에 시료의 량도 10배이상 적게 사용할 수 있어 시료 전처리 및 크기에 따른 분석오차를 줄일 수 있다.

자조집단 프로그램이 유방절제술 환자의 적응과 삶의 질에 미치는 효과 (The Effect of Self-help Group Program on Adaptation and Quality of Life of Mastectomy Patients)

  • 박영신;임난영
    • 재활간호학회지
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    • 제2권1호
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    • pp.61-71
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    • 1999
  • This quasi-experimental study was intended to test the effect of self-help group program, which is one of the way to enhance adaptation and quality of life to mastectomy patients. Data was collected from July 14, 1998 to Oct. 31, 1998 at two Medical Center in Seoul. The subjects for this study were the patients who had undergone mastectomy and were follow-up ; 14 in experimental group and 14 in control group matched with age and treatment. The instruments for this study were adaptation in Lee(1994)'s physical symptom questionnaire, Zung's Self-rating Depression Scale(SDS, 1965), and Self-rating Anxiety Scale(SAS, 1970), quality of life in Spranger(1996)'s and No(1988)'s Quality of Life Questionnaire. The self-help group program for mastectomy patients was developed based on literature review and pilot study by the investigator. The subjects of experimental group were participated in 6 weeks self-help group program and were received arm and shoulder exercise, informational support, and interpersonal support by group members. The control group were received no intervention, Both group answered questionnaires prior to intervention and 6 weeks later. The data analyzed by frequency, $X^2$-test, Mann-Whitney U test. Wilcoxon Signed Rank test, Pearson's Correlation Coefficient and Stepwise Multiple Regression using SPSS WIN. The results are as follows ; Hypothesis 1. "The experimental group with the self-help group program will have a higher score on adaptation state than control group." was not supported. But the post test score of anxiety and depression in experimental group were declined and the depression score was reduced relatively. Hypothesis 2. "The experimental group with the self-help group program will have a higher score on quality of life than control group." was not supported. But the posttest score of quality of life in experimental group was reduced relatively. Hypothesis 3. "The higher adaptation state of mastectomy patients, the higher quality, of life." was supported(r=,80, p<.001). Additionally, the lower physical symptom, depression and anxiety, the higher quality of life And depression, which was the main predictor of quality of life, accounted for 59.5%, depression and anxiety accounted for 65.5% of the variance in quality of life. In conclusion, when the self-help group program was intervened to mastectomy patients, it was tended to increase quality of life and to reduce depression and anxiety. So self-help group program can be considered useful nursing inter vention effect on adaptation and quality of life of mastectomy patients. With discussion, I suggest repeated further re search on self-help group with appropriate sample size and longitudinal study. Also during adjuvant therapy, it is needed to develop convenient method to be supported from peer group and family, such as computer mediated support group.

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DEA를 이용한 전복종자 생산업체의 경영효율성 분석 (Analysis of Management Efficiency for Abalone Seed Producer based on DEA Approach)

  • 오예진;이남수;김대영
    • 수산경영론집
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    • 제51권1호
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    • pp.37-52
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    • 2020
  • The production of abalone seed has grown and been specialized since the 2000s with the growth of the abalone farming industry. Despite the increase in the production of abalone seeds, the sales volume of abalone seeds remained flat and competition among producers increased. This paper will analyze the management efficiency of abalone seed production fishery to diagnose the management status and improve the abalone seed production efficiency. In addition, this study is the result of the basic research on the abalone seed industry and it is meaningful to prepare a platform for further research since the management status survey and the management efficiency survey of abalone seed production fishery have not been conducted until now. The data on the farmed fish prices of abalone seeds were collected from surveys of sample fish as part of the fish seed observation project conducted by the Fisheries Outlook Center (FOC) of Korea Maritime and Fisheries Development Institute (KMI). Management efficiency analysis utilizes DEA (Data Envelopment Analysis) model. The DEA model was analyzed by classifying into CCR (Super-CCR), BCC, and SBM (Super-SBM) models according to the assumptions taking into account the characteristics of the industry. The slack considered in the SBM model was judged as possible decreases in input variables and increase in output variables. The average efficiency from the CCR model was analyzed to be 69%. The BCC model was classified into input and output orientations, and the average efficiency was 79% and 75%, respectively. There were seven production fisheries with an SE value of 1 or more, which remained unchanged in terms of size and could be benchmarked. The average efficiency of the SBM model was 59% for CRS and 66% for VRS. Under the VRS assumptions, the variable increase/decrease efficiency analysis shows that labor costs can be reduced by 37.3%, facility capacity by 18.8%, and operating costs by 8.5%. In order to improve management efficiency, Wando needs to reduce labor and management costs. In Jindo region, sales increase as well as labor cost reduction is urgent. In other regions, reduced facilities and increased sales are recommended.

이온교환법에 의한 환원 그래핀-금속 하이브리드 소재의 합성 및 특성 (Synthesis of Reduced Graphene-metal Hybrid Materials via Ion-exchange Method and its Characterization)

  • 박애리;김수민;김현;한종훈
    • 마이크로전자및패키징학회지
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    • 제27권4호
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    • pp.25-37
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    • 2020
  • 본 연구에서는 그래핀 소재의 전기전도성 및 자기적 특성을 향상시키기 위해 산화그래핀 표면상의 산소를 포함한 기능기와 열처리 환원공정을 이용하여 환원그래핀과 금속소재를 하리브리드화 하였다. 산화 그래핀 표면의 -OH, -COOH 등의 산소 포함 기능기들을 열처리 환원시킴과 동시에 금속이온을 기능기와의 이온교환법에 의해 치환 합성하는 연구를 진행하였다. 하이브리드 소재 합성에 사용된 금속은 Fe, Ag, Ni, Zn, Fe/Ag이며 SEM, TEM 및 EDS를 통해 환원 그래핀 표면 위에 균일한 크기의 금속 입자가 비교적 구형 잘 분산되었음을 확인하였다. 그래핀 표면상의 금속입자들은 모두 산화물 형태의 구조를 가지고 있었다. 하이브리드 소재의 전기적 특성을 확인하기 위해 rGO-metal hybrid 시료를 PET film에 dip-coating 방법으로 후막 필름을 형성시킨 후 면저항을 측정하였고, SEM을 통해 시편의 두께를 측정하여 비저항을 계산한 결과, 비저항의 범위는 2.14×10-5 ~ 3.5×10-3 ohm/cm범위에 있음을 확인하였다.