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Fabrication and Characterization of Taraxacum platycarpum Extract-loaded Particles for Tablet Dosage Form (정제 제형 제조를 위한 포공영 추출물 함유 분말의 제조 및 평가)

  • Jin, Sung Giu
    • Journal of Powder Materials
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    • v.26 no.3
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    • pp.225-230
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    • 2019
  • To develop Taraxacum platycarpum extract (TP)-loaded particles for tablet dosage form, various TP-loaded particles composed of TP, dextrin, microcrystalline cellulose (MCC), silicon dioxide, ethanol, and water are prepared using a spray-drying method and fluid-bed-drying method. Their physical properties are evaluated using angle of repose, Hausner ratio, Carr's index, hardness, disintegrant time, and scanning electron microscopy. Optimal TP-loaded particles improve flowability and compressibility. Furthermore, 2% silicon dioxide gives increased flowability and compressibility. The formula of TP-loaded fluid-bed-drying particles at a TP/MCC/silicon-dioxide amount of 5/5/0.2 improves the angle of repose, Hausner ratio, Carr's index, hardness, and disintegrant time as compared with the TP-loaded spray-drying particles. The TP-loaded fluid-bed-drying particles considerably improve flowability and compressibility ($35.10^{\circ}$ vs. $40.3^{\circ}$, 0.97 vs. 1.17, and 18.97% vs. 28.97% for the angle of repose, Hausner ratio, and Carr's index, respectively), hardness (11.34 vs. 4.7 KP), and disintegrant time (7.4 vs. 10.4 min) as compared with the TP-loaded spray-drying particles. Thus, the results suggest that these fluid-bed-drying particles with MCC and silicon dioxide can be used as powerful particles to improve the flowability and compressibility of the TP.

A Pattern Matching Extended Compression Algorithm for DNA Sequences

  • Murugan., A;Punitha., K
    • International Journal of Computer Science & Network Security
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    • v.21 no.8
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    • pp.196-202
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    • 2021
  • DNA sequencing provides fundamental data in genomics, bioinformatics, biology and many other research areas. With the emergent evolution in DNA sequencing technology, a massive amount of genomic data is produced every day, mainly DNA sequences, craving for more storage and bandwidth. Unfortunately, managing, analyzing and specifically storing these large amounts of data become a major scientific challenge for bioinformatics. Those large volumes of data also require a fast transmission, effective storage, superior functionality and provision of quick access to any record. Data storage costs have a considerable proportion of total cost in the formation and analysis of DNA sequences. In particular, there is a need of highly control of disk storage capacity of DNA sequences but the standard compression techniques unsuccessful to compress these sequences. Several specialized techniques were introduced for this purpose. Therefore, to overcome all these above challenges, lossless compression techniques have become necessary. In this paper, it is described a new DNA compression mechanism of pattern matching extended Compression algorithm that read the input sequence as segments and find the matching pattern and store it in a permanent or temporary table based on number of bases. The remaining unmatched sequence is been converted into the binary form and then it is been grouped into binary bits i.e. of seven bits and gain these bits are been converted into an ASCII form. Finally, the proposed algorithm dynamically calculates the compression ratio. Thus the results show that pattern matching extended Compression algorithm outperforms cutting-edge compressors and proves its efficiency in terms of compression ratio regardless of the file size of the data.

A Study on the Present Conditions, Exterior View, and Elevation Form of Housing in Munhwa-Maul (문화(文化)마을의 현황(現況)과 주택외관(住宅外觀) 및 입면형태(立面形態)에 관(關)한 연구(硏究))

  • Chong, Geon-Chai
    • Journal of the Korean Institute of Rural Architecture
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    • v.7 no.1
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    • pp.1-10
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    • 2005
  • The aim of This study is to establish existing of Munhwa-Maul, and analysis exterior form and elevation types of housing in new village of rural area. And it was studied on data and general conditions about it. The analysis of this research is divided into main categories as follow; classification of exterior form types, drawing an elevation of housing in Munhwa-Maul. So, I needed both field survey and research for data of 22 new village. Through this study and the results of survey are as follows; Munhwa-Maul is role to establish people settled village in rural area. The types of house are several and various in Munhwa-Maul. Especially, masonry construction type of housing has about 80%. But recently new types of housing are on the increase. So, Munhwa-Maul has a new landscape of village. It was grouped by three exterior form of dwelling housing. The ratio of box form has about 40%. Lastly, the types of elevation are four. Flat-roof style has about 70% including eyebrow flat-roof.

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Flapwise and non-local bending vibration of the rotating beams

  • Mohammadnejad, Mehrdad;Saffari, Hamed
    • Structural Engineering and Mechanics
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    • v.72 no.2
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    • pp.229-244
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    • 2019
  • Weak form integral equations are developed to investigate the flapwise bending vibration of the rotating beams. Rayleigh and Eringen nonlocal elasticity theories are used to investigate the rotatory inertia and Size-dependency effects on the flapwise bending vibration of the rotating cantilever beams, respectively. Through repetitive integrations, the governing partial differential equations are converted into weak form integral equations. The novelty of the presented approach is the approximation of the mode shape function by a power series which converts the equations into solvable one. Substitution of the power series into weak form integral equations results in a system of linear algebraic equations. The natural frequencies are determined by calculation of the non-trivial solution for resulting system of equations. Accuracy of the proposed method is verified through several numerical examples, in which the influence of the geometry properties, rotatory inertia, rotational speed, taper ratio and size-dependency are investigated on the natural frequencies of the rotating beam. Application of the weak form integral equations has made the solution simpler and shorter in the mathematical process. Presented relations can be used to obtain a close-form solution for quick calculation of the first five natural frequencies of the beams with flapwise vibration and non-local effects. The analysis results are compared with those obtained from other available published references.

Closed Form Expression for Signal Transmission via AF Relaying over Nakagami-m Fading Channels

  • Mughal, Muhammad Ozair;Kim, Sun-Woo
    • Proceedings of the IEEK Conference
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    • 2008.06a
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    • pp.213-214
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    • 2008
  • In this paper, we analyze the performance of a cooperative communication wireless network over independent and identically distributed (IID) Nakagami-m fading channels. A simple transmission scheme is considered where the relay is operating in amplify-forward (AF) mode. A closed-form expression for symbol error rate (SER) is obtained using the moment generating function (MGF) of the total signal to noise ratio (SNR) of the transmitted signal with binary phase shift keying (BPSK).

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A Large Trans/cis Conversion Ratio In Redox-Conjugated Single-Light Reversible Isomerization of a Cobalt Complex with meta-Bipyridylazobenzene Ligands

  • Kume, Shoko;Kurihara, Masato;Nishihara, Hiroshi
    • Journal of the Korean Electrochemical Society
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    • v.5 no.4
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    • pp.189-191
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    • 2002
  • Reversible trans-cis isomerization of meta-bipyridylazobenzene coordinated to cobalt was achieved by a combination of photoirradiation with a single UV light source and a Co(II)/Co(III) redox reaction. The trans/cis conversion performance was significantly improved in the meta-form compared with the meta-form ligated to cobalt.

Numerical Simulation on Equivalence Ratio Fluctuation at the Fuel Injection Hole with respect to Pressure Fluctuation in a Combustion Chamber (연소실내의 압력 변동에 따른 연료 분사구에서의 당량비 변동에 관한 수치해석)

  • Kim, Hyeon-Jun;Hong, Jung-Goo;Shin, Hyun-Dong
    • 한국연소학회:학술대회논문집
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    • 2006.10a
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    • pp.27-35
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    • 2006
  • It has been observed in experiments that combustion instability of low frequency (${\sim}$ 10Hz) results form the modulation of equivalence ratio at fuel injection hole when a pressure fluctuation propagates upwards along the channel of the burner under an unchoked fuel flow condition. In this study, a commercial program was used to determine how the fuel flow rate changed with respect to the pressure, velocity of the fuel flow and the mass fraction in a choked and an unchoked condition. The calculation focus on the upstream of the dump plane to know how the forced pressure with the fuel injection conditions affects the modulation of the equivalence ratio. Therefore, it is found that pressure fluctuation leads to oscillation of mass flow rate and then results in equivalence ratio modulation under the unchoked fuel flow condition.

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Approximate solution for a building installed with a friction damper : revisited and new result (마찰감쇠기가 설치된 건물 응답의 근사해 : 재 고찰 및 새로운 결과)

  • Min, Kyung-Won;Seong, Ji-Young;Lee, Sung-Kyung
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2009.10a
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    • pp.850-854
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    • 2009
  • Approximate analysis for a building installed with a friction damper is revisited to get insight of its dynamic behavior. Energy balance equation is used to have a closed analytical form solution of dynamic magnification factor (DMF) for the building with combined viscous and friction damping. It is found out that DMF is dependent on friction force ratio and resonance frequency. Linear transfer function from input external force to output building displacement is obtained by simplifying DMF equation. Root mean square of building displacement is derived under earthquake-like random excitation. Finally, design of friction damper is proposed by processing target control ratio, damping ratio factor, and friction force in sequence.

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A study on log-density ratio in logistic regression model for binary data

  • Kahng, Myung-Wook
    • Journal of the Korean Data and Information Science Society
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    • v.22 no.1
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    • pp.107-113
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    • 2011
  • We present methods for studying the log-density ratio, which allow us to select which predictors are needed, and how they should be included in the logistic regression model. Under multivariate normal distributional assumptions, we investigate the form of the log-density ratio as a function of many predictors. The linear, quadratic and crossproduct terms are required in general. If two covariance matrices are equal, then the crossproduct and quadratic terms are not needed. If the variables are uncorrelated, we do not need the crossproduct terms, but we still need the linear and quadratic terms.

A Study of Bearing Capacity and Settlement of Shallow Foundation by FEM (유한요소법에 의한 얕은 기초의 지지력 및 침하 특성 연구)

  • Park, Jong-Su;Park, Choon-Sik;Jang, Jeong-Wook
    • Proceedings of the Korean Geotechical Society Conference
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    • 2006.03a
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    • pp.1312-1319
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    • 2006
  • This thesis studied the scale effects on bearing capacity and settlement characteristics by using FEM. The conclusions of the study are as follows. 1) For sandy soil, the bearing capacity ratio increased in the form of logarithm as the foundation width increased. Hence application of static mechanic theory results in overestimation of the bearing capacity when the bearing capacity should be derived from plate loading test results. 2) In clayey soil, the characteristics of the bearing capacity associated with foundation width met Terzaghi's bearing capacity theory. 3) In sandy soil, the settlement ratio increased non-linearly as foundation width increased. However, in clayey soil, the settlement ratio increased linearly. 4) In ordinary soil, the foundation width - settlement ratio turned out to be close to that of sandy soil.

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