• 제목/요약/키워드: rate of resistance increase

검색결과 690건 처리시간 0.026초

혈액배양에서 분리된 임상적 주요 균주의 항균제사용량에 따른 내성률 변화 (Antimicrobial resistance rates changes according to the amount of the antimicrobial agent in clinically important strain isolated from blood cultures)

  • 김재중
    • 한국산학기술학회논문지
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    • 제17권5호
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    • pp.653-659
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    • 2016
  • 본 논문의 목적은 항균제 사용량(Defined Daily Dose. DDD)과 세균의 내성률(%)과의 상관성을 보고자 하였다. 항균제 내성은 최근 다제 내성균들의 증가로 인하여 감염증의 치료가 점점 더 어려워져 임상적으로 중대한 문제가 되고 있다. 그리고, 여러 요인들 중에서 항균제 오남용은 항균제 내성의 주요 원인이 되고 있다. 중부권지역의 일개 2차 대학병원의 입원환자를 대상으로 병원전산통계 자료와 진단검사의학과의 미생물 프로그램을 이용하여 2010년 1월부터 2014년 12월 까지 혈액배양에서 분리 동정된 Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli 균주에 대하여 항균제 사용량에 따른 균주의 내성률과의 상관성을 분석하기 위하여 균주 내성률과 항균제 사용량을 각각 조사하였다. 사용량에 따른 항균제 내성률은 pearson상관분석을 실시하였다. 그 결과 cefepime사용량과 cefepime 내성 E. coli에서 유의한 상관관계가 있었고(P<0.033;r=0.907), tobramycin사용량과 tobramycin 내성 E.coli에서도 유의한 음의 상관관계가 있었다(P<0.028;r=-0.917). Aminoglycoside계열 내성 A.baumannii가 유의한 음의 상관관계를 나타냈고(P<0.048;r=-0.881), aminoglycoside계열 내성 E. coli도 유의한 음의 상관관계를 나타냈다(P<0.001;r=-0.992). 결론적으로 항균제 사용량은 일부 세균에서 내성률과 상관성이 있었다.

Nd:YAG 레이저를 이용한 순티타늄판의 겹치기 용접성 (Lab Weldability of Pure Titanium by Nd:YAG Laser)

  • 김종도;곽명섭
    • Journal of Advanced Marine Engineering and Technology
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    • 제32권2호
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    • pp.315-322
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    • 2008
  • Titanium and its alloys have excellent corrosion resistance, high strength to weight ratios and creep properties in high temperature, which make them using many various fields of application. Especially, pure titanium, which has outstanding resistance for the stress corrosion cracking, crevice corrosion, pitting and microbiologically influenced corrosion, brings out to the best material for the heat exchanger, ballast tank, desalination facilities, and so on. Responding to these needs, welding processes for titanium are also being used GTAW, GMAW, PAW, EBW, LBW, resistance welding and diffusion bonding, etc. However, titanium is very active and highly susceptible to embrittlement by oxygen, nitrogen, hydrogen and carbon at high temperature, so it needs to shield the weld metal from the air and these gases during welding by non-active gas. In this study, it was possible to get sound beads without humping and spatter with a decrease of peak power according to increase of pulse width, change of welding speed and overlap rate for heat input control, and shield conditions at pulsed laser welding of titanium plates for Lap welding.

평판에 형성된 공기공동 특성에 관한 연구 (A Study on the Characteristics of an Air Cavity Attached Under a Flat Plate)

  • 김종현;오재용;서대원;이승희
    • 대한조선학회논문집
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    • 제48권5호
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    • pp.396-403
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    • 2011
  • The concept of an air lubrication has long been an object of attention since it can be utilized to reduce the frictional resistance, and what is more, it is eco-friendly. The present study examines the basic characteristics of an air cavity with intention of applying the air lubrication technology to the reduction of the resistance of a ship without excessive power increment. For the purpose, an air cavity was created at the bottom of a flat plate by injecting air behind a backward step and the hydrodynamic properties of the air cavity and the surrounding flow has been investigated experimentally and numerically. The influence of the step height and the air flow rate have been more carefully studied since they are presumed to be the main parameters affecting the characteristics of an air cavity. The results indicates that the shapes of the air cavities attached on the flat plate become "U" or "V" type depending on the incoming flow velocity and air flow rate. The study also confirms that the length of the air cavity increases with increase in air flow rate but there is a certain critical limit in the flow rate above which increase in the air cavity length is no more evident.

경질양극산화된 5083-H321 알루미늄 합금의 해수 내 액적충격침식부식 손상 연구 (Investigation of Liquid Droplet Impingement Erosion Corrosion based on the Flow Rate of Anodized 5083-H321 Al Alloy in Seawater)

  • 신동호;김성종
    • Corrosion Science and Technology
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    • 제19권6호
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    • pp.310-317
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    • 2020
  • This study investigated the damage to the specimen due to liquid droplet impingement erosion corrosion, which improved the corrosion resistance and durability via hard anodization of 5083-H321 aluminum alloy, which is widely used for small ships and marine structures. The experiment combined liquid droplet impingement erosion and electrochemical equipment with the flow rates in natural seawater solution. Subsequently, Tafel extrapolation of polarization curves was performed to evaluate damage due to the liquid droplet impingement erosion corrosion. The damaged surface was observed using a 3D microscope and a scanning electron microscope. The degree of pitting damage was measured using the Image J program, and the surface hardness was measured using the micro-Vickers hardness tester. The corrosion current density, area, depth, and ratio of the damaged areas increased with the increase in flow rate. The grain size of the damaged area at a flow rate of 20 m s-1 showed fewer and minor differences in height, and a smooth curved shape. The hardness of the damaged surface tended to decrease with increase in flow rate.

용해조건 및 합금원소 첨가에 따른 고규소 내산주철의 기계적 성질 및 부식속도의 변화 (Variations of Mechanical Properties and Corrosion Rate with Melting Conditions and Alloying Elements in High Silicon Cast Irons)

  • 김정철;한동운;백진현;백승한;문병문;신제식;이영국
    • 한국주조공학회지
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    • 제24권4호
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    • pp.209-216
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    • 2004
  • High silicon cast irons(HSCI) with the high acid resistance have been used for the prevention of acid corrosion occurring in various structures under acid conditions. However, the HSCI is only known as one of materials which have high acid resistance, but few work has dealt with this material in domestic. Therefore, in this study, the acid resistance of various cast irons with alloying elements and melting conditions have been examined, and studied the influences of the matrix structures, mechanical properties and morphologies of graphite. The results obtained in this study are as follows : In case of melting temperature, the mechanical properties of specimen manufactured with high temperature of $1650^{\circ}C$ showed higher value because the inclusion and impurity were removed. In case of pouring temperature, the mechanical properties of specimen fabricated below $1350^{\circ}C$ of pouring temperature showed higher value because the amount of gas absorption from atmosphere decreased during the solidification time. The corrosion rate decreased with increase in Si content. On the other hand, Mn addition appeared an opposite trend with Si.

인산 에스테르에 의한 탄소재료의 내산화 증진 효과 (Improvement of Oxidation-resistance of Graphite by Phosphate)

  • 김경자;조광연;박윤창;김태관;정윤중;임연수
    • 한국세라믹학회지
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    • 제36권5호
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    • pp.555-563
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    • 1999
  • 탄소재료의 산화저항성 증진을 위해 Tri-Butyl 인산 에스테르를 함참하였다. 시편은 함침전 초산으로 전처리 한 것과 흑연재 Raw Bulk(Raw)를 함침시켜 비교하므로써 초산 세척의 효과도 아울러 조사하였다. XPS와 FTIR을 사용하여 함침처리 전후의 탄소표면의 특성을 검토한 결과 Tn-butyl phosphale로 함침된 시편(RP)의 표면에는 P-O 그룹 및 -OH Band 등의 친수성이 강한 활성기가 존재하였다. 산세척한 시편을 함침한 탄소재(AP)는 Raw보다 산화게시온도가 약 120$^{\circ}C$ 향상되었고 산화율은 1000$^{\circ}C$에서 30% 감소된 효과를 보였다. 본실험에서 구한 Raw, 초산세척 시편, 초산처리후 함침한 시편들의 Arrbenius Plot으로부터 동일한 값의 기울기를 나타내어 탄소의 산화반응 요인중에 본실험에서 처리한 내산화과정은 탄소표면의 기본적 화학반응변화에 의한 효과로 보여지지 않는다.

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수소생산 고정화 생물 반응기의 특성(II) -연속 반응기에서의 총괄 효율인자 - (Characteristics of the Bioreactors of Hydrogen-producing Immobilized Cells (II) -Overall Effectiveness Factor in Continuous Reactors-)

  • 이명재;선용호;한정우;조영일
    • 한국미생물·생명공학회지
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    • 제16권6호
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    • pp.510-516
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    • 1988
  • 본 연구는 균주로 Rhodospirillum rubrum KS-301, 증식 제한 기질로 글루코오스, 고정화 담체로 Ca alginate를 사용한 고정화 생물 반응기를 조작할 때 담체에 의해 형성되는 물질전달 저항에 대한 도입 기질의 농도, 희석속도의 영향을 고찰하였다. 또한 효율인자를 평가하기 위해 속도식 변수를 구하였다. 충전층 반응기의 경우 외부 액막 물질전달 저항보다는 내부 물질전달 저항이 우세함을 알 수 있었고 총괄 효율인자는 희석속도의 증가에 따라 감소하였다. 연속 교반 탱크 반응기의 경우 외부 액막 물질전달 저항은 무시할 수 있으며 총괄 효율인자는 희석속도에 영향을 받지 않았다. 희석속도 0.2/h, 비드 반경 0.15cm, 초기 글루코오스 농도 1.0g/L의 실험조건에서 총괄 효율인자는 충전층 반응기와 연속 교반 반응기에서 각각 0.70과 0.77이었다.

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PEMFC 금속분리판의 내식성에 미치는 DLC 코팅층의 두께 및 결함의 영향 (Effects of Thickness and Defects of DLC Coating Layer on Corrosion Resistance of Metallic Bipolar Plates of PEMFCs)

  • 신동호;김성종
    • Corrosion Science and Technology
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    • 제23권3호
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    • pp.235-245
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    • 2024
  • DLC coatings have been widely applied in industrial fields that require high corrosion resistance due to their excellent mechanical characteristics and chemical stability. In this research, effects of DLC coating thickness and defects on corrosion resistance were investigated for application of metallic bipolar plates in polymer membrane electrolyte fuel cells (PEMFCs). Results revealed that a DLC coating thickness of 0.7 ㎛ could lead to a defect size reduction of about 75.9% compared to that of 0.3 ㎛.As a result of potentiodynamic polarization experiments, the current density under a potential of 0.6 V was measured to be less than 1 ㎂/cm2,which was an excellent value. Inparticular, the delamination ratio and the decrease rate of maximum pitting depth were up to 84.8% and 63.3%, respectively, with an increase in the DLC coating thickness. These results demonstrate that DLC coating thickness and defects are factors that can affect corrosion resistance of DLC coating and its substrate.

초음파 감쇠 및 전기저항 측정법에 의한 발전소 고온배관의 크리프손상 평가 (Nondestructive Creep Damage Evaluation of High-Temperature Pipelines by Ultrasonic Attenuation Measurement and Electric Resistance Methods)

  • 이인철;길두송;정계조;조용상;이상국
    • 한국해양공학회지
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    • 제13권3호통권33호
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    • pp.100-107
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    • 1999
  • Due to the high temperature and pressure, the materials of pipeline in power plant are degraded by creep damage. So far, many conventional measurement techniques such as replica method, electric resistance method, adn hardness test method for creep damage have been used. Among them, the replica method has mainly been used for the inspection of components. But this technique is restricted to the applications at the surface of the objects and cannot be used to material inside. In this paper, the measuring methods of evaluation by using ultrasonic attenuation and electric resistance for the creep detection of creep damage in the form of cavities on grain boundaries or intergranular microcracks were carried out. Absolute measuring method of quantitave ultrasonic attenuation technique for 1Cr0.5Mo material degradation was analyzed for determining the creep degradation steps using life prediction formula. As a result of measurement for creep specimens, we founded that the coefficient of utrasonic attenuation was increased as the increase of creep life fracton(${phi}c$) and the decreasing rate of wlwctric resistance was also increased.

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곡물(穀物)의 함수율(含水率) 변화(變化)에 따른 송풍저항(送風抵抗)에 관(關)한 연구(硏究) (Resistance to Airflow of Grain as Affected by Grain Moisture Content)

  • 김만수;김성래
    • Journal of Biosystems Engineering
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    • 제11권2호
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    • pp.55-65
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    • 1986
  • The resistance to the passage of airflow through various agricultural products is an important consideration in the design of an aeration or drying system. The amount of resistance to airflow varied widely from one kind of grain to another, and depended upon airflow rate, surface texture and shape of the particles, the size and configuration of voids, and foreign and fine material in the grain bed. The airflow rate was the major factor considered on this kind of study in the early stages. But these days, the studies on the resistance to airflow of grain affected by grain moisture content and foreign and fine material have been widely carried out. However the foreign an fine material in the grain bed could not be a major factor on the study in Korea because there were only a few grain process procedure after harvesting it. The objectives of this study were to investigate the effect of moisture content and airflow rate on airflow resistance to grain, and to develop a model to predict the static pressure drop across the grain bed as a function of moisture content and airflow rate. The rough rice varieties, Akibare, Milyang 15 (Japonica types), Samkwang, Backyang (Indica types)and covered barley variety, Olbori, which were harvested in 1985 were used in the experiment after cleaning them. Resistances to airflow of grain were investigated at four levels of moisture content (13-25%, wb.) for ten different airflow rates($0.01-0.15m^3/sm^2$). The results of this study are summarized as follows; 1. Theaverage bulk densities were $585.3kg/m^3$ for rough rice and $691.6kg/m^3$ for barley at the loose fill, and were $648.8kg/m^3$ for rough rice and $758.2kg/m^3$ for barley at the packed fill. The pressure drops at the packed fill beds were approximately 1.4 to 1.8 times higher than those at the loose fill beds. 2. The pressure drops across grain beds deceased with the increase of moisture content and increased with airflow rate. The decreasing rates of pressure drop across grain beds according to the moisture contents at the lower airflow rates were higher than those at the higher airflow rates, and the increasing rates of pressure drop according to the airflow rates at the lower moisture contents were higher those at higher moisture contents. 3. The pressure drop across barley bed were much higher than rough rice beds and the pressure drops across Japonica type rough rice beds were a little higher than Indica type. 4. The mathematical models to predict the pressure drop across grain beds as a function of moisture content and airflow rate were developed from these experiments.

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