• 제목/요약/키워드: radiation exposure dose

검색결과 1,108건 처리시간 0.026초

DIFFERENTIAL EXPRESSION OF RADIATION RESPONSE GENES IN SPLEEN, LUNG, AND LIVER OF RATS FOLLOWING ACUTE OR CHRONIC RADIATION EXPOSURE

  • Jin, Hee;Jin, Yeung Bae;Lee, Ju-Woon;Kim, Jae-Kyung;Lee, Yun-Sil
    • Journal of Radiation Protection and Research
    • /
    • 제40권1호
    • /
    • pp.25-35
    • /
    • 2015
  • We analyzed the differential effects of histopathology, apoptosis and expression of radiation response genes after chronic low dose rate (LDR) and acute high dose rate (HDR) radiation exposure in spleen, lung and liver of rats. Female 6-week-old Sprague-Dawley rats were used. For chronic low-dose whole body irradiation, rats were maintained for 14 days in a $^{60}Co$ gamma ray irradiated room and received a cumulative dose of 2 Gy or 5 Gy. Rats in the acute whole body exposure group were exposed to an equal dose of radiation delivered as a single pulse ($^{137}Cs$-gamma). At 24 hours after exposure, spleen, lung and liver tissues were extracted for histopathologic examination, western blotting and RT-PCR analysis. 1. The spleen showed the most dramatic differential response to acute and chronic exposure, with the induction of substantial tissue damage by HDR but not by LDR radiation. Effects of LDR radiation on the lung were only apparent at the higher dose (5 Gy), but not at lower dose (2 Gy). In the liver, HDR and LDR exposure induced a similar damage response at both doses. RT-PCR analysis identified cyclin G1 as a LDR-responsive gene in the spleen of rats exposed to 2 Gy and 5 Gy gamma radiation and in the lung of animals irradiated with 5 Gy. 2. The effects of LDR radiation differed among lung, liver, and spleen tissues. The spleen showed the greatest differential effect between HDR and LDR. The response to LDR radiation may involve expression of cyclin G1.

일반인들의 항공여객기 이용 시 우주방사선 피폭선량 비교 분석 (Analysis of Cosmic Radiation Dose of People by Abroad Travel)

  • 장동근;신상화
    • 대한방사선기술학회지:방사선기술과학
    • /
    • 제41권4호
    • /
    • pp.339-344
    • /
    • 2018
  • Humans received an exposure dose of 2.4 mSv of natural radiation per year, of which the contribution of spacecraft accounts for about 75%. The crew of the aircraft has increased radiation exposure doses based on cosmic radiation safety management regulations There is no reference to air passengers. Therefore, in this study, we measured the radiation exposure dose received in the sky at high altitude during flight, and tried to compare the radiation exposure dose received by ordinary people during flight. We selected 20 sample specimens, including major tourist spots and the capital by continent with direct flights from Incheon International Airport. Using the CARI-6/6M model and the NAIRAS model, which are cosmic radiation prediction models provided at the National Radio Research Institute, we measured the cosmic radiation exposure dose by the selected flight and departure/arrival place. In the case of exposure dose, Beijing was the lowest at $2.87{\mu}Sv$ (NAIRAS) and $2.05{\mu}Sv$ (CARI - 6/6M), New York had the highest at $146.45{\mu}Sv$ (NAIRAS) and $79.42{\mu}Sv$ (CARI - 6/6M). We found that the route using Arctic routes at the same time and distance will receive more exposure dose than other paths. While the dose of cosmic radiation to be received during flight does not have a decisive influence on the human body, because of the greater risk of stochastic effects in the case of frequent flights and in children with high radiation sensitivity Institutional regulation should be prepared for this.

의료영상 데이터에서의 피폭선량 표시 방법에 관한 고찰: DICOM 표준을 중심으로 (Study on Radiation Dose in the Medical Image Data Display Method - Focused on the DICOM Standard)

  • 김정수
    • 대한방사선기술학회지:방사선기술과학
    • /
    • 제38권4호
    • /
    • pp.483-489
    • /
    • 2015
  • 현대의 의료용 방사선 발생장치는 영상을 저장하고 전송하기 위해 의료영상 표준규격으로 Digital image communications in medicine(DICOM)을 채택하고 있다. DICOM 규격에서는 피폭선량 정보 표시를 위해 DICOM dose Structured Report(DICOM dose SR)를 표준으로 제정하여 사용하고 있다. 이와 더불어 DICOM Modality Performed Procedure Step(DIOCM MPPS) 정보와 DICOM tag 정보에서도 부분적인 피폭선량 정보를 표시하고 있다. 본 연구에서는 DICOM과 관련된 피폭선량정보 표시방법에 대해 고찰하고 의료정보 시스템간의 상호연동 테스트를 위한 Integrating the Healthcare Enterprise(IHE)의 Radiation Exposure Monitoring(REM) 프로파일에 대해 살펴보았다. 의료기관에서 의료방사선피폭선량정보에 대한 품질관리를 위해서는 DICOM 정보에서 표시되는 피폭선량 정보형식에 대한 이해가 반드시 수반되어야 하고 장비도입 단계에서 관련 규격에 대한 검토가 이루어져야 한다.

몬테칼로 시뮬레이션을 이용한 소아 핵의학검사 시 인체내부 장기선량 평가 (Evaluation Internal Radiation Dose of Pediatric Patients during Medicine Tests Using Monte Carlo Simulation)

  • 이동연;강영록
    • 대한방사선기술학회지:방사선기술과학
    • /
    • 제44권2호
    • /
    • pp.109-115
    • /
    • 2021
  • In this study, a physical evaluation of internal radiation exposure in children was conducted using nuclear medicine test(Renal DTPA Dynamic Study) to simulate the distribution and effects of the radiation throughout the tracer kinetics over time. Monte Carlo simulations were performed to determine the internal medical radiation exposure during the tests and to provide basic data for medical radiation exposure management. Specifically, dose variability based on changes in the tracer kinetic was simulated over time. The internal exposure to the target organ (kidney) and other surrounding organs was then quantitatively evaluated and presented. When kidney function was normal, the dose to the target organ(kidney) was approximately 0.433 mGy/mCi, and the dose to the surrounding organs was approximately 0.138-0.266 mGy/mCi. When kidney function was abnormal, the dose to the surrounding organs was 0.228-0.419 mGy/mCi. This study achieved detailed radiation dose measurements in highly sensitive pediatric patients and enabled the prediction of radiation doses according to kidney function values. The proposed method can provide useful insights for medical radiation exposure management, which is particularly important and necessary for pediatric patients.

우리나라 응급의료센터 응급구조사의 직업적 방사선 노출 (Occupational Radiation Exposure of Emergency Medical Technicians in Emergency Medical Centers in Korea)

  • 이현경;박정임
    • 한국산업보건학회지
    • /
    • 제27권3호
    • /
    • pp.170-179
    • /
    • 2017
  • Objectives: This study aims to investigate the occupational radiation exposures of emergency medical technicians(EMTs) in emergency medical centers in Korea. The results will provide a basis for developing prevention programs to minimize adverse health effects relating to radiation exposure among emergency medical technicians working in this area. Methods: Radiation exposure doses were measured for twenty-two EMTs working in six emergency medical centers. Thermo Luminescent Dosimeters(TLD) were placed on three representative body parts, including chest, neck, and a finger. Measurements were conducted over the entire working hours of the participants for foor weeks. Dosimeters were analyzed according to a standard method by a KFDA-designated lab. Detection rate, annual radiation exposure dose, and relative levels to dose limit were derived based on the measured doses from the dosimeters. SPSS/Win 18.0 software(IBM, US) was used for statistical analysis. Results: Detection rates were 45.5%, 36.4%, and 45.5% for the dosimeters sampled from chest, neck, and a finger, respectively. The average annual doses were $2.39{\pm}3.44mSv/year$(range 0.38-10.0 mSv/year) for the chest, $2.72{\pm}3.05mSv/year$(2.00-11.34) for the neck, and $20.98{\pm}17.57mSv/year$(1.25-53.50) for the hand dose. The average annual eye dose was estimated to $3.61{\pm}2.37mSv/year$(1.50-8.34). The exposure dose levels of EMTs were comparable to those of radiologists, who showed relatively higher radiation dose among health care workers, as reported in another study. Conclusions: EMTs working in emergency medical centers are considered to be at risk of radiation exposure. Although the radiation exposure dose of EMTs does not exceed the dose limit, it is not negligible comparing to other professionals in health care sectors.

소아 X선 촬영조건 변화에 따른 소아 및 촬영보조자 선량 (Doses of Pediatric and X-ray Examination Assistants according to Changes in Pediatric X-ray Exposure Conditions)

  • 장범진;남하윤;신혜민;윤동민;이승국;장인화;김성철
    • 대한방사선기술학회지:방사선기술과학
    • /
    • 제46권5호
    • /
    • pp.409-415
    • /
    • 2023
  • Although pediatric X-ray examinations are continuously increasing, there are not many studies on the radiation exposure to children and X-ray examination assistants according to X-ray Exposure conditions. Accordingly, we measured the radiation exposure dose of pediatric and X-ray examination assistants according to the standard guidelines and clinical average X-ray Exposure conditions when X-ray examination 10-year-old children. The effective dose and organ dose to pediatric were measured using an Dose area production meter and Monte Carlo-based PCXMC program, and the exposure dose of X-ray examination assistants was measured using an ion-chamber. When performing abdominal supine AP projection, the effective dose to children was up to 2.38 times higher under clinical average X-ray Exposure conditions than the standard guidelines. In addition, during abdominal supine AP projection, the radiation exposure dose to the X-ray examination assistants was highest on the hands at 0.0148 ~ 0.0709 mSv, and exposure dose could be reduced by up to 35% when wearing protective gloves. In conclusion, because the X-ray Exposure conditions used in clinical are unnecessarily high, unnecessary medical radiation exposure could be reduced if appropriate X-ray Exposure conditions and the radiation field area were minimized and the assistant wore shielding gloves.

핵의학과 주사와 분배업무 작업종사자 및 수시출입자 피폭선량연구 (A Study on Exposure Dose from Injection Work and Elution Work for Radiation Workers and Frequent Workers in Nuclear Medicine)

  • 주용진;동경래;최은진;곽종길;류재광;정운관
    • 방사선산업학회지
    • /
    • 제11권1호
    • /
    • pp.47-54
    • /
    • 2017
  • Compared to other occupations, there is a greater risk of exposure to radiation due to the use of radioisotopes in nuclear medicine for diagnostic evaluations and therapy. To consider ways to reduce exposure dose for those in nuclear medicine involved in injection work and elution work among radiation workers as well as for sanitation workers and trainees among frequent workers an investigation into exposure dose and situational analysis from changes in yearly exposure dose evaluations, changes in work environment and changes in forms of inspection were conducted. Exposure dose measurements were taken by using EPD MK2 worn during working hours for one injection worker, one elution worker, two sanitation workers, and one trainee at a general hospital in the Seoul area for three days from July 18th to 20th 2016. Radiation from radioisotopes which are a part of nuclear medicine can significantly affect not only radiation workers who deal with radioisotopes directly but also frequency works as well. According to this study the annual dose limit for elution workers and injection workers were considered safe as the amount of exposure was not large enough to have a significant effect. The limits of this study consist in the duration of this study and the quantity of participants. Also there was a limitation of the measurement device involving accumulated exposure, where the EPD MK2 cannot check the changes in exposure according to a particular activity.

Analysis of Cosmic Radiation Exposure for Domestic Flight Crews in Korea

  • Ahn, Hee-Bok;Hwang, Junga;Kwak, Jaeyoung;Kim, Kyuwang
    • Journal of Astronomy and Space Sciences
    • /
    • 제39권2호
    • /
    • pp.51-57
    • /
    • 2022
  • Cosmic radiation exposure of the flight crews in Korea has been managed by Radiation Safety Management around Living Life Act under Nuclear Safety and Security Commission. However, the domestic flight crews are excluded from the Act because of relatively low route dose exposure compared to that of international flight crews. But we found that the accumulated total annual dose of domestic flight crews is far from negligible because of relatively long total flight time and too many flights. In this study, to suggest the necessity of management of domestic flight crews' radiation exposure, we statistically analyzed domestic flight crew's accumulative annual dose by using cosmic radiation estimation models of the Civil Aviation Research Institute (CARI)-6M, Nowcast of Atmospheric Ionizing Radiation for Aviation Safety (NAIRAS), and Korean Radiation Exposure Assessment Model (KREAM) and compared with in-situ measurements of Liulin-6K LET spectrometer. As a result, the average exposure dose of domestic flight crews was found to be 0.5-0.8 mSv. We also expect that our result might provide the basis to include the domestic flight crews as radiation workers, not just international flight attendants.

일반병원과 치과병원과의 방사선 관계종사자 피폭선량 비교분석 (A Comparative Analysis of Exposure Doses between the Radiation Workers in Dental and General Hospital)

  • 양남희;정운관;동경래;최은진;주용진;송하진
    • 방사선산업학회지
    • /
    • 제9권1호
    • /
    • pp.47-55
    • /
    • 2015
  • Research and investigation is required for the exposure dose of radiation workers to work in the dental hospital as increasing interest in exposure dose of the dental hospital recently accordingly, study aim to minimize radiation exposure by making a follow-up study of individual exposure doses of radiation workers, analyzing the status on individual radiation exposure management, prediction the radiation disability risk levels by radiation, and alerting the workers to the danger of radiation exposure. Especially given the changes in the dental hospital radiation safety awareness conducted the study in order to minimize radiation exposure. This study performed analyses by a comparison between general and dental hospital, comparing each occupation, with the 116,220 exposure dose data by quarter and year of 5,811 subjects at general and dental hospital across South Korea from January 1, 2008 through December 31, 2012. The following are the results obtained by analyzing average values year and quarter. In term of hospital, average doses were significantly higer in general hospitals than detal ones. In terms of job, average doses were higher in radiological technologists the other workes. Especially, they showed statistically significant differences between radiological technologists than dentists. The above-mentioned results indicate that radiation workers were exposed to radiation for the past 5 years to the extent not exceeding the dose limit (maximum $50mSv\;y^{-1}$). The limitation of this study is that radiation workers before 2008 were excluded from the study. Objective evaluation standards did not apply to the work circumstance or condition of each hospital. Therefore, it is deemed necessary to work out analysis criteria that will be used as objective evaluation standard. It will be necessary to study radiation exposure in more precise ways on the basis of objective analysis standard in the furture. Should try to minimize the radiation individual dose of radiation workers.

X선 촬영시 피폭선량 및 실내공간선량에 관한 연구 (A Study on the Exposure and Free Space Scattered Dose in Radiography)

  • 안봉선;이규은;선종률
    • 대한방사선기술학회지:방사선기술과학
    • /
    • 제21권2호
    • /
    • pp.26-30
    • /
    • 1998
  • We tried to study in order to furnish the data for medical exposure dose and scattered ray in radiography. As the tables(from 1 to 3) show, we can presume, by means of a concrete numerical value, the amount of results affected by patient radiation exposure dose and somatic effect in radiography. However, there are many difficulties in the difference of exposure factor in each hospital, the accuracy of measuring by tracebility, shortage of exposure dose data especially in the area of children, and portable radiography, etc. In the radiation examination, it is considered if the gained benefit to the patient due to radiation is more than the risk of radiation, then the medical exposure is thought to be justified. Therefore, the radiotechnologists should continually make an effort to develop and study new techniques so as to reduce patient exposure dose.

  • PDF