Browse > Article
http://dx.doi.org/10.17946/JRST.2021.44.2.109

Evaluation Internal Radiation Dose of Pediatric Patients during Medicine Tests Using Monte Carlo Simulation  

Lee, Dong-yeon (Dongnam Institute of Radiological & Medical Sciences)
Kang, Yeong-rok (Dongnam Institute of Radiological & Medical Sciences)
Publication Information
Journal of radiological science and technology / v.44, no.2, 2021 , pp. 109-115 More about this Journal
Abstract
In this study, a physical evaluation of internal radiation exposure in children was conducted using nuclear medicine test(Renal DTPA Dynamic Study) to simulate the distribution and effects of the radiation throughout the tracer kinetics over time. Monte Carlo simulations were performed to determine the internal medical radiation exposure during the tests and to provide basic data for medical radiation exposure management. Specifically, dose variability based on changes in the tracer kinetic was simulated over time. The internal exposure to the target organ (kidney) and other surrounding organs was then quantitatively evaluated and presented. When kidney function was normal, the dose to the target organ(kidney) was approximately 0.433 mGy/mCi, and the dose to the surrounding organs was approximately 0.138-0.266 mGy/mCi. When kidney function was abnormal, the dose to the surrounding organs was 0.228-0.419 mGy/mCi. This study achieved detailed radiation dose measurements in highly sensitive pediatric patients and enabled the prediction of radiation doses according to kidney function values. The proposed method can provide useful insights for medical radiation exposure management, which is particularly important and necessary for pediatric patients.
Keywords
Internal radiation dose; Monte-carlo method; Nuclear medicine; Pediatric;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Lee DY, Lee JS. Evaluation of the space scattered dose according to the position of the radiation workers in mammography room. Journal of Radiological Science and Technology. 2016;39(3):297-303.   DOI
2 Pelowitz DB. MCNP6 user's manual version 1.0: LA-CP-13-00634 Rev. 0. Los Alamos National Laboratory; 2013.
3 10. ICRP. Recommendations of the ICRP. ICRP Publication 26. Ann. ICRP 1 (3);1977.
4 ICRP. Limits for intakes of radionuclides by workers. ICRP Publication 30 (Part 1). Ann. ICRP. 1979;2(3-4).
5 ICRP. Human respiratory tract model for radiological protection. ICRP Publication 66. Ann. ICRP. 1994;24(1-3).
6 ICRP. Radiation dose to patients from radiopharmaceuticals-Addendum 3 to ICRP Publication 53. ICRP Publication 106. Ann. ICRP. 2008;38(1-2).
7 Piepsz A, Ham HR. (eds.). Pediatric applications of renal nuclear medicine. Seminars in Nuclear Medicine, Elsevier; 2006.
8 Chadwick MB, Herman M, Oblozinsky P, Dunn ME, Danon Y, Kahler A, et al. ENDF/B-VII. 1 nuclear data for science and technology: Cross sections, covariances, fission product yields and decay data. Nuclear Data Sheets. 2011;112(12):2887-996.   DOI
9 National Kidney Foundation. Clinical practice guidelines for chronic kidney disease: Evaluation, classification and stratification. K/DOQI clinical practice guidelines. Am J Kidney Dis. 2002;39:S1-266.
10 Qi Y, Hu P, Xie Y, Wei K, Jin M, Ma G, et al. Glomerular filtration rate measured by 99mTc-DTPA renal dynamic imaging is significantly lower than that estimated by the CKD-EPI equation in horseshoe kidney patients. Nephrology. 2016;21(6):499-505.   DOI
11 Han EY, Bolch WE, Eckerman KF. Revisions to the ORNL series of adult and pediatric computational phantoms for use with the MIRD schema. Health Physics. 2006;90(4):337-56.   DOI
12 ICRP. Basic anatomical and physiological data for use in radiological protection reference values. ICRP Publication 89. Ann. ICRP. 2002;32(3-4).
13 White DR, Griffith RV, Wilson IJ. Report 46. Journal of the International Commission on Radiation Units and Measurements. 2016;os24(1):NP-NP.
14 Schwarz AL, Carter LL. MCNP/MCNPX visual editor computer code manual for vised version 24E (Complied withMCNPX version 2.7). Radiation Safety Information Computational Center; 2011.
15 Riper V. SABRINA user's guide. LA-UR-93-3696;1993.
16 ICRP. The 2007 recommendations of the international commission on radiological protection. ICRP Publication 103. Ann. ICRP. 2007;37(2-4).
17 Theis C, Buchegger KH. SimpleGeo solid modeler 4.3. Simple-GeoSimpleGeo; 2011.
18 ICRP. Radiation dose to patients from radiopharmaceuticals (Addendum to ICRP Publication 53). ICRP Publication 80. Ann. ICRP. 1998;28(3).
19 Fahey FH, Goodkind AB, Plyku D, Khamwan K, O'Reilly SE, Cao X, et al. (eds.). Dose estimation in pediatric nuclear medicine. Seminars in Nuclear Medicine, Elsevier; 2017.
20 ICRP. 1990 Recommendations of the international commission on radiological protection. ICRP Publication 60. Ann. ICRP. 1991;21(1-3).
21 Lee JS, Kim YS, Kim MG, Kim JS, Lee SY. Evaluation of Absorbed dose for the right lung and surrounding organs of the computational human phantom in brachytherapy by monte carlo simulation. Journal of Radiological Science and Technology. 2020;43(6):443-451.   DOI
22 Fahey FH, Goodkind A, Treves ST, Grant FD. Nuclear medicine and radiation protection. Journal of Radiology Nursing. 2016;35(1):5-11.   DOI
23 Seon JR, Gil JW. Study on development of patient effective dose calculation program of nuclear medicine examination. Journal of the Korea Academia-Industrial Cooperation Society. 2017;18(3):657-65.   DOI
24 Mettler Jr. FA, Huda W, Yoshizumi TT, Mahesh M. Effective doses in radiology and diagnostic nuclear medicine: A catalog. Radiology. 2008;248(1):254-63.   DOI