• 대한한방내과학회지
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• 제24권2_4호
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• pp.1067-1074
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• 2003

Objectives : This study was designed to evaluate the effects of traditional oriental therapies(TOT) on advanced gastric cancer(AGC) patient with metastasis to liver. Methods : We retrospectively analyzed the medical record of a case of AGC patient in stage IV with metastasis to liver who had been treated with TOT for 5 months continuously in East-West Cancer Center of Oriental Hospital of Daejeon University from 5 March 2003 through 22 July 2003. Results : After treated with TOT for the 5 months, most of symptoms were disappeared or improved and tumor size was decreased on abdominal CT compared with the previous result. The hematological results and tumor markers were not increased. Conclusions : From the above results, it could be suggested that TOT have effects on improving symptoms and quality of life as a supportive or curative therapy for AGC patients.

• 한국임상약학회지
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• 제20권3호
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• pp.193-199
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• 2010

Tacrolimus, an immunosuppressant prescribed against graft-versus-host disease (GVHD) in patients with allogeneichematopoietic stem cell transplantation (HSCT), is affected to change its pharmacokinetic properties by various factors. For this reason, it is needed a close monitoring to adjust dosage amount in order to optimize the blood concentration of tacrolimus is located within the effective range. According to our in-house study, 62% of HSCT-patients were needed dosage-adjustment and it is necessary to optimize the current immunosuppressive regimen in clinical settings. A retrospective study was designed to evaluate the dosing regimen (converting ratio of IV:PO=1:4) of tacrolimus in HSCT patients (n=62). After collecting data from patient's profile and medical record, pharmacokinetic parameters were calculate and compared between the estimated and the actual values in the selected subjects (n=58). It was found that the bioavailabilty (BA) of oral tacrolimus was 40.5% very much different from that is known as 25%. It implies that the current protocol has a potent risk causes dose-related toxicities to the patients. Furthermore, analyses among factors demonstrated that there was no statistical significance between BA of tacrolimus and the variable factors. In the clinical perspectives, the current converting ratio of tacrolimus in patients with HSCT to be re-considered and an appropriate and optimal alternative regimen should be adopted to prevent GVHD and to increase the quality of life of patients.

• Advances in nano research
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• 제12권6호
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• pp.549-566
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• 2022

Mining of ore minerals (sfalerite, cinnabar, and chalcopyrite) from the old mine has led in significant environmental effects as contamination of soils and plants and acidification of water. Also, nanoparticles (NP) have obtained global importance because of their widespread usage in daily life, unique properties, and rapid development in the field of nanotechnology. Regarding their usage in various fields, it is suggested that soil is the final environmental sink for NPs. Nanoparticles with excessive reactivity and deliverability may be carried out as amendments to enhance soil quality, mitigate soil contaminations, make certain secure land-software of the traditional change substances and enhance soil erosion control. Meanwhile, there's no record on the usage of Nano superior substances for mine soil reclamation. In this study, five soil specimens have been tested at 4 sites inside the region of mine (<100 m) to study zeolites, and iron sulfide nanoparticles. Also, through using Artificial Neural Network (ANN) and Extreme Learning Machine (ELM), this study has tried to appropriately estimate the mechanical properties of soil under the effect of these Nano particles. Considering the RMSE and R2 values, Zeolite Nano materials could enhance the mine soil fine through increasing the clay-silt fractions, increasing the water holding capacity, removing toxins and improving nutrient levels. Also, adding iron sulfide minerals to the soils would possibly exacerbate the soil acidity problems at a mining site.

• Journal of Preventive Medicine and Public Health
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• 제34권1호
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• pp.21-27
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• 2001

Objectives : To develop a model that will predict the mortality of patients undergoing Coronary Artery Bypass Graft (CABG) and evaluate the perfermance of hospitals. Methods : Data from 564 CABGs peformed in six general hospitals were collected through medical record abstraction by registered nurses. Variables studied involved risk factors determined by severity measures. Risk modeling was performed through logistic repression and validated with cross-validation. The statistical performance of the developed model was evaluated using c-statistic, $R^2$, and Hosmer-Lemeshow statistic. Hospital performance was assessed by severity-adjusted mortalities. Results : The developed model included age, sex, BUN, EKG rhythm, Congestive Heart Failure at admission. acute mental change within 24 hours, and previous angina pectoris history. The c-statistic and $R^2$ were 0.791 and 0.001, respectively. Hosmer-Lemeshow statistic was 10.3(p value=0.2415). One hospital had a significantly higher mortality rate than the average mortality rate, while others were net significantly different. Conclusion : Comparing the quality of service by severity adjusted mortality rates, there were significant differences in hospital performance. The severity adjusted mortality rate of CABG surgery may He an indicator for evaluating hospital performance in Korea.

• 한국병원경영학회지
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• 제25권1호
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• pp.46-57
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• 2020

Objectives: The purpose of this study is to evaluate the factors affecting patient satisfaction for the nursing service of comprehensive nursing care service unit in Tertiary hospital Methods: This study employed a descriptive survey to investigate the nursing satisfaction and the study data was collected from 74 patients among 83 patient who were admitted to the nursing care integration service ward of an tertiary hospital for 10 days from May 9, 2018 to May 19, 2018. Data was analyzed by descriptive statistics, t-test, ANOVA, and multiple linear regression using SPSS 21 program. Results: The average with nursing satisfaction was significantly different according to marriage type and KPCS level. It was found that physical factor and educational factor have statistically significant effect on nursing satisfaction. As physical care increase by one unit, patient satisfaction increase by 0.226(95% CI; 0.061-0.390) and also satisfaction increase by 0.443(95% CI; 0.070-0.816) as education care increase by one unit. Conclusions: As a result of study, it was found that it is necessary to provide patients with more careful nursing service in physical and educational perspective, in order to improve the service quality of comprehensive nursing care service unit.

• 대한의용생체공학회:의공학회지
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• 제21권3호
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• pp.255-260
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• 2000

본 연구는 중환자실, 응급실, 수술실등 병실내에서 환자를 구속하지 않고. 무선으로 환자의 활력징후 신호등을 관찰할 수 있는 생체신호 무선 전송장치를 설계 제작하는데 목적을 두었다. 본 무선 환자감시장치는 활력징후 신호 수집기, 무선 송수신 장치 및 활력징후 관찰기로 구성된다. 활력징후 신호 수집부는 생체신호를 증폭하기 위한 아날로그신호 증폭기와 디지털데이터 변환을 위한 단일 칩 마이크로 컨트롤러로 구성된다. 전송신호의 품질을 확보하고 신호처리 및 구성이 간단하여 저 비용으로 구성할 수 있는 주파수편이변조(FSK) 방법을 사용하였고 디지털신호는 UHF 대역의 미약 무선주파수에 의하여 송수신되었다. 활력징후 신호 관찰기는 무선 수신기에 의해 디지털 데이터를 복조하고 활력징후 신호를 상시 모니터링하기 위한 액정모니터(LCD) 및 신호를 기록하기 위한 감열기록장치(thermal Printer)로 설계 제작되었다.

• Nutrition Research and Practice
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• 제9권3호
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• pp.278-287
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• 2015

BACKGROUND/OBJECTIVES: Diet plays an important role in growth and development of children. However, dietary intakes of children living in either rural or urban areas can be influenced by household income. This cross-sectional study examined energy, nutrient and food group intakes of 749 urban children (1-10 years old) by household income status. SUBJECTS/METHODS: Children's dietary intakes were obtained using food recall and record for two days. Diet adequacy was assessed based on recommended intakes of energy and nutrients and food group servings. RESULTS: For toddlers, all nutrients except dietary fiber (5.5 g) exceeded recommended intakes. Among older children (preschoolers and school children), calcium (548 mg, 435 mg) and dietary fiber (7.4 g, 9.4 g) did not meet recommendations while percentage of energy from total fat and saturated fats exceeded 30% and 10%, respectively. The mean sodium intakes of preschoolers (1,684 mg) and school children (2,000 mg) were relatively high. Toddlers in all income groups had similar energy and nutrient intakes and percentages meeting the recommended intakes. However, low income older children had lowest intakes of energy (P < 0.05) and most nutrients (P < 0.05) and highest proportions that did not meet recommended energy and nutrient intakes. For all food groups, except milk and dairy products, all age groups had mean intakes below the recommended servings. Compared to middle and high income groups, low income preschoolers had the lowest mean intake of fruits (0.07 serving), meat/poultry (0.78 serving) and milk/dairy products (1.14 serving) while low income toddlers and school children had the least mean intake of fruits (0.09 serving) and milk/dairy products (0.54 serving), respectively. CONCLUSION: Low socioeconomic status, as indicated by low household income, could limit access to adequate diets, particularly for older children. Parents and caregivers may need dietary guidance to ensure adequate quantity and quality of home food supply and foster healthy eating habits in children.

• 한국산학기술학회논문지
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• 제11권9호
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• pp.3366-3374
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• 2010

본 연구는 일개 지역의 노인을 대상으로 고혈압과 당뇨병 유무에 따른 건강관리 및 인식 패턴을 파악하고자 하였다. 고혈압, 당뇨병 유무에 다른 분석 중 군간 유의하게 나타난 생존변수 성별, 결혼상태, 직업, 건강관리방법, 연령대를 기초로 만성질환에 따른 패턴을 CART로 연구하였다. 직업군 패턴 결과 농업 직업군에서는 당뇨병이 가장 높은 빈도를 나타냈으나 어업, 공무원 직업군에서는 정상군이 가장 높은 빈도를 나타났다. 직업군이 상업 또는 기타에서는 연령에 80, 90대로 점차 갈수록 당뇨병의 발생 빈도는 높아지는 것으로 나타났다. 최근 들어 노인 인구가 증가하고 있는 현실에서 노인들의 질병과 활동제한으로 건강에 문제가 발생하고 있는 시점에서 생활기능의 증가를 통하여 노인의 삶을 높이고, 노인들의 삶의 질적인 면까지 고려하여 건강하고 만족하는 생활을 하면서 여생을 보낼 수 있도록 하여야 할 것이다.

• 한국방사선학회논문지
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• 제6권2호
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• pp.143-149
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• 2012

오늘날 의료영상매체의 획기적인 발전으로 각 병원에서 최신 의료장비를 도입함으로써 첨단화, 디지털화로 급변하는 추세이다. 이러한 움직임에 발맞추어 방사선 종양학과에서도 CR system을 도입하여 film system의 단점을 보완하고 병원에서 사용하고 있는 Picture Archiving and Communication System(PACS)과 Electronic Medical Record (EMR) , 그리고 Radiation therapy Treatment Planning system(RTP)의 network를 원활히 하여 업무효율 증대 및 환자에 대한 의료의 질 개선과 서비스 향상을 이루고자 하고 있는데, 방사선 종양학과의 Computed Radiography system(CR system)을 이용하여 PACS에 통합한 사례를 소개하고 그 유용성을 평가하고자 한다. 의료용 선형가속기인 MEVATRON-MX를 이용하여 현재 시행하고 있는 정도관리 중 Gantry, Collimator Star Shot, Light vs. Radiation Field Accuracy, HDR QA(Dwell position accuracy)를 시행하여 PACS 상에 구현하였고 모니터 상에서 디지털 영상을 통한 QA가 가능한지 확인하였다. 또한, 현재 S병원에서 사용 중인 Operation Control System(OCS)과 연동하여 치료에 필요한 코드를 각각의 치료에 부과하여 네트워크로 연결, CR상에 입력한 order가 나타나도록 하였으며, Planning System인 Pinacle과 PACS상의 지원 data 오류를 해결하여 PACS 상에서도 Planning 영상을 볼 수 있도록 하였다. CR system을 이용하여 L-gram, simulation image, planning image를 병원 내 어느 곳에서나 영상을 조회하고 볼 수 있게 PACS에 통합 구축되어있다. Filmless 환경에서 Dosimetry용 IP를 이용하여 Light/Radition field size 일치, gantry rotation axis의 정확성, collimator rotation axis의 정확성, brachy therapy의 Dwell position check등 QA의 시행이 가능하였다. CR system을 이용하여 방사선 종양학과에서 얻어지는 영상을 PACS에 통합함으로써 작업시간 단축과 그에 따른 불필요한 인력소모의 감소 등으로 인하여 업무효율이 증대되었지만 향후 환자정보에 대한 보안을 필요로 한다.

• 한국의료질향상학회지
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• 제5권1호
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• pp.128-138
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• 1998

Background : There is increased recognition that rigorous approach to functional assessment will complement the assessment of clinical status. This study is to develop the appropriate visual function index in Korean patients with cataracts by the assessment of the reliability, validity of visual function indexes including VF-14. Methods : An prospective study was performed with 92 patients who had undergone either one eye or both eye cataract surgery by 3 ophthalmologists practicing at a university hospital. Patients were interviewed. and clinical data were obtained. Doctors were questioned with self-entered questionnaire forms. Medical record was examined to understand surgery process. The survey was conducted at 1-2 days before cataract surgery. Results : We used following measures : 7 visual function indexes, global measures of patients' trouble and satisfaction with vision, and best-corrected visual acuity(VA) in each eye. 7 visual function indexes showed a high internal consistency reliability (Cronbach's alpha coefficients ${\geq}$ 0.86). The better visual acuity(operated eye, better eye), the higher patient satisfaction with vision, the lower symptom score, the lower patient trouble with vision was correlated with preoperative visual function index scores. Among 7 indexes, VF-12 with the exclusion of 2 items drivings from VF-14 is a high Cronbach's alpha coefficient and correlation coefficient and the highest $R^2$. Conclusion : We conclude that VF-12 is reliable and valid in Korea. So we suggest that in Korea, all items of VF-14, the visual function index, which is in use internationally, ought to be surveyed and VF-12 which has been excluded by 2 items of drivings from VF-14 ought to be used for analysis.