• The Korean Journal of Physiology
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• v.28 no.2
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• pp.233-240
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• 1994

In this study, it was investigated whether immortalized proximal tubule cells transformed with pRSVT could survive through the numerous passages. Results were as follows: 1. The cells transfected with pRSVT formed rapidly growing, multilayered colonies within 2 weeks in a hormone defined medium. Domes were also observed in some of the cultures. 2. r-glutamyl transpeptidase activity was equivalent to that observed in primary renal proximal tubule cell cultures. 3. Transformed cells with pRSVT form tubules in matrigel following 20 passages. 4. Genomic DNA of transformants was digested with either the restriction enzyme Xba or BamH1. A band of approximately 7.5kb was detected with Xba. Three BamH1 bands were detected at approximately 15 kb, 6.5 kb, and 3 kb.

• Archives of Pharmacal Research
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• v.22 no.4
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• pp.367-371
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• 1999

Effects of several durgs on rabbit renal proximal tubules were examined for the applicability of renal dipeptidase (RDPase, EC 3. 4. 13. 11) release as a model system to study nephrotoxicity. The proximal tubule prepared by the method of Taub (1990) released RDPase spontaneously in the control experiment which was confirmed by Western blotting. RDPase was also released form cisplatin, lipopolysaccardie (LPS), and indomethacin-treated tubules. Gentamicin inhibited RDPase release in a concentration-dependent manner. This RDPase release system may not be a general model to screen nephrotoxicity but could be a useful source of RDPase purification in a simple and inexpensive way.

• Journal of Korean Foot and Ankle Society
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• v.25 no.3
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• pp.141-144
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• 2021

More than 120 surgical methods for the correction of hallux valgus deformities have been reported. For the correction of moderate to severe hallux valgus deformities with aesthetic demands, minimally invasive surgery at the proximal area can be considered. This paper reports a case of moderate hallux valgus deformity treated by a minimally invasive proximal transverse metatarsal osteotomy followed by intramedullary plate fixation.

• Bulletin of the Korean Mathematical Society
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• v.56 no.3
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• pp.757-777
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• 2019

In this paper, we study the convergence analysis of the sequences generated by the proximal point method for an infinite family of pseudo-monotone equilibrium problems in Banach spaces. We first prove the weak convergence of the generated sequence to a common solution of the infinite family of equilibrium problems with summable errors. Then, we show the strong convergence of the generated sequence to a common equilibrium point by some various additional assumptions. We also consider two variants for which we establish the strong convergence without any additional assumption. For both of them, each iteration consists of a proximal step followed by a computationally inexpensive step which ensures the strong convergence of the generated sequence. Also, for this two variants we are able to characterize the strong limit of the sequence: for the first variant it is the solution lying closest to an arbitrarily selected point, and for the second one it is the solution of the problem which lies closest to the initial iterate. Finally, we give a concrete example where the main results can be applied.

• Archives of Plastic Surgery
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• v.46 no.1
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• pp.84-87
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• 2019

With the recent development in microsurgery, the use of a perforator flap has been widely implemented. If the length of the ALT flap pedicle is insufficient despite adequate preoperative planning, pedicle length extension is necessary. We planned for a reverse ALT free flap using the distal vessel of the descending branch for pedicle length extension in the case of ALT perforator branch originating from the proximal portion of the descending branch. For the management of venous congestion, the distal venae comitantes were anastomosed to the proximal venous stump in an antegrade manner, successfully resolving the venous congestion. Modified reverse-flow ALT free flap, wherein the venae comitantes are anastomosed to the proximal vein stump, is a good option that allows for relatively simple pedicle extension within the same operative field when securing an adequate pedicle length is difficult because of the origin of the perforator from the proximal descending branch, unlike the initial surgical plan.

• Clinical Pain
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• v.19 no.2
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• pp.111-115
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• 2020

We report a case of a healthy 38-year-old man presenting with insufficiency fracture of proximal tibia associated with unrecognized osteoporosis. Radiologic bone DEXA (Dual Energy X-ray Absorptiometry) assessment revealed osteoporosis, but the patient displayed no apparent risk factors for insufficiency fractures and osteoporosis except for a history of smoking. Following right proximal tibial open reduction and internal fixation, the patient commenced smoking cessation and began taking alendronate. The patient was treated for gait rehabilitation, which included quadriceps strengthening exercises and his condition improved with independent walking. This report highlights an unusual site of proximal tibial insufficiency fractures and the potential effect of smoking on low bone mineral density in a young male patient.

• Nonlinear Functional Analysis and Applications
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• v.27 no.3
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• pp.533-551
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• 2022

In this paper, we introduce several types 𝛼-𝜓 interpolative proximal contractions and provide some sufficient conditions to prove the existence of best proximity points for these contractions in metric spaces. In the case of proximal contraction of the first kind, these metric spaces are not necessarily complete. Meanwhile, some new results can derive from our results. Finally, some examples are provided to show the validity of our results.

• Clinics in Shoulder and Elbow
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• v.26 no.2
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• pp.205-207
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• 2023

A Monteggia fracture is a proximal ulnar fracture with proximal radioulnar ligamentous instability. While there is no precise definition, Monteggia-equivalent fractures are generally considered Monteggia fractures accompanied by radial head fractures. These are rare. In this study, we report a rare variation of a Bado type IV Monteggia-equivalent lesion (fracture of proximal ulnar shaft, proximal radial shaft, and radial head) and its management.

• Journal of Medicine and Life Science
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• v.20 no.3
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• pp.131-134
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• 2023

Here, we present a case of a 56-year-old man with acute myocardial infarction. The patient underwent percutaneous coronary intervention (PCI) at the left main bifurcation and mid-left anterior descending artery using drugeluting stents. Four months after the PCI, the patient was readmitted for cardiac arrest. Coronary angiography (CAG) revealed stent thrombosis in the left main-to-proximal left anterior descending artery and in-stent restenosis in the left main-to-proximal left circumflex artery. We performed balloon angioplasty at the left main to mid-left anterior descending artery and left main to proximal left circumflex artery stents; subsequently, blood flow was fully restored. However, contrast agent extravasation was observed outside the mid-portion of the left main artery to the proximal left anterior descending artery stent, indicating the presence of a coronary artery aneurysm (CAA) outside the stent. After guideline-directed medical therapy with dual antiplatelet agents and high-intensity statins, follow-up CAG revealed near-resolution of the CAA, absence of stenotic lesions, and good blood flow.

• Nonlinear Functional Analysis and Applications
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• v.29 no.1
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• pp.209-224
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• 2024

The goal of this study is to instigate various new and novel optimum proximity point theorems using the notion of implicit relation type ℶ-proximal contraction for non-self mappings. An illustrated example is used to demonstrate the validity of the obtained results. Furthermore, some uniqueness results for proximal contractions are also furnished with partial order and graph. Various well-known discoveries in the present state-of-the-art are enhanced, extended, unified, and generalized by our findings. As an application, we generate some fixed point results fulfilling a modified contraction and a graph contraction, using the profundity of the established results.