• 디지털융복합연구
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• 제11권2호
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• pp.205-214
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• 2013

애자일 개발방법론 기반의 소프트웨어 개발 프로젝트에서도 각광받고 있는 팀의 공동작업이 일반화되고 있다. 효율적인 팀워크는 보다 효과적인 팀 관리운영과 프로젝트의 성과 측면에서 매우 중요하다. 기존의 소프트웨어 개발 인력배치는 휴리스틱 방법을 사용하였지만 이를 보완하기 위한 알고리즘적 접근법도 필요하다. 본 논문에서는 팀워크 기반의 소프트웨어 개발 프로젝트에서 개발자의 인력 배치를 위한 수학적 접근 방안을 제안하였다. 제안한 방안은 6개의 프로세스로 구성되며, 각 프로세서에서의 활동을 수학적으로 정의하였고, 기능배치매트릭스를 사용하였다. 본 논문에서 제시한 접근방법의 유용성을 증명하기 위하여 사례 연구를 제시하였다. 본 논문은 그동안 직관적이나 경험적 방법으로 팀을 구성하는 방식에서 벗어나, 계량적인 논리에 의해 인적자원을 할당하는 수학적 접근방법을 개발하였다는데 큰 의의가 있다.

• 농업과학연구
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• 제43권5호
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• pp.742-749
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• 2016

Boar taint, an unpleasant odor of pork, is associated with two substances including androstenone and skatole. Testosterone is a steroid hormone as well as a strong predictor for androstenone secretion. Isoflavones of soy origin play a role in modulating the metabolism of sex hormones. Although several methods responsible for reducing boar taint are under investigation, the precise mechanism by which isoflavones reduce testosterone has not yet been identified. The objective of the current study was to investigate the effects of isoflavones extracted from a soy by-product on the concentration of serum testosterone in mouse. A total of 24 mice were supplemented with basal diet (control), daidzin plus genistin mix (T1), or isoflavone extracts (T2). After 11 days of treatment, size and weight of testis, as well as the concentration of sex hormones, including testosterone and estrogen, were analyzed. There was no difference in size or weight of testis from mice among control, T1, and T2. Serum testosterone levels were significantly decreased (p < 0.05) both in T1 and T2 when compared with the control group. Furthermore, estrogen concentration in blood was increased (p < 0.05) in T2 (numerically increased in T1) compared with the control group. Taken together, the use of isoflavones extracted from soy by-products would be a plausible strategy for reducing testosterone level, ultimately reducing boar taint without castration of piglets.

• 한국산업정보학회논문지
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• 제20권3호
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• pp.1-9
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• 2015

인터넷윤리는 대학에서 하나의 교양과목으로 위치하고 있으며, 본 연구자도 이 과목을 수년째 강의하고 있다. 인터넷윤리를 학생들에게 효과적으로 전달하기 위하여, 인터넷윤리 관련 동영상을 활용하고 일부 시범 실습을 실시하는 수업을 진행하였다. 최신 UCC 제시 및 이에 대한 토론도 진행하여 학생들의 인터넷윤리 이슈와 문제점을 인식시켰다. 그러나 단순히 비디오만 수동적으로 시청하는 것은 학생의 학습성과 향상 관점에서는 부족하다. 따라서 우리는 세 명이 팀을 이루어 인터넷윤리 주제에 관한 동영상을 제작하게 하였다. 이러한 팀프로젝트 교수법은 학생들이 수업에 능동적으로 참여하게 하고 스스로 비디오를 제작함으로써 개념을 이해하는데 효과적이다. 수강생 대상의 설문조사를 통하여, 제시된 UCC 제작 팀프로젝트 수업 방식이 학생들의 인터넷윤리 이해도 증진에 효과적임을 확인하였다.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2008년도 정기학술발표대회 논문집
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• pp.738-743
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• 2008

최근들어 BIM 기술은 건설프로젝트의 전 생애주기동안 생산성 향상을 위하여 활용되고 있는 바, 건설의 각 분야에서 적용함에 있어 프로젝트 별 (간섭체크용, 모델해석용, 공정 및 물량산출용, 공사현장용, 협업용 등) BIM 프로세스의 정립은 필수적 요소이다. 하지만 국내에서 프로젝트 별 BIM 프로세스가 정립되어 있는 사례 및 해당 연구는 아직 마련되어 있지 않은 실정이다. 본 연구에서는 건설사업 초기단계에서의 BIM 어플리케이션 설정 방법, BIM 팀구성 방법, 패밀리설정 방법, 모델링방법 연구를 통하여 BIM 프로세스 구축을 제안하고, Pilot Study 모델을 통한 기초설정 및 모델링 작업, 물량검토, 중립적인 포맷방식인 IFC $2{\times}3$ 버전을 활용한 정보교환 등을 실시하여 정립된 BIM 프로세스의 적용능력을 검토하여 국내 BIM 가이드라인 구축의 초석을 마련하고자한다.

• 대한예방한의학회지
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• 제4권2호
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• pp.93-107
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• 2000

Korea follows the Korea standard classification of disease and causes of death according to the ICD(international classification of disease) Oriental medicine began to of officially follow the classification of disease for using the Korean classification of diseases in 1972. The classification of OM(oriental medicine) has changed in shape experiencing two amendments. The largest difficulty was to overcome the different names of diseases between OM and ICD. A one-to-one correspondence of the name of a disease between OM and ICD is impossible So in the primary stage one-to-one and one-to-many correspondence was made. During the first amendment the international disease names were re-classified on the oriental medicine disease name's basis and at the same time the classification of OM was corresponded on a one-to-one basis to the ICD . During the second amendment this changed to many-to-many correspondence . Analyzing the history of classification of OM during the first and second amendments, it was discovered that establishment of the standards of classification, the unification of oriental medical terms, and overcoming the difference of disease names between the OM and ICD is necessary Also th classification and standardazation of OM must not stop as a single round. It must go on for a long time. The hosts of this project Korean oriental medical society and AKOM(association of korean oriental medicine) need to build a independant department which will supervise the classification project and monitor any problems to come up. Also a route through which suggestions can be taken in and new solutions can be brought up needs to be secured and an atmosphere in which studies can take place about the basis of classifications needs to be developed.

• Toxicological Research
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• 제23권2호
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• pp.135-142
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• 2007

Formononetin is an isoflavonoid phytoestrogen found in certain foodstuffs such as soy and red clover. In this study, we examined the action of formononetin with the carcinogen activation pathway mediated through the aryl hydrocarbon receptor (AhR) in MCF-7 breast carcinoma cells. Treating the cells with formononetin alone caused the accumulation of CYP1A1 mRNA as well as elevation in CYP1A1-specific 7-ethoxyresorufin O-deethylase (EROD) activity in a dose dependent manner. However, a concomitant treatment with 7,12-dimethylbenz[a]anthracene (DMBA) and formononetin markedly reduced both the DMBA-inducible EROD activity and CYP1A1 mRNA level. Under the same conditions, formononetin inhibited the DMBA-induced AhR transactivation, as shown by reporter gene analysis using a xenobiotic responsive element (XRE). Additionally, formononetin inhibited both DMBA-inducible nuclear localization of the aryl hydrocarbon receptor (AhR) and metabolic activation of DMBA, as measured by the formation of the DMBA-DNA adducts. Furthermore, formononetin competed with the prototypical AhR ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), for binding to the AhR in an isolated rat cytosol. These results suggest that formononetin might be considered as a natural ligand to bind on AhR and consequently produces a potent protective effect against DMBA-induced genotoxicity. Therefore, that's the potential to act as a chemopreventive agent that is related to its effect on AhR pathway as antagonist/agonist.

• 경영정보학연구
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• 제11권2호
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• pp.113-129
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• 2009

정보보호 분야에 대한 관심이 증가하면서 정보보호 인력 양성에 대한 연구가 다각도로 진행되어 왔다. 현재 정보보호는 그 적용 분야가 광범위해짐에 따라 정보보호 인력이 수행하는 업무 범위도 증가하고 있어 보다 효율적인 인력의 양성 및 관리를 위한 노력이 필요하다. 이를 위해서는 정보보호 전문인력이 직무수행시 필요로 하는 전문 지식 및 기술을 분석하여 교육 프로그램 개발 및 운영에 반영해야 할 것이다. 본 연구에서는 문헌고찰 및 델파이 방법을 통해 정보보호 분야의 58개 지식 및 기술을 도출하고 산업체와 교육기관에 종사중인 정보보호 전문인력을 대상으로 각 자식 및 기술에 대한 필요정도 및 숙련정도를 조사하였다. 이와 함께 두 분야 전문인력의 정보보호 지식 및 기술에 대한 인식의 차이를 비교 분석하였다. 본 연구의 결과는 정보보호 신규인력을 배출하는 교육기관과 신규인력에 대한 수요처인 산업체 간 인식의 격차를 최소화하고 상대적으로 산엽 현장에서 요구하는 지식 및 기술을 중심으로 한 교육 프로그램의 개발과 운영을 위해 활용될 수 있을 것으로 기대된다.

• 천문학회보
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• 제36권2호
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• pp.126.1-126.1
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• 2011

The SPICA (SPace Infrared Telescope for Cosmology & Astrophysics) project is a next-generation infrared space telescope optimized for mid- and far-infrared observation with a cryogenically cooled 3m-class telescope. Owing to unique capability of focal plane instruments onboard SPICA, it will enable us to resolve many astronomical key issues from the star-formation history of the universe to the planetary formation. The FPC (Focal Plane Camera) is a Korean-led near-infrared instrument as an international collaboration. Korean consortium for FPC proposed a key instrument responsible for a fine guiding (FPC-G). The back-up of FPC-G will make scientific observations as well. We have examined the legacy science programs for FPC and performed the feasibility study for the fine guiding system. Recently, the international review process is now in progress, in order to make a selection of the focal plane instruments. Here, we report the current status of SPICA/FPC project.

• The Korean Journal of Physiology and Pharmacology
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• 제21권6호
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• pp.567-577
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• 2017

Obesity is known to induce inhibition of glucose uptake, reduction of lipid metabolism, and progressive loss of skeletal muscle function, which are all associated with mitochondrial dysfunction in skeletal muscle. Mitochondria are dynamic organelles that regulate cellular metabolism and bioenergetics, including ATP production via oxidative phosphorylation. Due to these critical roles of mitochondria, mitochondrial dysfunction results in various diseases such as obesity and type 2 diabetes. Obesity is associated with impairment of mitochondrial function (e.g., decrease in $O_2$ respiration and increase in oxidative stress) in skeletal muscle. The balance between mitochondrial fusion and fission is critical to maintain mitochondrial homeostasis in skeletal muscle. Obesity impairs mitochondrial dynamics, leading to an unbalance between fusion and fission by favorably shifting fission or reducing fusion proteins. Mitophagy is the catabolic process of damaged or unnecessary mitochondria. Obesity reduces mitochondrial biogenesis in skeletal muscle and increases accumulation of dysfunctional cellular organelles, suggesting that mitophagy does not work properly in obesity. Mitochondrial dysfunction and oxidative stress are reported to trigger apoptosis, and mitochondrial apoptosis is induced by obesity in skeletal muscle. It is well known that exercise is the most effective intervention to protect against obesity. Although the cellular and molecular mechanisms by which exercise protects against obesity-induced mitochondrial dysfunction in skeletal muscle are not clearly elucidated, exercise training attenuates mitochondrial dysfunction, allows mitochondria to maintain the balance between mitochondrial dynamics and mitophagy, and reduces apoptotic signaling in obese skeletal muscle.

• 대한인간공학회지
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• 제30권5호
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• pp.659-669
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• 2011

Objective: The aim of this study is to suggest a package layout guideline for low-floor bus by interview with passengers and observations of their behavior. Background: Increasing attention has been introduced the low-floor bus to be more suitable for use by transportation handicapped. Complex issues are involved in providing comfortable services to all people. We are going to suggest package layout guidelines for more comfortable and suitable travel to all people. Method: The two times of survey and video observation sessions were conducted on low-floor buses in Seoul; (1) a finding of potential issues in the first session, (2) a confirming of issues from the last session. Results: The three of major issues were founded in this study; (1) difficulties in supporting body when standing, (2) difficulties in sitting on front wheel pan seat, (3) difficulties in passing through the aisle. Conclusion: There were clear differences between public and transportation handicapped in using some tools which are used for support body such as roof hand rails, side hand rails, and hand rail rings. Some of design problems were founded to improve from the perspective of ergonomics and universal design. Such differences and design guidelines have to be considered in bus design as well as commercial vehicle. Application: The proposed design guidelines can be used to development of low-floor bus and other public transportations.