• 벤처창업연구
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• 제7권1호
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• pp.225-232
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• 2012

벤처중소기업들은 초기 사업화 과정에서 신생기업의 위험 문제로 어려움을 겪고 있는데, 공공부문을 포함한 외부 인큐베이터의 지원은 벤처중소기업들의 애로요인 극복에 도움이 될 수도 있다. 이와 관련하여 국가연구개발기관에서 수행 중인 기술사업화 종합지원사업의 의의와 필요성을 검토하고, 구체적인 사례로서 한국세라믹기술원의 세라믹히든챔피언 종합육성사업을 분석하였다. 국가연구개발기관의 기술사업화 종합지원사업은 국가연구개발사업의 사업화 성과 향상 뿐 아니라 영세한 기업의 자원보완 및 지식 전수라는 점에서 긍정적으로 검토해볼 필요가 있을 것으로 판단된다. 그러나, 사례조사 결과 외부지원기관 및 지원기업에 대한 유인체계 및 관리시스템의 개선, 추진조직 활동 간의 조정문제 등은 해결해야 할 과제로 보인다.

• Applied Microscopy
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• 제36권2호
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• pp.83-91
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• 2006

신경연접은 다양한 생리적 또는 병적 상태에 반응하여 구조 및 수적 변화를 보이며, 신경연접의 밀도 변화는 신경세포의 활성 조절에 중요한 역할을 하는 것으로 알려져 있다. 따라서 특정 생리적 또는 병적 상태에서 신경연접의 밀도 변화를 명확히 이해하기 위해서는 정확한 정량방법을 이용한 밀도 측정이 필수적이다. 본 연구에서는 physical disector법을 이용하여 흰쥐 뇌의 치아이랑에 위치하는 과립신경세포의 신경연접 수를 측정하였으며, 이를 통해 physical disector의 방법적 정확성을 확인하고자 하였다. 성체 흰쥐를 관류고정한 후 치아이랑의 연속 절편을 얻어 통상적인 전자현미경 시료제작법을 통해 Epon 혼합용액에 포매하였다. Physical disector법을 이용한 밀도 분석 시 연속절편의 정렬, 비교 및 disector frame이 필요하므로 Reconstruct 프로그램을 사용하였다. 동물 당 40장의 $1{\mu}m$ 연속절편을 제작하여 과립신경세포체의 밀도를 측정하였으며, 15장의 80nm연속절편으로부터 bidirectional disector법을 이용하여 과립신경세포와 내측 관통로(medial perforant path) 간 신경 연접의 밀도를 분석하였다. 과립신경세포의 세포체와 신경연접은 각각 과립층과 분자층에 위치하기 때문에 하나의 신경세포가 가지는 신경연접의 수를 측정하기 위해서는 각 층의 부피를 고려하는 것이 요구된다. 따라서 과립층에 대한 분자층의 부피비율을 측정하였다. 실험결과, 흰쥐 치아이랑에 위치하는 하나의 과립세포당 약 6,500개의 신경연접의 존재한다는 사실을 확인하였으며, 이는 다른 연구자들의 결과와 유사하였다. 본 연구로부터 physical disector법은 특정 생리적 또는 병적 조건에서 나타나는 신경세포 및 신경연접의 수적 변화를 정확히 측정할 수 있는 유용한 정량방법임을 알 수 있었다. 향후 physical disector법을 이용하여 다양한 실험동물모델의 신경연접 변화를 분석하는 것은 신경연접의 형태적 가소성을 이해하는데 이바지할 것으로 생각된다.

• 한국조경학회지
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• 제30권2호
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• pp.70-78
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• 2002

The landscape disign of Gamcheon wholesale fish Market was designed around a turnkey base to promote the economy of Busan Metropolitan City, to establish a fishery marketing center and to modernize existing facilities. The objectives of the project were to promote the mood of an old market, while preserving its functions and efficiency as a market, to design outdoor spaces with natural resources and amenities in balance, and to create attractive tourist spots in connection with the wide area development plan. The project was oriented, fast, to enhance the functions of the market. For this purpose, a multi-dimensional space layout was designed in consideration of functions as a wholesale market. The safety of pedestrians was secured by separating lathes for vehicles and for pedestrians. Tree planting with various functions such as sheltering, wind breaking and guiding was planned. Secondly, nature-friendly and human-friendly landscaping design was attempted. For this, the beautiful natural resources of Amnam Park were utilized, and green spaces such as green bridges linking buildings in the wholesale market, and rooftop gardens were to be arranged. In addition, environment-friendly facilities such as roads paved with natural materials(i.e. gravel, shells) and program parking lots were to be planned. Thirdly, landscape design was considered to create attractive tourist spots. For example, a fish farm was created as a theme street for pedestrians and various water-friendly spaces such as pedestrian ramps, observatories and seaside streets were to be secured. The main contents are as follows. First, a green bridge to Ahnnam Park was introduced for a tour source and flower garden, an event plan and viewing deck open to the sea were planned on the bridge's axis. Secondly, for the effective land use plan concerning open space and convenience to visitors, a promenade was planned, which is connected with the theme plaza and small plazas by environmental sculptures in front of the market hall and at the gate. As well, an observatory and a roof garden help create three dimensional multi leveled space, with a good view of the natural landscape of the sea, sky and park Thirdly, landscape materials, such as trees and those for facilities, strengthened for protection against the seawind and salt damage were selected. The commercial market area was intended to be transformed a traditional functional area of efficiency and economy into an attractive marine leisure area where both tourists and neighbors can make use of it.

• 한국보건간호학회지
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• 제12권2호
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• pp.1-11
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• 1998

This study was performed to analyze the occupational health nursing of support-project of health management skill for small-scale industries. The 2 subject centers were under the umbrella of Korean Industrial Health Association and data collection period was 2weeks from September 1 to 13. 1997 and time and motion study method was used. Data was handled by SPSS win 7.5 program. results were worked out number. percentage. F-value. (1) The weekly time spending of occupational health nurses was distributed into indoor service 46.9%, outdoor service 26.6%, movement 26.5%. The mean visiting times were 2-3 times per week. and spending time was about 1 hour per industry. (2) There are statistically significant difference among the distribution of time spending according to industrial works(F=23.08. p=.000). and the special education for occupational disease prevention takes the most mean time. (3) There were statistically significant difference among the spending time for the health coach of occupational health nurses(F=188.79. p=.000). and the activity time for workers (58.4%) was more than that of for monitors(41.6%). The frequency of health coachs were 155 times for monitors during two weeks. but health coach for worker was 87 times. As a results. the contents of health coach for workers was proved to take more time than that for monitors. Perhaps we think that monitors has limitation for health management. therefore we should be consider flexible management of visiting time and health coach guidelines for occupational health nurses. (4) There were statistically significant differences among the distribution of time spending according to health coach methods for industrial health nurses(F=66.31. p=.000). The most frequent method of all was guide transmission. 159 times(65.7%), and the mean spending time for instruction was 19.78 min. the longest time. Our suggestion for occupational health nursing of support-project of health management skill for small-scale industry is that the need of each industry is very complex because of various conditions. therefore need assessment for industries should be conducted professionally. And occupational health nurses should apply occupational health nursing process autonomously. and their activities be guaranted by the guideline

• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2005년도 추계학술대회 및 한일 식물생명공학 심포지엄
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• pp.95-105
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• 2005

Transposon-mediated insertional mutagenesis provides one of the most powerful tools for functional studies of genes in higher plants. This project has been performed to develop a large population of insertional mutations, and to construct databases of molecular information on Ds insertion sites in rice. Ultimate goals are to supply genetic materials and information to analyze gene function and to identify and utilize agronomically important genes for breeding purpose. Two strategies have been employed to generate the large scale of transposon population in a Japonica type rice, Dongjin Byeo; 1) genetic crosses between Ac and Ds lines and 2) plant regeneration from seeds carrying Ac and Ds. Our study showed that over 70% of regenerated plants generally carried independent Ds elements and high activity of transposition was detected only during regeneration period. Ds-flanking DNA amplified from leaf tissues of F2 and T1 (or T2) plants have been amplified via TAIL-PCR and directly sequenced. So far, over 65,000 Ds lines have been generated and over 9,500 Ds loci have been mapped on chromosomes by sequence analysis. Database of molecular information on Ds insertion sites has been constructed, and has been opened to the public and will be updated soon at http://www.niab.go.kr. Detailed functional analysis of more than 30 rice mutants has been performed. Several Ds-tagged rice genes that have been selected for functional analysis will be briefly introduced. We expect that a great deal of information and genetic resources of Ds lines would be obtained during the course of this project, which will be shared with domestic and international rice researchers. In addition to the Japonica rice, we have established the tagging system in an rice line of indica genetic background, MGRI079. MGRI079 (Indica/Japonica) was transformed with Agrobacteria carrying Ac and Ds T-DNA vectors. Among transgenic lines, we successfully identified single-copy Ds and Ac lines in MGR1079. These lines were served as ‘starter lines’ to mutagenize Indica genetic background. To achieve rapid, large scale generation of Ds transposant lines, MGR1079 transformants carrying homozygous Ac were crossed with ones with homozygous Ds, and $F_2$seeds were used for plant regeneration. In this year, over 2,000 regeneration plants were grown in the field. We are able to evaluate the tagging efficiency in the Indica genetic background in the fall.

• The Korean Journal of Pain
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• 제20권2호
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• pp.100-105
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• 2007

Background: Ginseng has been used to manage various types of pain in folk medicine. This study characterized the effect of treatment with intrathecal ginsenosides, the active components of ginseng in a postoperative pain model. Methods: Male Sprague-Dawley rats were implanted with lumbar intrathecal catheters. An incision was made in the plantar surface of the hindpaw. Withdrawal thresholds following the application of a von Frey filament to the wound site were measured. To determine the role of the opioid or GABA receptors following treatment with the ginsenosides, naloxone, bicuculline (a $GABA_A$ receptor antagonist), and saclofen (a $GABA_B$ receptor antagonist) were administered intrathecally 10 min before the delivery of the ginsenosides and the changes of the withdrawal thresholds after application of the von Frey filament were Observed. Results: Treatment with the intrathecal ginsenosides increased the withdrawal threshold in a dose dependent manner. Pre-treatment with intrathecal naloxone reversed the antinociceptive effect of the ginsenosides. However, pre-treatment with intrathecal bicuculline and saclofen failed to have an effect on the activity of the ginsenosides. Conclusions: These results suggest that ginsenosides are effective to alleviate the postoperative pain evoked by paw incision. The opioid receptor, but not GABA receptors, may be involved in the antinociceptive action of the ginsenosides at the spinal level.

• 농촌계획
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• 제25권4호
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• pp.77-86
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• 2019

The purpose of this study is to survey and analyze the operating state and characteristics of domestic and foreign green care, prioritize the facilities and programs for green care introduction through expert survey of importance, and thereby to provide a basic material for introducing green care in facilities in Rural Development Project districts, including domestic rural experience facilities. Domestic and foreign literature was analyzed in order to classify the necessary facilities programs, of green care, and the analysis results were modified and supplemented through Expert Delphi Survey. Based on the results, AHP based importance survey was conducted. In terms of the facilities and programs for green care introduction, necessary facilities (H/W) were categorized into four types (accommodation facility, resting facility, experience facility, therapy facility) and S/W programs into three types (learning experience type, therapy type, and care type). To verify the reliability of the AHP based importance survey, Consistency Index (C.I.) was analyzed. As a result, the C.I. value of nine respondents ranged from 0.000 to 0.083 so that the survey was found to have high consistency. The importance of S/W programs was 0.627, and that of H/W facilities was 0.373. For green care introduction, programs were found to be more important. Regarding the categories of necessary facilities, therapy facility had the highest value, or 0.348; experience facility 0.253; accommodation facility 0.211; resting facility 0.188. Therefore, therapy facility and experience facility were found to be important. In case of S/W programs, therapy type had the highest value, or 0.499, and learning experience type (0.255) and care type (0.246) were similarly important. Generally, the categories that had high importance values tended to show a remarkable difference in importance of their sub categories. In particular, facilities or therapy programs using natural ecology and forests were found to be highly important. In conclusion, it is required to actively review the introduction of active programs using resources, such as existing experience facilities and accommodation facilities and villages forests, and programs making the body and soul comfortable, such as natural ecology experience, Green Shower, and horticulture activity.

• 한국사회복지학
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• 제51권
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• pp.257-286
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• 2002

이 연구는 주민조직화 활성화 방안의 하나로 지역주민대표자 리더십 교육 훈련 프로그램을 개발하기 위한 것이다. 최근 사회복지실천에서는 "지역사회"를 배경으로 한 실천방법의 중요성이 크게 강조되고 있으며 이에 따라 주민들의 역량강화(empowerment)를 위한 지역사회조직의 필요성이 커지고 있다. 그러나 현장에서 일하고 있는 다수의 사회복지사들은 지역사회조직화에 대한 필요성이 커지고 있다. 특히 사회복지관이 다수 위치하고 있는 도시영구임대주택지역에서는 지역사회조직사업이 더욱 어려운 실정이다. 그 이유 중 하나로 소수의 사례이기는 하나 도시영구임대주택지역에서 활동하고 있는 하위조직의 운영절차가 비민주적이며, 불투명하고 비개방적인 특성을 보이고 있는 점을 들 수 있다. 이 연구에서는 주민조직의 이러한 특성을 극복하고 효과적으로 지역사회조직사업을 실천하기 위한 방안으로 지역주민대표자의 리더십을 강화하는 프로그램을 개발하고자 하였다. 실천방법은 진행단계를 크게 "일반조직화"와 "복지조직화"로 구분하여 소집단 중심의 교육, 훈련방법을 택하였으며 프로그램의 기획, 실천의 전 과정을 질적평가방법으로 분석하였다. 본 연구의 의의는 예비대상자 모집, 프로그램기획, 지역사회조직화사업 단계별 활동방법, 자조집단(self-help) 구성 등에 대한 구체적 실천방법을 제안하고 있다는 점을 들 수 있다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2016년도 학술발표회
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• pp.189-189
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• 2016

To generate information that contributes to climate change risk management, it is important to perform a precise assessment on the impact in diverse aspects. Considering this academic necessity, Japanese government launched continuous research project for the climate change impact assessment, and one of the representative project is Program for Risk Information on Climate Change (Sousei Program), Theme D; Precise Impact Assessment on Climate Change (FY2012 ~ FY2016). In this research program, quantitative impact assessments have been doing from a variety of perspectives including natural hazards, water resources, and ecosystems and biodiversity. Especially for the natural hazards aspect, a comprehensive impact assessment has been carried out with the worst-case scenario of typhoons, which cause the most serious weather-related damage in Japan, concerning the frequency and scale of the typhoons as well as accompanying disasters by heavy rainfall, strong winds, high tides, high waves, and landslides. In this presentation, a framework of comprehensive impact assessment with the worst-case scenario under the climate change condition is introduced based on a case study of Theme D in Sousei program There are approx. 25 typhoons annually and around 10 of those approach or make landfall in Japan. The number of typhoons may not change increase in the future, but it is known that a small alteration in the path of a typhoon can have an extremely large impact on the amount of rain and wind Japan receives, and as a result, cause immense damage. Specifically, it is important to assess the impact of a complex disaster including precipitation, strong winds, river overflows, and high tide inundation, simulating how different the damage of Isewan Typhoon (T5915) in 1959 would have been if the typhoon had taken a different path, or how powerful or how much damage it would cause if Isewan Typhoon occurs again in the future when the sea surface water temperature has risen due to climate changes (Pseudo global warming experiment). The research group also predict and assess how the frequency of "100-years return period" disasters and worst-case damage will change in the coming century. As a final goal in this research activity, the natural disaster impact assessment will extend not only Japan but also major rivers in Southeast Asia, with a special focus on floods and inundations.

• 디지털융복합연구
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• 제17권10호
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• pp.209-221
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• 2019

혁신적인 제품을 개발하는 과정에서 성과를 내기 위해서는 전문성을 갖춘 부품 공급업체와의 협력이 필요하다. 또한 개발 참여자의 개인역량을 키우고 지식을 공유하는 것이 중요하다. 본 연구는 참여자의 직무역량과 리더십역량이 지식공유에 미치는 영향과, 구매업체의 상호의존성이 공급업체 흡수역량에 미치는 영향을 실증적으로 분석하였다. 연구목적은 개발참여자와 공급업체의 지식공유가 성과에 기여함을 확인하고, 공급업체와의 협력적 관계의 필요성을 증명하기 위함이다. 제품개발 참여자들을 대상으로 설문조사를 실시하여 각 요인간의 관계를 구조방정식 모형으로 확인하였다. 가설검증 결과, 개발 참여자들의 개인역량이 뛰어날수록 지식공유 활동을 향상시키며, 지식공유와 상호의존성은 공급업체 흡수역량에 주요한 요인임을 확인할 수 있었다. 본 연구결과는 첨단기술이 융복합되는 제품개발 프로젝트에서, 성과 향상에 필요한 공급업체의 흡수역량을 제고하는데 기여할 수 있을 것이다. 향후에는 성과를 위한 사내 관련부서의 프로젝트 지원활동 효과에 대해 연구하고자 한다.