• Genomics & Informatics
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• v.20 no.1
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• pp.9.1-9.6
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• 2022

Mendelian randomization (MR) uses genetic variation as a natural experiment to investigate the causal effects of modifiable risk factors (exposures) on outcomes. Two-sample Mendelian randomization (2SMR) is widely used to measure causal effects between exposures and outcomes via genome-wide association studies. 2SMR can increase statistical power by utilizing summary statistics from large consortia such as the UK Biobank. However, the first-order term approximation of standard error is commonly used when applying 2SMR. This approximation can underestimate the variance of causal effects in MR, which can lead to an increased false-positive rate. An alternative is to use the second-order approximation of the standard error, which can considerably correct for the deviation of the first-order approximation. In this study, we simulated MR to show the degree to which the first-order approximation underestimates the variance. We show that depending on the specific situation, the first-order approximation can underestimate the variance almost by half when compared to the true variance, whereas the second-order approximation is robust and accurate.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2009.04a
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• pp.264-264
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• 2009

• Journal of Families and Better Life
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• v.14 no.2
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• pp.77-96
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• 1996

The purposes of this study were to understand caregiving situation and to develop education program for families with the demented elderly,. Family caregivers of elderly patients with dementia clearly experience high levels of stress which often leads to such negative caregiver outcomes as depression interference with social activities and health difficulties. That is providing care is stressful for caregivers because the demands of the caregiving situation threaten to overwhelm the caregivers' coping resources. Therfore the families with demented elderly persons need assistances in order to alleviated burden of caregiving, In this study the educational program was designed to increase caregivers' confidence in problem-solving, And it was designed to provided information to demented elderly. The educational program of this study was given 5 session. And it was included the understanding of dementia the family caregiving experiences of the demented elderly persons the time for elf-care the search for helping the improving of interpersonal relations and communications.

• International Journal of Contents
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• v.15 no.3
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• pp.39-46
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• 2019

This study aimed to develop a peer-assisted learning (PAL) program for use in a core nursing skills education course and to investigate the effects of the education program on three key outcomes. A comparative study was conducted through the division of students of a core nursing skills education program into a treatment group and control group. After the programs, self-efficacy, confidence and satisfaction were compared between the groups. The comparison of these three factors indicated that the related scores were significantly higher in the treatment group receiving the education program with the PAL method than those of the control group receiving traditional education. We concluded that self-efficacy gave the nursing students the confidence that they could successfully perform their tasks and motivation to learn. Education programs using the PAL method are suggested as an effective method for the acquisition of skills among nursing students.

• The Journal of Korean Association of Computer Education
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• v.17 no.2
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• pp.53-64
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• 2014

The purpose of the study is to develop a scale for measuring learning outcomes in the distance teacher training programs. In order to develop the measurement instrument, the forty-four items were developed based on the literature review and ten experts' review. For data collection, a web-based survey was conducted among teachers taking a distance teacher training program at National Education Training Institute. With the data of 205 sample size from the first survey, the Exploratory Factor Analysis was conducted and seven factors were identified. In order to validate the test, the Confirmatory Factor Analysis was performed with 293 respondents from the second survey. In conclusion, this study reports the reliability and validity of a scale for learning outcomes in distance teacher training programs consisting of seven factors with 34 items; 1) system quality, 2) content quality, 3) service quality, 4) use, 5) benefit, 6) satisfaction, 7) transfer.

• Journal of the Korean Society of Physical Medicine
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• v.12 no.4
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• pp.73-82
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• 2017

PURPOSE: Proprioceptive Neuromuscular Facilitation (PNF) has been shown to improve body function and activity/participation in people with functional dysfunctions. This study evaluates if active exercise using theraband in PNF pattern may induce similar benefits as exercise using manual PNF pattern performed by physiotherapists on promoting mobility, balance and fear of fall in community-dwelling elderly. METHODS: Twenty-three community-dwelling elderly with independent activities of daily living were recruited and randomly allocated into either PNF group - exercise in PNF pattern by trained physiotherapists or Theraband-PNF (T-PNF) group - exercise using theraband in PNF pattern, for an hour, twice weekly for 4 weeks. Functional outcomes such as Timed Up and Go test, Elderly Mobility Scale, Berg balance scale, functional reach and subjective measures including fear of fall (FOF) scale, bodily pain in visual analogue scale were measured pre and post-program. RESULTS: Twenty-one participants completed the program. PNF group demonstrated significant within-group improvements in all subjective measures and objective measures. Similar within-group improvements were demonstrated in all outcome measures except FOFS in T-PNF group. However, no between-group differences were found in any of the outcome measures. CONCLUSION: Comparable improvements in functional outcomes in community dwelling elderly were demonstrated in both groups. As manual PNF exercise traditionally need clinicians' contact and feedback on patient which limit the training to be carried out extensively in community setting. The current findings suggest that exercise using theraband in PNF pattern is feasible to be adopted as self-practice exercise for community-dwelling elderly to induce beneficial effects on functional outcomes.

• The Journal of the Korea Contents Association
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• v.17 no.12
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• pp.330-338
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• 2017

The purpose of this study is to examine the effect of blended learning approach on academic achievement and self directed learning skills of nursing undergraduate students. This experimental study is designed for a nonequivalent control group. The number of subjects in this research consists of 145, where 75 of the experimental group participated in blended learning program and 70 of the control group didn't do. The data was analyzed by $x^2$-test, Fisher's exact test, t-test and paired t-test. The effects of blended learning approach on learning outcomes in women's health nursing are as follows : The academic achievement of the experimental group has been more elevated than that of the control group on final examination. The experimental group has made increase in self directed learning skills. The blended learning approach on learning outcomes in nursing major are effective. This study has significant implication in that it identified the availability of the blended learning program and that it would be a useful teaching and learning method to achieve learning outcomes.

• YAKHAK HOEJI
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• v.58 no.2
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• pp.129-140
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• 2014

Background: As elderly population has been increasing, pharmacists need to possess special knowledge and skills to provide enhanced pharmaceutical care for senior patients. Purpose: This study aims to systematically review on (1) the certified geriatric pharmacists (CGP) system, (2) the curriculum related to geriatric pharmacy education, and (3) the CGP's performance in terms of clinical, economic and humanistic outcomes in the U.S. Method: The information related to CGP system and curriculum was obtained through the official websites of 'American Society of Consultant Pharmacists', 'Commission for Certification in Geriatric Pharmacy' and the selected pharmacy school samples. Articles about on the outcomes of pharmacist-provided cognitive services including Medication Therapy Management were searched through PubMed. Results: To gain the CGP credential, pharmacists need 2-year experience as pharmacist in advance and take the CGP examination. This certification must be renewed every 5 year. Most pharmacy schools provide geriatric-related curriculum through didactic or pharmacy practice classes for pharmacy students and certificate or dual degree in gerontology are given on completion. Most previous outcomes research reported that pharmacists have played a role in yielding favorable results regarding clinical, economic and humanistic outcomes for nursing facilities, hospitals and community pharmacy settings. Conclusion: Considering the organized CGP certification system and concrete educational courses established the basis for pharmacists to exert their ability for senior patients of the U.S., it is suggested to build a geriatric pharmacist credential model for pharmacists to provide the increasing elderly patients with the requisite safe and effective pharmacy care in Korea.

• Journal of The Korean Association For Science Education
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• v.33 no.3
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• pp.626-638
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• 2013

The purpose of this study was to design a development frame for multicultural science program and develop a corresponding program using the frame. This study organized a development frame to design a multicultural science education program based on the culturally responsive teaching theory. This development frame consisted of the elements of purpose, teaching examples, teaching and learning methods, and assessment. This program consisted of the guideline for class teaching courses, reading materials, student worksheet, and teachers' reference materials. Based on this development frame, a multicultural science education program was developed, which was comprised of seven activities for elementary and middle school students. Each activity of the program included the concept and inquiry related to science education. In particular, by connecting the concept of science with the cultural characteristics of various countries, the activity made students aware of cultural diversity and the commonness of science principles. Compared to other subjects, the science education field has not actively undertaken studies on multicultural education. In term of dealing with universal principles, science education is suitable for making students aware of commonness. Accordingly, this gives rise to the need to draw cultural characteristics based on basic studies such as the analysis of science textbooks in various countries and develop culturally responsive programs utilizing the outcomes.

• Journal of Korean Academy of Nursing
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• v.43 no.2
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• pp.236-246
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• 2013

Purpose: This study was done to develop a measurement tool for evaluation of continuing nursing education programs and to verify its validity for effective management and quality of education programs. Methods: The draft of the evaluation measurement was developed from consultation with professionals, focus group interviews targeting groups of nurses, and individual interviews with education program planners. After 6 professionals examined content validity, 46 items were retained. A pilotsurvey was conducted to confirm the time required to complete the questionnaire and the level of understanding of general content and each item in the questionnaire. Construct validity was verified through exploratory factor analysis of data from a survey with 44 items completed by 452 nurses and 59 education program planners. Results: The final evaluation measurement for continuing nursing education programs consisted of 6 evaluation factors and 36 evaluation items. The 6 evaluation factors included identifying program goals and target groups, program planning, performance, operation and management, program outcomes, and program effectiveness. Conclusion: The evaluation measurement for continuing nursing education programs developed in this study is considered suitable to utilize as an evaluation measurement of the quality of continuing education programs for nurses.