• Title/Summary/Keyword: productivity of IL-2

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Primary Productivity of Phytoplankton in the Shallow and Hypertrophic River (Seonakdong River) (서낙동강에서 식물플랑크톤의 1차 생산성)

  • Jeon, Seung-Il;Cho, Kyung-Je
    • Korean Journal of Ecology and Environment
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    • v.37 no.1 s.106
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    • pp.57-63
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    • 2004
  • Primary productivity of phytoplankton was measured by $^{14}C$ method from January to October of 1996 in Seonakdong River. This river was a highly productive freshwater showing the euphotic depth of 1.4 m in August and 2.1 m in the remaining season. Chlorophyll-a concentrations of phytoplankton ranged from 67 ${\mu}g\;L^{-1}$ to 894 ${\mu}g\;L^{-1}$ and showed the great increase in August. Maximum specific productivity was 2.1 ${\sim}$4.3 mg C mg $chl-a{-1}\;hr^{-1}$ and occurred above 0.4m depth. In photosynthesis-irradiance relation, photoinhibition or photosynthetic suppression of phytoplankton occurred clearly in the cold seasons, while phytoplankton (mainly Microcystis aeruginosa and its relatives) in August did not show any symptom of the photosynthetic inhibition against the high irradiance. The specific productivity of phytoplankton was eventually dependant upon incident irradiance to show the linear correlation with received irradiance infield, and the areal productivity of phytoplankton upon chlorophyll-a standing crops. In the downstream of the Nakdong River, phytoplankton productions have linearly increased since the estuarine barrage construction to reflect the gradual eutrophication in the estuarine area. Average chlorophyll-a increase of 10 ${\mu}g\;chl-a\;L{-1}$ absolutely corresponded to the primary production acceleration of 30 mg C $m^{-2}\;day^{-1}$ on the annual basis.

Media Optimization for the Production of Aminopeptidase M Inhibitors MR-387A and B by Streptomyces sp. SL-387 (Streptomyces sp. SL-387에 의한 Aminopeptidase M 저해제 MR-387A 및 B의 생산 배지 최적화)

  • Chung, Myung-Chul;Chun, Hyo-Kon;Lee, Ho-Jae;Lee, Choong-Hwan;Kim, Su-Il;Kho, Yung-Hee
    • Applied Biological Chemistry
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    • v.38 no.2
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    • pp.100-105
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    • 1995
  • Media optimization for the production of MR-387A and B, novel aminopeptidase M inhibitors by Streptomyces sp. SL-387 isolated from a soil was studied. Optimized medium was consisted of 1% glucose, 3% soybean meal, 0.2% yeast extract, 0.1% beef extract, 0.3% NaCl, 0.01% $K_2HPO_4$, 0.3% $CaCO_3$, 0.001% $MnCl_2{\cdot}4H_2O$, 0.001% $ZnCl_2{\cdot}7H_2O$, and 0.0005% $MgSO_4{\cdot}7H_2O$, and adjusted to pH 7.0 before autoclaving. When the optimized medium was used as a fermentation medium, maximum productivity of MR-387 was reached at 120 hours of fermentation, and total productivity was 909.1 U/ml.

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Production of Newcastle vaccine using continuous mammalian cells

  • Gwak, Il-Yeong;Choe, Yeon-Suk;Jeong, Yeon-Ho;Jeon, Gye-Taek;Kim, Ik-Hwan
    • 한국생물공학회:학술대회논문집
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    • 2002.04a
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    • pp.281-284
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    • 2002
  • Specific pathogen free (SPF) eggs have been used to produce live vaccines. however, their application causes many problems such as cost, space and waste disposal. The substitution of mammalian cells for SPF eggs offers a desirable system of vaccine production. In this study, mammalian cells were tested for the infection of Newcastle disease virus (NDV). As a result, DF-I and MDBK cells showed high virus productivity compared to the other mammalian cells. For the highest productivity of NDV, the optimal multiplicity of infection (M.O.I.) in DF-I or MDBK cells was determined to be 0.2 or 0.5 M.O.I., respectively.

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Immunostimulating Effect of Goamshimshinhwan on Methotrexate-induced Immunosuppressed SD Rats (고암심신환(古庵心腎丸)이 methotrexate로 유발된 SD Rat의 면역기능저하에 미치는 영향)

  • Kang, Dae-Sung;Kwon, Eun-Hee;Lee, Yeon-Kyeong;Shin, Hyeon-Cheol;Kang, Seok-Bong;Park, Song-Kee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.6
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    • pp.1576-1583
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    • 2006
  • In order to investigate the effect of Goamshimshinhwan(GASSW) on SD rats with deteriorated immunity caused by methotrexate. Methotrexate was fed to the SD rats once a day for 4 days. After the immune responses of the at a dosage 1,000, 500 and 250mg/kg/10ml. and the changes on body weight and gains, spleen weight, total blood leukocyte numbers, total lymphocyte numbers, the percentage of B-cell, T-cell, CD3+CD+4 T-cell, CD3+CD8+ T-cell and CD4+/CD8+ T-cell ratios in the bolld and spleen were observed. In addition, the serum IL-2 levels and productivity of IL-2 of splenic cells were also demonstrated in this study. The changes on body weight were increased significantly in 100 and 500mg/kg of GASSW groups and the changes on body gain were increased significantly in 1000mg/kg of GASSW groups as compared with control group. The changes on the spleen weight (absolutely or relatively) were increased significantly in all GASSW groups as compared with control group. The total blood leukocyte numbers were increased significantly in 1000 and 500mg/kg of GASSW groups as compared with control group. The total lymphocyte numbers were increased significantly in all GASSW groups in the blood and increased significantly in 1000 and 500mg/kg of GASSW goups in spleen as compared with control group. The percentage of B-cell and T-cell were increased significantly in 1000mg/kg of GASSW groups in the blood and increased significantly in 1000 and 500mg/kg of GASSW groups in spleen as compared with control group. The percentage of CD3+CD4+ T-cell and the serum IL-2 levels and productivity of IL-2 of splenic cells were increased significantly in 100 and 500 mg/kg of GASSW groups in the blood and spleen as compared with control group. The percentage of CD3+CD8+ T-cell were increased significantly in 1000mg/kg of GASSW groups only in spleen as compared with control groups. The CD4+/CD8+ T-cell ratios were increased significantly in 1000 and 500mg/kg of GASSW groups only in the blood as compared with control group. Goamshimshinhwan(GASSW) has immuno-stimulating effect on SD rats with deteriorated immunity caused by methotrexate.

Effect of Intestinal Tight Junction Protein Expression on Growth Performance for Eco-friendly Broiler Production: Meta-analysis (친환경 육계 생산을 위한 장 점막 밀접 접합 단백질의 발현량 조절이 생산성에 미치는 효과: Meta-analysis)

  • Jeon, Eun-Jeong;Park, Myung-Sun;Han, Jae-Kyu;Kim, Joung-Yong;Ahn, Sung-Il
    • Korean Journal of Organic Agriculture
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    • v.29 no.1
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    • pp.125-136
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    • 2021
  • In this study, a meta-analysis was performed to determine the correlation between the expression of tight junction protein in the intestine and the productivity of broiler chickens. A total of 9 papers were selected in which the result values consisted of the mean and standard deviation value, and the standardized mean difference was calculated to compare the mean of the control and treatment groups. A meta-regression test was conducted to determine the effect of each type of tight junction protein. The TJPs observed in each study were claudin1, claudin2, claudin3, occludin, ZO1, ZO2, etc., and the indicators to indicate the productivity of broilers were body weight gain (BWG), feed intake (FI), and feed conversion rate (FCR), average daily feed intake (ADFI), average daily gain (ADG), and feed/gain ratio (FPG). Although there are differences depending on the type of TJP, it was found that the change in expression level had a close effect on the productivity of broilers. In particular, occludin significantly correlated with body weight gain, feed intake, and feed conversion rate. Based on the results of this study, a study on a method to effectively increase the expression level of TJP is expected to contribute to improving the productivity of broilers and producing safe livestock products.

Analysis of the Factors Influencing the Efficiency of Natural Recreation Forest Management (자연휴양림 경영효율성에 대한 영향 요인 분석)

  • Seung Yeon Byun;Do-il Yoo;Ja-Choon Koo
    • Journal of Korean Society of Forest Science
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    • v.113 no.2
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    • pp.153-163
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    • 2024
  • Since the onset of the COVID-19 pandemic, there has been a significant shift in the lifestyle patterns of the populace across various domains. Concerns surrounding COVID-19 have emerged as pivotal catalysts of change in recreational habits with people giving a particular preference for environments with low population density and increased openness. This trend has resulted in an uptick in excursions to natural reserves, coastlines, and parks. However, during the peak of infectious outbreaks, widespread adherence to social distancing measures has precipitated a steep decline in tourist footfall across natural recreation forests, exacerbating financial deficits to a considerable extent. Thus, this research sought to compare and analyze the operational efficacy and productivity of national, public, and private natural recreation forests pre- and post-COVID-19 pandemic by utilizing non-parametric methodologies, such as data envelopment analysis and the Malmquist productivity index analysis. The objective was to identify the factors contributing to the decreases in efficiency and productivity and ultimately offer nuanced recommendations tailored to respective administrative bodies. This study's distinctive focus on the analysis of management efficiency and productivity in natural recreation forests nationwide offers significant academic and practical relevance.

The Effect of Kuwonsimsin-hwan on Immunosuppression Induced by Methotrexate in Rat (구원심신환(究原心腎丸)이 methotrexate로 유발된 흰쥐의 면역기능저하(免疫機能低下)에 미치는 영향(影響))

  • Choi, Soon-Ho;Kang, Seok-Bong;Choi, Sun-Mi;Lee, Yeon-Kyeong
    • The Journal of Korean Medicine
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    • v.28 no.2 s.70
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    • pp.126-136
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    • 2007
  • Objectives : In the present study, the effect of Kuwonsimsin-hwan (KSS) was tested in methotrexate (MTX)-induced immunosuppressed SD rats. Methods : Methotrexate was fed to white rats once a day for 4 days. After the immune responses of the rats deteriorated, dried extracts of Kuwonsimsin-hwan mixed in water was fed to the rats once a day for 14 days. We then measured the number of lymphocytes in peripheral blood and the percentage of B-cells, T-cells, CD3+CD4+T-cells, CD3+CD8+ T-cells and IL-2 productivity sampled from spleen and peripheral region. Results : (1) The number of lymphocytes and the percentage of T-cells and CD3+CD4+ T-cellsin peripheral blood increased significantly in the KSS group as compared with the control group. (2) The percentage of B-cells, CD3+CD8+ T-cells, and CD4+/CD8+ T-cells in peripheral blood were not different statistically. (3) The percentage of T-cells in spleen and IL-2 productivity of spleen cells increased significantly in the KSS group as compared with the control group. (4) The percentage of CD3+CD4+ T-cells in spleen increased in KSS the group as compared with the control group but without statistical significance. (5) The percentage of B-cells, CD3+CD8+ T-cells, and CD4+/CD8+ T-cells in spleen were not different statistically. Conclusion : It is concluded that Kuwonsimsin-hwan has immunostimulating effect on MTX-induced immunosuppressed SD rats.

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Development of the Engagement Control Software Architecture Based on UML 2.0 Model (UML 2.0 모델 기반의 교전통제 소프트웨어 아키텍처 개발)

  • Yoo, Myong-Hwan;Bae, Jung-Il;Shin, Jin-Hwa;Cho, Kil-Seok
    • Journal of the Korea Institute of Military Science and Technology
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    • v.10 no.4
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    • pp.20-29
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    • 2007
  • The engagement control software embedded in the weapon control computer of the fire control center for air defense missile system is large-scale real-time software. The use of typical software development methodologies is not appropriate to develop such large-scale embedded software in terms of reusability, reliability, and productivity for the reason that it is significantly complicated, and highly dependent on hardware platforms and developers. In this paper, a model-based software architecture using components based on UML 2.0 for the engagement control software is presented in order to solve these problems. This software architecture is verified using the black-box test, the scenario-based test, and the Ethernet packet monitoring test methods. The results demonstrate that the developed software architecture can be employed to enhance reusability, maintainability, and productivity of large-scale embedded software.

Integrate Processing Scheme of Flow Control Language (흐름 제어 언어의 통합 처리)

  • Kim, Tae-Wan;Chang, Chun-Hyon
    • The KIPS Transactions:PartD
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    • v.11D no.2
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    • pp.415-422
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    • 2004
  • Automation systems improve the productivity of works which relate to product design, facilities management, fault processing and quality evaluation. In these systems, the description language for monitoring and control process is called new control language. These are five flow control languages : IL, ST, FBD, SFC and LD. IL and ST are based on left form. FBD, SFC and LD are based on graphic form. Generally, a software which monitors and controls a system is allowed to use just one flow control language. It is impossible to use more than two languages for simulation in the same system environment. In this paper, we analyzed the characteristics of flow control languages and the process of programming in the legacy system. In addition, for the Integrated processing of languages, we propose Extended ST based on the high-level ST language. Based on this research, we implement a graphical language editor and EST-IL convertor. The graphical language editor makes sequence rules, and converts graphical language into EST. EST-IL convertor has a function to convert EST into IL which is similar to assembly language. As the result of this paper, we present a scheme which integrates all the flow control language processing based on IL.

A Study of a Hydraulic Excavator's Test to Verify of Payload Estimation by Bucket's Motion Equation (유압 굴착기 실험을 통한 작업량 추정법 확인에 관한 연구)

  • Jeong, Hwang Hun;Lee, Min Su;Shin, Young Il
    • Journal of Drive and Control
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    • v.19 no.2
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    • pp.11-16
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    • 2022
  • It is important to measure the excavator's work productivity that estimates the bucket's payloads on a process. If the bucket isn't filled at every working cycle, the excavator's operator has to drive the machine more to achieve his work quota. If bucket is filled over with the load, the other way around, the transferred object has to spread out on the workplace. That causes additional work to clean the site. This paper proposes a method that can estimate the bucket's payload to improve the excavator's work productivity. This method assumes that the excavator is a lumped mass system. And it uses a 3 points angle (boom link, arm link, swing) and 2 points pressure (boom cylinder's input port and output port) of measurable data. Depending on assumptions, the bucket's payload can be calculated by the payload's motion equation. And this suggested method can be verified by simple experiments.