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http://dx.doi.org/10.11625/KJOA.2021.29.1.125

Effect of Intestinal Tight Junction Protein Expression on Growth Performance for Eco-friendly Broiler Production: Meta-analysis  

Jeon, Eun-Jeong (전북대학교 축산학과)
Park, Myung-Sun (전북대학교 축산학과)
Han, Jae-Kyu (전북대학교 축산학과)
Kim, Joung-Yong (전북대학교 축산학과)
Ahn, Sung-Il (전북대학교 농업생명과학대학 동물자원과학과)
Publication Information
Korean Journal of Organic Agriculture / v.29, no.1, 2021 , pp. 125-136 More about this Journal
Abstract
In this study, a meta-analysis was performed to determine the correlation between the expression of tight junction protein in the intestine and the productivity of broiler chickens. A total of 9 papers were selected in which the result values consisted of the mean and standard deviation value, and the standardized mean difference was calculated to compare the mean of the control and treatment groups. A meta-regression test was conducted to determine the effect of each type of tight junction protein. The TJPs observed in each study were claudin1, claudin2, claudin3, occludin, ZO1, ZO2, etc., and the indicators to indicate the productivity of broilers were body weight gain (BWG), feed intake (FI), and feed conversion rate (FCR), average daily feed intake (ADFI), average daily gain (ADG), and feed/gain ratio (FPG). Although there are differences depending on the type of TJP, it was found that the change in expression level had a close effect on the productivity of broilers. In particular, occludin significantly correlated with body weight gain, feed intake, and feed conversion rate. Based on the results of this study, a study on a method to effectively increase the expression level of TJP is expected to contribute to improving the productivity of broilers and producing safe livestock products.
Keywords
broiler; occludin; tight junction protein;
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